𝕏

Task 55433953

Name HuVeMOp_20240630130118581586_ORdGradInc_k_25-Pueyo_APDR-conf_130_1
Workunit 26323299
Created 30 Jun 2024, 11:01:36 UTC
Sent 30 Jun 2024, 12:37:17 UTC
Report deadline 3 Jul 2024, 22:13:17 UTC
Received 1 Jul 2024, 12:32:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238614
Run time 2 hours 40 min 41 sec
CPU time 2 hours 40 min 10 sec
Validate state Valid
Credit 59.29
Device peak FLOPS 3.71 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.93 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.14.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630130118581586_ORdGradInc_k_25-Pueyo_APDR-conf_130.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630130118581586_ORdGradInc_k_25-Pueyo_APDR-conf_130_1_r938733991_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630130118581586_ORdGradInc_k_25-Pueyo_APDR-conf_130_1_r938733991_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 107.508361
     * GNaL_b in INaL: 0.005338
     * Gto_b in Ito: 0.070930
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031706
     * GKs_b in IKs: 0.001995
     * GK1_b in IK1: 0.149270
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 66.252085
     * GKb_b in IKb: 0.003812
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.027487
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12315454, states[0] = -95.008303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23998089, states[0] = -95.039119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35995266, states[0] = -95.021798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48343474, states[0] = -94.967290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60503411, states[0] = 37.073239, states[40]= 0.135159
Saving checkpoint... 
Iteration: 72943128, states[0] = -94.988933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85504085, states[0] = 34.031419, states[40]= 0.141806
Saving checkpoint... 
Iteration: 97706859, states[0] = -94.793211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110114793, states[0] = -37.622037, states[40]= 0.000178
Saving checkpoint... 
Iteration: 122166192, states[0] = -94.162720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133601482, states[0] = -24.374176, states[40]= 0.000729
Saving checkpoint... 
Iteration: 145059557, states[0] = 6.874578, states[40]= 0.005026
Saving checkpoint... 
Iteration: 156588179, states[0] = -11.430480, states[40]= 0.002115
Saving checkpoint... 
Iteration: 168642886, states[0] = -68.189063, states[40]= 0.000001
Saving checkpoint... 
Iteration: 181037782, states[0] = 16.067557, states[40]= 0.005790
Saving checkpoint... 
Iteration: 193094721, states[0] = -17.653424, states[40]= 0.001184
Saving checkpoint... 
Iteration: 205042318, states[0] = 14.275035, states[40]= 0.005519
Saving checkpoint... 
Iteration: 217241880, states[0] = -94.848349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229322840, states[0] = -94.929783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240813358, states[0] = -94.923235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251389685, states[0] = -94.961974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261834139, states[0] = -94.936673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272988351, states[0] = -94.984272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284179880, states[0] = -94.716822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295604271, states[0] = -26.986789, states[40]= 0.000603
Saving checkpoint... 
Iteration: 310360770, states[0] = -94.950376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323071043, states[0] = 1.138035, states[40]= 0.004540
Saving checkpoint... 
Iteration: 334626759, states[0] = -49.802976, states[40]= 0.000028
Saving checkpoint... 
Iteration: 346264373, states[0] = -94.877724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358508128, states[0] = 26.183500, states[40]= 0.079941
Saving checkpoint... 
Iteration: 370876343, states[0] = -94.956909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382529868, states[0] = 18.984592, states[40]= 0.006680
Saving checkpoint... 
Iteration: 395267313, states[0] = -94.881092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408051722, states[0] = 10.371002, states[40]= 0.005210
Saving checkpoint... 
Iteration: 419677887, states[0] = -94.703424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431269145, states[0] = -94.883138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443186949, states[0] = -94.742452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454915958, states[0] = -94.969848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467155733, states[0] = -87.132699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479946837, states[0] = -94.977113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491694942, states[0] = -94.761449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503822201, states[0] = -94.929059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515921072, states[0] = -94.971168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528130269, states[0] = -53.602297, states[40]= 0.000015
Saving checkpoint... 
Iteration: 539198352, states[0] = -94.768888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550804917, states[0] = -94.916635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563050023, states[0] = 11.094176, states[40]= 0.005252
Saving checkpoint... 
Iteration: 574662795, states[0] = -93.234096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586897205, states[0] = -94.964220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599884366, states[0] = -94.959811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611259891, states[0] = -94.872189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622775182, states[0] = -94.889577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634190403, states[0] = -94.750979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647995181, states[0] = -94.984930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658440975, states[0] = -94.975788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668869809, states[0] = -94.954097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679961760, states[0] = -94.979837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694475592, states[0] = -94.982126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705864737, states[0] = -94.951910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717551283, states[0] = 10.558731, states[40]= 0.005221
Saving checkpoint... 
Iteration: 728648894, states[0] = -76.501414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741312960, states[0] = -94.922561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752384491, states[0] = -94.959772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763620769, states[0] = -43.457431, states[40]= 0.000075
Saving checkpoint... 
Iteration: 774200256, states[0] = -94.772839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785076431, states[0] = -2.108781, states[40]= 0.004060
Saving checkpoint... 
Iteration: 795819494, states[0] = -94.927091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806025947, states[0] = 20.282225, states[40]= 0.007543
Saving checkpoint... 
Iteration: 815850055, states[0] = -94.944955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825863814, states[0] = -94.951437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837120994, states[0] = -43.691467, states[40]= 0.000073
Saving checkpoint... 
Iteration: 847039462, states[0] = 15.418725, states[40]= 0.005676
Saving checkpoint... 
Iteration: 856849915, states[0] = -94.944862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868170971, states[0] = -94.560771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878733739, states[0] = -94.835265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889949789, states[0] = -94.977478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901873564, states[0] = -94.955507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912284808, states[0] = -94.899060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923034168, states[0] = 17.445366, states[40]= 0.006108
Saving checkpoint... 
Iteration: 934619098, states[0] = -41.730446, states[40]= 0.000098
Saving checkpoint... 
Iteration: 945644882, states[0] = -70.732950, states[40]= 0.000001
Saving checkpoint... 
Iteration: 957110127, states[0] = -32.738555, states[40]= 0.000338
Saving checkpoint... 
Iteration: 967841317, states[0] = -94.940285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978852086, states[0] = -94.945876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989920171, states[0] = -94.970671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001512157, states[0] = 24.150027, states[40]= 0.033392
Saving checkpoint... 
Iteration: 1013247558, states[0] = -94.855824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025041126, states[0] = 14.758213, states[40]= 0.005579
Saving checkpoint... 
Iteration: 1037259100, states[0] = -94.870976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049508686, states[0] = 25.759263, states[40]= 0.070816
Saving checkpoint... 
Iteration: 1060998220, states[0] = -94.985087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072932578, states[0] = -94.973681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085103060, states[0] = -25.798620, states[40]= 0.000660
Saving checkpoint... 
Iteration: 1096898297, states[0] = -94.964288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106646042, states[0] = -72.325960, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1116614990, states[0] = -37.565782, states[40]= 0.000179
Saving checkpoint... 
Iteration: 1126910728, states[0] = -94.968022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138751452, states[0] = -94.861070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149929551, states[0] = -94.972925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161201104, states[0] = -94.774422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172816833, states[0] = -94.925059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183138739, states[0] = -63.074642, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1195000945, states[0] = 48.263899, states[40]= 0.022143
Saving checkpoint... 
Iteration: 1206720201, states[0] = -94.811988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217903264, states[0] = -94.965772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230464574, states[0] = -94.980024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243238168, states[0] = -94.841986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255640252, states[0] = -64.864703, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1266880109, states[0] = -94.957860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278133520, states[0] = -57.167489, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1288436942, states[0] = -94.974555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298851465, states[0] = -94.945391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308844840, states[0] = -94.941991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319240785, states[0] = -94.845895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329755468, states[0] = -94.866231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339728713, states[0] = -94.826778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350132895, states[0] = -56.477531, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1361563393, states[0] = 5.099190, states[40]= 0.004913
Saving checkpoint... 
Iteration: 1373009058, states[0] = 25.514241, states[40]= 0.065249
Saving checkpoint... 
Iteration: 1384762778, states[0] = -94.875252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395758324, states[0] = -94.869811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406060481, states[0] = 6.478442, states[40]= 0.005002
Saving checkpoint... 
Iteration: 1417870730, states[0] = -94.954064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429269715, states[0] = -94.883217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440773732, states[0] = -94.887585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451393293, states[0] = -94.962454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462054464, states[0] = 9.185299, states[40]= 0.005147
Saving checkpoint... 
Iteration: 1473085436, states[0] = -8.922924, states[40]= 0.002637
Saving checkpoint... 
Iteration: 1484489398, states[0] = -94.983699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495727723, states[0] = -94.825023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506091423, states[0] = -27.878778, states[40]= 0.000541
Saving checkpoint... 
Iteration: 1516722932, states[0] = -95.165972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1527584467, states[0] = -95.246974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1539366627, states[0] = -3.730049, states[40]= 0.004185
Saving checkpoint... 
Iteration: 1551034117, states[0] = 15.597940, states[40]= 0.007012
Saving checkpoint... 
Iteration: 1562402994, states[0] = 40.515055, states[40]= 0.096550
Saving checkpoint... 
Iteration: 1573902300, states[0] = -43.125822, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1585339327, states[0] = -92.657350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1596147794, states[0] = -94.833877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1607626364, states[0] = -95.214635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1618711244, states[0] = -95.191093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1629872813, states[0] = -95.270135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1641067561, states[0] = -5.273597, states[40]= 0.003848
Saving checkpoint... 
Iteration: 1652865139, states[0] = -95.087867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1663635802, states[0] = -89.782012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1675081074, states[0] = -95.130445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686283663, states[0] = -95.280493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1697504785, states[0] = -46.516067, states[40]= 0.000049
Saving checkpoint... 
Iteration: 1709018901, states[0] = -95.205877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1720049882, states[0] = -94.944451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1730489721, states[0] = -29.288789, states[40]= 0.000488
Saving checkpoint... 
Iteration: 1741716431, states[0] = -95.201902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1753096532, states[0] = -95.165137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1764773098, states[0] = -95.110738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1775521952, states[0] = -68.132578, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1786634031, states[0] = -87.473434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1797900815, states[0] = 45.737868, states[40]= 0.010620
Saving checkpoint... 
Iteration: 1809738853, states[0] = -94.895870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1821262088, states[0] = -94.915901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833654244, states[0] = -87.912798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1845860478, states[0] = -94.970525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1857925757, states[0] = -94.986580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1870254948, states[0] = -94.875974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1882242635, states[0] = -94.855951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1894625641, states[0] = -48.950998, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1906416838, states[0] = -94.973035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1918089689, states[0] = -12.914002, states[40]= 0.001841
Saving checkpoint... 
Iteration: 1929659606, states[0] = -91.498171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1942231647, states[0] = -94.832666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1954754229, states[0] = -94.865225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1966654096, states[0] = -84.800357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1978600347, states[0] = -23.168280, states[40]= 0.000790
Saving checkpoint... 
Iteration: 1990976165, states[0] = -94.981801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2003708712, states[0] = -94.789816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2015931162, states[0] = -94.972954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028337868, states[0] = -94.937855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2040293755, states[0] = -94.906637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2052050924, states[0] = 10.711026, states[40]= 0.005230
Saving checkpoint... 
Iteration: 2063795801, states[0] = -94.908347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2076137989, states[0] = -62.205119, states[40]= 0.000003
Saving checkpoint... 
Iteration: 2088211271, states[0] = -94.794609, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.860578
 - CaMKt in component CaMK (millimolar): 0.006728
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.639282
 - nass in component intracellular_ions (millimolar): 6.639341
 - ki in component intracellular_ions (millimolar): 145.340689
 - kss in component intracellular_ions (millimolar): 145.340670
 - cansr in component intracellular_ions (millimolar): 1.304931
 - cajsr in component intracellular_ions (millimolar): 1.267743
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003634
 - hf in component INa (dimensionless): 0.879283
 - hs in component INa (dimensionless): 0.879278
 - j in component INa (dimensionless): 0.879247
 - hsp in component INa (dimensionless): 0.724477
 - jp in component INa (dimensionless): 0.879226
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709520
 - hLp in component INaL (dimensionless): 0.452819
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.624862
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.699991
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936408
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999891
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001590
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.338433
 - xs1 in component IKs (dimensionless): 0.235252
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997348
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
14:31:55 (94040): called boinc_finish(0)

</stderr_txt>
]]>


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