𝕏

Task 55440734

Name HuVeMOp_20240630140100616664_ORdGradInc_k_25-Pueyo_APDR-conf_635_0
Workunit 26326594
Created 30 Jun 2024, 12:01:13 UTC
Sent 30 Jun 2024, 13:48:13 UTC
Report deadline 3 Jul 2024, 23:24:13 UTC
Received 1 Jul 2024, 6:39:27 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230980
Run time 8 hours 36 min 14 sec
CPU time 8 hours 36 min 14 sec
Validate state Valid
Credit 61.79
Device peak FLOPS 1.23 GFLOPS
Application version Human ventricular cell models optimization v0.02
aarch64-unknown-linux-gnu
Peak working set size 2.23 MB
Peak swap size 11.08 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630140100616664_ORdGradInc_k_25-Pueyo_APDR-conf_635.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630140100616664_ORdGradInc_k_25-Pueyo_APDR-conf_635_0_r1060991310_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630140100616664_ORdGradInc_k_25-Pueyo_APDR-conf_635_0_r1060991310_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 113.984616
     * GNaL_b in INaL: 0.005356
     * Gto_b in Ito: 0.076052
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033111
     * GKs_b in IKs: 0.002135
     * GK1_b in IK1: 0.175301
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.571591
     * GKb_b in IKb: 0.003883
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025859
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12342702, states[0] = -95.175905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24681314, states[0] = -94.968892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37029061, states[0] = 18.182105, states[40]= 0.006723
Saving checkpoint... 
Iteration: 49379756, states[0] = -95.132772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61735124, states[0] = -95.024233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74090854, states[0] = -16.971072, states[40]= 0.001259
Saving checkpoint... 
Iteration: 86429178, states[0] = -95.130402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98743963, states[0] = -95.024884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111116355, states[0] = -42.720664, states[40]= 0.000082
Saving checkpoint... 
Iteration: 123523240, states[0] = 20.429001, states[40]= 0.008454
Saving checkpoint... 
Iteration: 135764385, states[0] = -95.043853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147981371, states[0] = -95.132676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160216701, states[0] = -94.982162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172427197, states[0] = -95.123140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184707761, states[0] = -94.966749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196930478, states[0] = -95.123497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209143159, states[0] = -77.011365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221353824, states[0] = -95.100781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233563356, states[0] = 4.215884, states[40]= 0.004835
Saving checkpoint... 
Iteration: 245772632, states[0] = -95.049932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257983309, states[0] = -95.131695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270243884, states[0] = -95.019470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282555217, states[0] = 8.087762, states[40]= 0.005074
Saving checkpoint... 
Iteration: 294863234, states[0] = -95.104320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307152360, states[0] = -91.854168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319398312, states[0] = -95.115572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331607281, states[0] = -32.933705, states[40]= 0.000319
Saving checkpoint... 
Iteration: 343820499, states[0] = -95.084433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356028244, states[0] = 18.899975, states[40]= 0.006910
Saving checkpoint... 
Iteration: 368252855, states[0] = -95.029848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380488427, states[0] = -95.132201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392724235, states[0] = -94.992808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404941477, states[0] = -95.125210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417153674, states[0] = -92.833382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429365802, states[0] = -95.105184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441574290, states[0] = -2.032113, states[40]= 0.004075
Saving checkpoint... 
Iteration: 453794809, states[0] = -95.067835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466085898, states[0] = -11.410896, states[40]= 0.002127
Saving checkpoint... 
Iteration: 478377405, states[0] = -95.109201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490613882, states[0] = -39.787787, states[40]= 0.000127
Saving checkpoint... 
Iteration: 502969674, states[0] = -95.129701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515222344, states[0] = -94.989894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527428521, states[0] = -95.122622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539636048, states[0] = -65.808728, states[40]= 0.000002
Saving checkpoint... 
Iteration: 551844863, states[0] = -95.096604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564053089, states[0] = 9.040535, states[40]= 0.005124
Saving checkpoint... 
Iteration: 576263610, states[0] = -95.041073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588477308, states[0] = -95.130694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600691126, states[0] = -94.934985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612902052, states[0] = -95.116399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625116984, states[0] = -43.117475, states[40]= 0.000078
Saving checkpoint... 
Iteration: 637352086, states[0] = -95.099683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649649387, states[0] = -88.273302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661946462, states[0] = -95.125957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674229054, states[0] = -94.999657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686469051, states[0] = -95.129510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698689428, states[0] = -94.931528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710905492, states[0] = -95.117234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723136001, states[0] = -65.743974, states[40]= 0.000002
Saving checkpoint... 
Iteration: 735353336, states[0] = -95.100148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747587037, states[0] = -12.500459, states[40]= 0.001920
Saving checkpoint... 
Iteration: 759823795, states[0] = -95.086031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772056370, states[0] = 7.563966, states[40]= 0.005046
Saving checkpoint... 
Iteration: 784290040, states[0] = -95.064091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796510455, states[0] = 24.005054, states[40]= 0.048981
Saving checkpoint... 
Iteration: 808741903, states[0] = -95.016687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820958853, states[0] = -95.127916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833232845, states[0] = -95.004848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845535677, states[0] = 16.242871, states[40]= 0.005900
Saving checkpoint... 
Iteration: 857815628, states[0] = -95.081316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870035436, states[0] = 16.334353, states[40]= 0.005922
Saving checkpoint... 
Iteration: 882246703, states[0] = -95.022483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894460815, states[0] = -95.128178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906675730, states[0] = -94.901710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918895955, states[0] = -95.114579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931109229, states[0] = -34.933368, states[40]= 0.000248
Saving checkpoint... 
Iteration: 943323695, states[0] = -95.085873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955551213, states[0] = 9.864946, states[40]= 0.005169
Saving checkpoint... 
Iteration: 967765235, states[0] = -95.042461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979976806, states[0] = -95.130408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992197210, states[0] = -94.946618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004434867, states[0] = -95.123626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016738065, states[0] = -95.011692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029043128, states[0] = 13.284496, states[40]= 0.005428
Saving checkpoint... 
Iteration: 1041355731, states[0] = -95.100956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053567977, states[0] = 1.780440, states[40]= 0.004609
Saving checkpoint... 
Iteration: 1065778706, states[0] = -95.054762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078005775, states[0] = 28.515454, states[40]= 0.127615
Saving checkpoint... 
Iteration: 1090232950, states[0] = -95.004846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102454758, states[0] = -95.127107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114661595, states[0] = -94.724450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126871200, states[0] = -95.106728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139083739, states[0] = -9.411713, states[40]= 0.002539
Saving checkpoint... 
Iteration: 1151289134, states[0] = -95.063189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163496905, states[0] = -95.132726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175711758, states[0] = -94.972601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187932804, states[0] = -95.123117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200205391, states[0] = -94.961574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212509455, states[0] = 24.487547, states[40]= 0.061199
Saving checkpoint... 
Iteration: 1224797601, states[0] = -95.069407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237011203, states[0] = 23.711426, states[40]= 0.041579
Saving checkpoint... 
Iteration: 1249213684, states[0] = -94.975767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261417966, states[0] = -95.119926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273640199, states[0] = -71.941374, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1285848810, states[0] = -95.097927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298060838, states[0] = 5.462947, states[40]= 0.004924
Saving checkpoint... 
Iteration: 1310272155, states[0] = -95.048826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322486283, states[0] = -95.131414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334704345, states[0] = -94.959628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346913122, states[0] = -95.118753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359126119, states[0] = -53.445413, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1371350261, states[0] = -95.098501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383647039, states[0] = -84.243407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395946066, states[0] = -95.125476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408227246, states[0] = -94.996652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420435306, states[0] = -95.123477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432646360, states[0] = -82.971459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444859261, states[0] = -95.102132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457074602, states[0] = -2.239606, states[40]= 0.004039
Saving checkpoint... 
Iteration: 1469281116, states[0] = -95.056573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481488961, states[0] = -95.131644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493692374, states[0] = -94.936954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1505869473, states[0] = -95.183499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1518003028, states[0] = 40.426767, states[40]= 0.089159
Saving checkpoint... 
Iteration: 1530097299, states[0] = -39.305553, states[40]= 0.000139
Saving checkpoint... 
Iteration: 1542194156, states[0] = -95.260238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1554341354, states[0] = 11.232078, states[40]= 0.006241
Saving checkpoint... 
Iteration: 1566549218, states[0] = -95.343703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1578742810, states[0] = -95.078699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1590903048, states[0] = 40.081749, states[40]= 0.096707
Saving checkpoint... 
Iteration: 1602989979, states[0] = -32.252184, states[40]= 0.000346
Saving checkpoint... 
Iteration: 1615089968, states[0] = -95.268432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1627197058, states[0] = -95.387108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1639305096, states[0] = -50.705137, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1651459528, states[0] = -95.360649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1663594499, states[0] = -37.672401, states[40]= 0.000175
Saving checkpoint... 
Iteration: 1675824297, states[0] = 19.220200, states[40]= 0.009184
Saving checkpoint... 
Iteration: 1687980149, states[0] = -95.250491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1700125671, states[0] = 18.641636, states[40]= 0.008664
Saving checkpoint... 
Iteration: 1712275284, states[0] = -95.240175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1724418253, states[0] = 21.568757, states[40]= 0.014152
Saving checkpoint... 
Iteration: 1736615584, states[0] = -95.311842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1748861630, states[0] = -95.208133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1761097129, states[0] = -40.827729, states[40]= 0.000112
Saving checkpoint... 
Iteration: 1773294388, states[0] = -95.386506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1785550008, states[0] = -95.352296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1797818861, states[0] = -95.316374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1810006689, states[0] = 26.670873, states[40]= 0.114295
Saving checkpoint... 
Iteration: 1822167140, states[0] = -94.904996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1834323289, states[0] = -95.107778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846484212, states[0] = -95.146631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1858641268, states[0] = -75.227152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1870799203, states[0] = -95.077896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1882958080, states[0] = -95.132533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1895103521, states[0] = -29.365199, states[40]= 0.000470
Saving checkpoint... 
Iteration: 1907253061, states[0] = -95.031847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919454476, states[0] = -95.128398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931691096, states[0] = -94.935449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1943917572, states[0] = -95.120307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1956168004, states[0] = -94.869947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1968479594, states[0] = -95.130609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1980781555, states[0] = -95.056915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1993079841, states[0] = -6.093798, states[40]= 0.003269
Saving checkpoint... 
Iteration: 2005382168, states[0] = -95.109984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2017681906, states[0] = -94.915254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2029979837, states[0] = -95.130240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2042279768, states[0] = -95.055122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2054579765, states[0] = -6.024083, states[40]= 0.003284
Saving checkpoint... 
Iteration: 2066877997, states[0] = -95.108482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2079177674, states[0] = -94.905734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2091480563, states[0] = -95.130238, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.008373
 - CaMKt in component CaMK (millimolar): 0.006692
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.564747
 - nass in component intracellular_ions (millimolar): 6.564808
 - ki in component intracellular_ions (millimolar): 145.415330
 - kss in component intracellular_ions (millimolar): 145.415310
 - cansr in component intracellular_ions (millimolar): 1.303825
 - cajsr in component intracellular_ions (millimolar): 1.266891
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003580
 - hf in component INa (dimensionless): 0.881837
 - hs in component INa (dimensionless): 0.881833
 - j in component INa (dimensionless): 0.881807
 - hsp in component INa (dimensionless): 0.729302
 - jp in component INa (dimensionless): 0.881789
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.714883
 - hLp in component INaL (dimensionless): 0.461922
 - a in component Ito (dimensionless): 0.000619
 - iF in component Ito (dimensionless): 0.999872
 - iS in component Ito (dimensionless): 0.630771
 - ap in component Ito (dimensionless): 0.000315
 - iFp in component Ito (dimensionless): 0.999872
 - iSp in component Ito (dimensionless): 0.707499
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.939313
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999901
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001584
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329612
 - xs1 in component IKs (dimensionless): 0.229390
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997309
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
06:39:04 (832119): called boinc_finish(0)

</stderr_txt>
]]>


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