𝕏

Task 55434266

Name HuVeMOp_20240630130118581586_ORdGradInc_k_25-Pueyo_APDR-conf_974_0
Workunit 26323456
Created 30 Jun 2024, 11:01:46 UTC
Sent 30 Jun 2024, 12:37:17 UTC
Report deadline 3 Jul 2024, 22:13:17 UTC
Received 1 Jul 2024, 13:33:31 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238614
Run time 2 hours 31 min 25 sec
CPU time 2 hours 30 min 51 sec
Validate state Valid
Credit 58.19
Device peak FLOPS 3.71 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.95 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.14.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630130118581586_ORdGradInc_k_25-Pueyo_APDR-conf_974.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630130118581586_ORdGradInc_k_25-Pueyo_APDR-conf_974_0_r330732461_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630130118581586_ORdGradInc_k_25-Pueyo_APDR-conf_974_0_r330732461_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.689408
     * GNaL_b in INaL: 0.007271
     * Gto_b in Ito: 0.081637
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033357
     * GKs_b in IKs: 0.001755
     * GK1_b in IK1: 0.157088
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 67.203149
     * GKb_b in IKb: 0.003746
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.027317
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11603024, states[0] = -23.441171, states[40]= 0.000765
Saving checkpoint... 
Iteration: 22454093, states[0] = -94.952811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33563140, states[0] = 6.429279, states[40]= 0.004849
Saving checkpoint... 
Iteration: 44947102, states[0] = -94.930601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57951405, states[0] = -94.925278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69373045, states[0] = -94.899065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80365156, states[0] = -94.893217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95357970, states[0] = -94.887619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107124959, states[0] = -42.153689, states[40]= 0.000100
Saving checkpoint... 
Iteration: 118769936, states[0] = -94.819607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130858059, states[0] = -94.884940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142966004, states[0] = -94.916265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154211440, states[0] = -94.728721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169508498, states[0] = 24.495645, states[40]= 0.075006
Saving checkpoint... 
Iteration: 180549401, states[0] = 12.565990, states[40]= 0.005039
Saving checkpoint... 
Iteration: 191688146, states[0] = -94.676926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202620096, states[0] = -37.116829, states[40]= 0.000205
Saving checkpoint... 
Iteration: 213915059, states[0] = -94.904240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225766363, states[0] = -94.813408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237411724, states[0] = -94.903233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250390222, states[0] = -94.896467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266503187, states[0] = 36.492806, states[40]= 0.144610
Saving checkpoint... 
Iteration: 278544434, states[0] = 14.455441, states[40]= 0.005136
Saving checkpoint... 
Iteration: 291002570, states[0] = 40.603341, states[40]= 0.122142
Saving checkpoint... 
Iteration: 302365717, states[0] = -94.886846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313465160, states[0] = -94.914992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325416234, states[0] = -94.904365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337769235, states[0] = -94.816562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349100808, states[0] = -18.832434, states[40]= 0.001068
Saving checkpoint... 
Iteration: 360104592, states[0] = -22.386362, states[40]= 0.000849
Saving checkpoint... 
Iteration: 373016041, states[0] = 22.620733, states[40]= 0.015564
Saving checkpoint... 
Iteration: 385176803, states[0] = -94.576047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399988201, states[0] = -94.918456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412148209, states[0] = -68.519038, states[40]= 0.000001
Saving checkpoint... 
Iteration: 423148634, states[0] = -69.091365, states[40]= 0.000001
Saving checkpoint... 
Iteration: 434427063, states[0] = -94.907078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445530701, states[0] = 19.168736, states[40]= 0.006009
Saving checkpoint... 
Iteration: 457250970, states[0] = -94.793640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468763183, states[0] = -94.809371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481092216, states[0] = -10.919709, states[40]= 0.002165
Saving checkpoint... 
Iteration: 493231052, states[0] = -94.763436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504621878, states[0] = -38.863035, states[40]= 0.000161
Saving checkpoint... 
Iteration: 515764874, states[0] = -94.811369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527828349, states[0] = -94.867023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539878575, states[0] = -94.891970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554053298, states[0] = 11.046349, states[40]= 0.004989
Saving checkpoint... 
Iteration: 565281942, states[0] = -94.829965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577483972, states[0] = -94.917749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589422308, states[0] = -94.905786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601717591, states[0] = -94.739508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613434929, states[0] = -94.908815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624762120, states[0] = -94.807975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636779156, states[0] = -94.827094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648754741, states[0] = -94.798583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662022250, states[0] = 21.420124, states[40]= 0.008188
Saving checkpoint... 
Iteration: 673741517, states[0] = -94.779910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684832845, states[0] = -94.869681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696393098, states[0] = -94.897113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711859242, states[0] = -94.883648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723282005, states[0] = -94.829924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735075293, states[0] = 1.031095, states[40]= 0.004413
Saving checkpoint... 
Iteration: 746634009, states[0] = -51.677913, states[40]= 0.000023
Saving checkpoint... 
Iteration: 757711484, states[0] = -94.727660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768861238, states[0] = -94.884530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780792902, states[0] = -94.840186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792984458, states[0] = -94.917677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803995631, states[0] = -94.919170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815163329, states[0] = -90.847601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826192619, states[0] = -94.687792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837989871, states[0] = -94.918395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852801882, states[0] = -94.847814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864009927, states[0] = 23.865383, states[40]= 0.053555
Saving checkpoint... 
Iteration: 875839842, states[0] = -94.873618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888003776, states[0] = 33.399993, states[40]= 0.155441
Saving checkpoint... 
Iteration: 899308658, states[0] = -94.853133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911385247, states[0] = -94.894226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924298799, states[0] = -94.845210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935657796, states[0] = -83.332672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947236972, states[0] = -94.772729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961021162, states[0] = 21.658598, states[40]= 0.008816
Saving checkpoint... 
Iteration: 973570672, states[0] = 3.438372, states[40]= 0.004648
Saving checkpoint... 
Iteration: 985416419, states[0] = -94.903977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997789484, states[0] = -94.836934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009268419, states[0] = -94.815185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021178991, states[0] = -94.618291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033543167, states[0] = 14.925456, states[40]= 0.005171
Saving checkpoint... 
Iteration: 1045868618, states[0] = -94.887599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057558495, states[0] = 8.934195, states[40]= 0.004930
Saving checkpoint... 
Iteration: 1068996641, states[0] = -94.919124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080389400, states[0] = -94.895593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092965720, states[0] = -94.914570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106578303, states[0] = -0.684891, states[40]= 0.004189
Saving checkpoint... 
Iteration: 1117770402, states[0] = -94.817365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130059115, states[0] = 8.675033, states[40]= 0.004922
Saving checkpoint... 
Iteration: 1141248959, states[0] = -94.790406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152577520, states[0] = -0.225251, states[40]= 0.004254
Saving checkpoint... 
Iteration: 1163863550, states[0] = -94.885314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175625419, states[0] = -42.444034, states[40]= 0.000095
Saving checkpoint... 
Iteration: 1190417131, states[0] = -94.904035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202412413, states[0] = -94.902731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214052225, states[0] = 11.470861, states[40]= 0.005002
Saving checkpoint... 
Iteration: 1225411933, states[0] = -94.902581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237372044, states[0] = -94.888907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249165922, states[0] = -92.707739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260546494, states[0] = 13.682126, states[40]= 0.005088
Saving checkpoint... 
Iteration: 1274577411, states[0] = -0.162004, states[40]= 0.004262
Saving checkpoint... 
Iteration: 1285956567, states[0] = -94.912821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298024241, states[0] = 20.951592, states[40]= 0.007356
Saving checkpoint... 
Iteration: 1310151923, states[0] = -73.789335, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1322203900, states[0] = -94.711964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333851114, states[0] = -94.879308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346001111, states[0] = 48.893270, states[40]= 0.036604
Saving checkpoint... 
Iteration: 1360066981, states[0] = 5.210527, states[40]= 0.004771
Saving checkpoint... 
Iteration: 1372968434, states[0] = -94.914841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384485319, states[0] = -94.917411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396238321, states[0] = -94.774543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409366737, states[0] = -94.886554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420241037, states[0] = -94.778693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434052633, states[0] = 11.309960, states[40]= 0.004997
Saving checkpoint... 
Iteration: 1445361594, states[0] = -94.884248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457469095, states[0] = -94.914895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469146930, states[0] = -66.835823, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1481674472, states[0] = -94.490325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499334102, states[0] = -94.869896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1510696597, states[0] = -95.034412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1522927445, states[0] = -68.025042, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1541248147, states[0] = -94.423740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1556378730, states[0] = -95.184306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1567815605, states[0] = 22.754544, states[40]= 0.018352
Saving checkpoint... 
Iteration: 1579758000, states[0] = -95.171625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1594665354, states[0] = -95.003399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1606098893, states[0] = -95.086750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1617134418, states[0] = -82.843786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628634854, states[0] = -95.148608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1640591775, states[0] = -95.073525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1653109377, states[0] = -47.268273, states[40]= 0.000048
Saving checkpoint... 
Iteration: 1664726354, states[0] = 19.150037, states[40]= 0.007871
Saving checkpoint... 
Iteration: 1679017193, states[0] = -95.122880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1692035170, states[0] = 15.434157, states[40]= 0.006506
Saving checkpoint... 
Iteration: 1703600369, states[0] = -95.092223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1715450881, states[0] = 7.603881, states[40]= 0.005630
Saving checkpoint... 
Iteration: 1726830006, states[0] = 17.684729, states[40]= 0.007129
Saving checkpoint... 
Iteration: 1738520840, states[0] = 21.106504, states[40]= 0.010358
Saving checkpoint... 
Iteration: 1753033046, states[0] = -80.563864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1766541446, states[0] = -92.356535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1778535072, states[0] = -84.175774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1790264541, states[0] = -95.004482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1804156934, states[0] = -88.627488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1816842621, states[0] = -94.919094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1829757721, states[0] = -94.833162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1840493471, states[0] = -94.941173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1852254524, states[0] = -94.813912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1863415019, states[0] = -94.914637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1874571618, states[0] = 2.763639, states[40]= 0.004598
Saving checkpoint... 
Iteration: 1885782355, states[0] = -94.835531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1898765105, states[0] = -94.814833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1912977222, states[0] = -94.918525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1925882825, states[0] = -94.894463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1936834594, states[0] = -94.871186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1949158913, states[0] = -85.246513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1961816117, states[0] = -94.858507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1978693068, states[0] = -94.688415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1990745575, states[0] = -94.785253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2002415545, states[0] = -94.903210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2014924556, states[0] = -94.905498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2027124009, states[0] = -41.007248, states[40]= 0.000118
Saving checkpoint... 
Iteration: 2042031970, states[0] = 18.777340, states[40]= 0.005860
Saving checkpoint... 
Iteration: 2053082209, states[0] = -3.141515, states[40]= 0.003783
Saving checkpoint... 
Iteration: 2066755597, states[0] = -94.798744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2078305230, states[0] = -94.849659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2089180253, states[0] = -94.633124, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.794693
 - CaMKt in component CaMK (millimolar): 0.007110
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.729123
 - nass in component intracellular_ions (millimolar): 6.729184
 - ki in component intracellular_ions (millimolar): 145.246177
 - kss in component intracellular_ions (millimolar): 145.246158
 - cansr in component intracellular_ions (millimolar): 1.321971
 - cajsr in component intracellular_ions (millimolar): 1.283738
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003658
 - hf in component INa (dimensionless): 0.878129
 - hs in component INa (dimensionless): 0.878124
 - j in component INa (dimensionless): 0.878093
 - hsp in component INa (dimensionless): 0.722311
 - jp in component INa (dimensionless): 0.878072
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.706760
 - hLp in component INaL (dimensionless): 0.447860
 - a in component Ito (dimensionless): 0.000628
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.618997
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.693041
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.932696
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999878
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001646
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.338387
 - xs1 in component IKs (dimensionless): 0.245640
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997365
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:10:42 (94136): called boinc_finish(0)

</stderr_txt>
]]>


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