𝕏

Task 55441678

Name HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_626_0
Workunit 26327059
Created 30 Jun 2024, 12:11:07 UTC
Sent 30 Jun 2024, 13:48:22 UTC
Report deadline 3 Jul 2024, 23:24:22 UTC
Received 1 Jul 2024, 23:05:32 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227663
Run time 3 hours 9 min 30 sec
CPU time 2 hours 23 min 30 sec
Validate state Valid
Credit 60.91
Device peak FLOPS 2.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.85 MB
Peak swap size 32.57 GB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_626.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_626_0_r885242107_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_626_0_r885242107_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.244066
     * GNaL_b in INaL: 0.006037
     * Gto_b in Ito: 0.073194
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034012
     * GKs_b in IKs: 0.001948
     * GK1_b in IK1: 0.151853
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 68.252336
     * GKb_b in IKb: 0.003927
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033333
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 17166354, states[0] = -94.700447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31821856, states[0] = -94.948894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48961189, states[0] = -94.979483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65629411, states[0] = -56.343054, states[40]= 0.000009
Saving checkpoint... 
Iteration: 84374159, states[0] = -94.941081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101725471, states[0] = -94.810099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119535382, states[0] = 16.705195, states[40]= 0.005864
Saving checkpoint... 
Iteration: 138227864, states[0] = -94.810543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157269351, states[0] = -94.864573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179167681, states[0] = -94.553363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204738104, states[0] = -94.824686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224622134, states[0] = -47.140898, states[40]= 0.000041
Saving checkpoint... 
Iteration: 242945293, states[0] = -94.952133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261479917, states[0] = -94.957808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285321719, states[0] = -94.906647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310083573, states[0] = -8.242863, states[40]= 0.002768
Saving checkpoint... 
Iteration: 324985066, states[0] = -94.958430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338864312, states[0] = -94.928475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353590809, states[0] = -15.020862, states[40]= 0.001493
Saving checkpoint... 
Iteration: 365910850, states[0] = -94.944099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381013776, states[0] = 23.263841, states[40]= 0.023877
Saving checkpoint... 
Iteration: 395112658, states[0] = -37.022025, states[40]= 0.000186
Saving checkpoint... 
Iteration: 408468459, states[0] = -94.955987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422297166, states[0] = -94.889107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436882122, states[0] = -94.935224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451905357, states[0] = -94.942538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467424300, states[0] = -94.947423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482249454, states[0] = -94.839922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496617670, states[0] = -42.271523, states[40]= 0.000087
Saving checkpoint... 
Iteration: 509925451, states[0] = -94.947670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523280881, states[0] = -94.874878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536632126, states[0] = -58.477731, states[40]= 0.000006
Saving checkpoint... 
Iteration: 549576068, states[0] = -2.482529, states[40]= 0.003961
Saving checkpoint... 
Iteration: 561561366, states[0] = 5.707990, states[40]= 0.004898
Saving checkpoint... 
Iteration: 576173601, states[0] = -94.676627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591073047, states[0] = -0.542049, states[40]= 0.004275
Saving checkpoint... 
Iteration: 609134431, states[0] = -61.189737, states[40]= 0.000004
Saving checkpoint... 
Iteration: 627434393, states[0] = -94.949607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645819732, states[0] = -94.905159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667549539, states[0] = 11.014107, states[40]= 0.005178
Saving checkpoint... 
Iteration: 685368293, states[0] = -94.929898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706623165, states[0] = -48.277097, states[40]= 0.000035
Saving checkpoint... 
Iteration: 725675390, states[0] = -94.690299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743653827, states[0] = -88.882224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758526458, states[0] = 19.859765, states[40]= 0.007225
Saving checkpoint... 
Iteration: 776941796, states[0] = -94.951058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792182402, states[0] = -94.718018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809765262, states[0] = -94.858734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823330527, states[0] = -94.911612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838196495, states[0] = -94.749991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852264113, states[0] = -94.857431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868024092, states[0] = 20.585991, states[40]= 0.007968
Saving checkpoint... 
Iteration: 881219918, states[0] = -94.794976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899155372, states[0] = -90.565382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911585549, states[0] = -9.997278, states[40]= 0.002391
Saving checkpoint... 
Iteration: 923224764, states[0] = -94.803200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936044204, states[0] = 13.246327, states[40]= 0.005340
Saving checkpoint... 
Iteration: 947448944, states[0] = -94.952347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957794625, states[0] = -94.886744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962228573, states[0] = -94.809400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966530488, states[0] = 18.519114, states[40]= 0.006432
Saving checkpoint... 
Iteration: 968365000, states[0] = -94.928401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975062648, states[0] = 5.088470, states[40]= 0.004858
Saving checkpoint... 
Iteration: 989280221, states[0] = -94.873990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994167586, states[0] = -94.546851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003723131, states[0] = -94.800416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013614256, states[0] = -38.674456, states[40]= 0.000148
Saving checkpoint... 
Iteration: 1020925299, states[0] = -94.947347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027982880, states[0] = -94.957734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040386999, states[0] = -94.936557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052954466, states[0] = -94.953295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065254115, states[0] = -94.845517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078130340, states[0] = -56.409832, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1090689087, states[0] = -94.733913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104009307, states[0] = 24.800472, states[40]= 0.060943
Saving checkpoint... 
Iteration: 1117012710, states[0] = 23.544223, states[40]= 0.029296
Saving checkpoint... 
Iteration: 1130164731, states[0] = -94.358542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141775520, states[0] = -94.869328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153970880, states[0] = -94.955939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167513517, states[0] = 23.330040, states[40]= 0.025056
Saving checkpoint... 
Iteration: 1180659695, states[0] = -93.323484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194481056, states[0] = -94.957391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205690952, states[0] = -94.737955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216886905, states[0] = -94.936426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228763144, states[0] = -94.856127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241717600, states[0] = -94.790694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254285882, states[0] = -94.879068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267542986, states[0] = 13.745241, states[40]= 0.005388
Saving checkpoint... 
Iteration: 1278841600, states[0] = -94.917397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291734931, states[0] = -94.819101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303425108, states[0] = -94.947143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316602157, states[0] = -26.388861, states[40]= 0.000609
Saving checkpoint... 
Iteration: 1329873414, states[0] = -94.931535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342579910, states[0] = -5.248538, states[40]= 0.003420
Saving checkpoint... 
Iteration: 1353758065, states[0] = -94.850158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364462926, states[0] = -94.954565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377087878, states[0] = -12.170413, states[40]= 0.001961
Saving checkpoint... 
Iteration: 1389298892, states[0] = -94.889931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400922070, states[0] = -94.946366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414304817, states[0] = -94.894444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427359626, states[0] = -94.925866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440240507, states[0] = -94.827189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453216394, states[0] = -94.788419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467849438, states[0] = -94.921192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482662184, states[0] = -94.004682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497186314, states[0] = -94.727370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1511881998, states[0] = -95.061905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1527372528, states[0] = -9.921192, states[40]= 0.002688
Saving checkpoint... 
Iteration: 1542059416, states[0] = 0.943954, states[40]= 0.005009
Saving checkpoint... 
Iteration: 1556693758, states[0] = -95.248483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1571112127, states[0] = 24.116861, states[40]= 0.034289
Saving checkpoint... 
Iteration: 1586066389, states[0] = -95.235141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600935628, states[0] = -92.224116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1615587078, states[0] = -27.862629, states[40]= 0.000543
Saving checkpoint... 
Iteration: 1629514024, states[0] = -95.174325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1642624332, states[0] = -75.738702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1657445195, states[0] = -95.218120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1672792893, states[0] = -95.261403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1688704198, states[0] = 33.790844, states[40]= 0.120653
Saving checkpoint... 
Iteration: 1701688734, states[0] = -29.856221, states[40]= 0.000448
Saving checkpoint... 
Iteration: 1715478587, states[0] = -18.175752, states[40]= 0.001239
Saving checkpoint... 
Iteration: 1729915656, states[0] = -62.894704, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1742718289, states[0] = 21.804173, states[40]= 0.013712
Saving checkpoint... 
Iteration: 1755240498, states[0] = -95.212999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1768289593, states[0] = -30.847660, states[40]= 0.000404
Saving checkpoint... 
Iteration: 1782377147, states[0] = -16.522254, states[40]= 0.001450
Saving checkpoint... 
Iteration: 1797396613, states[0] = -38.967787, states[40]= 0.000146


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_626.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_626_0_r885242107_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_626_0_r885242107_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.244066
     * GNaL_b in INaL: 0.006037
     * Gto_b in Ito: 0.073194
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034012
     * GKs_b in IKs: 0.001948
     * GK1_b in IK1: 0.151853
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 68.252336
     * GKb_b in IKb: 0.003927
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033333
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1797396613
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -38.967787 (After loading)
 - states[40]: 0.000146 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading resultsTime...
Loading resultsAPD90...
Loading resultsAPD75...
Loading resultsAPD50...
Loading resultsAPD25...
Loading resultsAPD10...
Loading resultsTriangulation...
Loading resultsMaxV...
Loading resultsMinV...
Loading resultsMaxDiffV...
Loading resultsMinDiffV...
Copy resultsTime...
Copy resultsAPD90...
Copy resultsAPD75...
Copy resultsAPD50...
Copy resultsAPD25...
Copy resultsAPD10...
Copy resultsTriangulation...
Copy resultsMaxV...
Copy resultsMinV...
Copy resultsMaxDiffV...
Copy resultsMinDiffV...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1806717893, states[0] = -94.845908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1820532214, states[0] = 17.430938, states[40]= 0.006161
Saving checkpoint... 
Iteration: 1835575449, states[0] = -2.933994, states[40]= 0.003904
Saving checkpoint... 
Iteration: 1848876976, states[0] = -94.951621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1863816361, states[0] = -94.914600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1878778997, states[0] = -94.880293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1893500773, states[0] = 43.976451, states[40]= 0.011010
Saving checkpoint... 
Iteration: 1908758774, states[0] = -94.853997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1924269005, states[0] = -94.864256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1939614025, states[0] = -38.511353, states[40]= 0.000151
Saving checkpoint... 
Iteration: 1955121550, states[0] = -46.539116, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1969877222, states[0] = -94.933112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1983802693, states[0] = -94.892857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1998246671, states[0] = -94.835590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2011870340, states[0] = -94.930078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2027220011, states[0] = -94.794546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2042269091, states[0] = -94.862214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2057451038, states[0] = -94.952104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2072323720, states[0] = -94.906835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2087169087, states[0] = -94.599378, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.835106
 - CaMKt in component CaMK (millimolar): 0.006647
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.638182
 - nass in component intracellular_ions (millimolar): 6.638241
 - ki in component intracellular_ions (millimolar): 145.343255
 - kss in component intracellular_ions (millimolar): 145.343236
 - cansr in component intracellular_ions (millimolar): 1.297565
 - cajsr in component intracellular_ions (millimolar): 1.260595
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003643
 - hf in component INa (dimensionless): 0.878838
 - hs in component INa (dimensionless): 0.878833
 - j in component INa (dimensionless): 0.878804
 - hsp in component INa (dimensionless): 0.723643
 - jp in component INa (dimensionless): 0.878785
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709602
 - hLp in component INaL (dimensionless): 0.454383
 - a in component Ito (dimensionless): 0.000626
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.627356
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.703054
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937842
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999897
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001552
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330989
 - xs1 in component IKs (dimensionless): 0.232444
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997355
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:05:12 (47994): called boinc_finish(0)

</stderr_txt>
]]>


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