𝕏

Task 55442908

Name HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_887_1
Workunit 26327657
Created 30 Jun 2024, 12:21:12 UTC
Sent 30 Jun 2024, 14:01:01 UTC
Report deadline 3 Jul 2024, 23:37:01 UTC
Received 3 Jul 2024, 20:51:12 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232764
Run time 2 hours 39 min 7 sec
CPU time 2 hours 39 min 7 sec
Validate state Valid
Credit 63.11
Device peak FLOPS 3.99 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.71 MB
Peak swap size 5.31 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_887.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_887_1_r552579974_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_887_1_r552579974_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 117.139863
     * GNaL_b in INaL: 0.006011
     * Gto_b in Ito: 0.076912
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034107
     * GKs_b in IKs: 0.002053
     * GK1_b in IK1: 0.149797
     * Gncx_b in INaCa_i: 0.000956
     * Pnak_b in INaK: 71.050154
     * GKb_b in IKb: 0.003693
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028967
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12105861, states[0] = -36.196901, states[40]= 0.000196
Saving checkpoint... 
Iteration: 23868683, states[0] = -95.056738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35556357, states[0] = 7.108780, states[40]= 0.005047
Saving checkpoint... 
Iteration: 47257570, states[0] = -94.937715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58521017, states[0] = 21.058179, states[40]= 0.009808
Saving checkpoint... 
Iteration: 70037733, states[0] = 15.543671, states[40]= 0.005742
Saving checkpoint... 
Iteration: 81743740, states[0] = -94.897540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93332681, states[0] = -94.976216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104634638, states[0] = -63.200228, states[40]= 0.000003
Saving checkpoint... 
Iteration: 116689565, states[0] = -94.790686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128852118, states[0] = -94.980907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140854816, states[0] = -94.981288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153310985, states[0] = -94.955276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165108779, states[0] = -33.896118, states[40]= 0.000282
Saving checkpoint... 
Iteration: 177064921, states[0] = 3.825360, states[40]= 0.004799
Saving checkpoint... 
Iteration: 189388914, states[0] = -94.993218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201036188, states[0] = 16.338330, states[40]= 0.005866
Saving checkpoint... 
Iteration: 213791375, states[0] = -94.938625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225925857, states[0] = -95.003382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238412021, states[0] = -94.999802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250822719, states[0] = -94.961731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262939892, states[0] = -95.006381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275165485, states[0] = -94.534907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287199999, states[0] = -94.808986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298720242, states[0] = -94.848141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310139044, states[0] = -68.341879, states[40]= 0.000001
Saving checkpoint... 
Iteration: 321687873, states[0] = -94.782393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333277860, states[0] = -94.925788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344958453, states[0] = -95.009842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356585874, states[0] = -10.713441, states[40]= 0.002262
Saving checkpoint... 
Iteration: 368032914, states[0] = 17.545178, states[40]= 0.006200
Saving checkpoint... 
Iteration: 379900240, states[0] = -94.996228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391342558, states[0] = -94.973010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403023746, states[0] = 20.512269, states[40]= 0.008304
Saving checkpoint... 
Iteration: 414321686, states[0] = -94.960900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425982865, states[0] = -95.013616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437719397, states[0] = -94.846542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448093748, states[0] = -18.496831, states[40]= 0.001094
Saving checkpoint... 
Iteration: 459444729, states[0] = -95.007203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470846790, states[0] = -94.975134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482243419, states[0] = -94.884764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494222522, states[0] = -94.852005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506712296, states[0] = -94.833420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519074135, states[0] = -1.426696, states[40]= 0.004171
Saving checkpoint... 
Iteration: 531046632, states[0] = 12.175013, states[40]= 0.005299
Saving checkpoint... 
Iteration: 543230387, states[0] = -94.865103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555033828, states[0] = 17.215969, states[40]= 0.006095
Saving checkpoint... 
Iteration: 567410768, states[0] = -94.999159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580409202, states[0] = -94.998719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592970129, states[0] = -95.011641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604973459, states[0] = -95.012149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617182441, states[0] = -94.768885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629299870, states[0] = -94.945192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641348402, states[0] = -94.975844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652615356, states[0] = -40.729994, states[40]= 0.000110
Saving checkpoint... 
Iteration: 663794291, states[0] = -94.940614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676063598, states[0] = 4.512492, states[40]= 0.004851
Saving checkpoint... 
Iteration: 688131306, states[0] = -58.768018, states[40]= 0.000006
Saving checkpoint... 
Iteration: 699818292, states[0] = -94.958532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711472409, states[0] = -95.011930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722845697, states[0] = -94.974444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734206758, states[0] = -94.822518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745832992, states[0] = -94.967573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758010701, states[0] = 24.005316, states[40]= 0.046772
Saving checkpoint... 
Iteration: 769659291, states[0] = -93.573022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781182079, states[0] = -94.767817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793028202, states[0] = 19.152306, states[40]= 0.006954
Saving checkpoint... 
Iteration: 804700640, states[0] = -94.810010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815857932, states[0] = -94.980251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827303178, states[0] = -94.947670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838692257, states[0] = -94.791993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850128323, states[0] = -55.286451, states[40]= 0.000011
Saving checkpoint... 
Iteration: 861796982, states[0] = -94.942736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872917293, states[0] = -95.000729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884379306, states[0] = -94.988946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896049954, states[0] = 10.772244, states[40]= 0.005205
Saving checkpoint... 
Iteration: 907825197, states[0] = -94.962839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919214654, states[0] = -94.837630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930457796, states[0] = -95.009401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942085422, states[0] = -10.291645, states[40]= 0.002349
Saving checkpoint... 
Iteration: 954688551, states[0] = -94.783594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966784610, states[0] = -94.931904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978818476, states[0] = -94.958501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990493060, states[0] = -95.014657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002383080, states[0] = -94.990248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014604993, states[0] = -29.953019, states[40]= 0.000442
Saving checkpoint... 
Iteration: 1026009189, states[0] = 24.738076, states[40]= 0.065273
Saving checkpoint... 
Iteration: 1037955964, states[0] = -95.009016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050638565, states[0] = -67.706910, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1062440524, states[0] = -95.006017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074489133, states[0] = -95.014107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086075424, states[0] = -2.277832, states[40]= 0.004028
Saving checkpoint... 
Iteration: 1097612657, states[0] = -37.868489, states[40]= 0.000166
Saving checkpoint... 
Iteration: 1109388582, states[0] = -94.992097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121985587, states[0] = -95.013609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133821014, states[0] = -94.960073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145876288, states[0] = -94.987674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157673416, states[0] = -94.729776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169643070, states[0] = -74.004886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181454169, states[0] = -95.008612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193347675, states[0] = -94.975181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205433250, states[0] = -95.004375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216953891, states[0] = -95.008542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228391151, states[0] = -94.992889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240029110, states[0] = 18.855375, states[40]= 0.006773
Saving checkpoint... 
Iteration: 1251630066, states[0] = -57.313470, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1263157096, states[0] = -92.646135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274935330, states[0] = -95.004795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286617545, states[0] = -43.096502, states[40]= 0.000078
Saving checkpoint... 
Iteration: 1297792643, states[0] = -94.938870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309322921, states[0] = -94.961195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321751126, states[0] = -94.894751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334141081, states[0] = -71.122520, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1346415662, states[0] = -95.000046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357703235, states[0] = -94.815064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369715500, states[0] = -94.838951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381748583, states[0] = -94.891361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393449419, states[0] = -95.007609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405408830, states[0] = -94.998165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417776034, states[0] = -94.923357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429743898, states[0] = -94.884917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441772270, states[0] = -94.919466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453473516, states[0] = -95.011694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465180991, states[0] = -94.764385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477332223, states[0] = -94.966730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488645244, states[0] = -77.356142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1500116967, states[0] = -49.218908, states[40]= 0.000029
Saving checkpoint... 
Iteration: 1511040865, states[0] = -95.218245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1522238805, states[0] = 13.155322, states[40]= 0.006461
Saving checkpoint... 
Iteration: 1533835411, states[0] = -95.238157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1545025939, states[0] = 18.908691, states[40]= 0.008664
Saving checkpoint... 
Iteration: 1557141982, states[0] = -94.639426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1568656275, states[0] = -95.282217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579709696, states[0] = -95.222219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1590364180, states[0] = -3.366106, states[40]= 0.004272
Saving checkpoint... 
Iteration: 1601611435, states[0] = -95.228676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1613540744, states[0] = -94.564555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1625454756, states[0] = 3.465302, states[40]= 0.005380
Saving checkpoint... 
Iteration: 1637252755, states[0] = -95.081932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1648902743, states[0] = -47.306743, states[40]= 0.000043
Saving checkpoint... 
Iteration: 1660550563, states[0] = 6.056908, states[40]= 0.005660
Saving checkpoint... 
Iteration: 1672481402, states[0] = -95.314343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1684613862, states[0] = -61.735065, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1696962111, states[0] = -95.121859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1709242581, states[0] = -94.789223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1721379226, states[0] = -95.312830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1733758022, states[0] = 1.239898, states[40]= 0.005096
Saving checkpoint... 
Iteration: 1745983615, states[0] = -95.316323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1757913341, states[0] = -95.235110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1769124890, states[0] = 19.140786, states[40]= 0.009016
Saving checkpoint... 
Iteration: 1781400180, states[0] = -73.201970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1793587091, states[0] = -95.184756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1805649573, states[0] = -90.156072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1817515041, states[0] = 22.397179, states[40]= 0.019603
Saving checkpoint... 
Iteration: 1829544110, states[0] = 12.730014, states[40]= 0.005398
Saving checkpoint... 
Iteration: 1841570083, states[0] = 0.420138, states[40]= 0.004463
Saving checkpoint... 
Iteration: 1853165990, states[0] = -94.625710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1865458389, states[0] = -95.020945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1878254339, states[0] = -94.906876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1890407280, states[0] = -95.003175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1902115267, states[0] = -40.876459, states[40]= 0.000108
Saving checkpoint... 
Iteration: 1913656519, states[0] = -92.426743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1925360941, states[0] = -94.983009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1937347217, states[0] = -94.975960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1948541685, states[0] = 14.186232, states[40]= 0.005499
Saving checkpoint... 
Iteration: 1959682051, states[0] = -94.767828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1970940308, states[0] = -95.005977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1982505350, states[0] = 29.596458, states[40]= 0.133109
Saving checkpoint... 
Iteration: 1993745575, states[0] = -94.887180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2005420479, states[0] = -95.001076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2016591720, states[0] = -16.449313, states[40]= 0.001314
Saving checkpoint... 
Iteration: 2027790126, states[0] = -94.936353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2039327546, states[0] = -94.963687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2051036952, states[0] = 16.053176, states[40]= 0.005802
Saving checkpoint... 
Iteration: 2062307769, states[0] = -94.950438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2073643020, states[0] = -73.931416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2085204057, states[0] = -94.816315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2096850061, states[0] = -94.975831, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.890741
 - CaMKt in component CaMK (millimolar): 0.006648
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.538860
 - nass in component intracellular_ions (millimolar): 6.538921
 - ki in component intracellular_ions (millimolar): 145.441926
 - kss in component intracellular_ions (millimolar): 145.441905
 - cansr in component intracellular_ions (millimolar): 1.301462
 - cajsr in component intracellular_ions (millimolar): 1.264543
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003623
 - hf in component INa (dimensionless): 0.879808
 - hs in component INa (dimensionless): 0.879803
 - j in component INa (dimensionless): 0.879774
 - hsp in component INa (dimensionless): 0.725466
 - jp in component INa (dimensionless): 0.879754
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.711255
 - hLp in component INaL (dimensionless): 0.456628
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.628670
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.704634
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.938362
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999898
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001578
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.334910
 - xs1 in component IKs (dimensionless): 0.231404
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997340
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
14:50:56 (7312): called boinc_finish(0)

</stderr_txt>
]]>


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