𝕏

Task 55442903

Name HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0
Workunit 26327655
Created 30 Jun 2024, 12:21:12 UTC
Sent 30 Jun 2024, 13:58:36 UTC
Report deadline 3 Jul 2024, 23:34:36 UTC
Received 1 Jul 2024, 3:31:04 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 234076
Run time 2 hours 11 min 53 sec
CPU time 1 hours 28 min 38 sec
Validate state Valid
Credit 63.53
Device peak FLOPS 4.45 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.70 MB
Peak swap size 5.30 MB
Peak disk usage 0.32 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 118.178291
     * GNaL_b in INaL: 0.006570
     * Gto_b in Ito: 0.082181
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030208
     * GKs_b in IKs: 0.002082
     * GK1_b in IK1: 0.181292
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 69.242653
     * GKb_b in IKb: 0.003761
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033365
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9522044, states[0] = 20.546483, states[40]= 0.008896
Saving checkpoint... 
Iteration: 29348273, states[0] = -95.186247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41413059, states[0] = -95.195035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53135414, states[0] = -51.997336, states[40]= 0.000022
Saving checkpoint... 
Iteration: 70420040, states[0] = -95.181774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87044608, states[0] = 14.386806, states[40]= 0.005211


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 118.178291
     * GNaL_b in INaL: 0.006570
     * Gto_b in Ito: 0.082181
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030208
     * GKs_b in IKs: 0.002082
     * GK1_b in IK1: 0.181292
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 69.242653
     * GKb_b in IKb: 0.003761
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033365
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 87044608
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 14.386806 (After loading)
 - states[40]: 0.005211 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 103291067, states[0] = -95.119184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114140437, states[0] = -56.191133, states[40]= 0.000011
Saving checkpoint... 
Iteration: 124598707, states[0] = -15.310901, states[40]= 0.001428
Saving checkpoint... 
Iteration: 141597711, states[0] = -14.355704, states[40]= 0.001559
Saving checkpoint... 
Iteration: 157443465, states[0] = -95.176693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173954838, states[0] = -95.178311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189729717, states[0] = -95.050462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206584503, states[0] = -3.758166, states[40]= 0.003642
Saving checkpoint... 
Iteration: 223681683, states[0] = -94.959171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240059317, states[0] = 8.867492, states[40]= 0.004941
Saving checkpoint... 
Iteration: 259345464, states[0] = -95.147139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277763893, states[0] = -95.091169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292346687, states[0] = -95.147637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309620385, states[0] = -35.016227, states[40]= 0.000274
Saving checkpoint... 
Iteration: 326878728, states[0] = -95.159831, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 118.178291
     * GNaL_b in INaL: 0.006570
     * Gto_b in Ito: 0.082181
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030208
     * GKs_b in IKs: 0.002082
     * GK1_b in IK1: 0.181292
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 69.242653
     * GKb_b in IKb: 0.003761
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033365
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 326878728
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.159831 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 118.178291
     * GNaL_b in INaL: 0.006570
     * Gto_b in Ito: 0.082181
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030208
     * GKs_b in IKs: 0.002082
     * GK1_b in IK1: 0.181292
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 69.242653
     * GKb_b in IKb: 0.003761
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033365
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 326878728
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.159831 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 342462988, states[0] = -95.178974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343409596, states[0] = -95.168596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346339053, states[0] = -95.144089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351010880, states[0] = 23.739564, states[40]= 0.044837
Saving checkpoint... 
Iteration: 353263171, states[0] = -95.090373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358871219, states[0] = -95.157265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361751493, states[0] = -95.077809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366554277, states[0] = 10.872208, states[40]= 0.005012
Saving checkpoint... 
Iteration: 371153704, states[0] = -73.804981, states[40]= 0.000001
Saving checkpoint... 
Iteration: 375027601, states[0] = 20.089356, states[40]= 0.006776
Saving checkpoint... 
Iteration: 379855695, states[0] = -95.151389, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 118.178291
     * GNaL_b in INaL: 0.006570
     * Gto_b in Ito: 0.082181
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030208
     * GKs_b in IKs: 0.002082
     * GK1_b in IK1: 0.181292
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 69.242653
     * GKb_b in IKb: 0.003761
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033365
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 379855695
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.151389 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 385209383, states[0] = -95.018255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390172349, states[0] = -94.737796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394787342, states[0] = -95.112038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396696954, states[0] = -94.996025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401367272, states[0] = -95.155828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407414795, states[0] = -95.169803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412155541, states[0] = -77.072191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413976887, states[0] = -95.180895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419394797, states[0] = -95.164652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424689140, states[0] = -94.980662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428902892, states[0] = -95.166843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432881980, states[0] = -95.160810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436697905, states[0] = -94.997774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441044250, states[0] = 14.645624, states[40]= 0.005219
Saving checkpoint... 
Iteration: 445264440, states[0] = -95.091593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449299771, states[0] = -95.121257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453397113, states[0] = -95.165277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458606164, states[0] = -21.935791, states[40]= 0.000881
Saving checkpoint... 
Iteration: 463278699, states[0] = -95.104846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467266729, states[0] = -95.093842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471723751, states[0] = -95.041247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475650819, states[0] = -69.194642, states[40]= 0.000001
Saving checkpoint... 
Iteration: 481290292, states[0] = -95.114288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486993610, states[0] = -95.182906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491941960, states[0] = -95.175389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495918863, states[0] = -95.170687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499820430, states[0] = -95.134286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503442185, states[0] = -95.175423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508433302, states[0] = -95.173733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514101255, states[0] = -17.465911, states[40]= 0.001186
Saving checkpoint... 
Iteration: 518684506, states[0] = -94.969290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523200815, states[0] = -95.003073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527318138, states[0] = -95.132949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532219551, states[0] = -95.034778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536788673, states[0] = -95.113001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540769034, states[0] = -95.096023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545718807, states[0] = -95.033604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549908897, states[0] = -95.168300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553640666, states[0] = -56.137669, states[40]= 0.000011
Saving checkpoint... 
Iteration: 558299549, states[0] = -95.121038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563094357, states[0] = -11.314425, states[40]= 0.002070
Saving checkpoint... 
Iteration: 568535043, states[0] = 17.841638, states[40]= 0.005738
Saving checkpoint... 
Iteration: 573546610, states[0] = 13.779048, states[40]= 0.005151
Saving checkpoint... 
Iteration: 578037637, states[0] = 16.977659, states[40]= 0.005537
Saving checkpoint... 
Iteration: 581850524, states[0] = -95.149118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585901732, states[0] = -95.166447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590740918, states[0] = -95.064937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595166228, states[0] = -93.223619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598727594, states[0] = -95.046842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602366279, states[0] = -95.155347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606955973, states[0] = -95.177725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610842581, states[0] = -95.145582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615279201, states[0] = -95.105190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619687790, states[0] = -94.977596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623002337, states[0] = 44.075407, states[40]= 0.094749
Saving checkpoint... 
Iteration: 627563605, states[0] = 7.085798, states[40]= 0.004867
Saving checkpoint... 
Iteration: 632462568, states[0] = -95.178738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636065862, states[0] = 6.109654, states[40]= 0.004818
Saving checkpoint... 
Iteration: 640802586, states[0] = -95.123086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644871333, states[0] = -95.157136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649950814, states[0] = -95.176851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653906981, states[0] = -95.167761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658079164, states[0] = -0.465528, states[40]= 0.004198
Saving checkpoint... 
Iteration: 662087988, states[0] = -6.194595, states[40]= 0.003143
Saving checkpoint... 
Iteration: 666523451, states[0] = 21.150977, states[40]= 0.008059
Saving checkpoint... 
Iteration: 671285695, states[0] = -95.110561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675955094, states[0] = -95.177543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680392875, states[0] = -95.163954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684797782, states[0] = -95.119716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689181186, states[0] = -94.956266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693287607, states[0] = -95.112073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697448397, states[0] = -95.176411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701866906, states[0] = -95.155519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706603995, states[0] = -19.960839, states[40]= 0.000991
Saving checkpoint... 
Iteration: 711457242, states[0] = -95.177867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715070983, states[0] = 3.772766, states[40]= 0.004662
Saving checkpoint... 
Iteration: 719110947, states[0] = -26.291965, states[40]= 0.000680
Saving checkpoint... 
Iteration: 723775585, states[0] = -95.101959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728762462, states[0] = -95.089431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733894787, states[0] = -95.164466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738512554, states[0] = 23.316092, states[40]= 0.031221
Saving checkpoint... 
Iteration: 744536514, states[0] = 17.355901, states[40]= 0.005617
Saving checkpoint... 
Iteration: 748258067, states[0] = -95.084835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751762301, states[0] = -95.089253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756648275, states[0] = -65.567625, states[40]= 0.000002
Saving checkpoint... 
Iteration: 761770848, states[0] = -95.097608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766150814, states[0] = -69.186737, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 118.178291
     * GNaL_b in INaL: 0.006570
     * Gto_b in Ito: 0.082181
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030208
     * GKs_b in IKs: 0.002082
     * GK1_b in IK1: 0.181292
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 69.242653
     * GKb_b in IKb: 0.003761
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033365
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 766150814
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -69.186737 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 769936250, states[0] = -95.174156, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 118.178291
     * GNaL_b in INaL: 0.006570
     * Gto_b in Ito: 0.082181
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030208
     * GKs_b in IKs: 0.002082
     * GK1_b in IK1: 0.181292
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 69.242653
     * GKb_b in IKb: 0.003761
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033365
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 769936250
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.174156 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 774492366, states[0] = -95.182597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776541810, states[0] = 15.524557, states[40]= 0.005311
Saving checkpoint... 
Iteration: 781385708, states[0] = -95.161770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785223665, states[0] = -95.040935, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 118.178291
     * GNaL_b in INaL: 0.006570
     * Gto_b in Ito: 0.082181
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030208
     * GKs_b in IKs: 0.002082
     * GK1_b in IK1: 0.181292
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 69.242653
     * GKb_b in IKb: 0.003761
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033365
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 785223665
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.040935 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 789841510, states[0] = -95.144983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793942124, states[0] = -95.175243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796215715, states[0] = -95.028529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800694141, states[0] = -94.990455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805150646, states[0] = -68.935995, states[40]= 0.000001
Saving checkpoint... 
Iteration: 809879843, states[0] = -95.159906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815655328, states[0] = -76.679072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820135443, states[0] = -50.263731, states[40]= 0.000028
Saving checkpoint... 
Iteration: 824391633, states[0] = -95.163512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829170073, states[0] = -94.477097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832492967, states[0] = -95.182632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837708765, states[0] = -95.016933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842103078, states[0] = -19.125461, states[40]= 0.001048
Saving checkpoint... 
Iteration: 846751996, states[0] = -95.078096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848690254, states[0] = -94.982740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854613032, states[0] = -28.198915, states[40]= 0.000585
Saving checkpoint... 
Iteration: 859911647, states[0] = -95.168791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863418408, states[0] = -95.170371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867152930, states[0] = -72.506844, states[40]= 0.000001
Saving checkpoint... 
Iteration: 871746575, states[0] = -95.071756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875496767, states[0] = -95.183034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879690645, states[0] = -94.983521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883625522, states[0] = -39.947528, states[40]= 0.000138
Saving checkpoint... 
Iteration: 887657443, states[0] = -80.699447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891545762, states[0] = 14.092128, states[40]= 0.005173
Saving checkpoint... 
Iteration: 896016290, states[0] = 22.614642, states[40]= 0.015953
Saving checkpoint... 
Iteration: 900601994, states[0] = -18.138194, states[40]= 0.001125
Saving checkpoint... 
Iteration: 904562198, states[0] = 7.680597, states[40]= 0.004894
Saving checkpoint... 
Iteration: 908624715, states[0] = -39.157752, states[40]= 0.000154
Saving checkpoint... 
Iteration: 912638522, states[0] = -53.688458, states[40]= 0.000016
Saving checkpoint... 
Iteration: 917620515, states[0] = -35.137543, states[40]= 0.000269
Saving checkpoint... 
Iteration: 921608503, states[0] = -24.064235, states[40]= 0.000783
Saving checkpoint... 
Iteration: 925571045, states[0] = 3.743306, states[40]= 0.004660
Saving checkpoint... 
Iteration: 927831405, states[0] = -95.139970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932816791, states[0] = -95.131923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936574558, states[0] = 2.013278, states[40]= 0.004501
Saving checkpoint... 
Iteration: 940685003, states[0] = -94.970476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944653300, states[0] = -73.120891, states[40]= 0.000001
Saving checkpoint... 
Iteration: 949978061, states[0] = -95.180738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954460468, states[0] = -95.178231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958862904, states[0] = -95.153880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963284245, states[0] = -95.109215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967042349, states[0] = 15.332113, states[40]= 0.005288
Saving checkpoint... 
Iteration: 971574320, states[0] = 2.134379, states[40]= 0.004514
Saving checkpoint... 
Iteration: 976137207, states[0] = -52.213358, states[40]= 0.000021
Saving checkpoint... 
Iteration: 980990893, states[0] = -95.182307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985549074, states[0] = 12.860389, states[40]= 0.005096
Saving checkpoint... 
Iteration: 990123789, states[0] = -38.259178, states[40]= 0.000175
Saving checkpoint... 
Iteration: 994127341, states[0] = -41.752816, states[40]= 0.000106
Saving checkpoint... 
Iteration: 998212814, states[0] = -95.023663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000051389, states[0] = 11.984437, states[40]= 0.005055
Saving checkpoint... 
Iteration: 1004152130, states[0] = -71.214112, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1009341925, states[0] = -95.145048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013587711, states[0] = -5.990425, states[40]= 0.003186
Saving checkpoint... 
Iteration: 1017719693, states[0] = -95.034716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022357220, states[0] = -95.151628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027669402, states[0] = -94.353689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032046148, states[0] = 13.949878, states[40]= 0.005163
Saving checkpoint... 
Iteration: 1033950537, states[0] = -95.176581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038767945, states[0] = -95.094688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043115242, states[0] = -30.229806, states[40]= 0.000483
Saving checkpoint... 
Iteration: 1047277492, states[0] = -95.103455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051488665, states[0] = -95.182004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055295437, states[0] = -95.117808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059293658, states[0] = -95.116495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063216065, states[0] = -95.028937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066897682, states[0] = -95.165077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071190130, states[0] = -94.982354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074819310, states[0] = -95.133310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079001295, states[0] = 51.468636, states[40]= 0.040996
Saving checkpoint... 
Iteration: 1080593228, states[0] = -10.353012, states[40]= 0.002258
Saving checkpoint... 
Iteration: 1085251094, states[0] = -95.076928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089464835, states[0] = -95.178812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094245484, states[0] = -95.070310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098167428, states[0] = -93.785737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102548107, states[0] = 13.222587, states[40]= 0.005116


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 118.178291
     * GNaL_b in INaL: 0.006570
     * Gto_b in Ito: 0.082181
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030208
     * GKs_b in IKs: 0.002082
     * GK1_b in IK1: 0.181292
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 69.242653
     * GKb_b in IKb: 0.003761
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033365
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1102548107
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 13.222587 (After loading)
 - states[40]: 0.005116 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1105679280, states[0] = -94.943332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110646498, states[0] = -63.214397, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1115433011, states[0] = -95.173322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120081100, states[0] = -1.597528, states[40]= 0.004026
Saving checkpoint... 
Iteration: 1125114932, states[0] = -29.944173, states[40]= 0.000497
Saving checkpoint... 
Iteration: 1127669503, states[0] = -94.373961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133467271, states[0] = -95.179144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138143041, states[0] = -58.929249, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1142091721, states[0] = -9.102366, states[40]= 0.002517
Saving checkpoint... 
Iteration: 1144427371, states[0] = -95.172158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149965529, states[0] = -95.178880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153816748, states[0] = -95.131769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159363267, states[0] = -95.153901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163987957, states[0] = -95.181854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168517843, states[0] = 22.331381, states[40]= 0.012924


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 118.178291
     * GNaL_b in INaL: 0.006570
     * Gto_b in Ito: 0.082181
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030208
     * GKs_b in IKs: 0.002082
     * GK1_b in IK1: 0.181292
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 69.242653
     * GKb_b in IKb: 0.003761
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033365
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1168517843
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 22.331381 (After loading)
 - states[40]: 0.012924 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1173370455, states[0] = -95.156520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178512367, states[0] = 23.357216, states[40]= 0.032463
Saving checkpoint... 
Iteration: 1183005756, states[0] = 28.030391, states[40]= 0.131316


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 118.178291
     * GNaL_b in INaL: 0.006570
     * Gto_b in Ito: 0.082181
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030208
     * GKs_b in IKs: 0.002082
     * GK1_b in IK1: 0.181292
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 69.242653
     * GKb_b in IKb: 0.003761
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033365
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1183005756
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 28.030391 (After loading)
 - states[40]: 0.131316 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1186984378, states[0] = -95.181405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191372480, states[0] = -95.157218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194932366, states[0] = -95.173148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201882774, states[0] = -95.160614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206482062, states[0] = -95.181104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211419373, states[0] = -95.170386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215741421, states[0] = -95.065209, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 118.178291
     * GNaL_b in INaL: 0.006570
     * Gto_b in Ito: 0.082181
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030208
     * GKs_b in IKs: 0.002082
     * GK1_b in IK1: 0.181292
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 69.242653
     * GKb_b in IKb: 0.003761
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033365
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1215741421
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.065209 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1221485757, states[0] = -95.181555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226477094, states[0] = -95.180450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231075900, states[0] = 1.318714, states[40]= 0.004426
Saving checkpoint... 
Iteration: 1235539303, states[0] = 16.406065, states[40]= 0.005435
Saving checkpoint... 
Iteration: 1241032367, states[0] = 18.693792, states[40]= 0.006012
Saving checkpoint... 
Iteration: 1242913810, states[0] = -95.169085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245077188, states[0] = 0.631740, states[40]= 0.004344
Saving checkpoint... 
Iteration: 1250067936, states[0] = 5.185699, states[40]= 0.004763
Saving checkpoint... 
Iteration: 1254950674, states[0] = -95.176476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260297620, states[0] = -95.119265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265488035, states[0] = -95.181805, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 118.178291
     * GNaL_b in INaL: 0.006570
     * Gto_b in Ito: 0.082181
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030208
     * GKs_b in IKs: 0.002082
     * GK1_b in IK1: 0.181292
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 69.242653
     * GKb_b in IKb: 0.003761
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033365
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1265488035
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.181805 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1267883746, states[0] = -95.160880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271949657, states[0] = -95.176293, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_486_0_r750381102_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 118.178291
     * GNaL_b in INaL: 0.006570
     * Gto_b in Ito: 0.082181
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030208
     * GKs_b in IKs: 0.002082
     * GK1_b in IK1: 0.181292
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 69.242653
     * GKb_b in IKb: 0.003761
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033365
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1271949657
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.176293 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1276880544, states[0] = -95.159861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278920267, states[0] = -95.170547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284401585, states[0] = -95.166002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289791026, states[0] = -95.114379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292004590, states[0] = 31.115271, states[40]= 0.146070
Saving checkpoint... 
Iteration: 1296931858, states[0] = -95.172987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302180074, states[0] = -94.949241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306919703, states[0] = -95.170405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312206824, states[0] = -95.013304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317621642, states[0] = -36.203352, states[40]= 0.000233
Saving checkpoint... 
Iteration: 1322487354, states[0] = -95.181690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327595940, states[0] = -12.690913, states[40]= 0.001821
Saving checkpoint... 
Iteration: 1329037454, states[0] = 17.039833, states[40]= 0.005550
Saving checkpoint... 
Iteration: 1335772042, states[0] = -95.098384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353501695, states[0] = 49.345424, states[40]= 0.062763
Saving checkpoint... 
Iteration: 1370939517, states[0] = -95.174427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388271702, states[0] = -95.098039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406748697, states[0] = -95.073961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425270665, states[0] = -95.097049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443846850, states[0] = -95.147022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462218523, states[0] = -95.032621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480971389, states[0] = -95.179527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499636443, states[0] = -51.364521, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1517708616, states[0] = 25.981210, states[40]= 0.071604
Saving checkpoint... 
Iteration: 1530131489, states[0] = -72.416477, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1543499227, states[0] = -95.411010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564625980, states[0] = -65.493789, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1585409327, states[0] = -95.335660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1606033253, states[0] = -78.947620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1626551237, states[0] = -95.389671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647126134, states[0] = -66.562077, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1667439939, states[0] = 13.397785, states[40]= 0.006244
Saving checkpoint... 
Iteration: 1687938716, states[0] = -89.720492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1702559564, states[0] = 3.050055, states[40]= 0.005227
Saving checkpoint... 
Iteration: 1724548612, states[0] = -95.015506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1746442405, states[0] = -93.439065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1768239110, states[0] = 13.784510, states[40]= 0.006304
Saving checkpoint... 
Iteration: 1790063928, states[0] = -95.401970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1811806176, states[0] = -95.162731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833621551, states[0] = -37.896556, states[40]= 0.000185
Saving checkpoint... 
Iteration: 1854878332, states[0] = -95.170336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1878297302, states[0] = -95.124515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1901464138, states[0] = -95.181150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1924526545, states[0] = 20.353005, states[40]= 0.007021
Saving checkpoint... 
Iteration: 1947626828, states[0] = -41.307864, states[40]= 0.000113
Saving checkpoint... 
Iteration: 1970577981, states[0] = 0.182868, states[40]= 0.004287
Saving checkpoint... 
Iteration: 1993550868, states[0] = 12.178405, states[40]= 0.005064
Saving checkpoint... 
Iteration: 2016558457, states[0] = 9.215327, states[40]= 0.004954
Saving checkpoint... 
Iteration: 2039507988, states[0] = 25.153222, states[40]= 0.086060
Saving checkpoint... 
Iteration: 2062498352, states[0] = -95.182496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2085537367, states[0] = 17.069169, states[40]= 0.005556
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.058510
 - CaMKt in component CaMK (millimolar): 0.006979
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.582060
 - nass in component intracellular_ions (millimolar): 6.582120
 - ki in component intracellular_ions (millimolar): 145.396324
 - kss in component intracellular_ions (millimolar): 145.396304
 - cansr in component intracellular_ions (millimolar): 1.311040
 - cajsr in component intracellular_ions (millimolar): 1.272711
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003562
 - hf in component INa (dimensionless): 0.882692
 - hs in component INa (dimensionless): 0.882688
 - j in component INa (dimensionless): 0.882662
 - hsp in component INa (dimensionless): 0.730925
 - jp in component INa (dimensionless): 0.882645
 - mL in component INaL (dimensionless): 0.000048
 - hL in component INaL (dimensionless): 0.713408
 - hLp in component INaL (dimensionless): 0.454858
 - a in component Ito (dimensionless): 0.000617
 - iF in component Ito (dimensionless): 0.999873
 - iS in component Ito (dimensionless): 0.618467
 - ap in component Ito (dimensionless): 0.000314
 - iFp in component Ito (dimensionless): 0.999873
 - iSp in component Ito (dimensionless): 0.692842
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.931340
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999871
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001606
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.342762
 - xs1 in component IKs (dimensionless): 0.249116
 - xs2 in component IKs (dimensionless): 0.000086
 - xk1 in component IK1 (dimensionless): 0.997296
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:30:54 (10688): called boinc_finish(0)

</stderr_txt>
]]>