𝕏

Task 55441624

Name HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_817_0
Workunit 26327032
Created 30 Jun 2024, 12:11:07 UTC
Sent 30 Jun 2024, 13:51:17 UTC
Report deadline 3 Jul 2024, 23:27:17 UTC
Received 1 Jul 2024, 17:10:49 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238614
Run time 2 hours 34 min 43 sec
CPU time 2 hours 34 min 24 sec
Validate state Valid
Credit 57.55
Device peak FLOPS 3.71 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.93 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.14.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_817.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_817_0_r807663990_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141057895232_ORdGradInc_k_25-Pueyo_APDR-conf_817_0_r807663990_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.309406
     * GNaL_b in INaL: 0.006352
     * Gto_b in Ito: 0.080699
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033560
     * GKs_b in IKs: 0.001823
     * GK1_b in IK1: 0.175809
     * Gncx_b in INaCa_i: 0.000959
     * Pnak_b in INaK: 73.304965
     * GKb_b in IKb: 0.003797
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.042617
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13971175, states[0] = -95.190750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27877130, states[0] = -95.136837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40778247, states[0] = -95.065418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55779283, states[0] = -95.053377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66947911, states[0] = -95.116751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82030726, states[0] = 18.630513, states[40]= 0.005970
Saving checkpoint... 
Iteration: 97948048, states[0] = -95.107749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110928528, states[0] = -95.102304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121944545, states[0] = -95.104182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132922283, states[0] = -95.099122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144931879, states[0] = -95.100457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155837060, states[0] = -95.070356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168065717, states[0] = 5.036043, states[40]= 0.004716
Saving checkpoint... 
Iteration: 180775428, states[0] = -95.029359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192871774, states[0] = -95.083698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205746801, states[0] = -94.999731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220959337, states[0] = -95.103857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232818458, states[0] = -95.059684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244876167, states[0] = -95.084870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256979600, states[0] = -95.106513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268227466, states[0] = -94.974193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279336405, states[0] = -95.068978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290375662, states[0] = -95.084624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305135722, states[0] = -57.374360, states[40]= 0.000008
Saving checkpoint... 
Iteration: 316526000, states[0] = 20.141255, states[40]= 0.006823
Saving checkpoint... 
Iteration: 327867686, states[0] = -95.081864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338784140, states[0] = -95.036130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349994733, states[0] = -95.108158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360843335, states[0] = -95.072116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373719117, states[0] = -94.961577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384672380, states[0] = -94.844276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395460494, states[0] = -95.103779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407599269, states[0] = -19.375539, states[40]= 0.001002
Saving checkpoint... 
Iteration: 421787061, states[0] = -95.038396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433561621, states[0] = 6.919538, states[40]= 0.004811
Saving checkpoint... 
Iteration: 444918858, states[0] = -95.096182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455722375, states[0] = -94.966527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469509062, states[0] = 23.877813, states[40]= 0.063790
Saving checkpoint... 
Iteration: 481041203, states[0] = 15.138247, states[40]= 0.005196
Saving checkpoint... 
Iteration: 492684731, states[0] = -94.899524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504426623, states[0] = -95.097787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516891752, states[0] = -95.089373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527908592, states[0] = -95.093768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538798569, states[0] = -95.046827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550592858, states[0] = -13.232367, states[40]= 0.001730
Saving checkpoint... 
Iteration: 562864612, states[0] = -95.080606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573884079, states[0] = -95.087090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585048257, states[0] = 12.444857, states[40]= 0.005006
Saving checkpoint... 
Iteration: 596303164, states[0] = -95.049920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609676076, states[0] = -94.873953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621629102, states[0] = -49.652787, states[40]= 0.000029
Saving checkpoint... 
Iteration: 633941688, states[0] = -95.100573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646555496, states[0] = 9.536118, states[40]= 0.004904
Saving checkpoint... 
Iteration: 657793892, states[0] = -95.043415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668492520, states[0] = -95.107717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681145598, states[0] = -70.541447, states[40]= 0.000001
Saving checkpoint... 
Iteration: 692382791, states[0] = -95.086623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704772070, states[0] = -95.025536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715769062, states[0] = -95.022741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726384748, states[0] = -95.087197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740250568, states[0] = -95.003542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754977870, states[0] = -95.105938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770422633, states[0] = -95.096793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782148759, states[0] = -75.757526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796241507, states[0] = -94.992688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811456114, states[0] = -95.102855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828679589, states[0] = -94.886963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840489465, states[0] = -95.107270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852188978, states[0] = -94.907944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863880195, states[0] = -95.085708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878670816, states[0] = -94.818678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892091504, states[0] = -11.976080, states[40]= 0.001949
Saving checkpoint... 
Iteration: 903831791, states[0] = -95.066304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919772006, states[0] = -95.025343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931958789, states[0] = -95.103190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942914228, states[0] = -95.094835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954944388, states[0] = -95.100847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967313692, states[0] = -95.056337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978773753, states[0] = -95.026888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990290441, states[0] = -95.040643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005078653, states[0] = -1.923366, states[40]= 0.003960
Saving checkpoint... 
Iteration: 1017351224, states[0] = -95.075108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028392059, states[0] = -95.089142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039745322, states[0] = -94.997214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055180768, states[0] = -94.890037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066886582, states[0] = -95.087535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078889008, states[0] = -95.088239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089636928, states[0] = -58.835095, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1101055462, states[0] = 9.550277, states[40]= 0.004905
Saving checkpoint... 
Iteration: 1112476923, states[0] = -95.105596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124965693, states[0] = -95.104079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136908084, states[0] = -95.093266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148652577, states[0] = -82.853335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161728281, states[0] = -94.974767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175877335, states[0] = -95.084601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188358576, states[0] = -95.077948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200426393, states[0] = -95.097308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211752553, states[0] = -95.005487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222889094, states[0] = -95.088174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234048847, states[0] = 12.213686, states[40]= 0.004996
Saving checkpoint... 
Iteration: 1248909715, states[0] = -95.093589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260293253, states[0] = -95.042572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271518205, states[0] = 21.937528, states[40]= 0.011552
Saving checkpoint... 
Iteration: 1285209340, states[0] = -94.945068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296826418, states[0] = -95.063295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308703727, states[0] = -94.935288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319674069, states[0] = -94.860785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334103229, states[0] = -23.212310, states[40]= 0.000773
Saving checkpoint... 
Iteration: 1345889530, states[0] = -95.088224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357665089, states[0] = -94.484537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369004239, states[0] = 30.798663, states[40]= 0.152242
Saving checkpoint... 
Iteration: 1381167185, states[0] = -94.679845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392484702, states[0] = -95.106377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405202656, states[0] = -94.933315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416248672, states[0] = -95.000939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431077764, states[0] = -1.365705, states[40]= 0.004049
Saving checkpoint... 
Iteration: 1442350754, states[0] = -95.074648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454643944, states[0] = -68.067310, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1467732531, states[0] = -94.980519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479132492, states[0] = -53.550165, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1490998054, states[0] = -95.107798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1504008787, states[0] = -45.519287, states[40]= 0.000053
Saving checkpoint... 
Iteration: 1516555455, states[0] = 5.249703, states[40]= 0.005320
Saving checkpoint... 
Iteration: 1528181822, states[0] = -95.328175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1539949985, states[0] = 7.857915, states[40]= 0.005568
Saving checkpoint... 
Iteration: 1551844780, states[0] = -95.310985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1563240051, states[0] = -95.309892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1574741308, states[0] = 12.133937, states[40]= 0.005978
Saving checkpoint... 
Iteration: 1587265922, states[0] = -95.338788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1599700390, states[0] = -39.293626, states[40]= 0.000143
Saving checkpoint... 
Iteration: 1610536670, states[0] = -92.475964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1621618540, states[0] = -62.515344, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1632683523, states[0] = -20.458305, states[40]= 0.001001
Saving checkpoint... 
Iteration: 1643841955, states[0] = -94.690141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1655231033, states[0] = -84.405557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1666373016, states[0] = -95.211106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1679049410, states[0] = -95.327747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1690138699, states[0] = -95.316769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1701204603, states[0] = -95.271469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1712234228, states[0] = -89.927778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1725556675, states[0] = -95.334621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1738500085, states[0] = -84.910590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1750238238, states[0] = 13.545006, states[40]= 0.006177
Saving checkpoint... 
Iteration: 1761736196, states[0] = -92.166885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1772768463, states[0] = -4.849673, states[40]= 0.003854
Saving checkpoint... 
Iteration: 1783653412, states[0] = -95.155839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1797432314, states[0] = -86.871251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1809176088, states[0] = -94.915954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1819893645, states[0] = -95.122781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1830423495, states[0] = -95.121252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1840172626, states[0] = -94.876016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1849888760, states[0] = -95.101586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1860021610, states[0] = 21.123063, states[40]= 0.008475
Saving checkpoint... 
Iteration: 1870270758, states[0] = -95.031169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880748949, states[0] = -95.006498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1890965933, states[0] = -95.107618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1900995050, states[0] = -95.110157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1911815444, states[0] = -95.058903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1922683272, states[0] = -94.896992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932614278, states[0] = -34.084645, states[40]= 0.000284
Saving checkpoint... 
Iteration: 1942867219, states[0] = -95.081485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1952665197, states[0] = -94.504524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1964030095, states[0] = 18.946586, states[40]= 0.006062
Saving checkpoint... 
Iteration: 1979080938, states[0] = -3.442091, states[40]= 0.003694
Saving checkpoint... 
Iteration: 1988792338, states[0] = -95.041604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2002976669, states[0] = -95.105096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2013096902, states[0] = -17.092200, states[40]= 0.001207
Saving checkpoint... 
Iteration: 2023944532, states[0] = -95.100227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2034199097, states[0] = -94.926459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2044452604, states[0] = -95.101522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2054866785, states[0] = -95.080438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2064621995, states[0] = -41.865890, states[40]= 0.000096
Saving checkpoint... 
Iteration: 2074530390, states[0] = 18.861250, states[40]= 0.006023
Saving checkpoint... 
Iteration: 2084558982, states[0] = 8.068669, states[40]= 0.004856
Saving checkpoint... 
Iteration: 2094426930, states[0] = -95.096816, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.983449
 - CaMKt in component CaMK (millimolar): 0.006857
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.506273
 - nass in component intracellular_ions (millimolar): 6.506333
 - ki in component intracellular_ions (millimolar): 145.473036
 - kss in component intracellular_ions (millimolar): 145.473017
 - cansr in component intracellular_ions (millimolar): 1.304366
 - cajsr in component intracellular_ions (millimolar): 1.266578
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003589
 - hf in component INa (dimensionless): 0.881409
 - hs in component INa (dimensionless): 0.881405
 - j in component INa (dimensionless): 0.881380
 - hsp in component INa (dimensionless): 0.728493
 - jp in component INa (dimensionless): 0.881363
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.712887
 - hLp in component INaL (dimensionless): 0.456946
 - a in component Ito (dimensionless): 0.000620
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.624049
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.699457
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935066
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999887
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001576
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.324597
 - xs1 in component IKs (dimensionless): 0.240830
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997316
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:01:03 (94494): called boinc_finish(0)

</stderr_txt>
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