𝕏

Task 55434386

Name HuVeMOp_20240630130118581586_ORdGradInc_k_25-Pueyo_APDR-conf_198_0
Workunit 26323516
Created 30 Jun 2024, 11:01:46 UTC
Sent 30 Jun 2024, 12:38:50 UTC
Report deadline 3 Jul 2024, 22:14:50 UTC
Received 1 Jul 2024, 15:07:51 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232691
Run time 1 hours 30 min 23 sec
CPU time 1 hours 29 min 18 sec
Validate state Valid
Credit 61.43
Device peak FLOPS 4.35 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.88 MB
Peak swap size 6.38 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630130118581586_ORdGradInc_k_25-Pueyo_APDR-conf_198.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630130118581586_ORdGradInc_k_25-Pueyo_APDR-conf_198_0_r118754155_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630130118581586_ORdGradInc_k_25-Pueyo_APDR-conf_198_0_r118754155_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 92.502304
     * GNaL_b in INaL: 0.006905
     * Gto_b in Ito: 0.071930
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030392
     * GKs_b in IKs: 0.001847
     * GK1_b in IK1: 0.171819
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 67.595988
     * GKb_b in IKb: 0.003836
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.047950
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10385418, states[0] = -95.196321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24929381, states[0] = -95.175019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39296630, states[0] = -95.104536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53755628, states[0] = -95.057380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68417627, states[0] = -95.138326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82229484, states[0] = -95.013623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97069117, states[0] = 5.201314, states[40]= 0.004730
Saving checkpoint... 
Iteration: 111704515, states[0] = -94.969139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126445134, states[0] = -95.133706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141094268, states[0] = -9.853354, states[40]= 0.002327
Saving checkpoint... 
Iteration: 156023881, states[0] = 21.916221, states[40]= 0.007863
Saving checkpoint... 
Iteration: 170504461, states[0] = 31.701829, states[40]= 0.139402
Saving checkpoint... 
Iteration: 185209988, states[0] = -94.975266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199479934, states[0] = -95.136834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214277090, states[0] = -95.059140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228747172, states[0] = -95.028247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243219169, states[0] = -94.989729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257954290, states[0] = -95.132884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272555594, states[0] = 10.976357, states[40]= 0.004989
Saving checkpoint... 
Iteration: 287087815, states[0] = -4.865989, states[40]= 0.003376
Saving checkpoint... 
Iteration: 301122716, states[0] = -35.336146, states[40]= 0.000256
Saving checkpoint... 
Iteration: 315905022, states[0] = -95.122746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330587468, states[0] = -4.626268, states[40]= 0.003425
Saving checkpoint... 
Iteration: 345382325, states[0] = -95.116295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359829725, states[0] = -95.094830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374630645, states[0] = -43.016679, states[40]= 0.000085
Saving checkpoint... 
Iteration: 389099086, states[0] = -13.890714, states[40]= 0.001603
Saving checkpoint... 
Iteration: 403809820, states[0] = -95.083371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418157056, states[0] = -75.201117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432703384, states[0] = -94.963348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447286192, states[0] = -95.066473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462088763, states[0] = -5.530370, states[40]= 0.003240
Saving checkpoint... 
Iteration: 476377438, states[0] = -95.114647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491172242, states[0] = -94.219638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505903436, states[0] = -95.122225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520228805, states[0] = -95.003891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534632403, states[0] = -44.809376, states[40]= 0.000064
Saving checkpoint... 
Iteration: 549355149, states[0] = -95.106440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559541455, states[0] = 16.312764, states[40]= 0.005328
Saving checkpoint... 
Iteration: 574183390, states[0] = -94.910206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588647362, states[0] = -61.460581, states[40]= 0.000004
Saving checkpoint... 
Iteration: 602950918, states[0] = -95.132089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617546201, states[0] = 14.566579, states[40]= 0.005160
Saving checkpoint... 
Iteration: 631793081, states[0] = -95.071714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646007518, states[0] = 26.483075, states[40]= 0.087465
Saving checkpoint... 
Iteration: 659867017, states[0] = -95.110943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674417017, states[0] = -95.125427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688731304, states[0] = -95.007330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703315670, states[0] = -95.086803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717353470, states[0] = -95.105660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727613095, states[0] = -26.502378, states[40]= 0.000662
Saving checkpoint... 
Iteration: 741908060, states[0] = -95.123265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756556808, states[0] = 10.499484, states[40]= 0.004972
Saving checkpoint... 
Iteration: 770857700, states[0] = -95.107344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785413818, states[0] = -95.124628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799723087, states[0] = -94.995343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814317284, states[0] = -95.087699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828417822, states[0] = -95.125526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840135031, states[0] = -47.556506, states[40]= 0.000042
Saving checkpoint... 
Iteration: 853697784, states[0] = -94.953064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868281254, states[0] = -95.062179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882945889, states[0] = -95.131080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897091110, states[0] = -7.259999, states[40]= 0.002873
Saving checkpoint... 
Iteration: 911475870, states[0] = -95.135627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925426509, states[0] = -95.127358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940208719, states[0] = -94.972266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954409338, states[0] = -95.123464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968952307, states[0] = -95.132119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983422372, states[0] = -95.126448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998130808, states[0] = -43.180867, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1012444489, states[0] = -95.130764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026772547, states[0] = -95.054406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041297844, states[0] = -95.074971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055593961, states[0] = -9.512552, states[40]= 0.002396
Saving checkpoint... 
Iteration: 1070135761, states[0] = -48.333059, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1084431318, states[0] = -95.128252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098985703, states[0] = -95.136765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113418748, states[0] = -95.125579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127594990, states[0] = -10.362205, states[40]= 0.002224
Saving checkpoint... 
Iteration: 1141987091, states[0] = -95.136908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156549270, states[0] = 13.411799, states[40]= 0.005090
Saving checkpoint... 
Iteration: 1170740377, states[0] = -95.019200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185118182, states[0] = -31.136770, states[40]= 0.000430
Saving checkpoint... 
Iteration: 1199469078, states[0] = -95.134545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214043489, states[0] = 15.571267, states[40]= 0.005245
Saving checkpoint... 
Iteration: 1228189034, states[0] = -94.934505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242688439, states[0] = -94.932842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257011126, states[0] = 24.728689, states[40]= 0.039576
Saving checkpoint... 
Iteration: 1271780655, states[0] = -95.061451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286180095, states[0] = -94.869893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300729215, states[0] = -95.004049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314926104, states[0] = -95.127062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329702728, states[0] = -94.961702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343766647, states[0] = -95.048623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358459006, states[0] = -95.132975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372754192, states[0] = -95.035590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384949749, states[0] = -95.131468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399481702, states[0] = -95.136111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413750378, states[0] = -95.031239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428332404, states[0] = -95.095620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442715783, states[0] = -94.983633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457099688, states[0] = -14.423092, states[40]= 0.001526
Saving checkpoint... 
Iteration: 1471390872, states[0] = -95.118260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486018370, states[0] = 23.209066, states[40]= 0.011909
Saving checkpoint... 
Iteration: 1500420415, states[0] = -49.664298, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1514717715, states[0] = 23.394385, states[40]= 0.014561
Saving checkpoint... 
Iteration: 1529363769, states[0] = -95.345698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1543606937, states[0] = -38.898013, states[40]= 0.000158
Saving checkpoint... 
Iteration: 1557619511, states[0] = 22.531961, states[40]= 0.011979
Saving checkpoint... 
Iteration: 1571718031, states[0] = 22.967881, states[40]= 0.013789
Saving checkpoint... 
Iteration: 1586251124, states[0] = -94.903243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600410113, states[0] = -95.306602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1614800053, states[0] = -95.291383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628943579, states[0] = -95.350956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1643554177, states[0] = -95.104678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1657715013, states[0] = -95.316228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1672089705, states[0] = -95.274198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1685712666, states[0] = 24.582221, states[40]= 0.030082
Saving checkpoint... 
Iteration: 1700104064, states[0] = 34.040046, states[40]= 0.119086
Saving checkpoint... 
Iteration: 1713703010, states[0] = -35.783505, states[40]= 0.000241
Saving checkpoint... 
Iteration: 1728057701, states[0] = 4.846807, states[40]= 0.005357
Saving checkpoint... 
Iteration: 1742261592, states[0] = -95.206190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1756451752, states[0] = -95.360215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1770701353, states[0] = -34.035013, states[40]= 0.000301
Saving checkpoint... 
Iteration: 1784891116, states[0] = -95.277071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1799540244, states[0] = -87.928048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1813830986, states[0] = -95.132966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1828265637, states[0] = -95.074002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1842743724, states[0] = -95.040931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856944294, states[0] = -95.141959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1871000615, states[0] = 35.429822, states[40]= 0.002259
Saving checkpoint... 
Iteration: 1885191614, states[0] = -94.945673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1900014712, states[0] = 23.901278, states[40]= 0.019700
Saving checkpoint... 
Iteration: 1910084378, states[0] = -2.710712, states[40]= 0.003791
Saving checkpoint... 
Iteration: 1924843474, states[0] = -95.102303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1935007590, states[0] = 26.414010, states[40]= 0.086182
Saving checkpoint... 
Iteration: 1949630772, states[0] = -43.212497, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1963666063, states[0] = -90.521179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1978129330, states[0] = -41.728017, states[40]= 0.000103
Saving checkpoint... 
Iteration: 1992827307, states[0] = -95.092860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2007334533, states[0] = -95.096484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022041830, states[0] = 16.175304, states[40]= 0.005311
Saving checkpoint... 
Iteration: 2036605973, states[0] = -20.075782, states[40]= 0.000972
Saving checkpoint... 
Iteration: 2051318942, states[0] = -95.087988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2065750744, states[0] = -95.031286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2080229239, states[0] = -95.003627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2094718690, states[0] = -94.987844, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.013669
 - CaMKt in component CaMK (millimolar): 0.006754
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.588297
 - nass in component intracellular_ions (millimolar): 6.588355
 - ki in component intracellular_ions (millimolar): 145.394386
 - kss in component intracellular_ions (millimolar): 145.394367
 - cansr in component intracellular_ions (millimolar): 1.292637
 - cajsr in component intracellular_ions (millimolar): 1.254360
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003578
 - hf in component INa (dimensionless): 0.881927
 - hs in component INa (dimensionless): 0.881923
 - j in component INa (dimensionless): 0.881898
 - hsp in component INa (dimensionless): 0.729474
 - jp in component INa (dimensionless): 0.881880
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711599
 - hLp in component INaL (dimensionless): 0.451612
 - a in component Ito (dimensionless): 0.000619
 - iF in component Ito (dimensionless): 0.999872
 - iS in component Ito (dimensionless): 0.615689
 - ap in component Ito (dimensionless): 0.000315
 - iFp in component Ito (dimensionless): 0.999872
 - iSp in component Ito (dimensionless): 0.689250
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.928441
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999861
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001533
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.341676
 - xs1 in component IKs (dimensionless): 0.253703
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997308
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:59:33 (2364): called boinc_finish(0)

</stderr_txt>
]]>