𝕏

Task 55440815

Name HuVeMOp_20240630140100616664_ORdGradInc_k_25-Pueyo_APDR-conf_957_1
Workunit 26326634
Created 30 Jun 2024, 12:01:13 UTC
Sent 30 Jun 2024, 13:41:00 UTC
Report deadline 3 Jul 2024, 23:17:00 UTC
Received 30 Jun 2024, 21:43:38 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227318
Run time 1 hours 47 min 34 sec
CPU time 1 hours 36 min 39 sec
Validate state Valid
Credit 66.18
Device peak FLOPS 5.60 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.63 MB
Peak swap size 391.77 GB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630140100616664_ORdGradInc_k_25-Pueyo_APDR-conf_957.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630140100616664_ORdGradInc_k_25-Pueyo_APDR-conf_957_1_r386523431_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630140100616664_ORdGradInc_k_25-Pueyo_APDR-conf_957_1_r386523431_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 117.637989
     * GNaL_b in INaL: 0.006732
     * Gto_b in Ito: 0.096440
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.030052
     * GKs_b in IKs: 0.001807
     * GK1_b in IK1: 0.172395
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 68.926115
     * GKb_b in IKb: 0.003938
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.045012
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 17694244, states[0] = -94.901311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34738353, states[0] = -94.949452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51855242, states[0] = -95.034016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68806894, states[0] = -95.000398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86440424, states[0] = -95.049036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103724722, states[0] = -94.903120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121256405, states[0] = -94.945967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138905061, states[0] = -95.036312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157345849, states[0] = -95.014116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175092237, states[0] = -8.339451, states[40]= 0.002641
Saving checkpoint... 
Iteration: 192916319, states[0] = -95.038227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211123650, states[0] = -35.589606, states[40]= 0.000270
Saving checkpoint... 
Iteration: 228545974, states[0] = 13.877182, states[40]= 0.004862
Saving checkpoint... 
Iteration: 245670622, states[0] = -92.642759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262937430, states[0] = -95.042659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281252415, states[0] = -94.938968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298441953, states[0] = -95.043504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317081029, states[0] = -0.847301, states[40]= 0.004067
Saving checkpoint... 
Iteration: 335498586, states[0] = -95.051927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352422728, states[0] = -95.039393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370691741, states[0] = -94.836677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388023336, states[0] = 20.339399, states[40]= 0.007159
Saving checkpoint... 
Iteration: 405585833, states[0] = -3.753850, states[40]= 0.003585
Saving checkpoint... 
Iteration: 423194402, states[0] = -94.843172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440970907, states[0] = -95.048275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458854922, states[0] = -95.017366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475882926, states[0] = -95.028149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493825644, states[0] = -95.002435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510337636, states[0] = -95.009049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528302531, states[0] = -94.987173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546827522, states[0] = -95.003486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565859140, states[0] = -95.019104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583411649, states[0] = -95.036524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601897628, states[0] = -95.032669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619970181, states[0] = -95.048036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637944934, states[0] = -95.043810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655687463, states[0] = -94.821228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673703394, states[0] = -94.861345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691543205, states[0] = 14.819163, states[40]= 0.004913
Saving checkpoint... 
Iteration: 708530630, states[0] = 18.657249, states[40]= 0.005626
Saving checkpoint... 
Iteration: 732406533, states[0] = -95.035071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760899285, states[0] = -95.033033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787956941, states[0] = -95.045828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813715509, states[0] = -94.883528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841158618, states[0] = -74.679844, states[40]= 0.000001
Saving checkpoint... 
Iteration: 873662462, states[0] = -81.401748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904392698, states[0] = -95.030970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930625206, states[0] = -36.997285, states[40]= 0.000223
Saving checkpoint... 
Iteration: 953808658, states[0] = -94.991248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967677180, states[0] = -94.541754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981271849, states[0] = -94.960211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999924076, states[0] = -95.039223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035824076, states[0] = -95.001108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072427585, states[0] = -95.039956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102383642, states[0] = -95.027926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127661490, states[0] = -79.634182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142980422, states[0] = -95.049093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155189596, states[0] = -94.829597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170880603, states[0] = -95.026846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190980145, states[0] = -95.049020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210838554, states[0] = -95.009007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228200116, states[0] = -94.854534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245561779, states[0] = 8.087502, states[40]= 0.004745
Saving checkpoint... 
Iteration: 1263615683, states[0] = -28.488724, states[40]= 0.000603
Saving checkpoint... 
Iteration: 1281490174, states[0] = -95.050239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299920994, states[0] = -95.038288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317369309, states[0] = -95.022639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334600905, states[0] = -15.559742, states[40]= 0.001385
Saving checkpoint... 
Iteration: 1352909049, states[0] = -95.035282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371633099, states[0] = -44.510030, states[40]= 0.000075
Saving checkpoint... 
Iteration: 1388426980, states[0] = -95.039589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405639081, states[0] = -50.628660, states[40]= 0.000029
Saving checkpoint... 
Iteration: 1423630538, states[0] = -42.003419, states[40]= 0.000109
Saving checkpoint... 
Iteration: 1440198411, states[0] = -94.850954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457595442, states[0] = -10.891657, states[40]= 0.002122
Saving checkpoint... 
Iteration: 1475545940, states[0] = 13.890601, states[40]= 0.004862
Saving checkpoint... 
Iteration: 1493858401, states[0] = -95.018106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1511459826, states[0] = 4.284805, states[40]= 0.005160
Saving checkpoint... 
Iteration: 1529754488, states[0] = 6.663323, states[40]= 0.005392
Saving checkpoint... 
Iteration: 1547734046, states[0] = 15.945347, states[40]= 0.006310
Saving checkpoint... 
Iteration: 1564171134, states[0] = -95.285730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1580467585, states[0] = -1.645131, states[40]= 0.004492
Saving checkpoint... 
Iteration: 1597913081, states[0] = -46.744812, states[40]= 0.000055
Saving checkpoint... 
Iteration: 1616574675, states[0] = -95.149009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1633035883, states[0] = -78.305453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1651089100, states[0] = -95.182406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1669025288, states[0] = -61.817313, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1686798745, states[0] = -95.201758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1704948268, states[0] = 9.268906, states[40]= 0.005587
Saving checkpoint... 
Iteration: 1723068978, states[0] = -95.135934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1740200275, states[0] = -95.204682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1758461930, states[0] = -95.110467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1775625799, states[0] = -95.245530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1792966374, states[0] = -95.128274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1810452006, states[0] = -95.089619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1828948321, states[0] = -95.071388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846825009, states[0] = -95.017581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1864489083, states[0] = -95.059344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1882424066, states[0] = -95.044211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1899538028, states[0] = 16.450124, states[40]= 0.005083
Saving checkpoint... 
Iteration: 1917074996, states[0] = 2.258518, states[40]= 0.004431
Saving checkpoint... 
Iteration: 1934893710, states[0] = -95.031656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1952402508, states[0] = -95.033717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1968707006, states[0] = -94.867620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1987328335, states[0] = -95.003075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2003413036, states[0] = -95.035919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2021259725, states[0] = -94.946394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2049043435, states[0] = 14.741613, states[40]= 0.004908
Saving checkpoint... 
Iteration: 2087841479, states[0] = -95.009790, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.926596
 - CaMKt in component CaMK (millimolar): 0.007458
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.660996
 - nass in component intracellular_ions (millimolar): 6.661056
 - ki in component intracellular_ions (millimolar): 145.310619
 - kss in component intracellular_ions (millimolar): 145.310599
 - cansr in component intracellular_ions (millimolar): 1.335007
 - cajsr in component intracellular_ions (millimolar): 1.295860
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003609
 - hf in component INa (dimensionless): 0.880429
 - hs in component INa (dimensionless): 0.880425
 - j in component INa (dimensionless): 0.880397
 - hsp in component INa (dimensionless): 0.726640
 - jp in component INa (dimensionless): 0.880379
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.708848
 - hLp in component INaL (dimensionless): 0.447715
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.613862
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.687654
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.931852
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999869
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001684
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.338901
 - xs1 in component IKs (dimensionless): 0.251744
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997331
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:23:34 (47099): called boinc_finish(0)

</stderr_txt>
]]>


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