𝕏

Task 55433757

Name HuVeMOp_20240630130118581586_ORdGradInc_k_25-Pueyo_APDR-conf_713_1
Workunit 26323201
Created 30 Jun 2024, 11:01:26 UTC
Sent 30 Jun 2024, 12:37:17 UTC
Report deadline 3 Jul 2024, 22:13:17 UTC
Received 1 Jul 2024, 14:46:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238614
Run time 2 hours 30 min 36 sec
CPU time 2 hours 30 min
Validate state Valid
Credit 59.10
Device peak FLOPS 3.71 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.93 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.14.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630130118581586_ORdGradInc_k_25-Pueyo_APDR-conf_713.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630130118581586_ORdGradInc_k_25-Pueyo_APDR-conf_713_1_r1573727461_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630130118581586_ORdGradInc_k_25-Pueyo_APDR-conf_713_1_r1573727461_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 112.618787
     * GNaL_b in INaL: 0.007354
     * Gto_b in Ito: 0.082741
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032275
     * GKs_b in IKs: 0.001816
     * GK1_b in IK1: 0.173519
     * Gncx_b in INaCa_i: 0.000956
     * Pnak_b in INaK: 67.037551
     * GKb_b in IKb: 0.003872
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035313
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12581974, states[0] = -4.248556, states[40]= 0.003553
Saving checkpoint... 
Iteration: 23803382, states[0] = -94.962307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35505486, states[0] = 27.962601, states[40]= 0.144219
Saving checkpoint... 
Iteration: 47207907, states[0] = -94.831782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58147193, states[0] = -67.310623, states[40]= 0.000002
Saving checkpoint... 
Iteration: 69189311, states[0] = -94.788890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80297136, states[0] = -94.932803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92826999, states[0] = -94.950858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107748362, states[0] = -94.882123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118758363, states[0] = -94.893386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131454422, states[0] = -94.989955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143286179, states[0] = -94.919855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155210665, states[0] = -94.823588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166411759, states[0] = -94.980451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177673263, states[0] = -94.618804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190096914, states[0] = -14.855742, states[40]= 0.001506
Saving checkpoint... 
Iteration: 201656468, states[0] = -81.199885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212874841, states[0] = -94.969084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225269558, states[0] = -94.903742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236612480, states[0] = -29.131375, states[40]= 0.000550
Saving checkpoint... 
Iteration: 248840072, states[0] = -94.954358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260351987, states[0] = -94.959918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272318065, states[0] = -94.942149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284027982, states[0] = 19.861228, states[40]= 0.006432
Saving checkpoint... 
Iteration: 296286906, states[0] = -94.919617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309820666, states[0] = -94.943693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320554265, states[0] = 10.616016, states[40]= 0.005003
Saving checkpoint... 
Iteration: 332561385, states[0] = 7.685842, states[40]= 0.004913
Saving checkpoint... 
Iteration: 347330323, states[0] = -94.949189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358949475, states[0] = -94.987892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370568270, states[0] = 4.603377, states[40]= 0.004757
Saving checkpoint... 
Iteration: 382691345, states[0] = -94.786148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394180317, states[0] = -94.752024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408114741, states[0] = -31.221251, states[40]= 0.000446
Saving checkpoint... 
Iteration: 420233095, states[0] = -94.859117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432151037, states[0] = -71.833122, states[40]= 0.000001
Saving checkpoint... 
Iteration: 443858968, states[0] = -94.962751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455933322, states[0] = -94.984762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467711033, states[0] = -94.823490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481151338, states[0] = -72.302641, states[40]= 0.000001
Saving checkpoint... 
Iteration: 495959825, states[0] = -94.989529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511956257, states[0] = -94.988941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524388004, states[0] = -94.973166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535539888, states[0] = 16.033978, states[40]= 0.005316
Saving checkpoint... 
Iteration: 547597798, states[0] = -15.649744, states[40]= 0.001401
Saving checkpoint... 
Iteration: 559176540, states[0] = -94.712420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570077926, states[0] = -0.410123, states[40]= 0.004249
Saving checkpoint... 
Iteration: 581714301, states[0] = -94.829124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593258210, states[0] = -94.891321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605623527, states[0] = -39.577708, states[40]= 0.000151
Saving checkpoint... 
Iteration: 618654911, states[0] = -78.331759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633701567, states[0] = -94.806036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646708059, states[0] = -94.818043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658011798, states[0] = 23.295540, states[40]= 0.035391
Saving checkpoint... 
Iteration: 669459484, states[0] = -94.989358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682522827, states[0] = 21.182265, states[40]= 0.007915
Saving checkpoint... 
Iteration: 694160479, states[0] = -88.150188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705224658, states[0] = -94.846139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721228952, states[0] = -94.852762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733801927, states[0] = -94.931043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746493330, states[0] = -94.993926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759215248, states[0] = -94.830630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770396111, states[0] = -94.975443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783396624, states[0] = -94.975583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795988396, states[0] = -94.993309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808566668, states[0] = 5.348609, states[40]= 0.004803
Saving checkpoint... 
Iteration: 821953881, states[0] = -94.988335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834123865, states[0] = -39.911166, states[40]= 0.000144
Saving checkpoint... 
Iteration: 850751355, states[0] = -94.883123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863431386, states[0] = -94.984087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875560167, states[0] = 8.202889, states[40]= 0.004932
Saving checkpoint... 
Iteration: 889433692, states[0] = -94.984544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900658816, states[0] = -85.443924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915352257, states[0] = -94.959569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927107569, states[0] = -24.613832, states[40]= 0.000769
Saving checkpoint... 
Iteration: 938651227, states[0] = -72.128020, states[40]= 0.000001
Saving checkpoint... 
Iteration: 950216228, states[0] = -94.832171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961575589, states[0] = 0.904237, states[40]= 0.004420
Saving checkpoint... 
Iteration: 974016085, states[0] = 22.517130, states[40]= 0.015551
Saving checkpoint... 
Iteration: 986140701, states[0] = -58.179729, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1001066412, states[0] = 5.465988, states[40]= 0.004810
Saving checkpoint... 
Iteration: 1012917170, states[0] = -94.980820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025221001, states[0] = -94.840060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040485888, states[0] = -94.992836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055576808, states[0] = 0.228504, states[40]= 0.004335
Saving checkpoint... 
Iteration: 1070160057, states[0] = -87.503792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082124616, states[0] = -40.656739, states[40]= 0.000129
Saving checkpoint... 
Iteration: 1093376161, states[0] = -94.968857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105385966, states[0] = -94.972129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121772516, states[0] = -94.905995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135503041, states[0] = 37.858742, states[40]= 0.142005
Saving checkpoint... 
Iteration: 1149457495, states[0] = -94.988712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160422724, states[0] = -94.982007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172093826, states[0] = -12.073967, states[40]= 0.001954
Saving checkpoint... 
Iteration: 1183192770, states[0] = -94.788519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194097855, states[0] = -15.701458, states[40]= 0.001395
Saving checkpoint... 
Iteration: 1207920694, states[0] = -94.981512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220318173, states[0] = -94.941556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232597438, states[0] = -15.320934, states[40]= 0.001443
Saving checkpoint... 
Iteration: 1244232127, states[0] = -94.857141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255749019, states[0] = -94.879982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270208210, states[0] = -94.817891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281515342, states[0] = 22.643367, states[40]= 0.017539
Saving checkpoint... 
Iteration: 1294890388, states[0] = -94.973383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307321022, states[0] = -94.943224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318419582, states[0] = -94.981180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329845037, states[0] = -94.955994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342793990, states[0] = -94.924653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354264361, states[0] = -94.897539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365849239, states[0] = -94.957915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380322283, states[0] = -94.943924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393777842, states[0] = -94.910867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406173381, states[0] = -94.621969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423304881, states[0] = -94.932680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434907158, states[0] = -94.978037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446274239, states[0] = -94.907441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457724456, states[0] = -94.845308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468983581, states[0] = -94.992257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482216620, states[0] = -94.832473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493789816, states[0] = -94.921210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1507776791, states[0] = -95.194259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1521987400, states[0] = -20.472242, states[40]= 0.001029
Saving checkpoint... 
Iteration: 1533382295, states[0] = -15.663143, states[40]= 0.001565
Saving checkpoint... 
Iteration: 1545886328, states[0] = -95.231784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1557022958, states[0] = 20.456998, states[40]= 0.009126
Saving checkpoint... 
Iteration: 1568277046, states[0] = -95.093476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579592070, states[0] = -26.977623, states[40]= 0.000643
Saving checkpoint... 
Iteration: 1591438540, states[0] = -95.200375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1602355164, states[0] = 5.294499, states[40]= 0.005482
Saving checkpoint... 
Iteration: 1614400254, states[0] = -35.878842, states[40]= 0.000250
Saving checkpoint... 
Iteration: 1625367778, states[0] = -95.231959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636845356, states[0] = 10.513270, states[40]= 0.005903
Saving checkpoint... 
Iteration: 1648867205, states[0] = -2.592769, states[40]= 0.004407
Saving checkpoint... 
Iteration: 1662616331, states[0] = 22.434674, states[40]= 0.016577
Saving checkpoint... 
Iteration: 1675854154, states[0] = 5.817262, states[40]= 0.005529
Saving checkpoint... 
Iteration: 1688044326, states[0] = -95.210308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1702790339, states[0] = -95.249925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1715795315, states[0] = -30.703368, states[40]= 0.000458
Saving checkpoint... 
Iteration: 1732087982, states[0] = -95.124551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1743968172, states[0] = -3.362090, states[40]= 0.004248
Saving checkpoint... 
Iteration: 1756178662, states[0] = -95.241704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1767430397, states[0] = -75.535484, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1781693695, states[0] = -95.252131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1793257496, states[0] = -95.044175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1805760081, states[0] = -94.937429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1818194992, states[0] = -94.826467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1830955074, states[0] = -95.013183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1843479300, states[0] = -95.008992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856172411, states[0] = -94.633222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1869551446, states[0] = 11.570188, states[40]= 0.005039
Saving checkpoint... 
Iteration: 1883725567, states[0] = -94.852143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1896620411, states[0] = -36.804633, states[40]= 0.000223
Saving checkpoint... 
Iteration: 1908335473, states[0] = -94.953385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1922641553, states[0] = -59.345857, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1936684117, states[0] = -94.768713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1947929390, states[0] = -94.983670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1959431670, states[0] = -94.983911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1971356804, states[0] = -94.961153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1984845675, states[0] = -94.956059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1997632445, states[0] = -48.852971, states[40]= 0.000037
Saving checkpoint... 
Iteration: 2009272395, states[0] = -94.905345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2019995561, states[0] = -94.993353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2031068712, states[0] = 4.392982, states[40]= 0.004743
Saving checkpoint... 
Iteration: 2045343913, states[0] = -94.954959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2058782117, states[0] = -94.914248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2073131986, states[0] = -48.339700, states[40]= 0.000041
Saving checkpoint... 
Iteration: 2085737399, states[0] = -94.864067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098452666, states[0] = -94.987213, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.869580
 - CaMKt in component CaMK (millimolar): 0.007267
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.753351
 - nass in component intracellular_ions (millimolar): 6.753412
 - ki in component intracellular_ions (millimolar): 145.219547
 - kss in component intracellular_ions (millimolar): 145.219527
 - cansr in component intracellular_ions (millimolar): 1.332166
 - cajsr in component intracellular_ions (millimolar): 1.293769
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003630
 - hf in component INa (dimensionless): 0.879440
 - hs in component INa (dimensionless): 0.879435
 - j in component INa (dimensionless): 0.879408
 - hsp in component INa (dimensionless): 0.724776
 - jp in component INa (dimensionless): 0.879390
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708820
 - hLp in component INaL (dimensionless): 0.450339
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.618955
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.693261
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.932584
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999876
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001687
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.339774
 - xs1 in component IKs (dimensionless): 0.246116
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997346
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:05:12 (94216): called boinc_finish(0)

</stderr_txt>
]]>


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