𝕏

Task 55437688

Name HuVeMOp_20240630133542163244_ORdGradInc_k_25-BASE_MID-conf_537_0
Workunit 26325138
Created 30 Jun 2024, 11:35:56 UTC
Sent 30 Jun 2024, 13:11:47 UTC
Report deadline 3 Jul 2024, 13:11:47 UTC
Received 1 Jul 2024, 20:04:40 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214250
Run time 3 hours 6 min 7 sec
CPU time 2 hours 25 min 50 sec
Validate state Checked, but no consensus yet
Credit 0.00
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.19 MB
Peak swap size 6.28 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630133542163244_ORdGradInc_k_25-BASE_MID-conf_537.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630133542163244_ORdGradInc_k_25-BASE_MID-conf_537_0_r1992115797_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630133542163244_ORdGradInc_k_25-BASE_MID-conf_537_0_r1992115797_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 108.323605
     * GNaL_b in INaL: 0.005258
     * Gto_b in Ito: 0.070948
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033638
     * GKs_b in IKs: 0.001805
     * GK1_b in IK1: 0.162292
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 66.510629
     * GKb_b in IKb: 0.003873
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.045370
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8035575, states[0] = 32.641337, states[40]= 0.000003
Saving checkpoint... 
Iteration: 14391150, states[0] = -86.711481, states[40]= 0.000001
Saving checkpoint... 
Iteration: 21863905, states[0] = -86.700807, states[40]= 0.000001
Saving checkpoint... 
Iteration: 28927210, states[0] = -86.785408, states[40]= 0.000002
Saving checkpoint... 
Iteration: 38059744, states[0] = 24.348375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46714017, states[0] = -86.141828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53928782, states[0] = -86.833358, states[40]= 0.000002
Saving checkpoint... 
Iteration: 62582817, states[0] = 14.014993, states[40]= 0.000003
Saving checkpoint... 
Iteration: 71502965, states[0] = 21.306579, states[40]= 1.109446
Saving checkpoint... 
Iteration: 79515826, states[0] = 31.736421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87258564, states[0] = -86.499375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94522936, states[0] = 32.408942, states[40]= -0.000000
Saving checkpoint... 
Iteration: 103627795, states[0] = -14.820102, states[40]= 0.000076
Saving checkpoint... 
Iteration: 112155451, states[0] = -39.015058, states[40]= 0.000126
Saving checkpoint... 
Iteration: 121800753, states[0] = -86.678114, states[40]= 0.000001
Saving checkpoint... 
Iteration: 130794708, states[0] = -86.660824, states[40]= 0.000001
Saving checkpoint... 
Iteration: 140106090, states[0] = 1.138118, states[40]= 0.000040
Saving checkpoint... 
Iteration: 150094432, states[0] = 7.452522, states[40]= 0.000014
Saving checkpoint... 
Iteration: 158760333, states[0] = -86.525161, states[40]= 0.000001
Saving checkpoint... 
Iteration: 168586203, states[0] = 11.482175, states[40]= 0.000006
Saving checkpoint... 
Iteration: 177542354, states[0] = 28.890862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185864281, states[0] = -86.815936, states[40]= 0.000002
Saving checkpoint... 
Iteration: 193814167, states[0] = -86.719288, states[40]= 0.000001
Saving checkpoint... 
Iteration: 201053175, states[0] = 25.414307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208789709, states[0] = -86.646390, states[40]= 0.000001
Saving checkpoint... 
Iteration: 215554480, states[0] = 24.944329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223202978, states[0] = -86.062185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232161759, states[0] = -46.239852, states[40]= 0.000064
Saving checkpoint... 
Iteration: 241582452, states[0] = 13.221027, states[40]= 0.000004
Saving checkpoint... 
Iteration: 250723122, states[0] = -86.293218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260309140, states[0] = -86.703852, states[40]= 0.000001
Saving checkpoint... 
Iteration: 268595860, states[0] = 6.624025, states[40]= 0.000017
Saving checkpoint... 
Iteration: 278253207, states[0] = -86.485725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287710283, states[0] = -86.182863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297340981, states[0] = -86.774034, states[40]= 0.000002
Saving checkpoint... 
Iteration: 305555153, states[0] = 24.695256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314643005, states[0] = -28.813495, states[40]= 0.000197
Saving checkpoint... 
Iteration: 324169117, states[0] = -54.012835, states[40]= 0.000026
Saving checkpoint... 
Iteration: 333417898, states[0] = -86.867603, states[40]= 0.000002
Saving checkpoint... 
Iteration: 342091774, states[0] = 8.707192, states[40]= 0.000011
Saving checkpoint... 
Iteration: 349624640, states[0] = -13.034397, states[40]= 0.000077
Saving checkpoint... 
Iteration: 356774632, states[0] = -86.583293, states[40]= 0.000001
Saving checkpoint... 
Iteration: 363477028, states[0] = -86.900056, states[40]= 0.000002
Saving checkpoint... 
Iteration: 372275980, states[0] = -86.588089, states[40]= 0.000001
Saving checkpoint... 
Iteration: 378253193, states[0] = -86.481016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386402683, states[0] = -86.852234, states[40]= 0.000002
Saving checkpoint... 
Iteration: 393868891, states[0] = -86.813958, states[40]= 0.000002
Saving checkpoint... 
Iteration: 402616722, states[0] = -6.293995, states[40]= 0.000074
Saving checkpoint... 
Iteration: 409783551, states[0] = -86.615701, states[40]= 0.000001
Saving checkpoint... 
Iteration: 417965570, states[0] = -86.892626, states[40]= 0.000002
Saving checkpoint... 
Iteration: 426109451, states[0] = -1.120853, states[40]= 0.000052
Saving checkpoint... 
Iteration: 433774229, states[0] = -86.578026, states[40]= 0.000001
Saving checkpoint... 
Iteration: 440601421, states[0] = 3.648074, states[40]= 0.000028
Saving checkpoint... 
Iteration: 447612474, states[0] = -3.145724, states[40]= 0.000063
Saving checkpoint... 
Iteration: 455487023, states[0] = -86.899646, states[40]= 0.000002
Saving checkpoint... 
Iteration: 464330083, states[0] = -86.744716, states[40]= 0.000001
Saving checkpoint... 
Iteration: 471783125, states[0] = -86.611210, states[40]= 0.000001
Saving checkpoint... 
Iteration: 478792881, states[0] = -86.645103, states[40]= 0.000001
Saving checkpoint... 
Iteration: 487449148, states[0] = -86.881150, states[40]= 0.000002
Saving checkpoint... 
Iteration: 497315572, states[0] = -86.709742, states[40]= 0.000001
Saving checkpoint... 
Iteration: 506580943, states[0] = 13.925548, states[40]= 0.000003
Saving checkpoint... 
Iteration: 515557020, states[0] = 24.009775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524741836, states[0] = -86.408725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531868793, states[0] = -86.807458, states[40]= 0.000002
Saving checkpoint... 
Iteration: 539057719, states[0] = 23.747939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547030037, states[0] = 31.622422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554567478, states[0] = 19.866594, states[40]= 0.000001
Saving checkpoint... 
Iteration: 562536152, states[0] = 30.460990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570617614, states[0] = -6.991219, states[40]= 0.000075
Saving checkpoint... 
Iteration: 578958771, states[0] = -86.881986, states[40]= 0.000002
Saving checkpoint... 
Iteration: 586918783, states[0] = -86.856635, states[40]= 0.000002
Saving checkpoint... 
Iteration: 595987988, states[0] = -86.893547, states[40]= 0.000002
Saving checkpoint... 
Iteration: 603671725, states[0] = -56.902008, states[40]= 0.000018
Saving checkpoint... 
Iteration: 611806287, states[0] = -86.679755, states[40]= 0.000001
Saving checkpoint... 
Iteration: 620514030, states[0] = 31.006982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628481811, states[0] = -86.889770, states[40]= 0.000002
Saving checkpoint... 
Iteration: 638547200, states[0] = 27.423034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645947340, states[0] = -86.872859, states[40]= 0.000002
Saving checkpoint... 
Iteration: 654627611, states[0] = -15.676636, states[40]= 0.000078
Saving checkpoint... 
Iteration: 662623409, states[0] = -11.914642, states[40]= 0.000077
Saving checkpoint... 
Iteration: 672067190, states[0] = 19.988833, states[40]= 0.000001
Saving checkpoint... 
Iteration: 679866679, states[0] = -86.797735, states[40]= 0.000002
Saving checkpoint... 
Iteration: 687935564, states[0] = -86.863830, states[40]= 0.000002
Saving checkpoint... 
Iteration: 695893663, states[0] = -86.829209, states[40]= 0.000002
Saving checkpoint... 
Iteration: 704995437, states[0] = -86.891081, states[40]= 0.000002
Saving checkpoint... 
Iteration: 714388045, states[0] = -86.822438, states[40]= 0.000002
Saving checkpoint... 
Iteration: 723761700, states[0] = -86.508163, states[40]= 0.000001
Saving checkpoint... 
Iteration: 733037611, states[0] = 30.124622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742685309, states[0] = -75.714715, states[40]= 0.000001
Saving checkpoint... 
Iteration: 750815983, states[0] = -86.698990, states[40]= 0.000001
Saving checkpoint... 
Iteration: 759602642, states[0] = 2.977264, states[40]= 0.000031
Saving checkpoint... 
Iteration: 768160503, states[0] = -44.950490, states[40]= 0.000073
Saving checkpoint... 
Iteration: 777729325, states[0] = -86.313843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787799500, states[0] = -86.651700, states[40]= 0.000001
Saving checkpoint... 
Iteration: 795182494, states[0] = -71.231412, states[40]= 0.000003
Saving checkpoint... 
Iteration: 802566785, states[0] = 20.159519, states[40]= 0.000001
Saving checkpoint... 
Iteration: 810713238, states[0] = -86.186093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818568523, states[0] = 19.433686, states[40]= 0.000001
Saving checkpoint... 
Iteration: 828479940, states[0] = -86.879874, states[40]= 0.000002
Saving checkpoint... 
Iteration: 836857487, states[0] = -86.777059, states[40]= 0.000002
Saving checkpoint... 
Iteration: 845063646, states[0] = 21.442682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853583264, states[0] = 12.848527, states[40]= 0.000004
Saving checkpoint... 
Iteration: 862526612, states[0] = 32.053704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868979522, states[0] = -86.877856, states[40]= 0.000002
Saving checkpoint... 
Iteration: 877078983, states[0] = 14.837100, states[40]= 0.000003
Saving checkpoint... 
Iteration: 885037940, states[0] = 30.047980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890669529, states[0] = -54.400679, states[40]= 0.000025
Saving checkpoint... 
Iteration: 899642332, states[0] = -28.200195, states[40]= 0.000193
Saving checkpoint... 
Iteration: 908867089, states[0] = -86.787731, states[40]= 0.000002
Saving checkpoint... 
Iteration: 917998573, states[0] = -86.882322, states[40]= 0.000002
Saving checkpoint... 
Iteration: 925696785, states[0] = -85.514845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932005057, states[0] = 21.699064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939026375, states[0] = 32.077316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947631523, states[0] = -19.112171, states[40]= 0.000092
Saving checkpoint... 
Iteration: 956444953, states[0] = -86.857230, states[40]= 0.000002
Saving checkpoint... 
Iteration: 964544976, states[0] = 28.119382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972583715, states[0] = 12.638630, states[40]= 0.000005
Saving checkpoint... 
Iteration: 981593230, states[0] = 7.990648, states[40]= 0.000013
Saving checkpoint... 
Iteration: 989871763, states[0] = -86.790273, states[40]= 0.000002
Saving checkpoint... 
Iteration: 997798389, states[0] = -86.638506, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1005754070, states[0] = -86.456103, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1012510596, states[0] = 29.250410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019762657, states[0] = -86.498850, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1027906247, states[0] = -86.825945, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1035294688, states[0] = -86.625054, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1044028771, states[0] = 31.810907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052206082, states[0] = -86.091662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061190455, states[0] = -82.438537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069638956, states[0] = -25.364485, states[40]= 0.000166
Saving checkpoint... 
Iteration: 1076817958, states[0] = -86.688730, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1084001143, states[0] = 36.447285, states[40]= 1.786496
Saving checkpoint... 
Iteration: 1093204869, states[0] = -86.066932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102609235, states[0] = -0.951200, states[40]= 0.000051
Saving checkpoint... 
Iteration: 1110120723, states[0] = -9.536823, states[40]= 0.000077
Saving checkpoint... 
Iteration: 1117831936, states[0] = -86.718318, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1125705126, states[0] = -86.070552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133902568, states[0] = -86.817722, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1142032452, states[0] = 31.230007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149668259, states[0] = -52.982547, states[40]= 0.000029
Saving checkpoint... 
Iteration: 1158410254, states[0] = -86.823419, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1166210916, states[0] = -86.146953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173203654, states[0] = -86.033967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181267474, states[0] = -86.513697, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1188443472, states[0] = -86.845712, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1196254347, states[0] = -86.448611, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1203398937, states[0] = -86.811089, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1212436729, states[0] = -86.840480, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1220236774, states[0] = -86.343628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227578882, states[0] = 14.890914, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1236022839, states[0] = 32.277058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244296470, states[0] = -86.621014, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1250930770, states[0] = -86.834803, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1256733849, states[0] = -86.322438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263721616, states[0] = -86.233512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273076711, states[0] = 15.876413, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1282122226, states[0] = -10.826330, states[40]= 0.000077
Saving checkpoint... 
Iteration: 1290411986, states[0] = -86.818816, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1297558770, states[0] = 23.363602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302597471, states[0] = 5.808922, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1310134142, states[0] = -21.330373, states[40]= 0.000112
Saving checkpoint... 
Iteration: 1317115761, states[0] = -5.495107, states[40]= 0.000071
Saving checkpoint... 
Iteration: 1324373934, states[0] = -86.777665, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1332698950, states[0] = -85.775332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338101444, states[0] = 3.666327, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1347193117, states[0] = -84.294885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355123733, states[0] = -12.150950, states[40]= 0.000077
Saving checkpoint... 
Iteration: 1364386006, states[0] = -86.790249, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1372035972, states[0] = 30.516851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379038358, states[0] = 29.954743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385878681, states[0] = -86.780733, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1394777124, states[0] = -86.544827, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1401557860, states[0] = 23.710983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409859780, states[0] = -86.754099, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1418006173, states[0] = 24.216540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426630010, states[0] = -17.751158, states[40]= 0.000083
Saving checkpoint... 
Iteration: 1433368996, states[0] = -86.766149, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1439726249, states[0] = -86.260100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446275696, states[0] = -86.536640, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1455154427, states[0] = -38.963341, states[40]= 0.000127
Saving checkpoint... 
Iteration: 1464157798, states[0] = -42.203530, states[40]= 0.000096
Saving checkpoint... 
Iteration: 1471685704, states[0] = -76.164363, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1477394671, states[0] = -86.794267, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1486618692, states[0] = -7.806765, states[40]= 0.000076
Saving checkpoint... 
Iteration: 1494431458, states[0] = -86.824089, states[40]= 0.000002
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.731984
 - CaMKt in component CaMK (millimolar): 0.024050
 - cass in component intracellular_ions (millimolar): 0.000090
 - nai in component intracellular_ions (millimolar): 8.174510
 - nass in component intracellular_ions (millimolar): 8.174654
 - ki in component intracellular_ions (millimolar): 143.314934
 - kss in component intracellular_ions (millimolar): 143.314898
 - cansr in component intracellular_ions (millimolar): 1.963160
 - cajsr in component intracellular_ions (millimolar): 1.891967
 - cai in component intracellular_ions (millimolar): 0.000093
 - m in component INa (dimensionless): 0.008241
 - hf in component INa (dimensionless): 0.657018
 - hs in component INa (dimensionless): 0.656988
 - j in component INa (dimensionless): 0.656816
 - hsp in component INa (dimensionless): 0.408751
 - jp in component INa (dimensionless): 0.656693
 - mL in component INaL (dimensionless): 0.000234
 - hL in component INaL (dimensionless): 0.454558
 - hLp in component INaL (dimensionless): 0.222307
 - a in component Ito (dimensionless): 0.001081
 - iF in component Ito (dimensionless): 0.999455
 - iS in component Ito (dimensionless): 0.538267
 - ap in component Ito (dimensionless): 0.000551
 - iFp in component Ito (dimensionless): 0.999455
 - iSp in component Ito (dimensionless): 0.582025
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.880521
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999643
 - jca in component ICaL (dimensionless): 0.999945
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003467
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.506174
 - xs1 in component IKs (dimensionless): 0.327607
 - xs2 in component IKs (dimensionless): 0.000219
 - xk1 in component IK1 (dimensionless): 0.997048
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
22:04:27 (13508): called boinc_finish(0)

</stderr_txt>
]]>


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