𝕏

Task 55441626

Name HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_917_0
Workunit 26327033
Created 30 Jun 2024, 12:11:07 UTC
Sent 30 Jun 2024, 13:49:05 UTC
Report deadline 3 Jul 2024, 23:25:05 UTC
Received 30 Jun 2024, 21:26:21 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 2 hours 8 min 14 sec
CPU time 2 hours 1 min 56 sec
Validate state Valid
Credit 60.95
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.05 MB
Peak swap size 4.13 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_917.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_917_0_r272938570_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_917_0_r272938570_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.005173
     * GNaL_b in INaL: 0.004816
     * Gto_b in Ito: 0.072116
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033165
     * GKs_b in IKs: 0.002044
     * GK1_b in IK1: 0.154981
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 72.724392
     * GKb_b in IKb: 0.003829
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.027980
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12370169, states[0] = -94.981126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25381581, states[0] = -94.944148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38119107, states[0] = -49.294937, states[40]= 0.000028
Saving checkpoint... 
Iteration: 51526888, states[0] = 18.878361, states[40]= 0.007241
Saving checkpoint... 
Iteration: 64046163, states[0] = 11.314669, states[40]= 0.005313
Saving checkpoint... 
Iteration: 76771772, states[0] = -94.821360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88995295, states[0] = -94.909521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102493138, states[0] = -94.906117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115617517, states[0] = -45.098539, states[40]= 0.000054
Saving checkpoint... 
Iteration: 128460975, states[0] = -94.898127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141218656, states[0] = -94.737825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153888553, states[0] = -94.879400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166753580, states[0] = -94.788066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179973141, states[0] = -94.897724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192123162, states[0] = -50.985025, states[40]= 0.000021
Saving checkpoint... 
Iteration: 205219116, states[0] = -94.736852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217697589, states[0] = -94.695978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230776676, states[0] = -94.812484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243528106, states[0] = 18.755707, states[40]= 0.006990
Saving checkpoint... 
Iteration: 256425755, states[0] = -94.888305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269897082, states[0] = -94.880694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282215979, states[0] = -94.731043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295505359, states[0] = 29.364403, states[40]= 0.128851
Saving checkpoint... 
Iteration: 308822023, states[0] = -94.847651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321894460, states[0] = -94.879831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334281643, states[0] = -94.816992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347839360, states[0] = -94.857466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360647848, states[0] = -82.889917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373961167, states[0] = -94.895124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387042884, states[0] = 13.004265, states[40]= 0.005446
Saving checkpoint... 
Iteration: 399868753, states[0] = -94.870792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413167513, states[0] = -94.553407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425774145, states[0] = -94.809751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438863996, states[0] = -94.868855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451266847, states[0] = -94.802197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464273282, states[0] = -94.808867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476517107, states[0] = 22.084273, states[40]= 0.014480
Saving checkpoint... 
Iteration: 489391744, states[0] = -94.878882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502289207, states[0] = -94.823613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513521193, states[0] = 20.956288, states[40]= 0.009695
Saving checkpoint... 
Iteration: 526689931, states[0] = -94.679478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538885027, states[0] = -94.876657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551836353, states[0] = -94.855761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565099232, states[0] = -25.993985, states[40]= 0.000613
Saving checkpoint... 
Iteration: 577195832, states[0] = -94.691946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589443938, states[0] = -94.891915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602555184, states[0] = 7.602187, states[40]= 0.005052
Saving checkpoint... 
Iteration: 616144255, states[0] = -77.051718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629385714, states[0] = -94.876839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641621778, states[0] = -49.443095, states[40]= 0.000027
Saving checkpoint... 
Iteration: 653819774, states[0] = -94.846048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665515321, states[0] = 22.557020, states[40]= 0.018674
Saving checkpoint... 
Iteration: 676797682, states[0] = -94.830463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687374760, states[0] = -94.872937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699427928, states[0] = -94.888498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710832136, states[0] = -94.853365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722124912, states[0] = -52.879166, states[40]= 0.000015
Saving checkpoint... 
Iteration: 733928161, states[0] = -94.888532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745640319, states[0] = -71.215143, states[40]= 0.000001
Saving checkpoint... 
Iteration: 756657553, states[0] = -93.208805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768050453, states[0] = 9.738587, states[40]= 0.005178
Saving checkpoint... 
Iteration: 778144505, states[0] = -77.446809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789145348, states[0] = -78.797935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800706370, states[0] = -94.712935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811995054, states[0] = -94.899667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822930076, states[0] = -94.888912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833490824, states[0] = -94.899141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842833378, states[0] = -94.853984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853542046, states[0] = 13.355895, states[40]= 0.005487
Saving checkpoint... 
Iteration: 863230161, states[0] = -94.754299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873946211, states[0] = -94.892200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884574791, states[0] = -3.157501, states[40]= 0.003862
Saving checkpoint... 
Iteration: 895527408, states[0] = 18.996234, states[40]= 0.007145
Saving checkpoint... 
Iteration: 906730431, states[0] = -94.754694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917415868, states[0] = -94.885497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929048867, states[0] = 10.436927, states[40]= 0.005223
Saving checkpoint... 
Iteration: 940788935, states[0] = -94.823144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953175999, states[0] = -94.642888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964719092, states[0] = -94.736095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977653306, states[0] = -90.402973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988369649, states[0] = -94.870827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000309127, states[0] = -94.838781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012975335, states[0] = -94.896969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024806900, states[0] = -94.837190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036442928, states[0] = -94.891478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048887861, states[0] = -94.877327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060888757, states[0] = -94.877614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073229693, states[0] = -94.753457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085793360, states[0] = -94.826775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097898551, states[0] = -94.880646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110142552, states[0] = -74.433706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122757250, states[0] = -94.791025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135605775, states[0] = -32.647390, states[40]= 0.000316
Saving checkpoint... 
Iteration: 1148368547, states[0] = -94.870308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159754674, states[0] = -94.787918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171408074, states[0] = -94.883316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185709157, states[0] = -94.718037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199492215, states[0] = -94.899116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213139089, states[0] = -69.538792, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1227515244, states[0] = 22.577607, states[40]= 0.018902
Saving checkpoint... 
Iteration: 1240183743, states[0] = -94.665235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253690377, states[0] = -94.680047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268136890, states[0] = -66.688821, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1282259526, states[0] = -94.793599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295365349, states[0] = -94.868948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309340067, states[0] = -94.857312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322280090, states[0] = -94.815010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336113430, states[0] = -40.517381, states[40]= 0.000108
Saving checkpoint... 
Iteration: 1348557447, states[0] = 6.545762, states[40]= 0.004990
Saving checkpoint... 
Iteration: 1362810348, states[0] = -94.839436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375063080, states[0] = 3.777048, states[40]= 0.004794
Saving checkpoint... 
Iteration: 1388315323, states[0] = -94.842783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401134448, states[0] = -63.696737, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1414773423, states[0] = -94.808497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431917620, states[0] = -94.885660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448102743, states[0] = -29.562293, states[40]= 0.000445
Saving checkpoint... 
Iteration: 1464443458, states[0] = -94.891352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480716164, states[0] = -94.730692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498501387, states[0] = 48.870829, states[40]= 0.048221
Saving checkpoint... 
Iteration: 1514762470, states[0] = -1.688474, states[40]= 0.004536
Saving checkpoint... 
Iteration: 1531916074, states[0] = -63.514689, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1548417023, states[0] = -65.553648, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1565861080, states[0] = -94.987764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581864283, states[0] = -95.166175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1598202040, states[0] = -47.438931, states[40]= 0.000039
Saving checkpoint... 
Iteration: 1614944510, states[0] = 8.972427, states[40]= 0.005977
Saving checkpoint... 
Iteration: 1630344690, states[0] = -94.829019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1646681229, states[0] = -95.185255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1662822143, states[0] = -95.122043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1679860601, states[0] = -94.995528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1695961463, states[0] = -2.181067, states[40]= 0.004491
Saving checkpoint... 
Iteration: 1712299866, states[0] = -95.085576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1728615099, states[0] = 22.703285, states[40]= 0.020998
Saving checkpoint... 
Iteration: 1745502808, states[0] = -48.554919, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1762902908, states[0] = -48.677952, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1779493699, states[0] = -95.073767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1796131937, states[0] = 15.585318, states[40]= 0.007248
Saving checkpoint... 
Iteration: 1812872034, states[0] = -94.919375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1830211835, states[0] = -94.752833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846173221, states[0] = -94.651067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1862589678, states[0] = -16.864311, states[40]= 0.001264
Saving checkpoint... 
Iteration: 1879280640, states[0] = -94.822174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1896065700, states[0] = 2.301013, states[40]= 0.004660
Saving checkpoint... 
Iteration: 1913578466, states[0] = -5.999851, states[40]= 0.003282
Saving checkpoint... 
Iteration: 1929961460, states[0] = -94.895824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1946788726, states[0] = -94.823319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963861178, states[0] = -94.867378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1980964678, states[0] = -94.895126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1997021622, states[0] = 20.829525, states[40]= 0.009406
Saving checkpoint... 
Iteration: 2015943631, states[0] = -94.891169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2037419465, states[0] = -94.885813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2058197997, states[0] = -94.695602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2075871210, states[0] = -94.870828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2093006252, states[0] = 27.636612, states[40]= 0.113472
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.775398
 - CaMKt in component CaMK (millimolar): 0.006472
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.530084
 - nass in component intracellular_ions (millimolar): 6.530143
 - ki in component intracellular_ions (millimolar): 145.453185
 - kss in component intracellular_ions (millimolar): 145.453166
 - cansr in component intracellular_ions (millimolar): 1.290354
 - cajsr in component intracellular_ions (millimolar): 1.253802
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003665
 - hf in component INa (dimensionless): 0.877789
 - hs in component INa (dimensionless): 0.877785
 - j in component INa (dimensionless): 0.877756
 - hsp in component INa (dimensionless): 0.721677
 - jp in component INa (dimensionless): 0.877736
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.708481
 - hLp in component INaL (dimensionless): 0.454043
 - a in component Ito (dimensionless): 0.000629
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.629509
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.705785
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.940456
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999904
 - jca in component ICaL (dimensionless): 0.999982
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001534
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.328505
 - xs1 in component IKs (dimensionless): 0.226589
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997370
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:26:07 (99122): called boinc_finish(0)

</stderr_txt>
]]>


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