𝕏

Task 55434265

Name HuVeMOp_20240630130118581586_ORdGradInc_k_25-Pueyo_APDR-conf_474_1
Workunit 26323455
Created 30 Jun 2024, 11:01:46 UTC
Sent 30 Jun 2024, 12:37:17 UTC
Report deadline 3 Jul 2024, 22:13:17 UTC
Received 1 Jul 2024, 14:46:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238614
Run time 2 hours 27 min 36 sec
CPU time 2 hours 27 min 19 sec
Validate state Valid
Credit 59.63
Device peak FLOPS 3.71 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.92 MB
Peak swap size 3.82 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>7.14.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630130118581586_ORdGradInc_k_25-Pueyo_APDR-conf_474.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630130118581586_ORdGradInc_k_25-Pueyo_APDR-conf_474_1_r502668855_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630130118581586_ORdGradInc_k_25-Pueyo_APDR-conf_474_1_r502668855_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 99.955752
     * GNaL_b in INaL: 0.007442
     * Gto_b in Ito: 0.080512
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032396
     * GKs_b in IKs: 0.001898
     * GK1_b in IK1: 0.176481
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 69.329217
     * GKb_b in IKb: 0.003702
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.021945
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12109569, states[0] = -28.251894, states[40]= 0.000557
Saving checkpoint... 
Iteration: 29351551, states[0] = -95.165003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43125003, states[0] = -40.726344, states[40]= 0.000130
Saving checkpoint... 
Iteration: 54863705, states[0] = -95.149385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66270795, states[0] = -95.082681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77832724, states[0] = -95.126335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94755725, states[0] = -95.059232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107276276, states[0] = -95.079772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118320966, states[0] = -95.113625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129630888, states[0] = -45.159579, states[40]= 0.000068
Saving checkpoint... 
Iteration: 143444804, states[0] = -95.157381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155010908, states[0] = 24.031899, states[40]= 0.042000
Saving checkpoint... 
Iteration: 166804992, states[0] = -95.100954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178930858, states[0] = -95.153690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195303308, states[0] = -95.099354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207189530, states[0] = -94.944136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218863999, states[0] = -95.132970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230871076, states[0] = -95.135729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243077114, states[0] = 1.465018, states[40]= 0.004457
Saving checkpoint... 
Iteration: 254381706, states[0] = -95.139547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265513725, states[0] = 23.530624, states[40]= 0.022869
Saving checkpoint... 
Iteration: 278769797, states[0] = -95.069665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292496248, states[0] = -95.164024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303344982, states[0] = -95.124246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314322885, states[0] = -95.112140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325615725, states[0] = -30.001312, states[40]= 0.000513
Saving checkpoint... 
Iteration: 338484823, states[0] = -95.162531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353055842, states[0] = 11.066574, states[40]= 0.004966
Saving checkpoint... 
Iteration: 368588754, states[0] = -5.880122, states[40]= 0.003230
Saving checkpoint... 
Iteration: 381416581, states[0] = -95.149759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395258278, states[0] = -95.056920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406663578, states[0] = -90.974679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418202483, states[0] = -94.970603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430331642, states[0] = -95.117158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443519989, states[0] = 22.531752, states[40]= 0.009477
Saving checkpoint... 
Iteration: 456535194, states[0] = 18.554601, states[40]= 0.005496
Saving checkpoint... 
Iteration: 468215027, states[0] = -94.993953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481986535, states[0] = -95.162657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494385788, states[0] = -95.140727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505558959, states[0] = 9.819369, states[40]= 0.004940
Saving checkpoint... 
Iteration: 518236155, states[0] = -95.027977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529709239, states[0] = -94.983403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541940370, states[0] = -95.155021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553501105, states[0] = 48.206411, states[40]= 0.038825
Saving checkpoint... 
Iteration: 564605318, states[0] = -20.337303, states[40]= 0.000978
Saving checkpoint... 
Iteration: 580370587, states[0] = -95.135209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592969031, states[0] = -95.160076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605171870, states[0] = -94.635072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619715024, states[0] = -94.993844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632860256, states[0] = -95.130992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645036187, states[0] = 18.232140, states[40]= 0.005429
Saving checkpoint... 
Iteration: 659338229, states[0] = -95.120566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672114890, states[0] = -29.218453, states[40]= 0.000552
Saving checkpoint... 
Iteration: 684699505, states[0] = -94.964543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696797872, states[0] = -95.094624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710954399, states[0] = -95.157566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723544461, states[0] = 15.367935, states[40]= 0.005099
Saving checkpoint... 
Iteration: 735150456, states[0] = -68.844504, states[40]= 0.000001
Saving checkpoint... 
Iteration: 748302935, states[0] = -95.098434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760577521, states[0] = 1.247600, states[40]= 0.004433
Saving checkpoint... 
Iteration: 772567476, states[0] = 6.185753, states[40]= 0.004817
Saving checkpoint... 
Iteration: 784131327, states[0] = -45.476781, states[40]= 0.000065
Saving checkpoint... 
Iteration: 795085227, states[0] = -3.384770, states[40]= 0.003734
Saving checkpoint... 
Iteration: 808113241, states[0] = -27.679007, states[40]= 0.000630
Saving checkpoint... 
Iteration: 825787860, states[0] = -95.086336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841453553, states[0] = -95.157326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854379890, states[0] = -95.138456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865543067, states[0] = 15.869121, states[40]= 0.005134
Saving checkpoint... 
Iteration: 880011268, states[0] = 23.958184, states[40]= 0.038664
Saving checkpoint... 
Iteration: 894503776, states[0] = 33.500477, states[40]= 0.160663
Saving checkpoint... 
Iteration: 906035308, states[0] = 18.517948, states[40]= 0.005488
Saving checkpoint... 
Iteration: 918720568, states[0] = -95.003231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931884833, states[0] = -95.140109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946065758, states[0] = 6.950560, states[40]= 0.004852
Saving checkpoint... 
Iteration: 958774067, states[0] = -95.073500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975355975, states[0] = -95.128904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987027697, states[0] = 20.776110, states[40]= 0.006358
Saving checkpoint... 
Iteration: 999167599, states[0] = -93.756576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010961279, states[0] = -95.158546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022967781, states[0] = -95.159589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034587711, states[0] = -5.113809, states[40]= 0.003391
Saving checkpoint... 
Iteration: 1045899797, states[0] = -95.144744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058512254, states[0] = 23.767582, states[40]= 0.031021
Saving checkpoint... 
Iteration: 1070155189, states[0] = -76.621486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081353872, states[0] = -95.127893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093052685, states[0] = 12.296077, states[40]= 0.004989
Saving checkpoint... 
Iteration: 1104952569, states[0] = -95.156971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116594681, states[0] = -10.667329, states[40]= 0.002210
Saving checkpoint... 
Iteration: 1127917348, states[0] = -95.149444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141716850, states[0] = -94.996698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153678708, states[0] = -94.895235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164833562, states[0] = -95.117721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176922980, states[0] = -95.150781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188938224, states[0] = -95.154145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204280563, states[0] = -95.079557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215351192, states[0] = -95.126577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226408134, states[0] = -95.146976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238112541, states[0] = -27.027221, states[40]= 0.000662
Saving checkpoint... 
Iteration: 1250076837, states[0] = 1.615992, states[40]= 0.004473
Saving checkpoint... 
Iteration: 1262750729, states[0] = -95.047198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278202598, states[0] = -94.970239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295521665, states[0] = 22.204158, states[40]= 0.008320
Saving checkpoint... 
Iteration: 1309185340, states[0] = -94.932417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320995791, states[0] = -95.163256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332126545, states[0] = -40.470519, states[40]= 0.000136
Saving checkpoint... 
Iteration: 1344390949, states[0] = -95.141834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355759021, states[0] = -95.057126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367638248, states[0] = -53.241270, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1381923076, states[0] = -95.150665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398607373, states[0] = -22.238246, states[40]= 0.000879
Saving checkpoint... 
Iteration: 1410640288, states[0] = -55.632877, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1423578821, states[0] = 0.531379, states[40]= 0.004348
Saving checkpoint... 
Iteration: 1437434786, states[0] = -95.153256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448785171, states[0] = -95.083565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460255579, states[0] = -95.053009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471312829, states[0] = -95.104919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482887733, states[0] = -95.140700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494642021, states[0] = -57.706608, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1506149784, states[0] = -94.592590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1517509126, states[0] = -41.347910, states[40]= 0.000119
Saving checkpoint... 
Iteration: 1528769244, states[0] = -95.366400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1540610472, states[0] = -44.317824, states[40]= 0.000079
Saving checkpoint... 
Iteration: 1552141021, states[0] = -95.351503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564681761, states[0] = -95.257443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581083453, states[0] = -15.857452, states[40]= 0.001541
Saving checkpoint... 
Iteration: 1592683414, states[0] = -95.400539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1605069927, states[0] = -3.177091, states[40]= 0.004276
Saving checkpoint... 
Iteration: 1616483617, states[0] = -16.224213, states[40]= 0.001490
Saving checkpoint... 
Iteration: 1628477960, states[0] = -10.398825, states[40]= 0.002577
Saving checkpoint... 
Iteration: 1641707325, states[0] = -41.906126, states[40]= 0.000112
Saving checkpoint... 
Iteration: 1656683582, states[0] = -16.252365, states[40]= 0.001486
Saving checkpoint... 
Iteration: 1669473879, states[0] = -95.396223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1681956566, states[0] = -95.188237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1694133611, states[0] = 16.891566, states[40]= 0.006603
Saving checkpoint... 
Iteration: 1709213481, states[0] = -49.372577, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1720338861, states[0] = -89.643275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1731180401, states[0] = -95.262809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1742462020, states[0] = 2.261162, states[40]= 0.005161
Saving checkpoint... 
Iteration: 1756440704, states[0] = -95.363741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1767694925, states[0] = -28.359456, states[40]= 0.000578
Saving checkpoint... 
Iteration: 1778776419, states[0] = -8.943769, states[40]= 0.002920
Saving checkpoint... 
Iteration: 1790438924, states[0] = 14.505814, states[40]= 0.006191
Saving checkpoint... 
Iteration: 1802622484, states[0] = -40.886028, states[40]= 0.000143
Saving checkpoint... 
Iteration: 1819178272, states[0] = -94.940197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1835587966, states[0] = -6.385615, states[40]= 0.003147
Saving checkpoint... 
Iteration: 1849744735, states[0] = -95.053578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1863814760, states[0] = -95.115432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1878001294, states[0] = 48.457321, states[40]= 0.053754
Saving checkpoint... 
Iteration: 1892059838, states[0] = 9.364460, states[40]= 0.004934
Saving checkpoint... 
Iteration: 1904340808, states[0] = -95.123893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1920725213, states[0] = -95.011985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1935710145, states[0] = -94.985232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1947322697, states[0] = -95.111671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1958595933, states[0] = -11.795255, states[40]= 0.001994
Saving checkpoint... 
Iteration: 1971638231, states[0] = -53.259536, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1987348308, states[0] = -95.124892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2001173427, states[0] = -94.750588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2013474593, states[0] = -95.160009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028418800, states[0] = -95.149206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2040195409, states[0] = -94.955312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050987126, states[0] = -95.161646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2062224556, states[0] = -95.009024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2073885094, states[0] = -95.139378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2086063418, states[0] = 7.964154, states[40]= 0.004890
Saving checkpoint... 
Iteration: 2099848146, states[0] = -95.124490, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.039047
 - CaMKt in component CaMK (millimolar): 0.007282
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.597544
 - nass in component intracellular_ions (millimolar): 6.597606
 - ki in component intracellular_ions (millimolar): 145.375574
 - kss in component intracellular_ions (millimolar): 145.375554
 - cansr in component intracellular_ions (millimolar): 1.330631
 - cajsr in component intracellular_ions (millimolar): 1.291871
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003569
 - hf in component INa (dimensionless): 0.882361
 - hs in component INa (dimensionless): 0.882356
 - j in component INa (dimensionless): 0.882328
 - hsp in component INa (dimensionless): 0.730293
 - jp in component INa (dimensionless): 0.882309
 - mL in component INaL (dimensionless): 0.000048
 - hL in component INaL (dimensionless): 0.712861
 - hLp in component INaL (dimensionless): 0.454192
 - a in component Ito (dimensionless): 0.000618
 - iF in component Ito (dimensionless): 0.999873
 - iS in component Ito (dimensionless): 0.618006
 - ap in component Ito (dimensionless): 0.000315
 - iFp in component Ito (dimensionless): 0.999873
 - iSp in component Ito (dimensionless): 0.692068
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.929042
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999867
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001682
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.338675
 - xs1 in component IKs (dimensionless): 0.252497
 - xs2 in component IKs (dimensionless): 0.000086
 - xk1 in component IK1 (dimensionless): 0.997301
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:46:06 (94196): called boinc_finish(0)

</stderr_txt>
]]>


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