𝕏

Task 55435984

Name HuVeMOp_20240630132542215956_ORdGradInc_k_25-Pueyo_APDR-conf_405_1
Workunit 26324294
Created 30 Jun 2024, 11:25:47 UTC
Sent 30 Jun 2024, 12:52:40 UTC
Report deadline 3 Jul 2024, 22:28:40 UTC
Received 2 Jul 2024, 3:34:11 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 231681
Run time 1 hours 22 min 37 sec
CPU time 1 hours 16 min 7 sec
Validate state Valid
Credit 61.62
Device peak FLOPS 5.60 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.02 MB
Peak swap size 32.57 GB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630132542215956_ORdGradInc_k_25-Pueyo_APDR-conf_405.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630132542215956_ORdGradInc_k_25-Pueyo_APDR-conf_405_1_r434471083_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630132542215956_ORdGradInc_k_25-Pueyo_APDR-conf_405_1_r434471083_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 91.739239
     * GNaL_b in INaL: 0.005300
     * Gto_b in Ito: 0.077752
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033315
     * GKs_b in IKs: 0.002036
     * GK1_b in IK1: 0.180776
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 74.672943
     * GKb_b in IKb: 0.003903
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.045373
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 27985272, states[0] = -95.226824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56114562, states[0] = -40.146727, states[40]= 0.000115


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630132542215956_ORdGradInc_k_25-Pueyo_APDR-conf_405.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630132542215956_ORdGradInc_k_25-Pueyo_APDR-conf_405_1_r434471083_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630132542215956_ORdGradInc_k_25-Pueyo_APDR-conf_405_1_r434471083_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 91.739239
     * GNaL_b in INaL: 0.005300
     * Gto_b in Ito: 0.077752
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033315
     * GKs_b in IKs: 0.002036
     * GK1_b in IK1: 0.180776
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 74.672943
     * GKb_b in IKb: 0.003903
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.045373
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 56114562
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -40.146727 (After loading)
 - states[40]: 0.000115 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630132542215956_ORdGradInc_k_25-Pueyo_APDR-conf_405.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630132542215956_ORdGradInc_k_25-Pueyo_APDR-conf_405_1_r434471083_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630132542215956_ORdGradInc_k_25-Pueyo_APDR-conf_405_1_r434471083_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 91.739239
     * GNaL_b in INaL: 0.005300
     * Gto_b in Ito: 0.077752
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033315
     * GKs_b in IKs: 0.002036
     * GK1_b in IK1: 0.180776
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 74.672943
     * GKb_b in IKb: 0.003903
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.045373
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 56114562
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -40.146727 (After loading)
 - states[40]: 0.000115 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 84405148, states[0] = -95.166771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111582880, states[0] = -7.560626, states[40]= 0.002870


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630132542215956_ORdGradInc_k_25-Pueyo_APDR-conf_405.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630132542215956_ORdGradInc_k_25-Pueyo_APDR-conf_405_1_r434471083_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630132542215956_ORdGradInc_k_25-Pueyo_APDR-conf_405_1_r434471083_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 91.739239
     * GNaL_b in INaL: 0.005300
     * Gto_b in Ito: 0.077752
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033315
     * GKs_b in IKs: 0.002036
     * GK1_b in IK1: 0.180776
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 74.672943
     * GKb_b in IKb: 0.003903
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.045373
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 111582880
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -7.560626 (After loading)
 - states[40]: 0.002870 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 139040642, states[0] = 14.393252, states[40]= 0.005322
Saving checkpoint... 
Iteration: 164944017, states[0] = -95.165623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191027250, states[0] = 19.169418, states[40]= 0.006764


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630132542215956_ORdGradInc_k_25-Pueyo_APDR-conf_405.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630132542215956_ORdGradInc_k_25-Pueyo_APDR-conf_405_1_r434471083_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630132542215956_ORdGradInc_k_25-Pueyo_APDR-conf_405_1_r434471083_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 91.739239
     * GNaL_b in INaL: 0.005300
     * Gto_b in Ito: 0.077752
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033315
     * GKs_b in IKs: 0.002036
     * GK1_b in IK1: 0.180776
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 74.672943
     * GKb_b in IKb: 0.003903
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.045373
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 191027250
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 19.169418 (After loading)
 - states[40]: 0.006764 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 217921250, states[0] = -95.160790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244661904, states[0] = -94.725134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271439055, states[0] = -95.163915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298108286, states[0] = -32.010308, states[40]= 0.000343
Saving checkpoint... 
Iteration: 324764378, states[0] = -95.087769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351504958, states[0] = 28.851238, states[40]= 0.138648
Saving checkpoint... 
Iteration: 378183466, states[0] = -94.974202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404952571, states[0] = -95.165968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430835844, states[0] = -95.134264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456334039, states[0] = -95.133434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482689506, states[0] = -94.985657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509683181, states[0] = -94.973566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536883779, states[0] = -95.151437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563858696, states[0] = -95.143381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591028147, states[0] = 18.895054, states[40]= 0.006581
Saving checkpoint... 
Iteration: 618482646, states[0] = -95.169791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646071560, states[0] = 0.457018, states[40]= 0.004329
Saving checkpoint... 
Iteration: 673313966, states[0] = -95.123201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700067785, states[0] = 2.519681, states[40]= 0.004555
Saving checkpoint... 
Iteration: 726499395, states[0] = -95.171490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753200326, states[0] = -95.004920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779870741, states[0] = -95.147356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806338800, states[0] = -95.135355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831179189, states[0] = -94.965294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856163480, states[0] = -94.815469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881187195, states[0] = -94.981084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906357489, states[0] = -95.142749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932727406, states[0] = -95.046217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959219165, states[0] = -95.034706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985070985, states[0] = 0.783926, states[40]= 0.004370
Saving checkpoint... 
Iteration: 1010770700, states[0] = -95.092971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035839318, states[0] = -95.135449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062188420, states[0] = -94.983291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088790410, states[0] = -95.108239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114882192, states[0] = -95.150653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141431420, states[0] = -95.162036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167744549, states[0] = -95.067137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194231900, states[0] = -95.051947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219566158, states[0] = 3.355944, states[40]= 0.004629
Saving checkpoint... 
Iteration: 1246334560, states[0] = -95.133220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273221882, states[0] = -95.038420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299911323, states[0] = -95.157908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326601541, states[0] = -25.241011, states[40]= 0.000649
Saving checkpoint... 
Iteration: 1353309611, states[0] = -95.120344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379820329, states[0] = -95.126219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405121213, states[0] = -45.528065, states[40]= 0.000051
Saving checkpoint... 
Iteration: 1430608846, states[0] = -32.574058, states[40]= 0.000321
Saving checkpoint... 
Iteration: 1456096295, states[0] = -20.004640, states[40]= 0.000945
Saving checkpoint... 
Iteration: 1481181227, states[0] = -94.969122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506950710, states[0] = 7.008675, states[40]= 0.005459
Saving checkpoint... 
Iteration: 1533181090, states[0] = -95.271240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1559238309, states[0] = -94.698361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1584459558, states[0] = -95.242274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1610685033, states[0] = -95.409730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1637360971, states[0] = -95.393859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1663171479, states[0] = -95.402125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1689425134, states[0] = -79.844131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1716099025, states[0] = -41.686786, states[40]= 0.000095
Saving checkpoint... 
Iteration: 1742986139, states[0] = -95.411961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1769251965, states[0] = -95.225000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1795787831, states[0] = -95.412958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1821424500, states[0] = -95.190680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1847421439, states[0] = -95.173785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1874113874, states[0] = -38.185953, states[40]= 0.000153
Saving checkpoint... 
Iteration: 1900913541, states[0] = -95.160832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1927268735, states[0] = -95.092003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1953599465, states[0] = -23.208429, states[40]= 0.000750
Saving checkpoint... 
Iteration: 1979973702, states[0] = -95.168175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2006051793, states[0] = 9.901526, states[40]= 0.004989
Saving checkpoint... 
Iteration: 2031251446, states[0] = -95.074132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2057568736, states[0] = 2.016925, states[40]= 0.004506
Saving checkpoint... 
Iteration: 2084086997, states[0] = -10.946600, states[40]= 0.002159
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.046601
 - CaMKt in component CaMK (millimolar): 0.006584
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.431621
 - nass in component intracellular_ions (millimolar): 6.431680
 - ki in component intracellular_ions (millimolar): 145.551219
 - kss in component intracellular_ions (millimolar): 145.551200
 - cansr in component intracellular_ions (millimolar): 1.290182
 - cajsr in component intracellular_ions (millimolar): 1.253103
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003566
 - hf in component INa (dimensionless): 0.882490
 - hs in component INa (dimensionless): 0.882486
 - j in component INa (dimensionless): 0.882462
 - hsp in component INa (dimensionless): 0.730542
 - jp in component INa (dimensionless): 0.882447
 - mL in component INaL (dimensionless): 0.000048
 - hL in component INaL (dimensionless): 0.715546
 - hLp in component INaL (dimensionless): 0.461966
 - a in component Ito (dimensionless): 0.000617
 - iF in component Ito (dimensionless): 0.999873
 - iS in component Ito (dimensionless): 0.629033
 - ap in component Ito (dimensionless): 0.000315
 - iFp in component Ito (dimensionless): 0.999873
 - iSp in component Ito (dimensionless): 0.705654
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.938692
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999899
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001525
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.317472
 - xs1 in component IKs (dimensionless): 0.232535
 - xs2 in component IKs (dimensionless): 0.000086
 - xk1 in component IK1 (dimensionless): 0.997299
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:03:55 (35249): called boinc_finish(0)

</stderr_txt>
]]>