𝕏

Task 55435822

Name HuVeMOp_20240630131105441404_ORdGradInc_k_25-Pueyo_APDR-conf_189_0
Workunit 26324228
Created 30 Jun 2024, 11:11:42 UTC
Sent 30 Jun 2024, 12:52:40 UTC
Report deadline 3 Jul 2024, 22:28:40 UTC
Received 30 Jun 2024, 18:27:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241093
Run time 3 hours 9 min 28 sec
CPU time 3 hours 6 min
Validate state Valid
Credit 62.95
Device peak FLOPS 3.91 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.03 MB
Peak swap size 5.27 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630131105441404_ORdGradInc_k_25-Pueyo_APDR-conf_189.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630131105441404_ORdGradInc_k_25-Pueyo_APDR-conf_189_0_r1472460538_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630131105441404_ORdGradInc_k_25-Pueyo_APDR-conf_189_0_r1472460538_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 92.821419
     * GNaL_b in INaL: 0.007105
     * Gto_b in Ito: 0.071334
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032100
     * GKs_b in IKs: 0.002109
     * GK1_b in IK1: 0.178016
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 75.140562
     * GKb_b in IKb: 0.003929
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.045557
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12621666, states[0] = -45.653004, states[40]= 0.000051
Saving checkpoint... 
Iteration: 25011109, states[0] = 24.192481, states[40]= 0.039892
Saving checkpoint... 
Iteration: 37340156, states[0] = -95.226367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49778727, states[0] = -95.174522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61905625, states[0] = -95.223581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74257510, states[0] = -95.139135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86485166, states[0] = -95.226169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98503851, states[0] = 34.051472, states[40]= 0.131619
Saving checkpoint... 
Iteration: 110721288, states[0] = -95.085379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122904022, states[0] = -95.205812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135018148, states[0] = 23.133971, states[40]= 0.012570
Saving checkpoint... 
Iteration: 147167968, states[0] = -94.626845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159474087, states[0] = -95.216152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171765168, states[0] = -95.132958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183997725, states[0] = -95.218271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196065886, states[0] = 6.028744, states[40]= 0.004789
Saving checkpoint... 
Iteration: 208183232, states[0] = -95.014854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220234502, states[0] = -95.098699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232669245, states[0] = -94.746342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244850188, states[0] = -95.185607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257040766, states[0] = 16.196824, states[40]= 0.005416
Saving checkpoint... 
Iteration: 269186048, states[0] = -95.020967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281382969, states[0] = -95.196856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293190783, states[0] = -95.030160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305214726, states[0] = -95.070682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317551740, states[0] = 11.963546, states[40]= 0.005064
Saving checkpoint... 
Iteration: 329870476, states[0] = -95.192900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342210342, states[0] = -95.063781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354537058, states[0] = 17.555085, states[40]= 0.005657
Saving checkpoint... 
Iteration: 366962675, states[0] = -95.213421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379133746, states[0] = -50.876121, states[40]= 0.000023
Saving checkpoint... 
Iteration: 391321593, states[0] = -95.172220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403666510, states[0] = -94.357045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415912863, states[0] = -95.204460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428133312, states[0] = -50.377667, states[40]= 0.000025
Saving checkpoint... 
Iteration: 440297997, states[0] = -95.158116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452509291, states[0] = 25.419520, states[40]= 0.059288
Saving checkpoint... 
Iteration: 464766895, states[0] = -95.133639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477086703, states[0] = -5.639009, states[40]= 0.003226
Saving checkpoint... 
Iteration: 489392020, states[0] = -95.199284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501431353, states[0] = -95.208219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513204428, states[0] = -95.054021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525123753, states[0] = -40.000824, states[40]= 0.000124
Saving checkpoint... 
Iteration: 536907266, states[0] = -95.203115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548808957, states[0] = -95.165012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560746119, states[0] = -95.112341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572785341, states[0] = -95.149016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584789575, states[0] = -95.152162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596899901, states[0] = -95.201291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608885605, states[0] = -95.197433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621032601, states[0] = 19.106808, states[40]= 0.006098
Saving checkpoint... 
Iteration: 633073637, states[0] = 2.333936, states[40]= 0.004496
Saving checkpoint... 
Iteration: 645293660, states[0] = -95.155047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657595613, states[0] = -13.071323, states[40]= 0.001735
Saving checkpoint... 
Iteration: 669963986, states[0] = -95.213454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682387030, states[0] = -95.197804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694434023, states[0] = -95.208621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706509570, states[0] = 25.292311, states[40]= 0.055812
Saving checkpoint... 
Iteration: 718388637, states[0] = -95.198239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730364994, states[0] = -95.190830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742542271, states[0] = 15.633914, states[40]= 0.005342
Saving checkpoint... 
Iteration: 754289967, states[0] = -95.152363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766151459, states[0] = -74.768686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778362692, states[0] = -95.189994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790494451, states[0] = -95.217103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802530224, states[0] = 19.887955, states[40]= 0.006436
Saving checkpoint... 
Iteration: 814652772, states[0] = -77.149402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826799158, states[0] = -95.158697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839019412, states[0] = 22.876331, states[40]= 0.011054
Saving checkpoint... 
Iteration: 851242505, states[0] = -95.108017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863196002, states[0] = -95.039318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875488738, states[0] = -95.216443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887669470, states[0] = -94.763693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899493640, states[0] = -95.216963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911132328, states[0] = -49.255465, states[40]= 0.000030
Saving checkpoint... 
Iteration: 922753015, states[0] = -95.119721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934704005, states[0] = -95.053102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946822802, states[0] = -95.172580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958891901, states[0] = -95.199020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970957438, states[0] = -95.212362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983074233, states[0] = 2.026888, states[40]= 0.004464
Saving checkpoint... 
Iteration: 995066985, states[0] = 5.540716, states[40]= 0.004758
Saving checkpoint... 
Iteration: 1007116372, states[0] = -32.689932, states[40]= 0.000335
Saving checkpoint... 
Iteration: 1019593363, states[0] = -11.055078, states[40]= 0.002096
Saving checkpoint... 
Iteration: 1031580283, states[0] = -1.349398, states[40]= 0.004024
Saving checkpoint... 
Iteration: 1043891239, states[0] = -95.198797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055662289, states[0] = -92.473967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067755430, states[0] = -95.122173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079894751, states[0] = -95.199723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091591222, states[0] = -9.212194, states[40]= 0.002466
Saving checkpoint... 
Iteration: 1103786012, states[0] = -95.149261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115821752, states[0] = -95.171944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128067443, states[0] = 5.330929, states[40]= 0.004744
Saving checkpoint... 
Iteration: 1140339593, states[0] = -95.180596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152284989, states[0] = -95.148460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164357488, states[0] = -95.187899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176624469, states[0] = -40.736489, states[40]= 0.000111
Saving checkpoint... 
Iteration: 1190311899, states[0] = -95.166434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202840737, states[0] = -95.181071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214702664, states[0] = -95.050701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226307438, states[0] = -95.163758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238370989, states[0] = -95.192614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250517268, states[0] = 23.347933, states[40]= 0.013958
Saving checkpoint... 
Iteration: 1262890659, states[0] = -95.198530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274988435, states[0] = -95.216212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287076411, states[0] = 0.869631, states[40]= 0.004333
Saving checkpoint... 
Iteration: 1298910197, states[0] = -95.203420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310748602, states[0] = -95.114752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322951186, states[0] = -95.211233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335072120, states[0] = 3.099176, states[40]= 0.004569
Saving checkpoint... 
Iteration: 1346953375, states[0] = -95.211562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358963779, states[0] = -95.213084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371246189, states[0] = -95.112018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383394634, states[0] = -95.199542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395737773, states[0] = -95.102038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408053720, states[0] = 11.173614, states[40]= 0.005028
Saving checkpoint... 
Iteration: 1419846357, states[0] = -95.183371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432077207, states[0] = 0.431655, states[40]= 0.004278
Saving checkpoint... 
Iteration: 1444112587, states[0] = -29.055657, states[40]= 0.000498
Saving checkpoint... 
Iteration: 1456368379, states[0] = -95.191634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470969508, states[0] = -95.213810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482942444, states[0] = -95.209723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494643283, states[0] = -62.472303, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1506687010, states[0] = -18.360557, states[40]= 0.001160
Saving checkpoint... 
Iteration: 1518187818, states[0] = -95.315953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1529914621, states[0] = -95.368159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1541808638, states[0] = -44.400325, states[40]= 0.000067
Saving checkpoint... 
Iteration: 1553528541, states[0] = -72.527698, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1565426387, states[0] = 19.767085, states[40]= 0.008301
Saving checkpoint... 
Iteration: 1577179335, states[0] = -12.981547, states[40]= 0.001986
Saving checkpoint... 
Iteration: 1588908383, states[0] = -45.072320, states[40]= 0.000061
Saving checkpoint... 
Iteration: 1600771207, states[0] = -95.447434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1612542513, states[0] = 12.285514, states[40]= 0.006064
Saving checkpoint... 
Iteration: 1624384103, states[0] = -95.341708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636420861, states[0] = -95.399857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1648377757, states[0] = -95.329802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1660429997, states[0] = -95.411318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1672588977, states[0] = -23.639638, states[40]= 0.000777
Saving checkpoint... 
Iteration: 1684508970, states[0] = 26.198951, states[40]= 0.062055
Saving checkpoint... 
Iteration: 1696296164, states[0] = -31.441130, states[40]= 0.000384
Saving checkpoint... 
Iteration: 1708144293, states[0] = -95.426770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1720078270, states[0] = -95.331251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1732096842, states[0] = -95.365420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1744137439, states[0] = -95.419799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1756163838, states[0] = -95.444085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1768579875, states[0] = -13.834605, states[40]= 0.001831
Saving checkpoint... 
Iteration: 1781144026, states[0] = 11.493139, states[40]= 0.005972
Saving checkpoint... 
Iteration: 1793344382, states[0] = -95.426867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1805550298, states[0] = 11.538433, states[40]= 0.005160
Saving checkpoint... 
Iteration: 1818124246, states[0] = -43.407512, states[40]= 0.000076
Saving checkpoint... 
Iteration: 1830671703, states[0] = -94.967507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1842079631, states[0] = -1.615920, states[40]= 0.004005
Saving checkpoint... 
Iteration: 1854261678, states[0] = -95.139932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1866702736, states[0] = -95.058716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1879062422, states[0] = 7.425151, states[40]= 0.004872
Saving checkpoint... 
Iteration: 1891477369, states[0] = -95.218423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1903970609, states[0] = -95.216355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1916286946, states[0] = -95.151376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1928217441, states[0] = -95.075264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1940081264, states[0] = -1.986989, states[40]= 0.003922
Saving checkpoint... 
Iteration: 1952418629, states[0] = -95.205541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1964789272, states[0] = -95.151652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1977158651, states[0] = -88.206755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1988940540, states[0] = -95.209315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2001330858, states[0] = -95.176219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2013835515, states[0] = -95.178372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2026065259, states[0] = 6.317914, states[40]= 0.004805
Saving checkpoint... 
Iteration: 2038137746, states[0] = -55.573171, states[40]= 0.000011
Saving checkpoint... 
Iteration: 2050261820, states[0] = -95.128063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2062359717, states[0] = -95.188263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2074678678, states[0] = -94.997885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2087120248, states[0] = -36.476925, states[40]= 0.000204
Saving checkpoint... 
Iteration: 2099275402, states[0] = -95.140271, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.092866
 - CaMKt in component CaMK (millimolar): 0.006473
 - cass in component intracellular_ions (millimolar): 0.000072
 - nai in component intracellular_ions (millimolar): 6.394781
 - nass in component intracellular_ions (millimolar): 6.394840
 - ki in component intracellular_ions (millimolar): 145.591932
 - kss in component intracellular_ions (millimolar): 145.591912
 - cansr in component intracellular_ions (millimolar): 1.276061
 - cajsr in component intracellular_ions (millimolar): 1.238388
 - cai in component intracellular_ions (millimolar): 0.000073
 - m in component INa (dimensionless): 0.003549
 - hf in component INa (dimensionless): 0.883276
 - hs in component INa (dimensionless): 0.883272
 - j in component INa (dimensionless): 0.883248
 - hsp in component INa (dimensionless): 0.732035
 - jp in component INa (dimensionless): 0.883232
 - mL in component INaL (dimensionless): 0.000048
 - hL in component INaL (dimensionless): 0.714977
 - hLp in component INaL (dimensionless): 0.457855
 - a in component Ito (dimensionless): 0.000615
 - iF in component Ito (dimensionless): 0.999874
 - iS in component Ito (dimensionless): 0.621047
 - ap in component Ito (dimensionless): 0.000314
 - iFp in component Ito (dimensionless): 0.999874
 - iSp in component Ito (dimensionless): 0.695620
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.930806
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999872
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001472
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.336119
 - xs1 in component IKs (dimensionless): 0.248133
 - xs2 in component IKs (dimensionless): 0.000086
 - xk1 in component IK1 (dimensionless): 0.997286
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:26:45 (10896): called boinc_finish(0)

</stderr_txt>
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