𝕏

Task 55444286

Name HuVeMOp_20240630144054798196_ORdGradInc_k_25-Pueyo_APDR-conf_500_0
Workunit 26328326
Created 30 Jun 2024, 12:40:56 UTC
Sent 30 Jun 2024, 14:08:58 UTC
Report deadline 3 Jul 2024, 23:44:58 UTC
Received 1 Jul 2024, 13:15:05 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236597
Run time 2 hours 18 min 25 sec
CPU time 2 hours 16 min 21 sec
Validate state Valid
Credit 61.70
Device peak FLOPS 4.22 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.91 MB
Peak swap size 3.82 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.20.5</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630144054798196_ORdGradInc_k_25-Pueyo_APDR-conf_500.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630144054798196_ORdGradInc_k_25-Pueyo_APDR-conf_500_0_r2061142414_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630144054798196_ORdGradInc_k_25-Pueyo_APDR-conf_500_0_r2061142414_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 101.567791
     * GNaL_b in INaL: 0.007302
     * Gto_b in Ito: 0.070691
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033356
     * GKs_b in IKs: 0.001985
     * GK1_b in IK1: 0.170224
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 68.049334
     * GKb_b in IKb: 0.003769
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.022433
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 16164916, states[0] = -94.727961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32667327, states[0] = -94.732999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48641699, states[0] = -65.802310, states[40]= 0.000002
Saving checkpoint... 
Iteration: 65029366, states[0] = 20.061098, states[40]= 0.006514
Saving checkpoint... 
Iteration: 81046284, states[0] = 13.871694, states[40]= 0.005320
Saving checkpoint... 
Iteration: 97154413, states[0] = -85.065285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113427314, states[0] = -95.080514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129761806, states[0] = -94.989371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145911960, states[0] = -95.075092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161753281, states[0] = -94.978442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177979253, states[0] = -95.087356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194022137, states[0] = 22.329805, states[40]= 0.008663
Saving checkpoint... 
Iteration: 209943065, states[0] = -95.081123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226346703, states[0] = -95.050832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242377914, states[0] = -95.063661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258654067, states[0] = -83.797755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274773405, states[0] = -94.999647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290634842, states[0] = -55.339068, states[40]= 0.000013
Saving checkpoint... 
Iteration: 306713935, states[0] = -94.919606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322693969, states[0] = -94.881467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338826374, states[0] = -95.039956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354795551, states[0] = -95.019069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371273309, states[0] = -94.999468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387183668, states[0] = -94.858871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403243036, states[0] = -94.964573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419577720, states[0] = -0.832491, states[40]= 0.004276
Saving checkpoint... 
Iteration: 435870964, states[0] = -95.060926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451842821, states[0] = -95.048700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468066955, states[0] = 5.014185, states[40]= 0.004902
Saving checkpoint... 
Iteration: 483895363, states[0] = -95.069158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499872177, states[0] = -95.061342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515872706, states[0] = -95.061530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532062169, states[0] = 7.269270, states[40]= 0.005031
Saving checkpoint... 
Iteration: 548316634, states[0] = -95.033896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564442773, states[0] = -95.080676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580700711, states[0] = -94.894784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597378206, states[0] = -95.063477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613674716, states[0] = -94.816674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629809079, states[0] = -95.028842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645978720, states[0] = -95.086562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662170304, states[0] = -94.726401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678841710, states[0] = -95.048006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695203824, states[0] = -94.900736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711417037, states[0] = -95.074936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727319913, states[0] = -95.035842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743334635, states[0] = -95.044304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760017597, states[0] = 23.442837, states[40]= 0.012961
Saving checkpoint... 
Iteration: 776207849, states[0] = -94.908275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792313732, states[0] = -95.031866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808457054, states[0] = -95.083123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825214652, states[0] = -94.920533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841538263, states[0] = 17.104171, states[40]= 0.005638
Saving checkpoint... 
Iteration: 857578980, states[0] = -1.622163, states[40]= 0.004150
Saving checkpoint... 
Iteration: 873971484, states[0] = -95.085380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889814582, states[0] = -95.032361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905961767, states[0] = -95.083847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922159070, states[0] = -91.167539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937991274, states[0] = -95.088025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954341569, states[0] = -95.047764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970348441, states[0] = -95.051084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986496509, states[0] = -95.088625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002415991, states[0] = -95.074496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018185136, states[0] = -94.862036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034419829, states[0] = -95.075415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050273265, states[0] = -94.998999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066394888, states[0] = -95.068652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082485992, states[0] = -95.087267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098567675, states[0] = 4.661079, states[40]= 0.004878
Saving checkpoint... 
Iteration: 1115121766, states[0] = -40.672044, states[40]= 0.000127
Saving checkpoint... 
Iteration: 1131245791, states[0] = -94.967753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147379886, states[0] = -95.063724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163501264, states[0] = 49.006287, states[40]= 0.049334
Saving checkpoint... 
Iteration: 1179751371, states[0] = -94.974784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196173124, states[0] = -94.795948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212332951, states[0] = -95.043103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228565681, states[0] = 5.629729, states[40]= 0.004942
Saving checkpoint... 
Iteration: 1244843476, states[0] = -95.048529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260815822, states[0] = -95.032931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277325820, states[0] = -95.039045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293425286, states[0] = -95.076533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309320148, states[0] = -95.035624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325674291, states[0] = -94.811621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341669027, states[0] = -94.667960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357641554, states[0] = -63.672283, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1374151983, states[0] = -79.943317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390550034, states[0] = 12.484314, states[40]= 0.005236
Saving checkpoint... 
Iteration: 1406322290, states[0] = -95.036870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422655819, states[0] = -86.839770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439109892, states[0] = -28.870289, states[40]= 0.000549
Saving checkpoint... 
Iteration: 1455569537, states[0] = 3.727465, states[40]= 0.004806
Saving checkpoint... 
Iteration: 1471661700, states[0] = -93.115178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488198934, states[0] = -94.890718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1504501499, states[0] = 49.003427, states[40]= 0.040792
Saving checkpoint... 
Iteration: 1520527273, states[0] = -70.608628, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1536517800, states[0] = -95.250007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1552641305, states[0] = -93.805193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1568619342, states[0] = -95.266106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1584717162, states[0] = -58.594615, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1601163194, states[0] = 0.126632, states[40]= 0.004969
Saving checkpoint... 
Iteration: 1617044816, states[0] = 11.036474, states[40]= 0.006102
Saving checkpoint... 
Iteration: 1633203847, states[0] = 35.914850, states[40]= 0.127656
Saving checkpoint... 
Iteration: 1649677841, states[0] = -95.336985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1665706610, states[0] = -45.314305, states[40]= 0.000066
Saving checkpoint... 
Iteration: 1681524370, states[0] = 20.587567, states[40]= 0.008872
Saving checkpoint... 
Iteration: 1697524889, states[0] = -70.361598, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1713661584, states[0] = 1.166202, states[40]= 0.005128
Saving checkpoint... 
Iteration: 1729508536, states[0] = 26.948515, states[40]= 0.071048
Saving checkpoint... 
Iteration: 1745400766, states[0] = 43.389084, states[40]= 0.009440
Saving checkpoint... 
Iteration: 1761755841, states[0] = -95.133675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1777857925, states[0] = 3.548243, states[40]= 0.005424
Saving checkpoint... 
Iteration: 1793903336, states[0] = -95.248030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1809680474, states[0] = -94.889061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1825482900, states[0] = -95.116791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1842296910, states[0] = -95.038013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1858237900, states[0] = -94.968528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1874462097, states[0] = -95.090582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1890323706, states[0] = -95.041997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1906348630, states[0] = -95.053437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1922575575, states[0] = 0.390760, states[40]= 0.004453
Saving checkpoint... 
Iteration: 1938873850, states[0] = -95.062140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1955025891, states[0] = 21.277150, states[40]= 0.007241
Saving checkpoint... 
Iteration: 1970881689, states[0] = -95.064224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1986529921, states[0] = 20.029453, states[40]= 0.006441
Saving checkpoint... 
Iteration: 2002440645, states[0] = -95.079486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2018670822, states[0] = -94.743486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2034745855, states[0] = -94.967286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050745245, states[0] = -94.966454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2066599613, states[0] = -18.982720, states[40]= 0.001076
Saving checkpoint... 
Iteration: 2082786030, states[0] = -95.010098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2099032144, states[0] = 19.292013, states[40]= 0.006150
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.964166
 - CaMKt in component CaMK (millimolar): 0.007077
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.647832
 - nass in component intracellular_ions (millimolar): 6.647893
 - ki in component intracellular_ions (millimolar): 145.326889
 - kss in component intracellular_ions (millimolar): 145.326869
 - cansr in component intracellular_ions (millimolar): 1.326077
 - cajsr in component intracellular_ions (millimolar): 1.288144
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003596
 - hf in component INa (dimensionless): 0.881078
 - hs in component INa (dimensionless): 0.881073
 - j in component INa (dimensionless): 0.881045
 - hsp in component INa (dimensionless): 0.727864
 - jp in component INa (dimensionless): 0.881027
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.712103
 - hLp in component INaL (dimensionless): 0.455552
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.622843
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.697518
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.931916
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999878
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001675
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.339669
 - xs1 in component IKs (dimensionless): 0.243946
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997321
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:14:50 (97324): called boinc_finish(0)

</stderr_txt>
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