𝕏

Task 55441838

Name HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_948_0
Workunit 26327139
Created 30 Jun 2024, 12:11:12 UTC
Sent 30 Jun 2024, 13:49:05 UTC
Report deadline 3 Jul 2024, 23:25:05 UTC
Received 30 Jun 2024, 22:28:17 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 47 min 26 sec
CPU time 1 hours 44 min 5 sec
Validate state Valid
Credit 57.40
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.09 MB
Peak swap size 4.13 GB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_948.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_948_0_r2100768919_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_948_0_r2100768919_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 118.973231
     * GNaL_b in INaL: 0.004969
     * Gto_b in Ito: 0.071553
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.030153
     * GKs_b in IKs: 0.001857
     * GK1_b in IK1: 0.159371
     * Gncx_b in INaCa_i: 0.000956
     * Pnak_b in INaK: 73.563788
     * GKb_b in IKb: 0.003765
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.050432
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12383716, states[0] = -95.119980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23576233, states[0] = -4.244185, states[40]= 0.003661
Saving checkpoint... 
Iteration: 35602527, states[0] = -27.506556, states[40]= 0.000557
Saving checkpoint... 
Iteration: 47851538, states[0] = -95.024439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60405045, states[0] = -95.030207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72855331, states[0] = -95.006141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84942413, states[0] = -95.025026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96970289, states[0] = -95.025781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109301016, states[0] = -94.965346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120810540, states[0] = -94.969944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133224012, states[0] = -94.880961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145232844, states[0] = -94.892900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156376914, states[0] = -94.998065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167994579, states[0] = -95.021281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180632654, states[0] = -54.794882, states[40]= 0.000011
Saving checkpoint... 
Iteration: 193668202, states[0] = -94.471354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207278383, states[0] = -94.941935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219495809, states[0] = -95.020564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231658771, states[0] = -90.289462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245180262, states[0] = -94.792404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258742078, states[0] = -94.903094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271521065, states[0] = 21.744702, states[40]= 0.010413
Saving checkpoint... 
Iteration: 285579828, states[0] = -3.896775, states[40]= 0.003675
Saving checkpoint... 
Iteration: 299312913, states[0] = -94.967104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313415091, states[0] = -95.007171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327381404, states[0] = -94.997961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341235791, states[0] = -94.894738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353919727, states[0] = -95.008194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367094843, states[0] = -16.794835, states[40]= 0.001258
Saving checkpoint... 
Iteration: 381196164, states[0] = -94.830261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395379707, states[0] = -94.997376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410282463, states[0] = -94.945000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426821637, states[0] = -94.972191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442659469, states[0] = -90.979880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458837313, states[0] = -94.980417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474564609, states[0] = 4.711413, states[40]= 0.004843
Saving checkpoint... 
Iteration: 491910142, states[0] = -95.005896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508147270, states[0] = -72.482804, states[40]= 0.000001
Saving checkpoint... 
Iteration: 524511494, states[0] = 24.527359, states[40]= 0.039985
Saving checkpoint... 
Iteration: 540944263, states[0] = -95.012973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556905558, states[0] = -95.004727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573559290, states[0] = 7.164282, states[40]= 0.005012
Saving checkpoint... 
Iteration: 590207221, states[0] = -94.850277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606712104, states[0] = -94.858653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623199966, states[0] = -94.837234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639390291, states[0] = -95.000521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656271256, states[0] = -94.934901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673081088, states[0] = -4.790946, states[40]= 0.003494
Saving checkpoint... 
Iteration: 688846041, states[0] = -94.984380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704953275, states[0] = -95.014422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720454479, states[0] = -95.014609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736868780, states[0] = -94.993485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753303122, states[0] = -94.960506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770145498, states[0] = -69.973318, states[40]= 0.000001
Saving checkpoint... 
Iteration: 786338517, states[0] = -94.980846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803450261, states[0] = -95.013880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819691397, states[0] = -94.820844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837359436, states[0] = -94.989927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853957894, states[0] = -95.015086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870912467, states[0] = -95.006278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887108550, states[0] = -30.094785, states[40]= 0.000441
Saving checkpoint... 
Iteration: 903811098, states[0] = -94.965665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921300655, states[0] = -94.958724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938045631, states[0] = 12.959117, states[40]= 0.005417
Saving checkpoint... 
Iteration: 955111156, states[0] = -32.635744, states[40]= 0.000330
Saving checkpoint... 
Iteration: 972271471, states[0] = -94.934955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988198147, states[0] = -94.833693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009807805, states[0] = -94.963506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031077658, states[0] = -2.438203, states[40]= 0.003950
Saving checkpoint... 
Iteration: 1051973379, states[0] = -95.017230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068418983, states[0] = -95.007689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084685942, states[0] = -94.809159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101604571, states[0] = -26.227208, states[40]= 0.000626
Saving checkpoint... 
Iteration: 1119321299, states[0] = -94.971673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136900663, states[0] = -95.003184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153588493, states[0] = -10.831681, states[40]= 0.002202
Saving checkpoint... 
Iteration: 1170219226, states[0] = -94.870027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187227059, states[0] = -94.881994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203896861, states[0] = -95.002124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221899342, states[0] = -95.002791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238743239, states[0] = -94.904022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255276966, states[0] = -94.939848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272889421, states[0] = -94.999969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290214950, states[0] = -94.863067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306106475, states[0] = -28.076268, states[40]= 0.000536
Saving checkpoint... 
Iteration: 1322617642, states[0] = -39.029131, states[40]= 0.000139
Saving checkpoint... 
Iteration: 1339416684, states[0] = -95.007042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356014939, states[0] = 23.422070, states[40]= 0.021211
Saving checkpoint... 
Iteration: 1373174482, states[0] = -94.742982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390035703, states[0] = 16.871323, states[40]= 0.006091
Saving checkpoint... 
Iteration: 1406394456, states[0] = -95.001359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422216622, states[0] = -94.865735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439384576, states[0] = -94.998426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456644010, states[0] = -67.980289, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1473118615, states[0] = -40.003856, states[40]= 0.000121
Saving checkpoint... 
Iteration: 1489629851, states[0] = -51.705027, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1504739895, states[0] = -95.205615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1521195116, states[0] = -95.158781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1538682708, states[0] = -95.275423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1556070604, states[0] = -95.275302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1572684208, states[0] = -21.549595, states[40]= 0.000920
Saving checkpoint... 
Iteration: 1589867428, states[0] = -95.132544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1606718065, states[0] = -95.228888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1623966293, states[0] = -3.500579, states[40]= 0.004199
Saving checkpoint... 
Iteration: 1640557850, states[0] = -95.105490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1656365960, states[0] = -3.259442, states[40]= 0.004251
Saving checkpoint... 
Iteration: 1672749513, states[0] = -95.268383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1689113520, states[0] = -55.484503, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1705606081, states[0] = -46.548784, states[40]= 0.000047
Saving checkpoint... 
Iteration: 1722390625, states[0] = -29.066053, states[40]= 0.000487
Saving checkpoint... 
Iteration: 1738953969, states[0] = -95.078384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1754713867, states[0] = 24.099378, states[40]= 0.026985
Saving checkpoint... 
Iteration: 1771598141, states[0] = -37.436852, states[40]= 0.000178
Saving checkpoint... 
Iteration: 1788386972, states[0] = -25.007019, states[40]= 0.000698
Saving checkpoint... 
Iteration: 1804582386, states[0] = -8.646700, states[40]= 0.002755
Saving checkpoint... 
Iteration: 1821319757, states[0] = -95.006479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1838208499, states[0] = -94.874612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1855080233, states[0] = -4.712649, states[40]= 0.003523
Saving checkpoint... 
Iteration: 1870658757, states[0] = -90.960369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1888754719, states[0] = -94.922422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1906882546, states[0] = -95.000497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1924147653, states[0] = -73.253004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1941682014, states[0] = -94.799188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1959407645, states[0] = -95.005196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1976852492, states[0] = -94.986919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1995470514, states[0] = -95.016586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2013819813, states[0] = -94.970497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2031185964, states[0] = -94.808808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047964819, states[0] = -95.015580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2064412535, states[0] = -95.005729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2081317628, states[0] = -94.969076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098248378, states[0] = -94.909883, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.895742
 - CaMKt in component CaMK (millimolar): 0.006413
 - cass in component intracellular_ions (millimolar): 0.000072
 - nai in component intracellular_ions (millimolar): 6.443225
 - nass in component intracellular_ions (millimolar): 6.443281
 - ki in component intracellular_ions (millimolar): 145.543146
 - kss in component intracellular_ions (millimolar): 145.543127
 - cansr in component intracellular_ions (millimolar): 1.279386
 - cajsr in component intracellular_ions (millimolar): 1.242376
 - cai in component intracellular_ions (millimolar): 0.000073
 - m in component INa (dimensionless): 0.003621
 - hf in component INa (dimensionless): 0.879895
 - hs in component INa (dimensionless): 0.879891
 - j in component INa (dimensionless): 0.879865
 - hsp in component INa (dimensionless): 0.725633
 - jp in component INa (dimensionless): 0.879847
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710372
 - hLp in component INaL (dimensionless): 0.453600
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.624006
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.698957
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935810
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999887
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001491
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.343977
 - xs1 in component IKs (dimensionless): 0.237111
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997339
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:28:06 (99775): called boinc_finish(0)

</stderr_txt>
]]>


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