𝕏

Task 55439659

Name HuVeMOp_20240630135059965188_ORdGradInc_k_25-Pueyo_APDR-conf_370_1
Workunit 26326105
Created 30 Jun 2024, 11:51:18 UTC
Sent 30 Jun 2024, 13:30:22 UTC
Report deadline 3 Jul 2024, 23:06:22 UTC
Received 30 Jun 2024, 23:25:52 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 190372
Run time 2 hours 51 min 19 sec
CPU time 2 hours 50 min 36 sec
Validate state Valid
Credit 62.86
Device peak FLOPS 3.05 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 4.53 MB
Peak swap size 1.90 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630135059965188_ORdGradInc_k_25-Pueyo_APDR-conf_370.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630135059965188_ORdGradInc_k_25-Pueyo_APDR-conf_370_1_r210711257_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630135059965188_ORdGradInc_k_25-Pueyo_APDR-conf_370_1_r210711257_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 92.398091
     * GNaL_b in INaL: 0.005890
     * Gto_b in Ito: 0.080244
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032972
     * GKs_b in IKs: 0.001907
     * GK1_b in IK1: 0.147961
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.122158
     * GKb_b in IKb: 0.003813
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.039123
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12096503, states[0] = -21.166992, states[40]= 0.000864
Saving checkpoint... 
Iteration: 24522593, states[0] = 20.306195, states[40]= 0.007878
Saving checkpoint... 
Iteration: 36720678, states[0] = -94.807813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49178318, states[0] = -94.678536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59989958, states[0] = -94.958490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72202512, states[0] = -94.743233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84649960, states[0] = -74.964126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96847791, states[0] = -94.904605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109123182, states[0] = -43.565536, states[40]= 0.000074
Saving checkpoint... 
Iteration: 121193707, states[0] = -94.712722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133344163, states[0] = -94.898137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145490169, states[0] = -94.939676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157634295, states[0] = -55.238692, states[40]= 0.000011
Saving checkpoint... 
Iteration: 169772417, states[0] = -94.840401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181909362, states[0] = -94.922300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194278576, states[0] = -94.846531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206417587, states[0] = -94.924266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218519657, states[0] = 21.480058, states[40]= 0.009866
Saving checkpoint... 
Iteration: 231440748, states[0] = -94.929645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243584729, states[0] = -6.698351, states[40]= 0.003041
Saving checkpoint... 
Iteration: 255720979, states[0] = -94.765246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267861340, states[0] = -94.904201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279999313, states[0] = -94.939114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292143305, states[0] = -65.381256, states[40]= 0.000002
Saving checkpoint... 
Iteration: 304286766, states[0] = -94.854187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316434147, states[0] = -94.928006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328581401, states[0] = -4.207359, states[40]= 0.003558
Saving checkpoint... 
Iteration: 340701212, states[0] = -94.725802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352838055, states[0] = -94.892232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364979694, states[0] = -94.936392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377129782, states[0] = -50.268866, states[40]= 0.000026
Saving checkpoint... 
Iteration: 389269428, states[0] = -94.836082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401413965, states[0] = -94.922875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413558736, states[0] = 7.863708, states[40]= 0.004859
Saving checkpoint... 
Iteration: 425698073, states[0] = -94.718938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437848706, states[0] = -94.897937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449986851, states[0] = -94.937356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462132105, states[0] = -52.779342, states[40]= 0.000017
Saving checkpoint... 
Iteration: 474278982, states[0] = -94.846359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486418786, states[0] = -94.924119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498520642, states[0] = 21.270198, states[40]= 0.009073
Saving checkpoint... 
Iteration: 510659551, states[0] = -88.467346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522771027, states[0] = -94.837795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534913979, states[0] = -94.922792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547057128, states[0] = 8.550057, states[40]= 0.004883
Saving checkpoint... 
Iteration: 559203864, states[0] = -94.731274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571355561, states[0] = -94.901257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583494363, states[0] = -94.938268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596436558, states[0] = -94.928358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608565576, states[0] = 4.786295, states[40]= 0.004711
Saving checkpoint... 
Iteration: 620371513, states[0] = -94.908332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632375063, states[0] = -94.909763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644627443, states[0] = -47.765026, states[40]= 0.000039
Saving checkpoint... 
Iteration: 660395130, states[0] = -94.917026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672843982, states[0] = -94.895303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685165703, states[0] = -93.215700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697599415, states[0] = -20.054890, states[40]= 0.000956
Saving checkpoint... 
Iteration: 709551828, states[0] = 10.739138, states[40]= 0.004954
Saving checkpoint... 
Iteration: 721971480, states[0] = -94.934899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734392835, states[0] = -94.916214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746812498, states[0] = -94.875422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759229113, states[0] = -94.779243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771638734, states[0] = -60.080711, states[40]= 0.000005
Saving checkpoint... 
Iteration: 784047838, states[0] = 12.327686, states[40]= 0.005016
Saving checkpoint... 
Iteration: 796462620, states[0] = -94.933374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808883541, states[0] = -94.912896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821297181, states[0] = -94.863234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833712067, states[0] = -94.747814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846131567, states[0] = -52.195722, states[40]= 0.000019
Saving checkpoint... 
Iteration: 858549429, states[0] = 11.699613, states[40]= 0.004989
Saving checkpoint... 
Iteration: 870958672, states[0] = -94.932626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883379018, states[0] = -94.911150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895800449, states[0] = -94.865936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908218071, states[0] = -94.759350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920638147, states[0] = -59.421663, states[40]= 0.000005
Saving checkpoint... 
Iteration: 933051982, states[0] = 10.676945, states[40]= 0.004952
Saving checkpoint... 
Iteration: 945459143, states[0] = -94.932663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957879797, states[0] = -94.911400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969418781, states[0] = -94.923808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981826143, states[0] = -94.884627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994248581, states[0] = -94.809298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006674214, states[0] = -94.531013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019102283, states[0] = -22.812605, states[40]= 0.000796
Saving checkpoint... 
Iteration: 1031517812, states[0] = 21.850262, states[40]= 0.011993
Saving checkpoint... 
Iteration: 1043926826, states[0] = -94.925801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056349485, states[0] = -94.897939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068770602, states[0] = -94.836968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081191044, states[0] = -94.702201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093600966, states[0] = -21.546480, states[40]= 0.000864
Saving checkpoint... 
Iteration: 1105996573, states[0] = -94.938213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118400570, states[0] = -94.918479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130529320, states[0] = 18.969296, states[40]= 0.006156
Saving checkpoint... 
Iteration: 1142709668, states[0] = -94.742829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155118573, states[0] = -38.621411, states[40]= 0.000154
Saving checkpoint... 
Iteration: 1167537078, states[0] = 16.383515, states[40]= 0.005400
Saving checkpoint... 
Iteration: 1179956921, states[0] = -94.932110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192374102, states[0] = -94.909020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204786071, states[0] = -94.852929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217196092, states[0] = -94.714025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229332603, states[0] = -94.888476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241783719, states[0] = -94.850626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254242572, states[0] = -94.800422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266701766, states[0] = -94.726381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278915630, states[0] = -94.922768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291124080, states[0] = -44.225036, states[40]= 0.000067
Saving checkpoint... 
Iteration: 1303327525, states[0] = -94.885300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315714310, states[0] = -94.751897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327872173, states[0] = -94.908150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340019323, states[0] = 21.551151, states[40]= 0.010183
Saving checkpoint... 
Iteration: 1352955888, states[0] = -94.931808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365102744, states[0] = -23.255470, states[40]= 0.000774
Saving checkpoint... 
Iteration: 1377241860, states[0] = -94.799275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389379738, states[0] = -94.911101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400521460, states[0] = 21.086681, states[40]= 0.008539
Saving checkpoint... 
Iteration: 1412564991, states[0] = 5.061709, states[40]= 0.004728
Saving checkpoint... 
Iteration: 1424707546, states[0] = -94.738342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436856521, states[0] = -94.901161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449002919, states[0] = 36.950667, states[40]= 0.137541
Saving checkpoint... 
Iteration: 1461418125, states[0] = -94.923320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473550983, states[0] = 11.079513, states[40]= 0.004966
Saving checkpoint... 
Iteration: 1485693063, states[0] = -94.706872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497841307, states[0] = -94.893317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1509957971, states[0] = 3.673348, states[40]= 0.005156
Saving checkpoint... 
Iteration: 1522067065, states[0] = -95.010202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1534177671, states[0] = -95.207888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1546283348, states[0] = -20.000243, states[40]= 0.001039
Saving checkpoint... 
Iteration: 1558378509, states[0] = -95.069519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1570484326, states[0] = -95.233282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1582593832, states[0] = -32.206650, states[40]= 0.000354
Saving checkpoint... 
Iteration: 1594704370, states[0] = -95.136153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1606818055, states[0] = 21.522858, states[40]= 0.013104
Saving checkpoint... 
Iteration: 1618933652, states[0] = -84.407945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1631044176, states[0] = -95.201012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1643410446, states[0] = 23.839440, states[40]= 0.046582
Saving checkpoint... 
Iteration: 1655513564, states[0] = -55.503129, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1667622088, states[0] = -95.170946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1679732678, states[0] = 15.918538, states[40]= 0.006683
Saving checkpoint... 
Iteration: 1691844798, states[0] = -94.265685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1704741959, states[0] = -93.376845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1716840943, states[0] = -95.198111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1728940530, states[0] = 12.178196, states[40]= 0.006020
Saving checkpoint... 
Iteration: 1741045661, states[0] = -94.428376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1753151378, states[0] = -95.210766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1765258507, states[0] = 2.138812, states[40]= 0.005079
Saving checkpoint... 
Iteration: 1777366480, states[0] = -95.050254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1789479557, states[0] = -95.238445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1801587913, states[0] = -13.065169, states[40]= 0.001847
Saving checkpoint... 
Iteration: 1813694950, states[0] = -94.760504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1825967723, states[0] = -94.971777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1838142268, states[0] = -66.044249, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1850327154, states[0] = -94.903599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1862506175, states[0] = 26.093677, states[40]= 0.121082
Saving checkpoint... 
Iteration: 1874680220, states[0] = -94.667127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1886853695, states[0] = -94.905945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1899106171, states[0] = -26.771897, states[40]= 0.000608
Saving checkpoint... 
Iteration: 1911172998, states[0] = -94.485874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1923250671, states[0] = -94.813832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1935360896, states[0] = -94.904407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1947448979, states[0] = -94.931159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1959559974, states[0] = 7.313809, states[40]= 0.004839
Saving checkpoint... 
Iteration: 1971663733, states[0] = -92.279695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1983770314, states[0] = -94.836392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1995877744, states[0] = -94.910162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2007989643, states[0] = -94.936874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2020103715, states[0] = -24.194758, states[40]= 0.000729
Saving checkpoint... 
Iteration: 2032225624, states[0] = -94.772421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2043812576, states[0] = -94.874659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2055861666, states[0] = -94.903146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067833345, states[0] = -94.888360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2079890085, states[0] = -94.914382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2091926617, states[0] = -94.925040, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.813832
 - CaMKt in component CaMK (millimolar): 0.006890
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.592060
 - nass in component intracellular_ions (millimolar): 6.592120
 - ki in component intracellular_ions (millimolar): 145.386258
 - kss in component intracellular_ions (millimolar): 145.386239
 - cansr in component intracellular_ions (millimolar): 1.308301
 - cajsr in component intracellular_ions (millimolar): 1.270563
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003651
 - hf in component INa (dimensionless): 0.878465
 - hs in component INa (dimensionless): 0.878460
 - j in component INa (dimensionless): 0.878429
 - hsp in component INa (dimensionless): 0.722941
 - jp in component INa (dimensionless): 0.878409
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.707684
 - hLp in component INaL (dimensionless): 0.449600
 - a in component Ito (dimensionless): 0.000627
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.621855
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.696646
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935908
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999889
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001593
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.326762
 - xs1 in component IKs (dimensionless): 0.239296
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997360
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:25:30 (960): called boinc_finish(0)

</stderr_txt>
]]>


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