𝕏

Task 55441314

Name HuVeMOp_20240630141042538093_ORdGradInc_k_25-Pueyo_APDR-conf_241_0
Workunit 26326877
Created 30 Jun 2024, 12:10:57 UTC
Sent 30 Jun 2024, 13:47:36 UTC
Report deadline 3 Jul 2024, 23:23:36 UTC
Received 3 Jul 2024, 9:36:03 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232269
Run time 2 hours 39 min 12 sec
CPU time 2 hours 28 min 51 sec
Validate state Valid
Credit 55.89
Device peak FLOPS 3.96 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.88 MB
Peak swap size 3.95 MB
Peak disk usage 0.49 MB

Stderr output

<core_client_version>7.16.6</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141042538093_ORdGradInc_k_25-Pueyo_APDR-conf_241.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141042538093_ORdGradInc_k_25-Pueyo_APDR-conf_241_0_r749521355_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141042538093_ORdGradInc_k_25-Pueyo_APDR-conf_241_0_r749521355_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 107.303843
     * GNaL_b in INaL: 0.005225
     * Gto_b in Ito: 0.076554
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033382
     * GKs_b in IKs: 0.001779
     * GK1_b in IK1: 0.165021
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 65.952836
     * GKb_b in IKb: 0.003862
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8042147, states[0] = 12.577433, states[40]= 0.005376
Saving checkpoint... 
Iteration: 16079585, states[0] = -7.820425, states[40]= 0.002878
Saving checkpoint... 
Iteration: 23748317, states[0] = -94.807746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31703770, states[0] = -94.731753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39799595, states[0] = -94.843194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47708682, states[0] = -94.731009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55778752, states[0] = -94.819637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63509437, states[0] = 23.991029, states[40]= 0.060305
Saving checkpoint... 
Iteration: 71576142, states[0] = -4.037238, states[40]= 0.003704
Saving checkpoint... 
Iteration: 79799934, states[0] = -94.831405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87939035, states[0] = -94.885604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95885927, states[0] = -94.871615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103983784, states[0] = -94.891057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111990159, states[0] = -94.891301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119957678, states[0] = -94.886422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127730879, states[0] = -94.754789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135750787, states[0] = -94.780975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143679199, states[0] = -94.658116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151331587, states[0] = -94.846601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159407636, states[0] = -94.875089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167024602, states[0] = 19.724852, states[40]= 0.007614
Saving checkpoint... 
Iteration: 174819013, states[0] = -94.839171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182753042, states[0] = -94.782867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190841092, states[0] = -94.850963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198544153, states[0] = 12.515000, states[40]= 0.005316
Saving checkpoint... 
Iteration: 206598506, states[0] = -24.515662, states[40]= 0.000707
Saving checkpoint... 
Iteration: 214504513, states[0] = 31.098195, states[40]= 0.150370
Saving checkpoint... 
Iteration: 222348771, states[0] = -94.854405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230517313, states[0] = 21.706435, states[40]= 0.013515
Saving checkpoint... 
Iteration: 238254472, states[0] = -94.784290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246077031, states[0] = -4.448389, states[40]= 0.003616
Saving checkpoint... 
Iteration: 254012329, states[0] = 22.956402, states[40]= 0.031644
Saving checkpoint... 
Iteration: 262148248, states[0] = -83.332687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270072001, states[0] = -1.017774, states[40]= 0.004236
Saving checkpoint... 
Iteration: 278148799, states[0] = -84.270577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286339175, states[0] = -94.849780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294089603, states[0] = -15.620652, states[40]= 0.001424
Saving checkpoint... 
Iteration: 302180763, states[0] = -94.661031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310413260, states[0] = -94.875910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318577161, states[0] = -4.543642, states[40]= 0.003596
Saving checkpoint... 
Iteration: 326565236, states[0] = 2.860318, states[40]= 0.004708
Saving checkpoint... 
Iteration: 334586250, states[0] = -12.351917, states[40]= 0.001946
Saving checkpoint... 
Iteration: 342485173, states[0] = -94.888585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350699434, states[0] = -94.699791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358727848, states[0] = -94.748852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366673212, states[0] = -94.636757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374704090, states[0] = -94.708642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382717489, states[0] = -94.732368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390402118, states[0] = -94.872995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398528150, states[0] = 18.602541, states[40]= 0.006719
Saving checkpoint... 
Iteration: 406363526, states[0] = -94.860390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414240895, states[0] = -94.767312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422407518, states[0] = -94.874398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430418049, states[0] = -94.876969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438347258, states[0] = -94.853506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446248430, states[0] = -94.776913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454343872, states[0] = -94.851927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461974707, states[0] = -94.887156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470127169, states[0] = -54.349204, states[40]= 0.000013
Saving checkpoint... 
Iteration: 477942878, states[0] = -94.882091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485958541, states[0] = -94.884765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493855880, states[0] = -94.857242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502105416, states[0] = -31.412202, states[40]= 0.000384
Saving checkpoint... 
Iteration: 510087278, states[0] = -13.340902, states[40]= 0.001771
Saving checkpoint... 
Iteration: 518218982, states[0] = -94.734757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526273809, states[0] = -94.804303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534391999, states[0] = -94.870034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542373589, states[0] = -94.864046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550164818, states[0] = -94.497284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558206488, states[0] = -94.712971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566196350, states[0] = -94.693618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573974523, states[0] = -94.887061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582061267, states[0] = 4.879690, states[40]= 0.004868
Saving checkpoint... 
Iteration: 590051119, states[0] = 9.555390, states[40]= 0.005122
Saving checkpoint... 
Iteration: 598006960, states[0] = 26.012259, states[40]= 0.104879
Saving checkpoint... 
Iteration: 605961855, states[0] = -94.885208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614043196, states[0] = 12.912751, states[40]= 0.005352
Saving checkpoint... 
Iteration: 622075862, states[0] = -3.596977, states[40]= 0.003786
Saving checkpoint... 
Iteration: 629591930, states[0] = -17.934817, states[40]= 0.001154
Saving checkpoint... 
Iteration: 637530972, states[0] = 17.635668, states[40]= 0.006270
Saving checkpoint... 
Iteration: 645587830, states[0] = -13.877340, states[40]= 0.001683
Saving checkpoint... 
Iteration: 653744424, states[0] = -94.771760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661829415, states[0] = -94.844486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669831551, states[0] = -94.845627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677861377, states[0] = -94.859374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686060223, states[0] = 5.388650, states[40]= 0.004902
Saving checkpoint... 
Iteration: 694205814, states[0] = -94.711645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702087015, states[0] = -13.086399, states[40]= 0.001815
Saving checkpoint... 
Iteration: 709859397, states[0] = -94.858559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717993463, states[0] = -94.889326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726030201, states[0] = 17.905631, states[40]= 0.006378
Saving checkpoint... 
Iteration: 734162268, states[0] = -94.331397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742193296, states[0] = -94.687411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750171856, states[0] = -94.628718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758165878, states[0] = -94.536544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765884415, states[0] = -94.867551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774030239, states[0] = 17.892434, states[40]= 0.006372
Saving checkpoint... 
Iteration: 782077515, states[0] = -4.808607, states[40]= 0.003542
Saving checkpoint... 
Iteration: 790020659, states[0] = 20.853492, states[40]= 0.009616
Saving checkpoint... 
Iteration: 797990719, states[0] = -94.888961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805950382, states[0] = -94.883220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814142686, states[0] = -73.977782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821995544, states[0] = -94.889494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829870486, states[0] = -94.862751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837862085, states[0] = -94.859555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845976344, states[0] = -94.887137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854112472, states[0] = -38.537651, states[40]= 0.000153
Saving checkpoint... 
Iteration: 861873612, states[0] = -94.863855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869790929, states[0] = -94.818956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877933999, states[0] = -94.880136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885790748, states[0] = -94.818802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893764118, states[0] = -94.794429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901742057, states[0] = -94.768538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909834617, states[0] = -94.847081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918010285, states[0] = 23.652353, states[40]= 0.049629
Saving checkpoint... 
Iteration: 925697071, states[0] = -94.694814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933730002, states[0] = -94.751712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941711312, states[0] = -94.721415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949719525, states[0] = -94.735377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957229356, states[0] = -94.750738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965008368, states[0] = 24.696047, states[40]= 0.077078
Saving checkpoint... 
Iteration: 972754666, states[0] = -94.784002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980704021, states[0] = -94.708131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988543448, states[0] = 12.809053, states[40]= 0.005342
Saving checkpoint... 
Iteration: 996707889, states[0] = -94.715254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004852483, states[0] = -94.855475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012312574, states[0] = -94.834335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020374283, states[0] = -94.863993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028481717, states[0] = -94.887724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036466113, states[0] = -94.885581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044543634, states[0] = 12.732344, states[40]= 0.005335
Saving checkpoint... 
Iteration: 1052518327, states[0] = 21.456598, states[40]= 0.011974
Saving checkpoint... 
Iteration: 1060387813, states[0] = -94.868436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068347598, states[0] = -94.853267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076492641, states[0] = -94.889009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084455155, states[0] = -94.883846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092601997, states[0] = -27.993296, states[40]= 0.000540
Saving checkpoint... 
Iteration: 1100654679, states[0] = -91.800378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108150797, states[0] = -87.448249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116025488, states[0] = 19.457853, states[40]= 0.007341
Saving checkpoint... 
Iteration: 1124000638, states[0] = 40.077949, states[40]= 0.003728
Saving checkpoint... 
Iteration: 1131488453, states[0] = -94.888487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139516255, states[0] = 21.963660, states[40]= 0.015625
Saving checkpoint... 
Iteration: 1147601307, states[0] = -27.304158, states[40]= 0.000572
Saving checkpoint... 
Iteration: 1155774714, states[0] = -94.804761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163727061, states[0] = -94.747151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171691575, states[0] = -94.683654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179881258, states[0] = -94.866268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187923707, states[0] = -94.877779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195936600, states[0] = -94.880452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203566383, states[0] = 2.247544, states[40]= 0.004649
Saving checkpoint... 
Iteration: 1211425642, states[0] = -94.878187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219509744, states[0] = 23.892132, states[40]= 0.056182
Saving checkpoint... 
Iteration: 1227823755, states[0] = -94.840976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235975818, states[0] = -94.886824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243910156, states[0] = -94.874555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251955928, states[0] = -94.883868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259784876, states[0] = -94.813749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267652204, states[0] = -89.347697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275739895, states[0] = -94.765438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283405218, states[0] = -94.873264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291438450, states[0] = -94.880751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299400531, states[0] = -94.871995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307547997, states[0] = 10.902487, states[40]= 0.005198
Saving checkpoint... 
Iteration: 1315458084, states[0] = -94.884175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323578123, states[0] = -5.271747, states[40]= 0.003444
Saving checkpoint... 
Iteration: 1331682740, states[0] = -94.664904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339489636, states[0] = -94.888497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347363088, states[0] = -94.859632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355007376, states[0] = 25.550151, states[40]= 0.096076
Saving checkpoint... 
Iteration: 1362973973, states[0] = -94.886494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370851180, states[0] = -94.854678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378689039, states[0] = -94.678317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386438679, states[0] = -94.880736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394599160, states[0] = -25.160446, states[40]= 0.000676
Saving checkpoint... 
Iteration: 1402575834, states[0] = -3.576714, states[40]= 0.003789
Saving checkpoint... 
Iteration: 1410654828, states[0] = -91.911730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418737539, states[0] = -94.762153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426517516, states[0] = 21.657488, states[40]= 0.013173
Saving checkpoint... 
Iteration: 1434605362, states[0] = -31.357536, states[40]= 0.000386
Saving checkpoint... 
Iteration: 1442757946, states[0] = -94.787424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450391398, states[0] = -94.869283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458042617, states[0] = 13.150641, states[40]= 0.005375
Saving checkpoint... 
Iteration: 1465835487, states[0] = -94.847180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473762652, states[0] = -94.792522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481758181, states[0] = -94.787661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489706172, states[0] = -94.711805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497507601, states[0] = 25.328857, states[40]= 0.091498
Saving checkpoint... 
Iteration: 1505547363, states[0] = -94.792772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1513738742, states[0] = -95.074926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1521753877, states[0] = -94.916370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1529512923, states[0] = -58.526729, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1537435005, states[0] = -95.091096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1545506094, states[0] = -95.054759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1552887636, states[0] = -29.249596, states[40]= 0.000480
Saving checkpoint... 
Iteration: 1560830446, states[0] = -95.096706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1568693284, states[0] = -95.156583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1576732335, states[0] = -95.103212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1584570958, states[0] = -95.143627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1592496427, states[0] = -39.873211, states[40]= 0.000130
Saving checkpoint... 
Iteration: 1600408756, states[0] = -95.073113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1608437614, states[0] = -94.036704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1616584067, states[0] = -95.028725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1624685658, states[0] = -95.032431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1632430933, states[0] = -89.156164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1639956312, states[0] = -94.961614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1648017343, states[0] = -66.485835, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1656051843, states[0] = 4.728413, states[40]= 0.005515
Saving checkpoint... 
Iteration: 1664103404, states[0] = 36.968741, states[40]= 0.117390
Saving checkpoint... 
Iteration: 1672050351, states[0] = -94.934502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1679942438, states[0] = -95.121031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1687715364, states[0] = -95.086083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1695645850, states[0] = 8.267891, states[40]= 0.005878
Saving checkpoint... 
Iteration: 1703808376, states[0] = -54.647013, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1711777098, states[0] = -95.153122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1719753843, states[0] = -94.953377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1727777165, states[0] = -17.915521, states[40]= 0.001276
Saving checkpoint... 
Iteration: 1735764971, states[0] = -95.143299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1743791668, states[0] = -95.045682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1751905819, states[0] = -95.071121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1759647066, states[0] = -94.899806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1767723882, states[0] = -76.993124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1775711345, states[0] = 23.812473, states[40]= 0.040229
Saving checkpoint... 
Iteration: 1783557235, states[0] = 1.183871, states[40]= 0.005084
Saving checkpoint... 
Iteration: 1791485302, states[0] = -95.032916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1799468923, states[0] = -8.756360, states[40]= 0.002996
Saving checkpoint... 
Iteration: 1807521834, states[0] = 20.057199, states[40]= 0.008437
Saving checkpoint... 
Iteration: 1815464158, states[0] = -94.925827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1823160731, states[0] = -94.432155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1831134508, states[0] = -65.157782, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1839165455, states[0] = -94.583845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1847369055, states[0] = -94.878292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1855138347, states[0] = -68.998427, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1862983113, states[0] = -94.897913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1870854530, states[0] = -94.864181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1878654708, states[0] = -92.177434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1886604506, states[0] = -30.821301, states[40]= 0.000409
Saving checkpoint... 
Iteration: 1894647901, states[0] = -83.251737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1902655064, states[0] = -92.248091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1910881811, states[0] = -94.868548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919011830, states[0] = 23.090675, states[40]= 0.035174
Saving checkpoint... 
Iteration: 1926939641, states[0] = -94.882160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1934520321, states[0] = 20.931424, states[40]= 0.009877
Saving checkpoint... 
Iteration: 1942508079, states[0] = 24.908466, states[40]= 0.082296
Saving checkpoint... 
Iteration: 1950563563, states[0] = 3.710250, states[40]= 0.004782
Saving checkpoint... 
Iteration: 1958530991, states[0] = 17.621232, states[40]= 0.006267
Saving checkpoint... 
Iteration: 1966377378, states[0] = -94.864941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1973956128, states[0] = -94.883812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1982042008, states[0] = 13.394672, states[40]= 0.005401
Saving checkpoint... 
Iteration: 1990070701, states[0] = -0.224058, states[40]= 0.004353
Saving checkpoint... 
Iteration: 1998012989, states[0] = 22.772293, states[40]= 0.027632
Saving checkpoint... 
Iteration: 2006058906, states[0] = 6.016517, states[40]= 0.004940
Saving checkpoint... 
Iteration: 2013968208, states[0] = -94.885354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2021982275, states[0] = -94.887225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2029791787, states[0] = -94.818940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2037749360, states[0] = -94.777065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2045631675, states[0] = -59.490264, states[40]= 0.000005
Saving checkpoint... 
Iteration: 2052827088, states[0] = -94.842330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2060880286, states[0] = -94.865377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2068752083, states[0] = -94.780273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2076709169, states[0] = -94.716855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2084800069, states[0] = -94.825103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2092868773, states[0] = -94.861293, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.765015
 - CaMKt in component CaMK (millimolar): 0.006848
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.777685
 - nass in component intracellular_ions (millimolar): 6.777744
 - ki in component intracellular_ions (millimolar): 145.199419
 - kss in component intracellular_ions (millimolar): 145.199400
 - cansr in component intracellular_ions (millimolar): 1.314985
 - cajsr in component intracellular_ions (millimolar): 1.278006
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003669
 - hf in component INa (dimensionless): 0.877606
 - hs in component INa (dimensionless): 0.877602
 - j in component INa (dimensionless): 0.877575
 - hsp in component INa (dimensionless): 0.721336
 - jp in component INa (dimensionless): 0.877556
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.708228
 - hLp in component INaL (dimensionless): 0.453825
 - a in component Ito (dimensionless): 0.000629
 - iF in component Ito (dimensionless): 0.999866
 - iS in component Ito (dimensionless): 0.628841
 - ap in component Ito (dimensionless): 0.000321
 - iFp in component Ito (dimensionless): 0.999866
 - iSp in component Ito (dimensionless): 0.705149
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.940394
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999903
 - jca in component ICaL (dimensionless): 0.999982
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001624
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.327431
 - xs1 in component IKs (dimensionless): 0.227630
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997373
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:31:56 (59691): called boinc_finish(0)


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141042538093_ORdGradInc_k_25-Pueyo_APDR-conf_241.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141042538093_ORdGradInc_k_25-Pueyo_APDR-conf_241_0_r749521355_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141042538093_ORdGradInc_k_25-Pueyo_APDR-conf_241_0_r749521355_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 107.303843
     * GNaL_b in INaL: 0.005225
     * Gto_b in Ito: 0.076554
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033382
     * GKs_b in IKs: 0.001779
     * GK1_b in IK1: 0.165021
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 65.952836
     * GKb_b in IKb: 0.003862
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 2092868773
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.861293 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading resultsTime...
Loading resultsAPD90...
Loading resultsAPD75...
Loading resultsAPD50...
Loading resultsAPD25...
Loading resultsAPD10...
Loading resultsTriangulation...
Loading resultsMaxV...
Loading resultsMinV...
Loading resultsMaxDiffV...
Loading resultsMinDiffV...
Copy resultsTime...
Copy resultsAPD90...
Copy resultsAPD75...
Copy resultsAPD50...
Copy resultsAPD25...
Copy resultsAPD10...
Copy resultsTriangulation...
Copy resultsMaxV...
Copy resultsMinV...
Copy resultsMaxDiffV...
Copy resultsMinDiffV...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.765015
 - CaMKt in component CaMK (millimolar): 0.006848
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.777685
 - nass in component intracellular_ions (millimolar): 6.777744
 - ki in component intracellular_ions (millimolar): 145.199419
 - kss in component intracellular_ions (millimolar): 145.199400
 - cansr in component intracellular_ions (millimolar): 1.314985
 - cajsr in component intracellular_ions (millimolar): 1.278006
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003669
 - hf in component INa (dimensionless): 0.877606
 - hs in component INa (dimensionless): 0.877602
 - j in component INa (dimensionless): 0.877575
 - hsp in component INa (dimensionless): 0.721336
 - jp in component INa (dimensionless): 0.877556
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.708228
 - hLp in component INaL (dimensionless): 0.453825
 - a in component Ito (dimensionless): 0.000629
 - iF in component Ito (dimensionless): 0.999866
 - iS in component Ito (dimensionless): 0.628841
 - ap in component Ito (dimensionless): 0.000321
 - iFp in component Ito (dimensionless): 0.999866
 - iSp in component Ito (dimensionless): 0.705149
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.940394
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999903
 - jca in component ICaL (dimensionless): 0.999982
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001624
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.327431
 - xs1 in component IKs (dimensionless): 0.227630
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997373
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:35:52 (62304): called boinc_finish(0)

</stderr_txt>
]]>


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