𝕏

Task 55437162

Name HuVeMOp_20240630132603625418_ORdGradInc_k_25-Pueyo_APDR-conf_70_1
Workunit 26324883
Created 30 Jun 2024, 11:26:23 UTC
Sent 30 Jun 2024, 13:08:08 UTC
Report deadline 3 Jul 2024, 22:44:08 UTC
Received 1 Jul 2024, 13:28:32 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213754
Run time 3 hours 12 min 57 sec
CPU time 3 hours 8 min 2 sec
Validate state Valid
Credit 60.40
Device peak FLOPS 3.69 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.59 MB
Peak swap size 6.22 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630132603625418_ORdGradInc_k_25-Pueyo_APDR-conf_70.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630132603625418_ORdGradInc_k_25-Pueyo_APDR-conf_70_1_r294401134_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630132603625418_ORdGradInc_k_25-Pueyo_APDR-conf_70_1_r294401134_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 91.635627
     * GNaL_b in INaL: 0.004458
     * Gto_b in Ito: 0.083149
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.030835
     * GKs_b in IKs: 0.001999
     * GK1_b in IK1: 0.178649
     * Gncx_b in INaCa_i: 0.000953
     * Pnak_b in INaK: 70.045128
     * GKb_b in IKb: 0.003709
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.042215
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11445320, states[0] = -95.111744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23413883, states[0] = -95.078149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34711006, states[0] = -94.917320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46679154, states[0] = -94.843278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57515257, states[0] = 21.755834, states[40]= 0.016784
Saving checkpoint... 
Iteration: 69373047, states[0] = -95.029809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81337780, states[0] = -95.012234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92867742, states[0] = -95.022254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104845722, states[0] = -95.011850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115491166, states[0] = -95.045520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127423634, states[0] = -95.034086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139555484, states[0] = 8.977293, states[40]= 0.004855
Saving checkpoint... 
Iteration: 151481512, states[0] = -95.042471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163672814, states[0] = -94.766761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174967976, states[0] = -95.040179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186958578, states[0] = -95.038649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197998016, states[0] = -95.043566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209953410, states[0] = -95.037651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221979266, states[0] = -95.041262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233942187, states[0] = -95.035651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245861968, states[0] = -95.014442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257807245, states[0] = -94.987291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269863284, states[0] = -95.014885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281828593, states[0] = -94.999581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293960511, states[0] = -95.038525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305866243, states[0] = -95.015922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317840241, states[0] = -95.005255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330007803, states[0] = 23.946527, states[40]= 0.086112
Saving checkpoint... 
Iteration: 342087831, states[0] = -9.456002, states[40]= 0.002443
Saving checkpoint... 
Iteration: 353373161, states[0] = -95.018298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365128626, states[0] = -48.799032, states[40]= 0.000033
Saving checkpoint... 
Iteration: 377005406, states[0] = 26.900927, states[40]= 0.141612
Saving checkpoint... 
Iteration: 389062525, states[0] = 5.984533, states[40]= 0.004744
Saving checkpoint... 
Iteration: 401131442, states[0] = -51.783019, states[40]= 0.000020
Saving checkpoint... 
Iteration: 412756413, states[0] = -94.944507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422818047, states[0] = -94.993697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434740381, states[0] = -94.925726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446786355, states[0] = -94.972217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458777822, states[0] = -94.965154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470673368, states[0] = -94.773803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482838517, states[0] = -95.004329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494756839, states[0] = -94.944907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506967442, states[0] = -95.039368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519047198, states[0] = 12.317111, states[40]= 0.004964
Saving checkpoint... 
Iteration: 531277875, states[0] = -94.965149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543093918, states[0] = -14.980568, states[40]= 0.001466
Saving checkpoint... 
Iteration: 555131953, states[0] = -52.330273, states[40]= 0.000019
Saving checkpoint... 
Iteration: 567338721, states[0] = -95.004367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575102619, states[0] = -23.268115, states[40]= 0.000778
Saving checkpoint... 
Iteration: 586468093, states[0] = -95.039405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598682601, states[0] = -94.827906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610835751, states[0] = -95.002921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622460069, states[0] = -95.038219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634340132, states[0] = -95.004980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646231066, states[0] = -94.913180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657393848, states[0] = -95.024441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669563015, states[0] = 5.764017, states[40]= 0.004733
Saving checkpoint... 
Iteration: 681654056, states[0] = -82.693389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693716878, states[0] = -94.891930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705804394, states[0] = -94.985085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717835395, states[0] = -95.002675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729950611, states[0] = -95.036659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741933900, states[0] = -95.033684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752986477, states[0] = -95.041645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764624020, states[0] = -44.035283, states[40]= 0.000070
Saving checkpoint... 
Iteration: 776503425, states[0] = 33.571476, states[40]= 0.157634
Saving checkpoint... 
Iteration: 788585029, states[0] = -7.133363, states[40]= 0.002937
Saving checkpoint... 
Iteration: 800128052, states[0] = -48.196807, states[40]= 0.000036
Saving checkpoint... 
Iteration: 812128604, states[0] = -48.775375, states[40]= 0.000033
Saving checkpoint... 
Iteration: 824235104, states[0] = -94.918576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836376139, states[0] = -95.018958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848429059, states[0] = -95.032663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860209198, states[0] = -94.879111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871899364, states[0] = -95.025791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880078511, states[0] = -2.448736, states[40]= 0.003866
Saving checkpoint... 
Iteration: 892118089, states[0] = -38.121465, states[40]= 0.000167
Saving checkpoint... 
Iteration: 904150227, states[0] = -75.692400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916299897, states[0] = -94.981907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928442530, states[0] = -95.035146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940620356, states[0] = -40.354855, states[40]= 0.000121
Saving checkpoint... 
Iteration: 952703567, states[0] = -94.869193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964698071, states[0] = -94.859148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976861491, states[0] = -95.013698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988948279, states[0] = -95.036095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001053276, states[0] = 9.911843, states[40]= 0.004881
Saving checkpoint... 
Iteration: 1013102461, states[0] = -23.117191, states[40]= 0.000785
Saving checkpoint... 
Iteration: 1025257675, states[0] = -94.945435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037327317, states[0] = -94.998375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049432493, states[0] = -95.033203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061236641, states[0] = -94.920456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073324508, states[0] = -94.996854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085249066, states[0] = -94.935828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097399125, states[0] = -95.025573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109427939, states[0] = -95.032258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121489026, states[0] = -95.041689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133516638, states[0] = 21.670010, states[40]= 0.013619
Saving checkpoint... 
Iteration: 1145186742, states[0] = -94.836911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157207117, states[0] = -94.875316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169292107, states[0] = -94.976142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181240861, states[0] = -94.925820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193324074, states[0] = -94.996537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205354818, states[0] = -95.010939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217430169, states[0] = -95.032632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229363901, states[0] = -95.014425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241432243, states[0] = -95.033023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253463072, states[0] = -95.038232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265567071, states[0] = 3.871443, states[40]= 0.004619
Saving checkpoint... 
Iteration: 1277501648, states[0] = 45.337498, states[40]= 0.079458
Saving checkpoint... 
Iteration: 1289422023, states[0] = -95.030903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301565984, states[0] = 4.391365, states[40]= 0.004655
Saving checkpoint... 
Iteration: 1313692191, states[0] = -94.847725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325838353, states[0] = -95.003675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337883878, states[0] = -95.021068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349697305, states[0] = -94.857452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361864166, states[0] = -95.014432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374051966, states[0] = 10.439745, states[40]= 0.004896
Saving checkpoint... 
Iteration: 1386023207, states[0] = 20.315840, states[40]= 0.007452
Saving checkpoint... 
Iteration: 1398109882, states[0] = -30.199039, states[40]= 0.000451
Saving checkpoint... 
Iteration: 1410251565, states[0] = -94.938469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422414684, states[0] = -95.029187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434344318, states[0] = -95.006335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445912212, states[0] = -95.028598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457990105, states[0] = -95.041582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470191500, states[0] = -94.846270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482388572, states[0] = -95.022372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494609849, states[0] = -30.167391, states[40]= 0.000453
Saving checkpoint... 
Iteration: 1506709905, states[0] = -47.034282, states[40]= 0.000043
Saving checkpoint... 
Iteration: 1518757689, states[0] = -95.062948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1531041092, states[0] = -93.456942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1543061305, states[0] = -95.092113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1554900837, states[0] = 43.125729, states[40]= 0.013775
Saving checkpoint... 
Iteration: 1567057746, states[0] = -95.089414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579371466, states[0] = -95.128197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1591239637, states[0] = 12.640329, states[40]= 0.006002
Saving checkpoint... 
Iteration: 1603278451, states[0] = -15.131466, states[40]= 0.001631
Saving checkpoint... 
Iteration: 1615401426, states[0] = -95.190651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1627602979, states[0] = -42.397084, states[40]= 0.000093
Saving checkpoint... 
Iteration: 1639758293, states[0] = -95.261724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1651776790, states[0] = -95.276751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1663798230, states[0] = -95.290747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1675746648, states[0] = -95.251184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1687026109, states[0] = -72.535637, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1699040334, states[0] = -93.864237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1711135703, states[0] = -95.239593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1723091832, states[0] = -95.175168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1734349095, states[0] = 7.710616, states[40]= 0.005560
Saving checkpoint... 
Iteration: 1746487704, states[0] = -95.167340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1758664465, states[0] = -1.936101, states[40]= 0.004456
Saving checkpoint... 
Iteration: 1770566076, states[0] = -95.268895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1782617861, states[0] = 21.351548, states[40]= 0.012981
Saving checkpoint... 
Iteration: 1794706141, states[0] = -46.121069, states[40]= 0.000053
Saving checkpoint... 
Iteration: 1806440131, states[0] = -95.076307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1818582546, states[0] = -6.892485, states[40]= 0.003030
Saving checkpoint... 
Iteration: 1830546535, states[0] = 12.140760, states[40]= 0.004980
Saving checkpoint... 
Iteration: 1842534571, states[0] = 16.707691, states[40]= 0.005455
Saving checkpoint... 
Iteration: 1854673048, states[0] = -94.791429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1866595314, states[0] = -16.825360, states[40]= 0.001241
Saving checkpoint... 
Iteration: 1878556407, states[0] = 8.500114, states[40]= 0.004843
Saving checkpoint... 
Iteration: 1890575701, states[0] = -0.857755, states[40]= 0.004121
Saving checkpoint... 
Iteration: 1902666499, states[0] = -94.439300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914794018, states[0] = -94.978967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1926806680, states[0] = -94.987070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1938955955, states[0] = -95.037594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1951024941, states[0] = 19.870721, states[40]= 0.006875
Saving checkpoint... 
Iteration: 1962989053, states[0] = -95.041533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1975076052, states[0] = -0.934647, states[40]= 0.004106
Saving checkpoint... 
Iteration: 1987124206, states[0] = -44.242437, states[40]= 0.000067
Saving checkpoint... 
Iteration: 1999047665, states[0] = 12.133186, states[40]= 0.004956
Saving checkpoint... 
Iteration: 2011118164, states[0] = -38.202775, states[40]= 0.000165
Saving checkpoint... 
Iteration: 2022796202, states[0] = -94.978572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2034900945, states[0] = -95.025405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2046792451, states[0] = -94.975775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2058959152, states[0] = -95.037064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2070954076, states[0] = -95.036259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2082880890, states[0] = -95.019583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2094623061, states[0] = -43.062480, states[40]= 0.000081
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.918034
 - CaMKt in component CaMK (millimolar): 0.007029
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.587750
 - nass in component intracellular_ions (millimolar): 6.587807
 - ki in component intracellular_ions (millimolar): 145.388702
 - kss in component intracellular_ions (millimolar): 145.388684
 - cansr in component intracellular_ions (millimolar): 1.314697
 - cajsr in component intracellular_ions (millimolar): 1.276815
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003613
 - hf in component INa (dimensionless): 0.880281
 - hs in component INa (dimensionless): 0.880277
 - j in component INa (dimensionless): 0.880252
 - hsp in component INa (dimensionless): 0.726362
 - jp in component INa (dimensionless): 0.880234
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710865
 - hLp in component INaL (dimensionless): 0.454067
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.623090
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.698551
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936833
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999891
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001607
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.320570
 - xs1 in component IKs (dimensionless): 0.238262
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997333
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
06:13:21 (2228): called boinc_finish(0)

</stderr_txt>
]]>


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