𝕏

Task 55441956

Name HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_192_0
Workunit 26327198
Created 30 Jun 2024, 12:11:18 UTC
Sent 30 Jun 2024, 13:48:22 UTC
Report deadline 3 Jul 2024, 23:24:22 UTC
Received 1 Jul 2024, 22:47:42 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227663
Run time 3 hours 7 min 48 sec
CPU time 2 hours 20 min 24 sec
Validate state Valid
Credit 60.81
Device peak FLOPS 2.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.92 MB
Peak swap size 32.57 GB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_192.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_192_0_r860570133_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_192_0_r860570133_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 99.890823
     * GNaL_b in INaL: 0.006466
     * Gto_b in Ito: 0.096794
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030787
     * GKs_b in IKs: 0.002107
     * GK1_b in IK1: 0.163490
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 67.536963
     * GKb_b in IKb: 0.003845
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037369
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 18835602, states[0] = -94.950807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36992502, states[0] = -94.975097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55078160, states[0] = 0.287319, states[40]= 0.004162
Saving checkpoint... 
Iteration: 79132688, states[0] = -44.823176, states[40]= 0.000067
Saving checkpoint... 
Iteration: 106295268, states[0] = -94.878880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130258838, states[0] = -94.839532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148245845, states[0] = -94.821628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166020214, states[0] = 20.739420, states[40]= 0.008582
Saving checkpoint... 
Iteration: 185373595, states[0] = -94.922654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202670105, states[0] = -91.214439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216316283, states[0] = -94.892093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231542221, states[0] = 15.072489, states[40]= 0.004809
Saving checkpoint... 
Iteration: 248403908, states[0] = -94.932803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265733677, states[0] = -94.802344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282787996, states[0] = -94.869266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299952506, states[0] = -94.944340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318337934, states[0] = -94.905406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336426367, states[0] = -94.938720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357627834, states[0] = -39.733451, states[40]= 0.000143
Saving checkpoint... 
Iteration: 380911264, states[0] = -94.934774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401603871, states[0] = -18.337083, states[40]= 0.001087
Saving checkpoint... 
Iteration: 419619118, states[0] = -31.800811, states[40]= 0.000411
Saving checkpoint... 
Iteration: 439212227, states[0] = -94.764461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460766938, states[0] = -94.847444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486976719, states[0] = -94.948275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504705767, states[0] = -94.751736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519546997, states[0] = 13.456237, states[40]= 0.004732
Saving checkpoint... 
Iteration: 533648398, states[0] = -60.784389, states[40]= 0.000005
Saving checkpoint... 
Iteration: 545498182, states[0] = -94.951144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560895715, states[0] = -94.929991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575876620, states[0] = -94.923254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589952137, states[0] = -94.944046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605109137, states[0] = -22.982630, states[40]= 0.000830
Saving checkpoint... 
Iteration: 619389288, states[0] = -94.927818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634453155, states[0] = -94.944204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648879748, states[0] = -94.924387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662042063, states[0] = 15.125905, states[40]= 0.004813
Saving checkpoint... 
Iteration: 676783091, states[0] = -94.864318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690168333, states[0] = -89.315936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703088493, states[0] = -5.622176, states[40]= 0.003167
Saving checkpoint... 
Iteration: 716186193, states[0] = -94.684159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728999063, states[0] = -94.951115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741209707, states[0] = -94.759361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755412032, states[0] = -94.934708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770153240, states[0] = -66.482346, states[40]= 0.000002
Saving checkpoint... 
Iteration: 787959415, states[0] = -94.945230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804279029, states[0] = -94.860201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823251524, states[0] = -94.828065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845543189, states[0] = 14.751634, states[40]= 0.004788
Saving checkpoint... 
Iteration: 864351105, states[0] = -94.911909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885091009, states[0] = -7.465994, states[40]= 0.002784
Saving checkpoint... 
Iteration: 905202207, states[0] = -94.744158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922930884, states[0] = -94.939347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942130386, states[0] = -42.153056, states[40]= 0.000100
Saving checkpoint... 
Iteration: 958683924, states[0] = -94.651202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977269988, states[0] = -94.850496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993548242, states[0] = 13.024825, states[40]= 0.004720
Saving checkpoint... 
Iteration: 1008448579, states[0] = -94.943050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021678888, states[0] = -94.431103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036550752, states[0] = 12.143184, states[40]= 0.004705
Saving checkpoint... 
Iteration: 1050116920, states[0] = -29.846201, states[40]= 0.000507
Saving checkpoint... 
Iteration: 1065151829, states[0] = -64.755571, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1078422161, states[0] = -94.937132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094745883, states[0] = -94.820086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106809876, states[0] = -94.886728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119019321, states[0] = 20.866852, states[40]= 0.009347
Saving checkpoint... 
Iteration: 1130040934, states[0] = 15.496538, states[40]= 0.004842
Saving checkpoint... 
Iteration: 1142675311, states[0] = -93.896792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147840637, states[0] = -94.906276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153176037, states[0] = -94.054397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155071812, states[0] = 3.781861, states[40]= 0.004474
Saving checkpoint... 
Iteration: 1157064907, states[0] = 6.775843, states[40]= 0.004620
Saving checkpoint... 
Iteration: 1170079339, states[0] = 0.039863, states[40]= 0.004120
Saving checkpoint... 
Iteration: 1177498083, states[0] = -94.950663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185720239, states[0] = -94.778796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196497990, states[0] = -94.950638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203740654, states[0] = -94.812395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210100790, states[0] = -15.616681, states[40]= 0.001353
Saving checkpoint... 
Iteration: 1220547022, states[0] = 13.447763, states[40]= 0.004731
Saving checkpoint... 
Iteration: 1233626329, states[0] = -38.331344, states[40]= 0.000175
Saving checkpoint... 
Iteration: 1246058255, states[0] = 9.397345, states[40]= 0.004676
Saving checkpoint... 
Iteration: 1258705972, states[0] = -94.751583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272065056, states[0] = 6.714564, states[40]= 0.004618
Saving checkpoint... 
Iteration: 1283471246, states[0] = -94.946842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297728432, states[0] = -94.792960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311343098, states[0] = -94.907480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326010824, states[0] = 21.651151, states[40]= 0.042432
Saving checkpoint... 
Iteration: 1336880491, states[0] = -94.924153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351224630, states[0] = -94.786435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365107749, states[0] = -21.760177, states[40]= 0.000884
Saving checkpoint... 
Iteration: 1378569994, states[0] = 4.603431, states[40]= 0.004524
Saving checkpoint... 
Iteration: 1391783055, states[0] = -94.863751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401912486, states[0] = -94.934353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412800297, states[0] = -94.879071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425099327, states[0] = -14.334397, states[40]= 0.001520
Saving checkpoint... 
Iteration: 1436708139, states[0] = -94.755763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450080517, states[0] = -0.608121, states[40]= 0.004036
Saving checkpoint... 
Iteration: 1461550980, states[0] = 12.062380, states[40]= 0.004704
Saving checkpoint... 
Iteration: 1474359639, states[0] = -94.915486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487422230, states[0] = -94.936846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1500539529, states[0] = -95.096119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1513966526, states[0] = -94.980869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1526849087, states[0] = -93.282044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1539683941, states[0] = -15.837063, states[40]= 0.001496
Saving checkpoint... 
Iteration: 1548072198, states[0] = -5.002597, states[40]= 0.003745
Saving checkpoint... 
Iteration: 1559724194, states[0] = 19.331843, states[40]= 0.007777
Saving checkpoint... 
Iteration: 1570654291, states[0] = -94.785604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581950490, states[0] = 8.121887, states[40]= 0.005398
Saving checkpoint... 
Iteration: 1595065740, states[0] = -95.199765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1607087505, states[0] = -95.219396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1619944247, states[0] = -95.178611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1632917235, states[0] = 21.061985, states[40]= 0.013446
Saving checkpoint... 
Iteration: 1645842792, states[0] = 11.759858, states[40]= 0.005633
Saving checkpoint... 
Iteration: 1660780582, states[0] = -95.215940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1675049776, states[0] = -94.244617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1689058656, states[0] = 3.669549, states[40]= 0.005107
Saving checkpoint... 
Iteration: 1703996348, states[0] = -95.227970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1717745527, states[0] = -95.181592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1733137651, states[0] = 14.066965, states[40]= 0.005869
Saving checkpoint... 
Iteration: 1747923026, states[0] = -59.191310, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1762503888, states[0] = 31.242814, states[40]= 0.146119
Saving checkpoint... 
Iteration: 1777048212, states[0] = -93.784145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1791603248, states[0] = 34.492439, states[40]= 0.134576
Saving checkpoint... 
Iteration: 1806054344, states[0] = 9.852229, states[40]= 0.004739
Saving checkpoint... 
Iteration: 1819329117, states[0] = -94.938473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833541670, states[0] = 14.878359, states[40]= 0.004820
Saving checkpoint... 
Iteration: 1847667396, states[0] = -89.765746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1862482438, states[0] = -94.959313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1878929141, states[0] = -94.945088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1892011616, states[0] = 21.533671, states[40]= 0.035101
Saving checkpoint... 
Iteration: 1904283834, states[0] = -94.867358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1918291068, states[0] = -94.872933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1929586986, states[0] = -4.637683, states[40]= 0.003364
Saving checkpoint... 
Iteration: 1942762556, states[0] = -94.842204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1957137469, states[0] = -49.225917, states[40]= 0.000034
Saving checkpoint... 
Iteration: 1971616792, states[0] = -29.757057, states[40]= 0.000512


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_192.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_192_0_r860570133_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_192_0_r860570133_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 99.890823
     * GNaL_b in INaL: 0.006466
     * Gto_b in Ito: 0.096794
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030787
     * GKs_b in IKs: 0.002107
     * GK1_b in IK1: 0.163490
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 67.536963
     * GKb_b in IKb: 0.003845
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037369
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1971616792
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -29.757057 (After loading)
 - states[40]: 0.000512 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading resultsTime...
Loading resultsAPD90...
Loading resultsAPD75...
Loading resultsAPD50...
Loading resultsAPD25...
Loading resultsAPD10...
Loading resultsTriangulation...
Loading resultsMaxV...
Loading resultsMinV...
Loading resultsMaxDiffV...
Loading resultsMinDiffV...
Copy resultsTime...
Copy resultsAPD90...
Copy resultsAPD75...
Copy resultsAPD50...
Copy resultsAPD25...
Copy resultsAPD10...
Copy resultsTriangulation...
Copy resultsMaxV...
Copy resultsMinV...
Copy resultsMaxDiffV...
Copy resultsMinDiffV...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1981044012, states[0] = 14.470502, states[40]= 0.004772
Saving checkpoint... 
Iteration: 1994795819, states[0] = -94.875065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2009923389, states[0] = -94.936819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2024091358, states[0] = -7.735467, states[40]= 0.002728
Saving checkpoint... 
Iteration: 2038007465, states[0] = 22.727752, states[40]= 0.096954
Saving checkpoint... 
Iteration: 2052403278, states[0] = -94.931199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067503595, states[0] = 31.287455, states[40]= 0.167635
Saving checkpoint... 
Iteration: 2082259215, states[0] = -94.836981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2095380297, states[0] = -94.923456, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.826025
 - CaMKt in component CaMK (millimolar): 0.007304
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.709195
 - nass in component intracellular_ions (millimolar): 6.709255
 - ki in component intracellular_ions (millimolar): 145.264975
 - kss in component intracellular_ions (millimolar): 145.264956
 - cansr in component intracellular_ions (millimolar): 1.322756
 - cajsr in component intracellular_ions (millimolar): 1.283764
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003646
 - hf in component INa (dimensionless): 0.878679
 - hs in component INa (dimensionless): 0.878674
 - j in component INa (dimensionless): 0.878644
 - hsp in component INa (dimensionless): 0.723343
 - jp in component INa (dimensionless): 0.878623
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.706001
 - hLp in component INaL (dimensionless): 0.444185
 - a in component Ito (dimensionless): 0.000627
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.613081
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.686639
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.932430
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999872
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001626
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329763
 - xs1 in component IKs (dimensionless): 0.251236
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997357
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:47:22 (48000): called boinc_finish(0)

</stderr_txt>
]]>


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