𝕏

Task 55438705

Name HuVeMOp_20240630135042667386_ORdGradInc_k_25-Pieske_1000-conf_210_1
Workunit 26325630
Created 30 Jun 2024, 11:50:47 UTC
Sent 30 Jun 2024, 13:26:15 UTC
Report deadline 3 Jul 2024, 13:26:15 UTC
Received 1 Jul 2024, 7:36:38 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 218427
Run time 1 hours 54 min 23 sec
CPU time 1 hours 49 min 43 sec
Validate state Valid
Credit 43.26
Device peak FLOPS 4.19 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.86 MB
Peak swap size 32.57 GB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>7.16.19</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630135042667386_ORdGradInc_k_25-Pieske_1000-conf_210.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630135042667386_ORdGradInc_k_25-Pieske_1000-conf_210_1_r757633294_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630135042667386_ORdGradInc_k_25-Pieske_1000-conf_210_1_r757633294_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 118.336318
     * GNaL_b in INaL: 0.005157
     * Gto_b in Ito: 0.097289
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.031546
     * GKs_b in IKs: 0.002060
     * GK1_b in IK1: 0.155638
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 74.288269
     * GKb_b in IKb: 0.003781
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.024702
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 13968566, states[0] = -86.975439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28011274, states[0] = 21.407222, states[40]= 0.034446
Saving checkpoint... 
Iteration: 41502957, states[0] = 32.295159, states[40]= 0.172373
Saving checkpoint... 
Iteration: 54766780, states[0] = -86.734899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68501331, states[0] = 42.972281, states[40]= 0.071041
Saving checkpoint... 
Iteration: 82473300, states[0] = -86.823608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96458826, states[0] = -86.814555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110469141, states[0] = -86.812323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124368199, states[0] = -86.778973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138408464, states[0] = -86.793036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152372246, states[0] = -86.777886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165963889, states[0] = -86.804925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178854284, states[0] = -86.767666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192149577, states[0] = -74.154792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205932488, states[0] = -86.796948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219686883, states[0] = -86.542245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233439117, states[0] = -86.798316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247252321, states[0] = -86.670737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261057321, states[0] = 8.477251, states[40]= 0.004617
Saving checkpoint... 
Iteration: 274779179, states[0] = -86.705979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288505519, states[0] = 24.326397, states[40]= 0.139823
Saving checkpoint... 
Iteration: 302288797, states[0] = -86.716451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316055375, states[0] = 9.290082, states[40]= 0.004625
Saving checkpoint... 
Iteration: 329826196, states[0] = -86.748937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343418465, states[0] = -86.792562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357189642, states[0] = -86.548804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370965365, states[0] = -86.803560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384741074, states[0] = -86.652735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398478295, states[0] = -86.805781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412226273, states[0] = -86.626408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426031833, states[0] = 18.040502, states[40]= 0.005133
Saving checkpoint... 
Iteration: 439671305, states[0] = -86.392031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453440660, states[0] = -86.798314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467230187, states[0] = -86.633645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480863476, states[0] = -86.771208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494666874, states[0] = -86.125263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508387623, states[0] = -86.781908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521927130, states[0] = -86.794847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535267092, states[0] = -86.690968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548796540, states[0] = -86.723997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562501938, states[0] = 39.329918, states[40]= 0.116057
Saving checkpoint... 
Iteration: 576297983, states[0] = -86.725357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590055295, states[0] = 9.323420, states[40]= 0.004625
Saving checkpoint... 
Iteration: 603795595, states[0] = -86.723037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617583792, states[0] = -6.181803, states[40]= 0.003068
Saving checkpoint... 
Iteration: 631331759, states[0] = -86.752573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645085856, states[0] = -7.878045, states[40]= 0.002717
Saving checkpoint... 
Iteration: 658826660, states[0] = -86.748999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672589457, states[0] = -11.086179, states[40]= 0.002071
Saving checkpoint... 
Iteration: 686289456, states[0] = -86.716807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700044188, states[0] = 13.700124, states[40]= 0.004673
Saving checkpoint... 
Iteration: 713806507, states[0] = -86.733016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727580755, states[0] = -3.891361, states[40]= 0.003515
Saving checkpoint... 
Iteration: 741331728, states[0] = -86.752465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755049644, states[0] = 11.596898, states[40]= 0.004638
Saving checkpoint... 
Iteration: 768804230, states[0] = -86.730962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782606053, states[0] = -27.378778, states[40]= 0.000547
Saving checkpoint... 
Iteration: 796390577, states[0] = -86.782829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810149123, states[0] = -73.506639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823901816, states[0] = -86.786889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836862871, states[0] = -86.770625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850035402, states[0] = 16.874182, states[40]= 0.004912
Saving checkpoint... 
Iteration: 863659410, states[0] = -84.134391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877332901, states[0] = -86.753150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891136657, states[0] = -58.357737, states[40]= 0.000006
Saving checkpoint... 
Iteration: 904848746, states[0] = -86.762985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918614330, states[0] = -35.521284, states[40]= 0.000223
Saving checkpoint... 
Iteration: 932390555, states[0] = -86.782714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946180720, states[0] = -86.520278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959919519, states[0] = -86.792376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973651347, states[0] = -76.428030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987415243, states[0] = -86.791090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001976578, states[0] = -86.805023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015915242, states[0] = -86.791067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029684653, states[0] = -86.534963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043463326, states[0] = -86.802647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057289398, states[0] = -86.716453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071093288, states[0] = -14.751201, states[40]= 0.001462
Saving checkpoint... 
Iteration: 1084904034, states[0] = -86.787438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098662217, states[0] = -85.276482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112439533, states[0] = -86.797528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126063006, states[0] = 5.993953, states[40]= 0.004561
Saving checkpoint... 
Iteration: 1139914915, states[0] = -86.790870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153756303, states[0] = -86.675733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167613643, states[0] = -34.845338, states[40]= 0.000244
Saving checkpoint... 
Iteration: 1181425642, states[0] = -86.793925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195211050, states[0] = -86.595369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208975616, states[0] = -86.804701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222656090, states[0] = -81.765248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236531397, states[0] = 18.176526, states[40]= 0.005168
Saving checkpoint... 
Iteration: 1250348286, states[0] = -86.762447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264078557, states[0] = -2.378987, states[40]= 0.003776
Saving checkpoint... 
Iteration: 1277867772, states[0] = -86.772675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291689554, states[0] = -86.547839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305433180, states[0] = -86.795812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318830945, states[0] = -86.751475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332655292, states[0] = -81.009799, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630135042667386_ORdGradInc_k_25-Pieske_1000-conf_210.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630135042667386_ORdGradInc_k_25-Pieske_1000-conf_210_1_r757633294_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630135042667386_ORdGradInc_k_25-Pieske_1000-conf_210_1_r757633294_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 118.336318
     * GNaL_b in INaL: 0.005157
     * Gto_b in Ito: 0.097289
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.031546
     * GKs_b in IKs: 0.002060
     * GK1_b in IK1: 0.155638
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 74.288269
     * GKb_b in IKb: 0.003781
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.024702
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1332655292
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -81.009799 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1346824732, states[0] = -86.747065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360354102, states[0] = -86.765626, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630135042667386_ORdGradInc_k_25-Pieske_1000-conf_210.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630135042667386_ORdGradInc_k_25-Pieske_1000-conf_210_1_r757633294_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630135042667386_ORdGradInc_k_25-Pieske_1000-conf_210_1_r757633294_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 118.336318
     * GNaL_b in INaL: 0.005157
     * Gto_b in Ito: 0.097289
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.031546
     * GKs_b in IKs: 0.002060
     * GK1_b in IK1: 0.155638
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 74.288269
     * GKb_b in IKb: 0.003781
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.024702
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1360354102
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.765626 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1374700584, states[0] = -86.572749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388386603, states[0] = -86.780811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401995442, states[0] = -86.807547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415586292, states[0] = -8.249791, states[40]= 0.002639
Saving checkpoint... 
Iteration: 1429265151, states[0] = -86.687720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443069920, states[0] = 2.650001, states[40]= 0.004377
Saving checkpoint... 
Iteration: 1456534873, states[0] = 17.052929, states[40]= 0.004939
Saving checkpoint... 
Iteration: 1470155789, states[0] = -81.488030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483691650, states[0] = -86.552648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497303307, states[0] = -86.729557, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.683953
 - CaMKt in component CaMK (millimolar): 0.006984
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.366806
 - nass in component intracellular_ions (millimolar): 6.366864
 - ki in component intracellular_ions (millimolar): 145.613739
 - kss in component intracellular_ions (millimolar): 145.613720
 - cansr in component intracellular_ions (millimolar): 1.306837
 - cajsr in component intracellular_ions (millimolar): 1.268775
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.008280
 - hf in component INa (dimensionless): 0.655237
 - hs in component INa (dimensionless): 0.655225
 - j in component INa (dimensionless): 0.655155
 - hsp in component INa (dimensionless): 0.406906
 - jp in component INa (dimensionless): 0.655106
 - mL in component INaL (dimensionless): 0.000236
 - hL in component INaL (dimensionless): 0.460622
 - hLp in component INaL (dimensionless): 0.236361
 - a in component Ito (dimensionless): 0.001085
 - iF in component Ito (dimensionless): 0.999451
 - iS in component Ito (dimensionless): 0.576896
 - ap in component Ito (dimensionless): 0.000553
 - iFp in component Ito (dimensionless): 0.999451
 - iSp in component Ito (dimensionless): 0.631181
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937240
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999897
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001570
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.405043
 - xs1 in component IKs (dimensionless): 0.240501
 - xs2 in component IKs (dimensionless): 0.000220
 - xk1 in component IK1 (dimensionless): 0.997059
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:36:25 (71512): called boinc_finish(0)

</stderr_txt>
]]>


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