𝕏

Task 55442618

Name HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_217_1
Workunit 26327512
Created 30 Jun 2024, 12:21:02 UTC
Sent 30 Jun 2024, 13:53:13 UTC
Report deadline 3 Jul 2024, 23:29:13 UTC
Received 1 Jul 2024, 12:48:41 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236597
Run time 2 hours 19 min 27 sec
CPU time 2 hours 16 min 6 sec
Validate state Valid
Credit 62.68
Device peak FLOPS 4.22 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.90 MB
Peak swap size 3.82 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.20.5</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_217.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_217_1_r1563012480_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142054015432_ORdGradInc_k_25-Pueyo_APDR-conf_217_1_r1563012480_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 107.039217
     * GNaL_b in INaL: 0.004915
     * Gto_b in Ito: 0.071548
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.030911
     * GKs_b in IKs: 0.001951
     * GK1_b in IK1: 0.148061
     * Gncx_b in INaCa_i: 0.000959
     * Pnak_b in INaK: 74.014919
     * GKb_b in IKb: 0.003914
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.021704
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 16027450, states[0] = 18.548565, states[40]= 0.007128
Saving checkpoint... 
Iteration: 31930147, states[0] = -94.952120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47798257, states[0] = -94.861662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63574512, states[0] = -1.690295, states[40]= 0.004146
Saving checkpoint... 
Iteration: 79586388, states[0] = -10.481183, states[40]= 0.002310
Saving checkpoint... 
Iteration: 95375096, states[0] = -94.877028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111007944, states[0] = 26.155869, states[40]= 0.083585
Saving checkpoint... 
Iteration: 127222834, states[0] = -94.727183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144937112, states[0] = -94.888904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162738615, states[0] = -94.751515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180737611, states[0] = -94.749367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199354057, states[0] = -94.858288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218072976, states[0] = -0.103245, states[40]= 0.004372
Saving checkpoint... 
Iteration: 237247585, states[0] = -94.763805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255500955, states[0] = 48.548050, states[40]= 0.022828
Saving checkpoint... 
Iteration: 274084785, states[0] = -8.451138, states[40]= 0.002736
Saving checkpoint... 
Iteration: 292936938, states[0] = -94.886606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311360677, states[0] = -94.861009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330234764, states[0] = -94.743916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348411607, states[0] = -94.879985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365916089, states[0] = -94.881251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384285716, states[0] = -94.809143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402977088, states[0] = -94.894202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420989319, states[0] = -94.896007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438465647, states[0] = -94.892279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456475996, states[0] = -94.893998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474901629, states[0] = -94.876863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492645194, states[0] = -69.397796, states[40]= 0.000001
Saving checkpoint... 
Iteration: 510335514, states[0] = -94.847507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529386229, states[0] = -94.871538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548338219, states[0] = -94.849083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567389461, states[0] = -94.872692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587233957, states[0] = -94.742436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604639177, states[0] = -62.312899, states[40]= 0.000003
Saving checkpoint... 
Iteration: 622757341, states[0] = -94.776824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640413027, states[0] = -94.880226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658518295, states[0] = 22.322375, states[40]= 0.012579
Saving checkpoint... 
Iteration: 676601438, states[0] = -24.129492, states[40]= 0.000745
Saving checkpoint... 
Iteration: 694516537, states[0] = 22.779349, states[40]= 0.015639
Saving checkpoint... 
Iteration: 712448447, states[0] = -94.888849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730627848, states[0] = -50.250665, states[40]= 0.000026
Saving checkpoint... 
Iteration: 747848645, states[0] = -94.854754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766571170, states[0] = 0.937169, states[40]= 0.004510
Saving checkpoint... 
Iteration: 784570796, states[0] = 1.145432, states[40]= 0.004536
Saving checkpoint... 
Iteration: 800708641, states[0] = -94.695411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816825237, states[0] = -94.840867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832869969, states[0] = -94.864880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849097512, states[0] = -20.333677, states[40]= 0.000959
Saving checkpoint... 
Iteration: 864755811, states[0] = -94.774674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880568910, states[0] = 2.168495, states[40]= 0.004652
Saving checkpoint... 
Iteration: 896454937, states[0] = -94.890045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912095166, states[0] = -18.062703, states[40]= 0.001144
Saving checkpoint... 
Iteration: 928254114, states[0] = -94.772369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944278690, states[0] = -94.801697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960481610, states[0] = -94.894584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976581255, states[0] = -5.613586, states[40]= 0.003362
Saving checkpoint... 
Iteration: 993276229, states[0] = -94.799050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009441501, states[0] = -94.887202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025395712, states[0] = -94.874609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041198412, states[0] = -94.673476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057327192, states[0] = -94.842012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073725978, states[0] = -94.728499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090418043, states[0] = -94.881381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106417067, states[0] = -94.881103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122686642, states[0] = -94.644300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138462014, states[0] = -94.891237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154656273, states[0] = -85.512757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170691824, states[0] = -94.658246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186707520, states[0] = -94.692880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202824258, states[0] = -94.839999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218608746, states[0] = -31.187120, states[40]= 0.000406
Saving checkpoint... 
Iteration: 1234637059, states[0] = -59.987282, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1250505094, states[0] = 30.673622, states[40]= 0.136034
Saving checkpoint... 
Iteration: 1266606321, states[0] = -28.843609, states[40]= 0.000516
Saving checkpoint... 
Iteration: 1282752269, states[0] = -94.769656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298827121, states[0] = -94.841830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314841675, states[0] = -94.850633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330873138, states[0] = -94.865943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346567572, states[0] = 2.869524, states[40]= 0.004723
Saving checkpoint... 
Iteration: 1362451306, states[0] = -94.889066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378032656, states[0] = 17.824210, states[40]= 0.006270
Saving checkpoint... 
Iteration: 1394137145, states[0] = -60.080479, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1410112625, states[0] = -34.946002, states[40]= 0.000257
Saving checkpoint... 
Iteration: 1425908141, states[0] = -94.878348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441888803, states[0] = -94.871964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457961358, states[0] = -94.890938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473763826, states[0] = -94.784536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489708062, states[0] = -94.693828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1505597533, states[0] = -95.022110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1521415112, states[0] = -55.611675, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1537306150, states[0] = -46.083786, states[40]= 0.000052
Saving checkpoint... 
Iteration: 1552991926, states[0] = -95.051973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1568782242, states[0] = -20.242404, states[40]= 0.001039
Saving checkpoint... 
Iteration: 1584492891, states[0] = -95.063909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600458269, states[0] = -95.169276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1616412916, states[0] = 24.163347, states[40]= 0.030280
Saving checkpoint... 
Iteration: 1632304318, states[0] = 34.265836, states[40]= 0.117900
Saving checkpoint... 
Iteration: 1647918429, states[0] = 22.068100, states[40]= 0.013906
Saving checkpoint... 
Iteration: 1663426626, states[0] = -95.131222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1679154333, states[0] = 4.346846, states[40]= 0.005486
Saving checkpoint... 
Iteration: 1694904895, states[0] = -95.093999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1710890937, states[0] = -95.202183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1727165547, states[0] = -3.515029, states[40]= 0.004240
Saving checkpoint... 
Iteration: 1743300945, states[0] = 48.236145, states[40]= 0.017181
Saving checkpoint... 
Iteration: 1759105776, states[0] = -95.095782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1774909146, states[0] = -50.929063, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1791248688, states[0] = -95.161478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807142079, states[0] = -70.457531, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1822855003, states[0] = -94.896848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1839217658, states[0] = -94.737781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1855684830, states[0] = -94.654116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1871860779, states[0] = -94.869499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1888134000, states[0] = -57.084057, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1903589915, states[0] = -13.209758, states[40]= 0.001788
Saving checkpoint... 
Iteration: 1919504233, states[0] = 33.391033, states[40]= 0.141975
Saving checkpoint... 
Iteration: 1935259902, states[0] = -94.780797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1951383172, states[0] = -94.870442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1967428717, states[0] = -94.884184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1983803152, states[0] = -94.824200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2000188622, states[0] = -94.649736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2016140935, states[0] = -64.302780, states[40]= 0.000002
Saving checkpoint... 
Iteration: 2031767812, states[0] = -94.789035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047813408, states[0] = -94.831887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2063945193, states[0] = -94.887396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2080603940, states[0] = -26.545085, states[40]= 0.000627
Saving checkpoint... 
Iteration: 2096606294, states[0] = -28.817634, states[40]= 0.000517
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.772324
 - CaMKt in component CaMK (millimolar): 0.006740
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.460421
 - nass in component intracellular_ions (millimolar): 6.460479
 - ki in component intracellular_ions (millimolar): 145.519543
 - kss in component intracellular_ions (millimolar): 145.519525
 - cansr in component intracellular_ions (millimolar): 1.304815
 - cajsr in component intracellular_ions (millimolar): 1.267546
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003666
 - hf in component INa (dimensionless): 0.877735
 - hs in component INa (dimensionless): 0.877730
 - j in component INa (dimensionless): 0.877698
 - hsp in component INa (dimensionless): 0.721572
 - jp in component INa (dimensionless): 0.877676
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.706857
 - hLp in component INaL (dimensionless): 0.449197
 - a in component Ito (dimensionless): 0.000629
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.623420
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.698261
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936782
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999891
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001589
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.340285
 - xs1 in component IKs (dimensionless): 0.234881
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997371
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
14:48:27 (95785): called boinc_finish(0)

</stderr_txt>
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