𝕏

Task 55434318

Name HuVeMOp_20240630130118581586_ORdGradInc_k_25-Pueyo_APDR-conf_189_0
Workunit 26323482
Created 30 Jun 2024, 11:01:46 UTC
Sent 30 Jun 2024, 12:39:12 UTC
Report deadline 3 Jul 2024, 22:15:12 UTC
Received 30 Jun 2024, 20:24:16 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 2 hours 21 min 49 sec
CPU time 2 hours 13 min 23 sec
Validate state Valid
Credit 61.55
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.07 MB
Peak swap size 4.13 GB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630130118581586_ORdGradInc_k_25-Pueyo_APDR-conf_189.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630130118581586_ORdGradInc_k_25-Pueyo_APDR-conf_189_0_r599924381_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630130118581586_ORdGradInc_k_25-Pueyo_APDR-conf_189_0_r599924381_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 92.821419
     * GNaL_b in INaL: 0.007105
     * Gto_b in Ito: 0.071334
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032100
     * GKs_b in IKs: 0.002109
     * GK1_b in IK1: 0.178016
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 75.140562
     * GKb_b in IKb: 0.003929
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.045557
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 17071445, states[0] = 0.882859, states[40]= 0.004403
Saving checkpoint... 
Iteration: 18251935, states[0] = -95.208106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30455155, states[0] = -95.268660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43455196, states[0] = -95.249219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54521170, states[0] = 22.164090, states[40]= 0.009459
Saving checkpoint... 
Iteration: 67464736, states[0] = -95.231223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80659890, states[0] = -91.227978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93111814, states[0] = -28.890391, states[40]= 0.000506
Saving checkpoint... 
Iteration: 105870017, states[0] = -95.198297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117464396, states[0] = -95.217625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129637777, states[0] = -55.874408, states[40]= 0.000010
Saving checkpoint... 
Iteration: 142678469, states[0] = -95.000132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154827547, states[0] = -95.176667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167661582, states[0] = -91.948527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180471696, states[0] = -95.215324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193036074, states[0] = 17.899621, states[40]= 0.005737
Saving checkpoint... 
Iteration: 205677259, states[0] = -94.990753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218904039, states[0] = -95.202689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231523569, states[0] = 21.847686, states[40]= 0.008216
Saving checkpoint... 
Iteration: 244765144, states[0] = -95.132215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256675908, states[0] = -94.978874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270112732, states[0] = -29.197565, states[40]= 0.000491
Saving checkpoint... 
Iteration: 282951819, states[0] = -95.211874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295567562, states[0] = 5.275506, states[40]= 0.004740
Saving checkpoint... 
Iteration: 308710380, states[0] = -95.063867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320752281, states[0] = -95.119250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334137221, states[0] = -54.943143, states[40]= 0.000012
Saving checkpoint... 
Iteration: 347202077, states[0] = -95.050140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360606614, states[0] = -23.387952, states[40]= 0.000767
Saving checkpoint... 
Iteration: 373409457, states[0] = -95.203709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385689412, states[0] = -95.027518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398172481, states[0] = -94.916847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411508083, states[0] = 26.122759, states[40]= 0.076760
Saving checkpoint... 
Iteration: 423687216, states[0] = -95.023230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437562004, states[0] = 7.743488, states[40]= 0.004881
Saving checkpoint... 
Iteration: 450772306, states[0] = -95.138477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463523991, states[0] = 21.736163, states[40]= 0.008039
Saving checkpoint... 
Iteration: 476768760, states[0] = -95.135328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489599723, states[0] = -16.884283, states[40]= 0.001218
Saving checkpoint... 
Iteration: 502972275, states[0] = -95.214651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516414917, states[0] = -95.204865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529972159, states[0] = -95.214623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542787249, states[0] = -95.150468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555130495, states[0] = -47.196438, states[40]= 0.000042
Saving checkpoint... 
Iteration: 568229137, states[0] = -95.091310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580647717, states[0] = -68.673610, states[40]= 0.000001
Saving checkpoint... 
Iteration: 594193163, states[0] = -95.034358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607522349, states[0] = 22.167253, states[40]= 0.008814
Saving checkpoint... 
Iteration: 620238499, states[0] = -95.103317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633750322, states[0] = -95.116975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645846118, states[0] = -95.183654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658333081, states[0] = -95.177844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671015892, states[0] = 23.636087, states[40]= 0.016821
Saving checkpoint... 
Iteration: 683311248, states[0] = -95.166304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695931233, states[0] = -95.208100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707999573, states[0] = -95.217670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720534135, states[0] = 18.584419, states[40]= 0.005922
Saving checkpoint... 
Iteration: 732637759, states[0] = -55.584773, states[40]= 0.000011
Saving checkpoint... 
Iteration: 745195958, states[0] = -95.039299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758201805, states[0] = -95.049468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771184757, states[0] = -95.017893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783851430, states[0] = -95.185750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796908143, states[0] = -95.203193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808757360, states[0] = -95.124275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821528665, states[0] = 20.379256, states[40]= 0.006716
Saving checkpoint... 
Iteration: 833850956, states[0] = -95.185536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847068559, states[0] = 4.813670, states[40]= 0.004708
Saving checkpoint... 
Iteration: 859559096, states[0] = 8.974715, states[40]= 0.004936
Saving checkpoint... 
Iteration: 872375509, states[0] = -95.194255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885401782, states[0] = -95.201619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898637572, states[0] = -55.360899, states[40]= 0.000011
Saving checkpoint... 
Iteration: 911256876, states[0] = -95.123733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924601115, states[0] = -18.194341, states[40]= 0.001091
Saving checkpoint... 
Iteration: 937101020, states[0] = -18.104782, states[40]= 0.001099
Saving checkpoint... 
Iteration: 950131583, states[0] = -48.413566, states[40]= 0.000034
Saving checkpoint... 
Iteration: 963299899, states[0] = -95.159118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976174712, states[0] = -94.963713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988732878, states[0] = -95.096043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001875275, states[0] = -95.194117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014259155, states[0] = -95.125973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027170390, states[0] = -94.827368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040191036, states[0] = -95.030236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052999025, states[0] = -95.217444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066223502, states[0] = -95.083271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079621714, states[0] = -37.936051, states[40]= 0.000167
Saving checkpoint... 
Iteration: 1093183391, states[0] = -95.014535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105669455, states[0] = -94.762353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118205472, states[0] = -95.055459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130569708, states[0] = 4.271780, states[40]= 0.004668
Saving checkpoint... 
Iteration: 1143631904, states[0] = -48.775384, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1156995352, states[0] = -95.217016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170348058, states[0] = -95.184198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183399309, states[0] = -95.200852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196301683, states[0] = -95.160164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210097089, states[0] = -14.426169, states[40]= 0.001525
Saving checkpoint... 
Iteration: 1222583964, states[0] = -3.701606, states[40]= 0.003614
Saving checkpoint... 
Iteration: 1235074602, states[0] = 1.834829, states[40]= 0.004444
Saving checkpoint... 
Iteration: 1247849111, states[0] = -95.184589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261050931, states[0] = 12.284326, states[40]= 0.005080
Saving checkpoint... 
Iteration: 1273645579, states[0] = -65.576329, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1286359244, states[0] = -95.188492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299149947, states[0] = -72.186285, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1312002944, states[0] = 38.574037, states[40]= 0.113835
Saving checkpoint... 
Iteration: 1325255100, states[0] = -95.121704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337986016, states[0] = -95.215908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351085061, states[0] = -4.456994, states[40]= 0.003467
Saving checkpoint... 
Iteration: 1363801563, states[0] = -95.160004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376052408, states[0] = 11.698276, states[40]= 0.005051
Saving checkpoint... 
Iteration: 1389402287, states[0] = -95.201494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402179740, states[0] = -95.003054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415034977, states[0] = 18.292312, states[40]= 0.005837
Saving checkpoint... 
Iteration: 1427772674, states[0] = -95.138312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439900553, states[0] = -95.201039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451809197, states[0] = -95.164708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464419500, states[0] = -95.205381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476561258, states[0] = 8.062841, states[40]= 0.004896
Saving checkpoint... 
Iteration: 1489770428, states[0] = -95.136315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1501963792, states[0] = -95.251534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1513591607, states[0] = -23.935509, states[40]= 0.000750
Saving checkpoint... 
Iteration: 1525358658, states[0] = -95.254834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537405316, states[0] = -95.359778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1550699182, states[0] = -95.455233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1563526818, states[0] = -95.399751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1576118073, states[0] = -95.391572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1588052424, states[0] = -95.240307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1599916357, states[0] = 23.316899, states[40]= 0.017229
Saving checkpoint... 
Iteration: 1611403138, states[0] = -39.061145, states[40]= 0.000145
Saving checkpoint... 
Iteration: 1622106520, states[0] = 28.525201, states[40]= 0.095360
Saving checkpoint... 
Iteration: 1634348620, states[0] = -95.430250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1645522599, states[0] = 21.145705, states[40]= 0.009854
Saving checkpoint... 
Iteration: 1657547200, states[0] = 9.864859, states[40]= 0.005801
Saving checkpoint... 
Iteration: 1669154373, states[0] = -95.435992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1681005408, states[0] = -41.779879, states[40]= 0.000098
Saving checkpoint... 
Iteration: 1691852070, states[0] = -95.241782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1703090743, states[0] = -95.462620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1713758457, states[0] = -95.284110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1724575389, states[0] = -95.325335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1735549726, states[0] = 8.523798, states[40]= 0.005678
Saving checkpoint... 
Iteration: 1747007776, states[0] = -44.600156, states[40]= 0.000065
Saving checkpoint... 
Iteration: 1757753803, states[0] = 6.295870, states[40]= 0.005485
Saving checkpoint... 
Iteration: 1768399902, states[0] = -95.370423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1777640284, states[0] = -93.353760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1788191235, states[0] = -95.355799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1797634395, states[0] = 16.181824, states[40]= 0.006775
Saving checkpoint... 
Iteration: 1808126348, states[0] = -46.779827, states[40]= 0.000048
Saving checkpoint... 
Iteration: 1818889861, states[0] = -95.231372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1830608833, states[0] = -27.190043, states[40]= 0.000588
Saving checkpoint... 
Iteration: 1841552177, states[0] = 11.432017, states[40]= 0.005065
Saving checkpoint... 
Iteration: 1851811923, states[0] = -95.178831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1863172682, states[0] = -94.948902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1874180219, states[0] = -95.012031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1886071008, states[0] = 3.511373, states[40]= 0.004612
Saving checkpoint... 
Iteration: 1897142987, states[0] = -62.448614, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1909171674, states[0] = -94.898176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919982642, states[0] = -95.216836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932294155, states[0] = -95.155864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1945140961, states[0] = -59.582295, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1957043131, states[0] = 15.298993, states[40]= 0.005305
Saving checkpoint... 
Iteration: 1969379306, states[0] = -95.195229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1981649170, states[0] = -70.960588, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1993576588, states[0] = 0.766754, states[40]= 0.004321
Saving checkpoint... 
Iteration: 2005653254, states[0] = -78.073259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2017839809, states[0] = -95.180305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2030143595, states[0] = -62.889675, states[40]= 0.000003
Saving checkpoint... 
Iteration: 2041898297, states[0] = -95.200171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2053607975, states[0] = -24.676345, states[40]= 0.000707
Saving checkpoint... 
Iteration: 2066128016, states[0] = -44.480911, states[40]= 0.000063
Saving checkpoint... 
Iteration: 2078771224, states[0] = -95.136696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2089842549, states[0] = -95.181390, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.092866
 - CaMKt in component CaMK (millimolar): 0.006473
 - cass in component intracellular_ions (millimolar): 0.000072
 - nai in component intracellular_ions (millimolar): 6.394781
 - nass in component intracellular_ions (millimolar): 6.394840
 - ki in component intracellular_ions (millimolar): 145.591932
 - kss in component intracellular_ions (millimolar): 145.591912
 - cansr in component intracellular_ions (millimolar): 1.276061
 - cajsr in component intracellular_ions (millimolar): 1.238388
 - cai in component intracellular_ions (millimolar): 0.000073
 - m in component INa (dimensionless): 0.003549
 - hf in component INa (dimensionless): 0.883276
 - hs in component INa (dimensionless): 0.883272
 - j in component INa (dimensionless): 0.883248
 - hsp in component INa (dimensionless): 0.732035
 - jp in component INa (dimensionless): 0.883232
 - mL in component INaL (dimensionless): 0.000048
 - hL in component INaL (dimensionless): 0.714977
 - hLp in component INaL (dimensionless): 0.457855
 - a in component Ito (dimensionless): 0.000615
 - iF in component Ito (dimensionless): 0.999874
 - iS in component Ito (dimensionless): 0.621047
 - ap in component Ito (dimensionless): 0.000314
 - iFp in component Ito (dimensionless): 0.999874
 - iSp in component Ito (dimensionless): 0.695620
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.930806
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999872
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001472
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.336119
 - xs1 in component IKs (dimensionless): 0.248133
 - xs2 in component IKs (dimensionless): 0.000086
 - xk1 in component IK1 (dimensionless): 0.997286
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:24:02 (98500): called boinc_finish(0)

</stderr_txt>
]]>


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