𝕏

Task 55437332

Name HuVeMOp_20240630133542163244_ORdGradInc_k_25-Pueyo_APDR-conf_802_0
Workunit 26324960
Created 30 Jun 2024, 11:35:46 UTC
Sent 30 Jun 2024, 13:15:58 UTC
Report deadline 3 Jul 2024, 22:51:58 UTC
Received 30 Jun 2024, 20:55:00 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213791
Run time 2 hours 43 min 41 sec
CPU time 2 hours 43 min 41 sec
Validate state Valid
Credit 61.13
Device peak FLOPS 3.69 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.64 MB
Peak swap size 6.22 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630133542163244_ORdGradInc_k_25-Pueyo_APDR-conf_802.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630133542163244_ORdGradInc_k_25-Pueyo_APDR-conf_802_0_r703454758_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630133542163244_ORdGradInc_k_25-Pueyo_APDR-conf_802_0_r703454758_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 112.177087
     * GNaL_b in INaL: 0.006003
     * Gto_b in Ito: 0.099228
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.030424
     * GKs_b in IKs: 0.001891
     * GK1_b in IK1: 0.175834
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 65.988121
     * GKb_b in IKb: 0.003729
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029747
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12694530, states[0] = -94.813828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23288988, states[0] = -94.927961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35456800, states[0] = -94.990696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48613525, states[0] = -28.317319, states[40]= 0.000602
Saving checkpoint... 
Iteration: 61931828, states[0] = -94.976908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74634095, states[0] = -47.184423, states[40]= 0.000049
Saving checkpoint... 
Iteration: 85973175, states[0] = -94.981035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97143851, states[0] = -57.256568, states[40]= 0.000009
Saving checkpoint... 
Iteration: 110072692, states[0] = 3.017903, states[40]= 0.004477
Saving checkpoint... 
Iteration: 122166746, states[0] = -90.255280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135427545, states[0] = -94.969826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148668778, states[0] = -92.142449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161902378, states[0] = -94.962812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175143941, states[0] = -57.162317, states[40]= 0.000010
Saving checkpoint... 
Iteration: 188351926, states[0] = -94.943665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201630633, states[0] = -43.388784, states[40]= 0.000088
Saving checkpoint... 
Iteration: 214929635, states[0] = -94.969538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228140927, states[0] = -53.896493, states[40]= 0.000017
Saving checkpoint... 
Iteration: 241354492, states[0] = -94.944689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254578328, states[0] = 0.204295, states[40]= 0.004198
Saving checkpoint... 
Iteration: 267798176, states[0] = -94.910017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280929523, states[0] = -94.969395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294240592, states[0] = -94.847037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307472211, states[0] = -94.977377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320047754, states[0] = 13.001914, states[40]= 0.004757
Saving checkpoint... 
Iteration: 329923995, states[0] = -94.968057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342962534, states[0] = -94.975799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356107011, states[0] = -21.902464, states[40]= 0.000896
Saving checkpoint... 
Iteration: 369300591, states[0] = -94.911836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382408536, states[0] = -94.964031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395552488, states[0] = 11.324112, states[40]= 0.004736
Saving checkpoint... 
Iteration: 408831334, states[0] = -94.932551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422065561, states[0] = 6.252434, states[40]= 0.004654
Saving checkpoint... 
Iteration: 435323362, states[0] = -94.927741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448608418, states[0] = -23.147702, states[40]= 0.000842
Saving checkpoint... 
Iteration: 461808645, states[0] = -94.917825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474981988, states[0] = -94.978664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487684947, states[0] = -94.731861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500913372, states[0] = -94.965244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514207425, states[0] = -94.790667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527481421, states[0] = -94.978543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540689691, states[0] = -94.752018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553915982, states[0] = -94.965883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567216666, states[0] = -94.807947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580433070, states[0] = -94.969939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593681491, states[0] = -94.696278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606994339, states[0] = -94.980181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619989914, states[0] = -94.979611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629653584, states[0] = -68.760681, states[40]= 0.000001
Saving checkpoint... 
Iteration: 642480062, states[0] = -94.978260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655646900, states[0] = -60.446354, states[40]= 0.000005
Saving checkpoint... 
Iteration: 668799437, states[0] = -94.910686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682002236, states[0] = 41.897890, states[40]= 0.117379
Saving checkpoint... 
Iteration: 695168740, states[0] = -92.076538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708472593, states[0] = -94.977111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721721078, states[0] = -94.815645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735012715, states[0] = 21.307900, states[40]= 0.027805
Saving checkpoint... 
Iteration: 748232840, states[0] = -94.835023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761519886, states[0] = 20.592022, states[40]= 0.008779
Saving checkpoint... 
Iteration: 774774372, states[0] = -94.887966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787924313, states[0] = -94.967765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801100009, states[0] = -15.686842, states[40]= 0.001368
Saving checkpoint... 
Iteration: 814339057, states[0] = -94.936521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826398598, states[0] = -94.960796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838956814, states[0] = -94.974420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851287545, states[0] = -94.900519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863712832, states[0] = -94.800672, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630133542163244_ORdGradInc_k_25-Pueyo_APDR-conf_802.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630133542163244_ORdGradInc_k_25-Pueyo_APDR-conf_802_0_r703454758_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630133542163244_ORdGradInc_k_25-Pueyo_APDR-conf_802_0_r703454758_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 112.177087
     * GNaL_b in INaL: 0.006003
     * Gto_b in Ito: 0.099228
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.030424
     * GKs_b in IKs: 0.001891
     * GK1_b in IK1: 0.175834
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 65.988121
     * GKb_b in IKb: 0.003729
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029747
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 863712832
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.800672 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 876726969, states[0] = -94.825502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889964221, states[0] = -94.975641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903152595, states[0] = -67.419879, states[40]= 0.000002
Saving checkpoint... 
Iteration: 915157521, states[0] = -74.670136, states[40]= 0.000001
Saving checkpoint... 
Iteration: 925965049, states[0] = -94.975748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938964174, states[0] = -94.975595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952129931, states[0] = -42.696845, states[40]= 0.000097
Saving checkpoint... 
Iteration: 965207327, states[0] = -94.790114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978360483, states[0] = -94.946751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990642462, states[0] = -55.533733, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1002528950, states[0] = 18.803381, states[40]= 0.005629
Saving checkpoint... 
Iteration: 1015651018, states[0] = -65.376410, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1028775428, states[0] = -94.888838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042482546, states[0] = -94.978289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056138249, states[0] = -51.074231, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1070085681, states[0] = -4.219367, states[40]= 0.003494
Saving checkpoint... 
Iteration: 1084110638, states[0] = -25.111108, states[40]= 0.000758
Saving checkpoint... 
Iteration: 1098023755, states[0] = 19.948484, states[40]= 0.006710
Saving checkpoint... 
Iteration: 1112103988, states[0] = -19.219982, states[40]= 0.001043
Saving checkpoint... 
Iteration: 1126121867, states[0] = -35.147699, states[40]= 0.000284
Saving checkpoint... 
Iteration: 1140023162, states[0] = 20.059656, states[40]= 0.006918
Saving checkpoint... 
Iteration: 1153885743, states[0] = -94.956387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167829115, states[0] = -94.930649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181753549, states[0] = -94.863873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195815809, states[0] = -94.922236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209906533, states[0] = -94.962811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221679299, states[0] = -94.646410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233605677, states[0] = -20.719485, states[40]= 0.000954
Saving checkpoint... 
Iteration: 1247507038, states[0] = 23.040892, states[40]= 0.111731
Saving checkpoint... 
Iteration: 1261479802, states[0] = -94.977730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275362711, states[0] = -94.947474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289187252, states[0] = -94.742985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303363989, states[0] = -94.947993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317126177, states[0] = -39.121175, states[40]= 0.000164
Saving checkpoint... 
Iteration: 1331022478, states[0] = 20.182456, states[40]= 0.007196
Saving checkpoint... 
Iteration: 1344949551, states[0] = -94.972691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358668043, states[0] = -91.490189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372492289, states[0] = -94.979315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386536873, states[0] = 16.591367, states[40]= 0.005004
Saving checkpoint... 
Iteration: 1400428734, states[0] = -94.968311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414211572, states[0] = -94.797870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428251515, states[0] = -94.861070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442104688, states[0] = -19.841592, states[40]= 0.001003
Saving checkpoint... 
Iteration: 1455985616, states[0] = -94.978379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469637625, states[0] = -50.425458, states[40]= 0.000029
Saving checkpoint... 
Iteration: 1482501255, states[0] = 49.498097, states[40]= 0.049632
Saving checkpoint... 
Iteration: 1495916184, states[0] = -94.965184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1509928405, states[0] = 18.300058, states[40]= 0.006918
Saving checkpoint... 
Iteration: 1523934294, states[0] = -95.144395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537708503, states[0] = -95.115542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1550539690, states[0] = -85.636390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564393101, states[0] = -95.097943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1578183076, states[0] = -95.079327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1591931902, states[0] = -72.473529, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1604408377, states[0] = 23.269746, states[40]= 0.078922
Saving checkpoint... 
Iteration: 1617119623, states[0] = -55.762632, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1629951275, states[0] = 7.575217, states[40]= 0.005434
Saving checkpoint... 
Iteration: 1642321549, states[0] = -58.198845, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1656168229, states[0] = -95.047458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1670007281, states[0] = -95.133528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1683690630, states[0] = -24.205680, states[40]= 0.000791
Saving checkpoint... 
Iteration: 1697485383, states[0] = -18.769097, states[40]= 0.001174
Saving checkpoint... 
Iteration: 1711107480, states[0] = -95.134049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1725016657, states[0] = 21.104937, states[40]= 0.014588
Saving checkpoint... 
Iteration: 1738961702, states[0] = -95.025117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1752884116, states[0] = -95.224685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1766910761, states[0] = -95.139729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1780795727, states[0] = -95.232875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1794614346, states[0] = 21.560450, states[40]= 0.021277
Saving checkpoint... 
Iteration: 1807356818, states[0] = -94.989146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1819578134, states[0] = -0.921831, states[40]= 0.004102
Saving checkpoint... 
Iteration: 1833122765, states[0] = -37.613953, states[40]= 0.000204
Saving checkpoint... 
Iteration: 1844631300, states[0] = -45.327764, states[40]= 0.000065
Saving checkpoint... 
Iteration: 1857803539, states[0] = -94.924440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1871720376, states[0] = -94.821246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1885708112, states[0] = -94.795982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1899611125, states[0] = -25.754307, states[40]= 0.000728
Saving checkpoint... 
Iteration: 1913499087, states[0] = -94.981854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1927284680, states[0] = -94.898481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1941072902, states[0] = 2.936763, states[40]= 0.004470
Saving checkpoint... 
Iteration: 1955000268, states[0] = -62.025278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1968837005, states[0] = -94.934852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1982650381, states[0] = -64.608256, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1996535856, states[0] = 16.896932, states[40]= 0.005053
Saving checkpoint... 
Iteration: 2010597760, states[0] = -13.715697, states[40]= 0.001636
Saving checkpoint... 
Iteration: 2024176625, states[0] = -94.516219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2038116301, states[0] = -30.142416, states[40]= 0.000510
Saving checkpoint... 
Iteration: 2051903085, states[0] = -94.961113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2065739321, states[0] = -94.843709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2079611962, states[0] = -26.283596, states[40]= 0.000704
Saving checkpoint... 
Iteration: 2093847960, states[0] = -94.940001, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.855481
 - CaMKt in component CaMK (millimolar): 0.007549
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.786504
 - nass in component intracellular_ions (millimolar): 6.786565
 - ki in component intracellular_ions (millimolar): 145.182980
 - kss in component intracellular_ions (millimolar): 145.182961
 - cansr in component intracellular_ions (millimolar): 1.342015
 - cajsr in component intracellular_ions (millimolar): 1.302908
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003635
 - hf in component INa (dimensionless): 0.879194
 - hs in component INa (dimensionless): 0.879189
 - j in component INa (dimensionless): 0.879160
 - hsp in component INa (dimensionless): 0.724311
 - jp in component INa (dimensionless): 0.879140
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.707273
 - hLp in component INaL (dimensionless): 0.446513
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.614748
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.688726
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933362
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999875
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001706
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332581
 - xs1 in component IKs (dimensionless): 0.249299
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997349
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:12:31 (14024): called boinc_finish(0)

</stderr_txt>
]]>


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