𝕏

Task 55439425

Name HuVeMOp_20240630135059965188_ORdGradInc_k_25-Pueyo_APDR-conf_927_1
Workunit 26325989
Created 30 Jun 2024, 11:51:08 UTC
Sent 30 Jun 2024, 13:26:54 UTC
Report deadline 3 Jul 2024, 23:02:54 UTC
Received 1 Jul 2024, 1:07:01 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 235804
Run time 1 hours 13 min 25 sec
CPU time 1 hours 9 min 30 sec
Validate state Valid
Credit 60.75
Device peak FLOPS 4.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.26 MB
Peak swap size 5.33 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630135059965188_ORdGradInc_k_25-Pueyo_APDR-conf_927.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630135059965188_ORdGradInc_k_25-Pueyo_APDR-conf_927_1_r1214009704_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630135059965188_ORdGradInc_k_25-Pueyo_APDR-conf_927_1_r1214009704_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 95.496001
     * GNaL_b in INaL: 0.004884
     * Gto_b in Ito: 0.094051
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.031846
     * GKs_b in IKs: 0.002103
     * GK1_b in IK1: 0.164063
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 72.820501
     * GKb_b in IKb: 0.003808
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019252
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13798434, states[0] = -95.047028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32565657, states[0] = 3.638591, states[40]= 0.004554
Saving checkpoint... 
Iteration: 50928539, states[0] = -95.037954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69726612, states[0] = -94.874762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86688581, states[0] = -94.789361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105141450, states[0] = -61.438702, states[40]= 0.000004
Saving checkpoint... 
Iteration: 123454067, states[0] = -95.019898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139825043, states[0] = -94.970389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154091349, states[0] = -11.964212, states[40]= 0.001936
Saving checkpoint... 
Iteration: 171285270, states[0] = -94.937583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189335683, states[0] = -94.975519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207782128, states[0] = -94.933998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227103653, states[0] = -23.341132, states[40]= 0.000780
Saving checkpoint... 
Iteration: 241022084, states[0] = 19.835658, states[40]= 0.007523
Saving checkpoint... 
Iteration: 260125948, states[0] = -44.646745, states[40]= 0.000065
Saving checkpoint... 
Iteration: 267653180, states[0] = -76.674637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286605512, states[0] = -25.074123, states[40]= 0.000700
Saving checkpoint... 
Iteration: 305890454, states[0] = -95.000047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318969894, states[0] = -95.019663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337913228, states[0] = -95.007180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351264755, states[0] = -94.914708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370046837, states[0] = 12.290426, states[40]= 0.004810
Saving checkpoint... 
Iteration: 388762409, states[0] = -94.911852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407677212, states[0] = -94.709933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426544474, states[0] = 13.152357, states[40]= 0.004845
Saving checkpoint... 
Iteration: 445234305, states[0] = -94.872137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463921292, states[0] = -95.009277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482824321, states[0] = -94.967840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501381020, states[0] = -94.996445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520196873, states[0] = -94.799729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539026861, states[0] = 18.759308, states[40]= 0.006076
Saving checkpoint... 
Iteration: 557960648, states[0] = -95.017861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576566434, states[0] = 4.321085, states[40]= 0.004579
Saving checkpoint... 
Iteration: 595486148, states[0] = -95.021969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609202853, states[0] = -94.812785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623233325, states[0] = -94.870406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643530110, states[0] = 17.887561, states[40]= 0.005602
Saving checkpoint... 
Iteration: 664083871, states[0] = -5.746564, states[40]= 0.003204
Saving checkpoint... 
Iteration: 677444846, states[0] = -95.014669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696547853, states[0] = 11.915031, states[40]= 0.004798
Saving checkpoint... 
Iteration: 715874055, states[0] = -94.993540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735902166, states[0] = -95.003585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755699230, states[0] = -94.804799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775827771, states[0] = -94.969841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795433701, states[0] = -95.012104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814742766, states[0] = -94.885012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828571307, states[0] = 1.953802, states[40]= 0.004401
Saving checkpoint... 
Iteration: 848058370, states[0] = 7.824077, states[40]= 0.004717
Saving checkpoint... 
Iteration: 867340443, states[0] = -94.977323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886559829, states[0] = 7.219781, states[40]= 0.004701
Saving checkpoint... 
Iteration: 905932312, states[0] = -95.011694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925119116, states[0] = -37.917066, states[40]= 0.000175
Saving checkpoint... 
Iteration: 944324423, states[0] = -94.967560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963462951, states[0] = -95.017973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982747055, states[0] = -94.891137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002248457, states[0] = -94.893108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022407270, states[0] = -95.004931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042074432, states[0] = 0.292896, states[40]= 0.004224
Saving checkpoint... 
Iteration: 1061357274, states[0] = -94.985883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080929787, states[0] = -95.010958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100470650, states[0] = -95.019196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119632354, states[0] = -51.229088, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1139137502, states[0] = -56.689762, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1158762637, states[0] = -94.911549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177776156, states[0] = -94.926889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197290173, states[0] = -94.940713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216926464, states[0] = -95.010037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236057767, states[0] = 8.070797, states[40]= 0.004723
Saving checkpoint... 
Iteration: 1255327456, states[0] = -94.969282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274749076, states[0] = -94.893770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294207199, states[0] = -94.821433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305004281, states[0] = 28.394032, states[40]= 0.170247
Saving checkpoint... 
Iteration: 1324233700, states[0] = -94.870490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343205498, states[0] = -94.817844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362368594, states[0] = -94.990775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380953917, states[0] = -95.015979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394407406, states[0] = -95.004693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413553147, states[0] = 9.906994, states[40]= 0.004756
Saving checkpoint... 
Iteration: 1432128650, states[0] = -47.391039, states[40]= 0.000042
Saving checkpoint... 
Iteration: 1450967204, states[0] = -95.018352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469771723, states[0] = -94.921866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488668701, states[0] = -94.097186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1507637394, states[0] = -85.102016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1526440733, states[0] = 12.117662, states[40]= 0.005765
Saving checkpoint... 
Iteration: 1545444264, states[0] = -94.113876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564416268, states[0] = -95.200190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1582759741, states[0] = -95.262076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1601762718, states[0] = -0.751611, states[40]= 0.004607
Saving checkpoint... 
Iteration: 1614986873, states[0] = -24.436497, states[40]= 0.000733
Saving checkpoint... 
Iteration: 1633155420, states[0] = -95.261660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1652129690, states[0] = 16.559392, states[40]= 0.006671
Saving checkpoint... 
Iteration: 1665089425, states[0] = -27.292337, states[40]= 0.000582
Saving checkpoint... 
Iteration: 1678271650, states[0] = -8.250267, states[40]= 0.003025
Saving checkpoint... 
Iteration: 1697175569, states[0] = -12.218920, states[40]= 0.002142
Saving checkpoint... 
Iteration: 1715519296, states[0] = -61.686672, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1733936481, states[0] = -95.239747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1752306140, states[0] = 25.246328, states[40]= 0.119835
Saving checkpoint... 
Iteration: 1770793349, states[0] = -95.165984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1789432767, states[0] = -95.234673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807705425, states[0] = -94.864199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1826199547, states[0] = -94.836931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1844552956, states[0] = 9.654685, states[40]= 0.004759
Saving checkpoint... 
Iteration: 1862365983, states[0] = -95.000254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880656485, states[0] = -83.055653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1893587142, states[0] = -8.489150, states[40]= 0.002627
Saving checkpoint... 
Iteration: 1912072356, states[0] = 1.345165, states[40]= 0.004343
Saving checkpoint... 
Iteration: 1924799955, states[0] = -94.950379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1943140362, states[0] = -59.894608, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1961665640, states[0] = -93.154843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1979815066, states[0] = -94.960641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1992552229, states[0] = 10.258169, states[40]= 0.004762
Saving checkpoint... 
Iteration: 2011493187, states[0] = -95.021951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2030292652, states[0] = -94.942346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2048705773, states[0] = -94.817867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067399865, states[0] = -95.001819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2086366552, states[0] = -94.989299, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.898528
 - CaMKt in component CaMK (millimolar): 0.007200
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.516860
 - nass in component intracellular_ions (millimolar): 6.516922
 - ki in component intracellular_ions (millimolar): 145.456452
 - kss in component intracellular_ions (millimolar): 145.456432
 - cansr in component intracellular_ions (millimolar): 1.326139
 - cajsr in component intracellular_ions (millimolar): 1.287854
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003620
 - hf in component INa (dimensionless): 0.879943
 - hs in component INa (dimensionless): 0.879938
 - j in component INa (dimensionless): 0.879907
 - hsp in component INa (dimensionless): 0.725719
 - jp in component INa (dimensionless): 0.879886
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709605
 - hLp in component INaL (dimensionless): 0.451262
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.621029
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.696289
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937798
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999892
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001655
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.317358
 - xs1 in component IKs (dimensionless): 0.239129
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997338
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:57:52 (3908): called boinc_finish(0)

</stderr_txt>
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