𝕏

Task 55441625

Name HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_817_1
Workunit 26327032
Created 30 Jun 2024, 12:11:07 UTC
Sent 30 Jun 2024, 13:49:05 UTC
Report deadline 3 Jul 2024, 23:25:05 UTC
Received 30 Jun 2024, 21:20:47 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 2 hours 13 min 5 sec
CPU time 2 hours 3 min 57 sec
Validate state Valid
Credit 57.55
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.06 MB
Peak swap size 4.13 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_817.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_817_1_r233357371_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_817_1_r233357371_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.309406
     * GNaL_b in INaL: 0.006352
     * Gto_b in Ito: 0.080699
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033560
     * GKs_b in IKs: 0.001823
     * GK1_b in IK1: 0.175809
     * Gncx_b in INaCa_i: 0.000959
     * Pnak_b in INaK: 73.304965
     * GKb_b in IKb: 0.003797
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.042617
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11843034, states[0] = -95.166536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24939389, states[0] = -95.157478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36816908, states[0] = -95.097246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49409758, states[0] = -95.119801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62686193, states[0] = -94.919929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75717073, states[0] = -94.970099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88809335, states[0] = -95.061843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101153783, states[0] = -85.851018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114595628, states[0] = -16.076548, states[40]= 0.001324
Saving checkpoint... 
Iteration: 127041296, states[0] = 15.063958, states[40]= 0.005193
Saving checkpoint... 
Iteration: 140376785, states[0] = -95.086673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152835893, states[0] = -95.069895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165858771, states[0] = -95.079409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178891817, states[0] = -95.090108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191607657, states[0] = -27.534435, states[40]= 0.000570
Saving checkpoint... 
Iteration: 204022118, states[0] = 21.115524, states[40]= 0.008231
Saving checkpoint... 
Iteration: 216332920, states[0] = -95.067460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229953400, states[0] = -95.102900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242954192, states[0] = -95.102982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255739206, states[0] = -94.990166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269173847, states[0] = -94.859677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282037687, states[0] = 16.416645, states[40]= 0.005367
Saving checkpoint... 
Iteration: 295314842, states[0] = -95.057456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309193968, states[0] = -94.917956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322709815, states[0] = -94.946484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335684278, states[0] = -94.898660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348581299, states[0] = -3.679685, states[40]= 0.003650
Saving checkpoint... 
Iteration: 361134528, states[0] = -55.946246, states[40]= 0.000010
Saving checkpoint... 
Iteration: 374157772, states[0] = -91.021077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387484268, states[0] = -95.106950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400733745, states[0] = -94.982838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413389742, states[0] = -95.088865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425803214, states[0] = -95.050059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439162442, states[0] = -93.947776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452133791, states[0] = -55.073855, states[40]= 0.000012
Saving checkpoint... 
Iteration: 465628093, states[0] = -48.513619, states[40]= 0.000035
Saving checkpoint... 
Iteration: 478809954, states[0] = -95.054360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491478063, states[0] = -95.106126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504918681, states[0] = -95.096105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517479650, states[0] = -95.106308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530290630, states[0] = -95.041072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543225883, states[0] = -94.971689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556151118, states[0] = -80.082739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569476002, states[0] = -95.105815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581630662, states[0] = -51.433375, states[40]= 0.000022
Saving checkpoint... 
Iteration: 595002551, states[0] = 39.634497, states[40]= 0.120226
Saving checkpoint... 
Iteration: 608153730, states[0] = -85.004030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620476729, states[0] = -95.105877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632710970, states[0] = -94.948229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643800855, states[0] = -95.048336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656451167, states[0] = -95.102167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669448276, states[0] = -95.101684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682127028, states[0] = -47.322125, states[40]= 0.000042
Saving checkpoint... 
Iteration: 695394519, states[0] = -95.090034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707384621, states[0] = -95.087171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719499983, states[0] = -95.108476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731535458, states[0] = 17.197822, states[40]= 0.005514
Saving checkpoint... 
Iteration: 744050513, states[0] = 11.555374, states[40]= 0.004970
Saving checkpoint... 
Iteration: 755478545, states[0] = -95.106022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767203992, states[0] = -94.936098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779170773, states[0] = -94.817866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789682157, states[0] = -94.893620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801589189, states[0] = -9.893758, states[40]= 0.002354
Saving checkpoint... 
Iteration: 813825316, states[0] = -95.063010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826030394, states[0] = 18.859988, states[40]= 0.006022
Saving checkpoint... 
Iteration: 837362215, states[0] = -95.079550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848846419, states[0] = -95.073171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860456595, states[0] = -95.102899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872008784, states[0] = 24.006155, states[40]= 0.068068
Saving checkpoint... 
Iteration: 882301093, states[0] = -95.048349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893564595, states[0] = 5.576461, states[40]= 0.004746
Saving checkpoint... 
Iteration: 904699824, states[0] = -94.928499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916313394, states[0] = -95.056190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926203481, states[0] = -94.935089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936648784, states[0] = -75.801285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945923037, states[0] = -95.096769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955475069, states[0] = -95.105455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964613562, states[0] = -33.296698, states[40]= 0.000314
Saving checkpoint... 
Iteration: 975361747, states[0] = -95.079289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985793665, states[0] = -95.043045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997853068, states[0] = -95.075878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009294985, states[0] = -95.043990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019827467, states[0] = -95.064018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031576959, states[0] = -0.873819, states[40]= 0.004123
Saving checkpoint... 
Iteration: 1044117550, states[0] = -37.279370, states[40]= 0.000186
Saving checkpoint... 
Iteration: 1056231157, states[0] = -94.978882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067650449, states[0] = -78.824998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079269686, states[0] = -95.023100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091615640, states[0] = -35.360512, states[40]= 0.000241
Saving checkpoint... 
Iteration: 1104391487, states[0] = -95.088933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114978418, states[0] = -95.105783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127436599, states[0] = -95.099343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139437077, states[0] = -95.099424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151364215, states[0] = -95.080095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163721934, states[0] = -94.965417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176233301, states[0] = -94.981751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188035810, states[0] = 17.076367, states[40]= 0.005488
Saving checkpoint... 
Iteration: 1200752290, states[0] = -95.005200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213115495, states[0] = -35.215717, states[40]= 0.000246
Saving checkpoint... 
Iteration: 1225261147, states[0] = -95.014659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237088846, states[0] = -9.593418, states[40]= 0.002416
Saving checkpoint... 
Iteration: 1249865495, states[0] = -95.080500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261163383, states[0] = -94.191475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272451610, states[0] = -95.101856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286087407, states[0] = -8.361327, states[40]= 0.002676
Saving checkpoint... 
Iteration: 1299683103, states[0] = -94.895472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314048646, states[0] = 12.292603, states[40]= 0.004999
Saving checkpoint... 
Iteration: 1327271866, states[0] = -95.024961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341268820, states[0] = -95.022122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354889718, states[0] = -95.088272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367069208, states[0] = 3.364315, states[40]= 0.004598
Saving checkpoint... 
Iteration: 1380849715, states[0] = -95.074251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394812502, states[0] = -95.055354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407813205, states[0] = -95.055771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421889451, states[0] = -95.088154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435829021, states[0] = -95.064566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449998693, states[0] = -95.107890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462775717, states[0] = -95.028331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476566621, states[0] = 4.626632, states[40]= 0.004689
Saving checkpoint... 
Iteration: 1489927212, states[0] = -95.097295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1503213539, states[0] = -95.235871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1517069539, states[0] = -95.309103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1533233454, states[0] = -95.288480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1548532013, states[0] = -95.295538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564211345, states[0] = 23.680036, states[40]= 0.038818
Saving checkpoint... 
Iteration: 1580997018, states[0] = -95.359307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1596851549, states[0] = -95.327235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1613156183, states[0] = 3.956091, states[40]= 0.005262
Saving checkpoint... 
Iteration: 1629169687, states[0] = -95.202886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1644701333, states[0] = -40.518719, states[40]= 0.000120
Saving checkpoint... 
Iteration: 1661599094, states[0] = -95.262175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1678089187, states[0] = -95.244516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1693656820, states[0] = -95.170055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1709673013, states[0] = -95.347999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1725554935, states[0] = -95.333048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1741773798, states[0] = -95.348602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1757393332, states[0] = -95.361696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1773845660, states[0] = -95.324133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1790150843, states[0] = 7.014225, states[40]= 0.005526
Saving checkpoint... 
Iteration: 1806643667, states[0] = -73.707983, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1822638291, states[0] = -63.607003, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1839047943, states[0] = 12.211918, states[40]= 0.005018
Saving checkpoint... 
Iteration: 1855698396, states[0] = -94.937116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1871722290, states[0] = -94.972826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1888025141, states[0] = 20.318604, states[40]= 0.007044
Saving checkpoint... 
Iteration: 1904248128, states[0] = -95.002699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1920826919, states[0] = -95.064768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1937776936, states[0] = -95.030046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1954888890, states[0] = -95.088198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1972299490, states[0] = -95.046872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1989013095, states[0] = 22.819821, states[40]= 0.025972
Saving checkpoint... 
Iteration: 2006089825, states[0] = -10.462937, states[40]= 0.002239
Saving checkpoint... 
Iteration: 2022806053, states[0] = -95.050949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2039525184, states[0] = 20.359408, states[40]= 0.007041
Saving checkpoint... 
Iteration: 2056575816, states[0] = -0.195440, states[40]= 0.004218
Saving checkpoint... 
Iteration: 2073214756, states[0] = -94.953537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2091296064, states[0] = -95.044047, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.983449
 - CaMKt in component CaMK (millimolar): 0.006857
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.506273
 - nass in component intracellular_ions (millimolar): 6.506333
 - ki in component intracellular_ions (millimolar): 145.473036
 - kss in component intracellular_ions (millimolar): 145.473017
 - cansr in component intracellular_ions (millimolar): 1.304366
 - cajsr in component intracellular_ions (millimolar): 1.266578
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003589
 - hf in component INa (dimensionless): 0.881409
 - hs in component INa (dimensionless): 0.881405
 - j in component INa (dimensionless): 0.881380
 - hsp in component INa (dimensionless): 0.728493
 - jp in component INa (dimensionless): 0.881363
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.712887
 - hLp in component INaL (dimensionless): 0.456946
 - a in component Ito (dimensionless): 0.000620
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.624049
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.699457
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935066
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999887
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001576
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.324597
 - xs1 in component IKs (dimensionless): 0.240830
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997316
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:20:19 (99035): called boinc_finish(0)

</stderr_txt>
]]>


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