𝕏

Task 55440591

Name HuVeMOp_20240630140100616664_ORdGradInc_k_25-Pueyo_APDR-conf_819_1
Workunit 26326522
Created 30 Jun 2024, 12:01:08 UTC
Sent 30 Jun 2024, 13:37:26 UTC
Report deadline 3 Jul 2024, 23:13:26 UTC
Received 1 Jul 2024, 13:55:53 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 229770
Run time 1 hours 21 min
CPU time 1 hours 12 min 11 sec
Validate state Valid
Credit 60.50
Device peak FLOPS 4.71 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 6.77 MB
Peak swap size 1.48 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630140100616664_ORdGradInc_k_25-Pueyo_APDR-conf_819.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630140100616664_ORdGradInc_k_25-Pueyo_APDR-conf_819_1_r338230213_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630140100616664_ORdGradInc_k_25-Pueyo_APDR-conf_819_1_r338230213_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 115.935852
     * GNaL_b in INaL: 0.006994
     * Gto_b in Ito: 0.078710
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.029895
     * GKs_b in IKs: 0.002045
     * GK1_b in IK1: 0.164231
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 67.855868
     * GKb_b in IKb: 0.003668
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.020206
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15274924, states[0] = -94.976714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36177422, states[0] = -94.627183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58032916, states[0] = 18.894094, states[40]= 0.005963
Saving checkpoint... 
Iteration: 79897573, states[0] = -94.995015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101277789, states[0] = -94.919029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122715100, states[0] = -94.827698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144284007, states[0] = -94.922146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159657665, states[0] = -73.308297, states[40]= 0.000001
Saving checkpoint... 
Iteration: 181398814, states[0] = -94.987864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203110012, states[0] = -23.608506, states[40]= 0.000844
Saving checkpoint... 
Iteration: 224953808, states[0] = -95.001289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245753035, states[0] = -94.885754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267628185, states[0] = -40.008483, states[40]= 0.000146
Saving checkpoint... 
Iteration: 289416937, states[0] = -94.992722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310487442, states[0] = -95.006662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331749405, states[0] = -94.880754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352725806, states[0] = -94.844418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374290123, states[0] = -94.926505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395564510, states[0] = 7.348629, states[40]= 0.004932
Saving checkpoint... 
Iteration: 417110503, states[0] = -24.028725, states[40]= 0.000825
Saving checkpoint... 
Iteration: 438596159, states[0] = -11.423898, states[40]= 0.002067
Saving checkpoint... 
Iteration: 459666645, states[0] = -88.000555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474593677, states[0] = -9.372049, states[40]= 0.002481
Saving checkpoint... 
Iteration: 495999661, states[0] = -95.008152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516968112, states[0] = -95.003558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538419651, states[0] = -94.993273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559574884, states[0] = 2.595876, states[40]= 0.004607
Saving checkpoint... 
Iteration: 574453802, states[0] = -95.000954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595835936, states[0] = -94.959825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616886436, states[0] = -94.982991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638308273, states[0] = -94.941428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659263233, states[0] = -94.898244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680537880, states[0] = 17.471097, states[40]= 0.005557
Saving checkpoint... 
Iteration: 701778487, states[0] = -94.915078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722742601, states[0] = -94.870862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744219787, states[0] = -94.833592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765233079, states[0] = -94.856224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786531154, states[0] = 19.634281, states[40]= 0.006179
Saving checkpoint... 
Iteration: 807888180, states[0] = -94.983493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828826717, states[0] = -94.954102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850270819, states[0] = -94.906836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871337337, states[0] = -94.960460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892840248, states[0] = -94.962085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914145267, states[0] = -57.611540, states[40]= 0.000009
Saving checkpoint... 
Iteration: 935084847, states[0] = -2.985694, states[40]= 0.003824
Saving checkpoint... 
Iteration: 956436092, states[0] = -94.997028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971136697, states[0] = -48.454546, states[40]= 0.000040
Saving checkpoint... 
Iteration: 992360363, states[0] = -94.972177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013793761, states[0] = -94.929356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034585909, states[0] = -3.672258, states[40]= 0.003694
Saving checkpoint... 
Iteration: 1055991790, states[0] = -95.006790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077006383, states[0] = 27.583767, states[40]= 0.119535
Saving checkpoint... 
Iteration: 1098353840, states[0] = -94.969030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119603082, states[0] = -17.459283, states[40]= 0.001208
Saving checkpoint... 
Iteration: 1140605499, states[0] = -19.602281, states[40]= 0.001042
Saving checkpoint... 
Iteration: 1161879656, states[0] = -94.980148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183027496, states[0] = 20.688432, states[40]= 0.006792
Saving checkpoint... 
Iteration: 1204204502, states[0] = -94.804133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225635756, states[0] = -47.484885, states[40]= 0.000047
Saving checkpoint... 
Iteration: 1246633947, states[0] = -45.644288, states[40]= 0.000063
Saving checkpoint... 
Iteration: 1268126158, states[0] = -38.099076, states[40]= 0.000192
Saving checkpoint... 
Iteration: 1289276449, states[0] = -94.912610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310695043, states[0] = -94.783633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331998317, states[0] = -95.007469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353015877, states[0] = 23.291695, states[40]= 0.016763
Saving checkpoint... 
Iteration: 1374405624, states[0] = -94.988818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395576805, states[0] = 1.619311, states[40]= 0.004506
Saving checkpoint... 
Iteration: 1416568250, states[0] = 5.719578, states[40]= 0.004847
Saving checkpoint... 
Iteration: 1437710137, states[0] = -94.815115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458678356, states[0] = -94.505518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479764399, states[0] = -94.899119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495718849, states[0] = -94.831429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1516699459, states[0] = -95.121268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537917701, states[0] = -50.172370, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1559404422, states[0] = 33.641909, states[40]= 0.125390
Saving checkpoint... 
Iteration: 1580708724, states[0] = 26.283967, states[40]= 0.070764
Saving checkpoint... 
Iteration: 1602030161, states[0] = 18.333056, states[40]= 0.007373
Saving checkpoint... 
Iteration: 1616826109, states[0] = -61.913450, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1637828135, states[0] = -64.669490, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1659292580, states[0] = -95.275235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1680255849, states[0] = -95.243123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1701591930, states[0] = -95.275067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1722591028, states[0] = -95.274452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1743613688, states[0] = 24.022849, states[40]= 0.026261
Saving checkpoint... 
Iteration: 1764835263, states[0] = -95.218674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1784216761, states[0] = -50.575579, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1805195264, states[0] = -94.826525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1826370831, states[0] = -95.006737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1847567131, states[0] = 5.821150, states[40]= 0.004874
Saving checkpoint... 
Iteration: 1869008285, states[0] = 25.533302, states[40]= 0.080412
Saving checkpoint... 
Iteration: 1890047485, states[0] = 13.967931, states[40]= 0.005189
Saving checkpoint... 
Iteration: 1911343321, states[0] = -94.965707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932670809, states[0] = -92.426337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1953765156, states[0] = -94.900442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1975131345, states[0] = -43.084813, states[40]= 0.000092
Saving checkpoint... 
Iteration: 1996007044, states[0] = 26.711378, states[40]= 0.105098
Saving checkpoint... 
Iteration: 2017396130, states[0] = -94.985520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2038548172, states[0] = 13.794078, states[40]= 0.005172
Saving checkpoint... 
Iteration: 2059540862, states[0] = 16.441731, states[40]= 0.005397
Saving checkpoint... 
Iteration: 2080858830, states[0] = -94.970768, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.883044
 - CaMKt in component CaMK (millimolar): 0.007188
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.654783
 - nass in component intracellular_ions (millimolar): 6.654844
 - ki in component intracellular_ions (millimolar): 145.320040
 - kss in component intracellular_ions (millimolar): 145.320020
 - cansr in component intracellular_ions (millimolar): 1.326419
 - cajsr in component intracellular_ions (millimolar): 1.287692
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003625
 - hf in component INa (dimensionless): 0.879674
 - hs in component INa (dimensionless): 0.879669
 - j in component INa (dimensionless): 0.879638
 - hsp in component INa (dimensionless): 0.725213
 - jp in component INa (dimensionless): 0.879617
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.707609
 - hLp in component INaL (dimensionless): 0.446180
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.613558
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.686638
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.928679
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999861
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001675
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.351556
 - xs1 in component IKs (dimensionless): 0.253590
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997342
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:54:42 (14116): called boinc_finish(0)

</stderr_txt>
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