𝕏

Task 55442200

Name HuVeMOp_20240630142040401828_ORdGradInc_k_25-Pueyo_APDR-conf_626_0
Workunit 26327306
Created 30 Jun 2024, 12:20:46 UTC
Sent 30 Jun 2024, 13:50:54 UTC
Report deadline 3 Jul 2024, 23:26:54 UTC
Received 1 Jul 2024, 10:11:10 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237890
Run time 1 hours 28 min 34 sec
CPU time 1 hours 27 min 53 sec
Validate state Valid
Credit 62.96
Device peak FLOPS 4.42 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.63 MB
Peak swap size 6.21 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142040401828_ORdGradInc_k_25-Pueyo_APDR-conf_626.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142040401828_ORdGradInc_k_25-Pueyo_APDR-conf_626_0_r1965319048_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630142040401828_ORdGradInc_k_25-Pueyo_APDR-conf_626_0_r1965319048_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.244066
     * GNaL_b in INaL: 0.006037
     * Gto_b in Ito: 0.073194
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034012
     * GKs_b in IKs: 0.001948
     * GK1_b in IK1: 0.151853
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 68.252336
     * GKb_b in IKb: 0.003927
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033333
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 16840580, states[0] = -94.987726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33864854, states[0] = -94.968031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50590109, states[0] = -15.453318, states[40]= 0.001439
Saving checkpoint... 
Iteration: 67469666, states[0] = -94.970436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84113081, states[0] = -37.945873, states[40]= 0.000164
Saving checkpoint... 
Iteration: 101257952, states[0] = -94.856027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118272251, states[0] = -94.869808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135185559, states[0] = -94.728343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152071501, states[0] = 0.353991, states[40]= 0.004401
Saving checkpoint... 
Iteration: 169165632, states[0] = -94.439455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186125293, states[0] = -50.692226, states[40]= 0.000023
Saving checkpoint... 
Iteration: 203086551, states[0] = -10.932580, states[40]= 0.002200
Saving checkpoint... 
Iteration: 219998769, states[0] = -94.960349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236944493, states[0] = -94.951997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253801623, states[0] = -94.892754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270643519, states[0] = -73.023095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287365690, states[0] = -94.929092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303988326, states[0] = -94.958874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320762604, states[0] = -94.856037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337728349, states[0] = -94.809400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354474540, states[0] = -94.956939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371358849, states[0] = -94.926123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388140515, states[0] = -68.815946, states[40]= 0.000001
Saving checkpoint... 
Iteration: 405183284, states[0] = -94.720577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422188836, states[0] = -94.733733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439295906, states[0] = -94.888082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455867845, states[0] = -94.929848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472763773, states[0] = -94.857264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490191695, states[0] = -94.739977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507337008, states[0] = -94.915405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524212154, states[0] = -94.781186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541231164, states[0] = -94.813742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558128893, states[0] = -54.750111, states[40]= 0.000012
Saving checkpoint... 
Iteration: 575008441, states[0] = 25.326025, states[40]= 0.073891
Saving checkpoint... 
Iteration: 591916822, states[0] = -94.945524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608817034, states[0] = -94.903431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625711090, states[0] = -94.779137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642916985, states[0] = -94.945537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659806914, states[0] = -94.896409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676706334, states[0] = -94.769991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693808178, states[0] = -94.897302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710769703, states[0] = -94.863597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727508365, states[0] = 25.379422, states[40]= 0.075137
Saving checkpoint... 
Iteration: 744747607, states[0] = -94.837347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761797987, states[0] = -94.889570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778688437, states[0] = -94.732636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795671670, states[0] = -94.653902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812560862, states[0] = 5.948519, states[40]= 0.004913
Saving checkpoint... 
Iteration: 829710689, states[0] = -94.778266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846687138, states[0] = -94.729648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863810765, states[0] = -94.899038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880501838, states[0] = 46.458050, states[40]= 0.076122
Saving checkpoint... 
Iteration: 897854284, states[0] = -94.923782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914861669, states[0] = -94.927033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931821457, states[0] = -94.906092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948658267, states[0] = -92.686842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965881166, states[0] = -94.934589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983014769, states[0] = 23.018124, states[40]= 0.020043
Saving checkpoint... 
Iteration: 1001486823, states[0] = -94.958273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019353081, states[0] = -94.923160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037750270, states[0] = -94.840665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055970738, states[0] = -94.955973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074160303, states[0] = -93.533040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092549997, states[0] = 10.818817, states[40]= 0.005167
Saving checkpoint... 
Iteration: 1110450632, states[0] = -94.952569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128738172, states[0] = -94.823999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146580473, states[0] = -5.685611, states[40]= 0.003327
Saving checkpoint... 
Iteration: 1165035636, states[0] = 16.645951, states[40]= 0.005842
Saving checkpoint... 
Iteration: 1183269743, states[0] = -94.863372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201440805, states[0] = -94.950620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219513407, states[0] = 23.358444, states[40]= 0.025582
Saving checkpoint... 
Iteration: 1237408660, states[0] = -94.943013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255635876, states[0] = -62.925716, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1273802745, states[0] = -94.892971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291978598, states[0] = -94.956993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310019676, states[0] = 21.811793, states[40]= 0.010701
Saving checkpoint... 
Iteration: 1327909551, states[0] = -94.943205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345983151, states[0] = -94.957592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363925566, states[0] = -94.947216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382399290, states[0] = -94.940254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400632348, states[0] = -58.735763, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1418902912, states[0] = -94.941296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437034511, states[0] = 17.068585, states[40]= 0.005945
Saving checkpoint... 
Iteration: 1455071505, states[0] = 0.382842, states[40]= 0.004403
Saving checkpoint... 
Iteration: 1473435886, states[0] = -94.949449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491369646, states[0] = -94.929982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1509485728, states[0] = -95.067828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1527627579, states[0] = 18.442740, states[40]= 0.008024
Saving checkpoint... 
Iteration: 1545458716, states[0] = -95.030459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1563993160, states[0] = -34.410113, states[40]= 0.000267
Saving checkpoint... 
Iteration: 1581748315, states[0] = -94.948895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1599847163, states[0] = -95.217451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1618378323, states[0] = -95.102731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636582779, states[0] = -22.967365, states[40]= 0.000820
Saving checkpoint... 
Iteration: 1654774517, states[0] = -95.247100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1672783028, states[0] = -95.254197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1690731087, states[0] = -95.200812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1708912779, states[0] = -59.082730, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1727078995, states[0] = -95.251262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1745208135, states[0] = -53.115775, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1763190709, states[0] = -32.129147, states[40]= 0.000351
Saving checkpoint... 
Iteration: 1781198564, states[0] = -41.275769, states[40]= 0.000105
Saving checkpoint... 
Iteration: 1799153116, states[0] = 4.612614, states[40]= 0.005477
Saving checkpoint... 
Iteration: 1817308708, states[0] = -94.943439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1835246189, states[0] = -94.863442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1853495541, states[0] = -94.975511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1871468962, states[0] = -94.965035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1889608424, states[0] = -33.019852, states[40]= 0.000314
Saving checkpoint... 
Iteration: 1907911083, states[0] = -94.946639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1925948371, states[0] = -94.953649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1944217227, states[0] = -94.790790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1962522964, states[0] = 20.909074, states[40]= 0.008448
Saving checkpoint... 
Iteration: 1980286372, states[0] = -94.879465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1998810218, states[0] = -94.898208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2016692052, states[0] = -94.739977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035113522, states[0] = -37.917399, states[40]= 0.000164
Saving checkpoint... 
Iteration: 2052970367, states[0] = -94.955355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2071449618, states[0] = -94.951819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2088995131, states[0] = -94.958669, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.835106
 - CaMKt in component CaMK (millimolar): 0.006647
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.638182
 - nass in component intracellular_ions (millimolar): 6.638241
 - ki in component intracellular_ions (millimolar): 145.343255
 - kss in component intracellular_ions (millimolar): 145.343236
 - cansr in component intracellular_ions (millimolar): 1.297565
 - cajsr in component intracellular_ions (millimolar): 1.260595
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003643
 - hf in component INa (dimensionless): 0.878838
 - hs in component INa (dimensionless): 0.878833
 - j in component INa (dimensionless): 0.878804
 - hsp in component INa (dimensionless): 0.723643
 - jp in component INa (dimensionless): 0.878785
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709602
 - hLp in component INaL (dimensionless): 0.454383
 - a in component Ito (dimensionless): 0.000626
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.627356
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.703054
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937842
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999897
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001552
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330989
 - xs1 in component IKs (dimensionless): 0.232444
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997355
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:05:56 (10208): called boinc_finish(0)

</stderr_txt>
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