𝕏

Task 55436965

Name HuVeMOp_20240630132603625418_ORdGradInc_k_25-Pueyo_APDR-conf_733_0
Workunit 26324785
Created 30 Jun 2024, 11:26:18 UTC
Sent 30 Jun 2024, 13:15:58 UTC
Report deadline 3 Jul 2024, 22:51:58 UTC
Received 30 Jun 2024, 19:23:43 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213791
Run time 2 hours 48 min 3 sec
CPU time 2 hours 48 min 3 sec
Validate state Valid
Credit 66.17
Device peak FLOPS 3.69 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.64 MB
Peak swap size 6.21 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630132603625418_ORdGradInc_k_25-Pueyo_APDR-conf_733.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630132603625418_ORdGradInc_k_25-Pueyo_APDR-conf_733_0_r1663025075_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630132603625418_ORdGradInc_k_25-Pueyo_APDR-conf_733_0_r1663025075_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 98.493880
     * GNaL_b in INaL: 0.004585
     * Gto_b in Ito: 0.091264
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033293
     * GKs_b in IKs: 0.001861
     * GK1_b in IK1: 0.155420
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 68.112263
     * GKb_b in IKb: 0.003689
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.040900
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11753465, states[0] = -95.036467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24940732, states[0] = -95.103667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38095202, states[0] = -20.247228, states[40]= 0.000923
Saving checkpoint... 
Iteration: 51003007, states[0] = 35.292791, states[40]= 0.144968
Saving checkpoint... 
Iteration: 64237959, states[0] = -94.937550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77526260, states[0] = 18.652101, states[40]= 0.006462
Saving checkpoint... 
Iteration: 90840717, states[0] = -95.022312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104093292, states[0] = -16.745416, states[40]= 0.001236
Saving checkpoint... 
Iteration: 117445251, states[0] = -95.052925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130738471, states[0] = -94.923817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143965171, states[0] = -95.054588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157259820, states[0] = -94.950690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170408293, states[0] = -95.041504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183591275, states[0] = -14.521719, states[40]= 0.001522
Saving checkpoint... 
Iteration: 196722704, states[0] = -94.896538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208002661, states[0] = 37.874480, states[40]= 0.127788
Saving checkpoint... 
Iteration: 219276863, states[0] = -94.968156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231367690, states[0] = -95.027181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244476245, states[0] = -95.054679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257610850, states[0] = -33.987620, states[40]= 0.000274
Saving checkpoint... 
Iteration: 270870485, states[0] = -95.028180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284066202, states[0] = 3.512466, states[40]= 0.004541
Saving checkpoint... 
Iteration: 296387695, states[0] = -95.034397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308617834, states[0] = -41.109164, states[40]= 0.000102
Saving checkpoint... 
Iteration: 321873328, states[0] = -95.029217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335062369, states[0] = 5.331890, states[40]= 0.004651
Saving checkpoint... 
Iteration: 348380632, states[0] = -95.031901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361675817, states[0] = -94.780226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374824722, states[0] = -95.005437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388131837, states[0] = -56.200262, states[40]= 0.000009
Saving checkpoint... 
Iteration: 401401532, states[0] = -95.038653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413529171, states[0] = 17.956586, states[40]= 0.005951
Saving checkpoint... 
Iteration: 425354520, states[0] = -95.021241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437075827, states[0] = -1.827346, states[40]= 0.003936
Saving checkpoint... 
Iteration: 448208320, states[0] = -94.869486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459744212, states[0] = -94.929340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472048718, states[0] = 11.072148, states[40]= 0.004851
Saving checkpoint... 
Iteration: 485104314, states[0] = -27.437847, states[40]= 0.000548
Saving checkpoint... 
Iteration: 498686896, states[0] = -94.823320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509010413, states[0] = 21.742550, states[40]= 0.047222
Saving checkpoint... 
Iteration: 521474992, states[0] = -95.054218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534550101, states[0] = 10.527181, states[40]= 0.004831
Saving checkpoint... 
Iteration: 547607145, states[0] = -30.266358, states[40]= 0.000421
Saving checkpoint... 
Iteration: 560573036, states[0] = -0.130206, states[40]= 0.004179
Saving checkpoint... 
Iteration: 573834549, states[0] = -95.011039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587028292, states[0] = 18.209391, states[40]= 0.006088
Saving checkpoint... 
Iteration: 600338289, states[0] = -95.013065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613516726, states[0] = 20.748510, states[40]= 0.013571
Saving checkpoint... 
Iteration: 626760109, states[0] = -94.949573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640080873, states[0] = -5.329242, states[40]= 0.003297
Saving checkpoint... 
Iteration: 652891840, states[0] = -95.035500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663955696, states[0] = -95.050988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677087855, states[0] = -11.239369, states[40]= 0.002077
Saving checkpoint... 
Iteration: 690328461, states[0] = -95.007472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703523557, states[0] = 19.436761, states[40]= 0.007268
Saving checkpoint... 
Iteration: 716711282, states[0] = -94.875048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729904249, states[0] = -95.039222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743223411, states[0] = -94.897011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756557528, states[0] = 7.474214, states[40]= 0.004739
Saving checkpoint... 
Iteration: 769852103, states[0] = -95.019888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783029503, states[0] = 17.859367, states[40]= 0.005904
Saving checkpoint... 
Iteration: 796432303, states[0] = -95.046257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808275738, states[0] = -94.966447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821364603, states[0] = -95.025385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834571858, states[0] = 0.544441, states[40]= 0.004262
Saving checkpoint... 
Iteration: 847851794, states[0] = -95.019691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860986971, states[0] = -95.055668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874248988, states[0] = -94.935529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887392426, states[0] = -95.035531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900636335, states[0] = -61.292764, states[40]= 0.000004
Saving checkpoint... 
Iteration: 913842119, states[0] = -95.014872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927068805, states[0] = 2.196499, states[40]= 0.004434
Saving checkpoint... 
Iteration: 940384074, states[0] = -95.032712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953397362, states[0] = -95.037032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966612491, states[0] = -35.639325, states[40]= 0.000221
Saving checkpoint... 
Iteration: 979910967, states[0] = -95.040922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993104196, states[0] = -27.319773, states[40]= 0.000554
Saving checkpoint... 
Iteration: 1006371259, states[0] = -95.027948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019537884, states[0] = 15.124088, states[40]= 0.005173
Saving checkpoint... 
Iteration: 1032783789, states[0] = -94.974042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046030585, states[0] = 17.535581, states[40]= 0.005764
Saving checkpoint... 
Iteration: 1059292259, states[0] = -94.981514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072585656, states[0] = -9.251498, states[40]= 0.002474
Saving checkpoint... 
Iteration: 1085496733, states[0] = -95.056751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097883855, states[0] = -95.032531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110264951, states[0] = -94.954810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123510846, states[0] = 21.644518, states[40]= 0.042641
Saving checkpoint... 
Iteration: 1136653864, states[0] = -86.491733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149384903, states[0] = -95.032858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161906387, states[0] = -95.039540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174008616, states[0] = 22.351526, states[40]= 0.072641
Saving checkpoint... 
Iteration: 1185846796, states[0] = -95.017053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197801553, states[0] = -94.988933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211010153, states[0] = 21.808212, states[40]= 0.050233
Saving checkpoint... 
Iteration: 1224324428, states[0] = -95.004685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237634230, states[0] = -58.881844, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1250859383, states[0] = -95.022868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263999172, states[0] = -95.056922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277260361, states[0] = -94.949433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290603344, states[0] = -26.469808, states[40]= 0.000593
Saving checkpoint... 
Iteration: 1303782790, states[0] = -94.972933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317050089, states[0] = 10.532124, states[40]= 0.004832
Saving checkpoint... 
Iteration: 1330304846, states[0] = -94.991341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343424597, states[0] = -95.044127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356606339, states[0] = -29.459696, states[40]= 0.000456
Saving checkpoint... 
Iteration: 1369925570, states[0] = -95.044339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383202425, states[0] = -94.856993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395086292, states[0] = -9.815699, states[40]= 0.002358
Saving checkpoint... 
Iteration: 1407320027, states[0] = -95.001799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419836852, states[0] = -95.011740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433150389, states[0] = -80.838885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446246708, states[0] = -94.932096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459529617, states[0] = 17.825874, states[40]= 0.005889
Saving checkpoint... 
Iteration: 1472648461, states[0] = -77.654727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485929274, states[0] = -95.045118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499292792, states[0] = -94.981669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1512448598, states[0] = -94.916681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1525597502, states[0] = -37.929069, states[40]= 0.000164
Saving checkpoint... 
Iteration: 1538749661, states[0] = 6.908243, states[40]= 0.005419
Saving checkpoint... 
Iteration: 1552016822, states[0] = -62.799781, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1564617399, states[0] = -63.934695, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1577799967, states[0] = -42.466326, states[40]= 0.000086
Saving checkpoint... 
Iteration: 1590908742, states[0] = 23.224278, states[40]= 0.069175
Saving checkpoint... 
Iteration: 1604038953, states[0] = -95.296723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1617259415, states[0] = -95.320447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1630456435, states[0] = -95.318154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1643524414, states[0] = -75.135677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1656742061, states[0] = -94.658901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1669901508, states[0] = -44.690533, states[40]= 0.000062
Saving checkpoint... 
Iteration: 1683074524, states[0] = -13.423337, states[40]= 0.001917
Saving checkpoint... 
Iteration: 1696157798, states[0] = -95.320654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1707094653, states[0] = -36.618649, states[40]= 0.000196
Saving checkpoint... 
Iteration: 1718427992, states[0] = 17.025743, states[40]= 0.007149
Saving checkpoint... 
Iteration: 1730934444, states[0] = -95.293984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1744179543, states[0] = -95.340189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1757396834, states[0] = -95.352728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1770640141, states[0] = 11.520371, states[40]= 0.005863
Saving checkpoint... 
Iteration: 1783826235, states[0] = 17.709740, states[40]= 0.007539
Saving checkpoint... 
Iteration: 1797033311, states[0] = 14.761731, states[40]= 0.006395
Saving checkpoint... 
Iteration: 1810163419, states[0] = -94.574752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1823298814, states[0] = -95.025900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1836597295, states[0] = -21.928206, states[40]= 0.000818
Saving checkpoint... 
Iteration: 1849708699, states[0] = -94.888356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1862908547, states[0] = -95.052304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1876161217, states[0] = -93.575854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1889397080, states[0] = -95.042156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1901460478, states[0] = -95.055090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1913293568, states[0] = -94.984971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1925010889, states[0] = 21.623075, states[40]= 0.042204
Saving checkpoint... 
Iteration: 1936107506, states[0] = -30.714183, states[40]= 0.000401
Saving checkpoint... 
Iteration: 1948475440, states[0] = -95.054346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1961631886, states[0] = -56.304184, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1974766113, states[0] = -94.955976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1987318535, states[0] = -95.000741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1996430057, states[0] = -95.045164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2009558325, states[0] = 7.128163, states[40]= 0.004727
Saving checkpoint... 
Iteration: 2022649876, states[0] = -79.994707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035601402, states[0] = -24.539001, states[40]= 0.000683
Saving checkpoint... 
Iteration: 2048710037, states[0] = -94.871754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2061404233, states[0] = -95.038307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2072421769, states[0] = -95.042929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2085309072, states[0] = -94.993882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2097846179, states[0] = -95.016090, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.932289
 - CaMKt in component CaMK (millimolar): 0.006888
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.593347
 - nass in component intracellular_ions (millimolar): 6.593407
 - ki in component intracellular_ions (millimolar): 145.385060
 - kss in component intracellular_ions (millimolar): 145.385040
 - cansr in component intracellular_ions (millimolar): 1.306122
 - cajsr in component intracellular_ions (millimolar): 1.268585
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003607
 - hf in component INa (dimensionless): 0.880528
 - hs in component INa (dimensionless): 0.880523
 - j in component INa (dimensionless): 0.880494
 - hsp in component INa (dimensionless): 0.726824
 - jp in component INa (dimensionless): 0.880475
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711699
 - hLp in component INaL (dimensionless): 0.455846
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.626377
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.702540
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.940027
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999901
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001570
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.314628
 - xs1 in component IKs (dimensionless): 0.232979
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997329
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:47:23 (7632): called boinc_finish(0)

</stderr_txt>
]]>


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