𝕏

Task 55441291

Name HuVeMOp_20240630141042538093_ORdGradInc_k_25-Pueyo_APDR-conf_937_1
Workunit 26326865
Created 30 Jun 2024, 12:10:57 UTC
Sent 30 Jun 2024, 13:41:00 UTC
Report deadline 3 Jul 2024, 23:17:00 UTC
Received 30 Jun 2024, 21:43:38 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227318
Run time 1 hours 49 min 15 sec
CPU time 1 hours 37 min 55 sec
Validate state Valid
Credit 83.80
Device peak FLOPS 5.60 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.81 MB
Peak swap size 391.90 GB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141042538093_ORdGradInc_k_25-Pueyo_APDR-conf_937.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141042538093_ORdGradInc_k_25-Pueyo_APDR-conf_937_1_r718015558_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630141042538093_ORdGradInc_k_25-Pueyo_APDR-conf_937_1_r718015558_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 91.235490
     * GNaL_b in INaL: 0.005004
     * Gto_b in Ito: 0.095238
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031613
     * GKs_b in IKs: 0.002097
     * GK1_b in IK1: 0.179032
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 67.845819
     * GKb_b in IKb: 0.003842
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.020489
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 18042817, states[0] = 13.230091, states[40]= 0.004777
Saving checkpoint... 
Iteration: 34350866, states[0] = -95.032062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52153445, states[0] = -78.244463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68914417, states[0] = -95.038626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86883800, states[0] = -95.026076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103291738, states[0] = -94.973438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126928378, states[0] = -95.035303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148510435, states[0] = 21.357100, states[40]= 0.045469
Saving checkpoint... 
Iteration: 164086997, states[0] = -7.637626, states[40]= 0.002810
Saving checkpoint... 
Iteration: 180568576, states[0] = 3.608192, states[40]= 0.004526
Saving checkpoint... 
Iteration: 197687995, states[0] = -94.818148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217161454, states[0] = -90.086906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235279719, states[0] = -94.959699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252684896, states[0] = -94.809918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268934576, states[0] = -95.035110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286668068, states[0] = -94.165893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304306092, states[0] = -94.981513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322514558, states[0] = 20.918884, states[40]= 0.017799
Saving checkpoint... 
Iteration: 340764160, states[0] = -94.943577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359167383, states[0] = -94.008022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377967630, states[0] = -95.041127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395766959, states[0] = -94.946592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413275527, states[0] = -94.955428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430024484, states[0] = 19.394223, states[40]= 0.006254
Saving checkpoint... 
Iteration: 446867133, states[0] = -95.014784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464906242, states[0] = -95.027952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483645945, states[0] = -65.162838, states[40]= 0.000002
Saving checkpoint... 
Iteration: 501670255, states[0] = -94.488037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519606804, states[0] = -25.341973, states[40]= 0.000713
Saving checkpoint... 
Iteration: 537000395, states[0] = -46.013964, states[40]= 0.000001
Saving checkpoint... 
Iteration: 555802555, states[0] = -94.978675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572871720, states[0] = -95.016483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591771306, states[0] = -94.951011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610043679, states[0] = 13.621737, states[40]= 0.004756
Saving checkpoint... 
Iteration: 628106307, states[0] = -24.885620, states[40]= 0.000733
Saving checkpoint... 
Iteration: 645581538, states[0] = -3.628198, states[40]= 0.003625
Saving checkpoint... 
Iteration: 663483164, states[0] = -95.043177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681537076, states[0] = 15.877043, states[40]= 0.004915
Saving checkpoint... 
Iteration: 698826796, states[0] = -94.994768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718540609, states[0] = 14.693186, states[40]= 0.004810
Saving checkpoint... 
Iteration: 735901197, states[0] = -95.026277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754043758, states[0] = 13.593803, states[40]= 0.004755
Saving checkpoint... 
Iteration: 772668037, states[0] = -94.158629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790126575, states[0] = -43.979299, states[40]= 0.000076
Saving checkpoint... 
Iteration: 806748995, states[0] = -94.924952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824735392, states[0] = -94.906005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841996726, states[0] = -95.044772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858480915, states[0] = -95.042699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876965349, states[0] = -95.040336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894282162, states[0] = -94.961358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913053750, states[0] = 9.905331, states[40]= 0.004705
Saving checkpoint... 
Iteration: 931470179, states[0] = -95.041054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949429141, states[0] = -95.033308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967090036, states[0] = -10.109737, states[40]= 0.002293
Saving checkpoint... 
Iteration: 986328984, states[0] = -94.995806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004339926, states[0] = -95.001811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021353729, states[0] = -95.008541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039055466, states[0] = 9.237672, states[40]= 0.004701
Saving checkpoint... 
Iteration: 1057348769, states[0] = -95.006189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075013180, states[0] = 21.044417, states[40]= 0.023680
Saving checkpoint... 
Iteration: 1092836261, states[0] = -94.999789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111390466, states[0] = -95.022653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129850557, states[0] = -95.006976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146816267, states[0] = -94.987816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165025010, states[0] = 19.277754, states[40]= 0.006125
Saving checkpoint... 
Iteration: 1182027092, states[0] = 18.785114, states[40]= 0.005727
Saving checkpoint... 
Iteration: 1207532502, states[0] = 17.305029, states[40]= 0.005156
Saving checkpoint... 
Iteration: 1239313330, states[0] = -94.985780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266309303, states[0] = -94.982979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290008556, states[0] = 21.850287, states[40]= 0.073614
Saving checkpoint... 
Iteration: 1316679306, states[0] = -94.785445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350815505, states[0] = -94.987139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379277986, states[0] = -94.957002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406983235, states[0] = -95.042554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432093452, states[0] = -13.099586, states[40]= 0.001743
Saving checkpoint... 
Iteration: 1447059748, states[0] = 7.514922, states[40]= 0.004680
Saving checkpoint... 
Iteration: 1460338695, states[0] = -95.000776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478554328, states[0] = 9.681904, states[40]= 0.004704
Saving checkpoint... 
Iteration: 1514410579, states[0] = 22.293652, states[40]= 0.045006
Saving checkpoint... 
Iteration: 1549298199, states[0] = -34.999136, states[40]= 0.000271
Saving checkpoint... 
Iteration: 1578835721, states[0] = -95.230259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1601659913, states[0] = -95.259637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1616283951, states[0] = -95.145843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628469217, states[0] = -5.460013, states[40]= 0.003701
Saving checkpoint... 
Iteration: 1644159383, states[0] = -95.082194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1663895876, states[0] = -33.307118, states[40]= 0.000332
Saving checkpoint... 
Iteration: 1681800666, states[0] = 38.008248, states[40]= 0.004682
Saving checkpoint... 
Iteration: 1699187231, states[0] = -95.284623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1717590584, states[0] = -27.650925, states[40]= 0.000587
Saving checkpoint... 
Iteration: 1735410532, states[0] = -95.198803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1752936972, states[0] = 13.576935, states[40]= 0.005839
Saving checkpoint... 
Iteration: 1769950693, states[0] = -95.252638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1787948658, states[0] = -95.250436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1806035391, states[0] = 15.733654, states[40]= 0.004820
Saving checkpoint... 
Iteration: 1823772181, states[0] = -94.980269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1841522134, states[0] = 19.678965, states[40]= 0.006970
Saving checkpoint... 
Iteration: 1859741906, states[0] = -94.925082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1878898948, states[0] = -95.030474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1895835113, states[0] = -95.002004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1913567578, states[0] = 4.030595, states[40]= 0.004553
Saving checkpoint... 
Iteration: 1931112902, states[0] = -31.039544, states[40]= 0.000440
Saving checkpoint... 
Iteration: 1947595118, states[0] = -14.651227, states[40]= 0.001507
Saving checkpoint... 
Iteration: 1965390239, states[0] = -95.022233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1982704786, states[0] = -94.852277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2000108870, states[0] = -27.249780, states[40]= 0.000624
Saving checkpoint... 
Iteration: 2017126821, states[0] = -44.231571, states[40]= 0.000073
Saving checkpoint... 
Iteration: 2032942921, states[0] = -95.035293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2049900679, states[0] = -95.024960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067718344, states[0] = -94.877235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2083882059, states[0] = -95.018924, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.919891
 - CaMKt in component CaMK (millimolar): 0.007516
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.685863
 - nass in component intracellular_ions (millimolar): 6.685925
 - ki in component intracellular_ions (millimolar): 145.282017
 - kss in component intracellular_ions (millimolar): 145.281998
 - cansr in component intracellular_ions (millimolar): 1.346222
 - cajsr in component intracellular_ions (millimolar): 1.307619
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003612
 - hf in component INa (dimensionless): 0.880313
 - hs in component INa (dimensionless): 0.880309
 - j in component INa (dimensionless): 0.880280
 - hsp in component INa (dimensionless): 0.726419
 - jp in component INa (dimensionless): 0.880260
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710169
 - hLp in component INaL (dimensionless): 0.451939
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620293
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695598
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937086
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999890
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001728
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.313043
 - xs1 in component IKs (dimensionless): 0.240872
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997332
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:50:09 (46276): called boinc_finish(0)

</stderr_txt>
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