𝕏

Task 55433437

Name HuVeMOp_20240630130042325463_ORdGradInc_k_25-Pueyo_APDR-conf_464_0
Workunit 26323042
Created 30 Jun 2024, 11:01:15 UTC
Sent 30 Jun 2024, 12:37:17 UTC
Report deadline 3 Jul 2024, 22:13:17 UTC
Received 1 Jul 2024, 13:33:31 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238614
Run time 2 hours 38 min 33 sec
CPU time 2 hours 38 min 8 sec
Validate state Valid
Credit 60.27
Device peak FLOPS 3.71 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.93 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.14.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630130042325463_ORdGradInc_k_25-Pueyo_APDR-conf_464.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630130042325463_ORdGradInc_k_25-Pueyo_APDR-conf_464_0_r530265815_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630130042325463_ORdGradInc_k_25-Pueyo_APDR-conf_464_0_r530265815_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.670300
     * GNaL_b in INaL: 0.005762
     * Gto_b in Ito: 0.076972
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033466
     * GKs_b in IKs: 0.002047
     * GK1_b in IK1: 0.152641
     * Gncx_b in INaCa_i: 0.000972
     * Pnak_b in INaK: 68.073509
     * GKb_b in IKb: 0.003703
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035424
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12146465, states[0] = -82.759733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24423243, states[0] = -94.928261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36478496, states[0] = -94.922635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48270403, states[0] = -94.820005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60866513, states[0] = -94.877373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71852290, states[0] = -94.866822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82963500, states[0] = -94.895622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93347559, states[0] = -94.859259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104086049, states[0] = -10.329409, states[40]= 0.002312
Saving checkpoint... 
Iteration: 115419008, states[0] = -94.881644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127312453, states[0] = -94.835043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139532208, states[0] = 17.725300, states[40]= 0.006127
Saving checkpoint... 
Iteration: 150551539, states[0] = 10.127737, states[40]= 0.005086
Saving checkpoint... 
Iteration: 164151707, states[0] = -84.098577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176473452, states[0] = -94.889522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187164970, states[0] = -94.183863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200690738, states[0] = -94.670452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214283609, states[0] = -94.809925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225455920, states[0] = -94.886280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236334120, states[0] = -94.846272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247385557, states[0] = -94.868777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258061809, states[0] = 5.553645, states[40]= 0.004855
Saving checkpoint... 
Iteration: 271228691, states[0] = -94.742023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284430362, states[0] = -94.881100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295593254, states[0] = -17.048247, states[40]= 0.001229
Saving checkpoint... 
Iteration: 306153625, states[0] = -86.918760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319586202, states[0] = -10.275397, states[40]= 0.002321
Saving checkpoint... 
Iteration: 334404513, states[0] = -94.874551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347590252, states[0] = -14.098130, states[40]= 0.001622
Saving checkpoint... 
Iteration: 361458582, states[0] = -94.886537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372635967, states[0] = -61.795391, states[40]= 0.000003
Saving checkpoint... 
Iteration: 383505701, states[0] = 28.057643, states[40]= 0.127445
Saving checkpoint... 
Iteration: 394230793, states[0] = -94.745258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404840624, states[0] = -94.849588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415532804, states[0] = 17.533609, states[40]= 0.006057
Saving checkpoint... 
Iteration: 425671032, states[0] = -94.553328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436798027, states[0] = -94.821962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448080490, states[0] = -5.461685, states[40]= 0.003358
Saving checkpoint... 
Iteration: 459039305, states[0] = 15.121457, states[40]= 0.005514
Saving checkpoint... 
Iteration: 469603582, states[0] = -27.320477, states[40]= 0.000564
Saving checkpoint... 
Iteration: 480146110, states[0] = -75.098045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491179487, states[0] = -94.639888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501760715, states[0] = -94.785855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513092988, states[0] = -16.783911, states[40]= 0.001259
Saving checkpoint... 
Iteration: 524624660, states[0] = -49.064137, states[40]= 0.000030
Saving checkpoint... 
Iteration: 535607432, states[0] = -31.158343, states[40]= 0.000389
Saving checkpoint... 
Iteration: 546950356, states[0] = -94.884974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558345685, states[0] = -94.852077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569826957, states[0] = -94.841864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580901383, states[0] = -94.873505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591616433, states[0] = -40.272978, states[40]= 0.000117
Saving checkpoint... 
Iteration: 603144903, states[0] = -73.308955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614137610, states[0] = -63.745810, states[40]= 0.000002
Saving checkpoint... 
Iteration: 625485595, states[0] = -94.890427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637383841, states[0] = -94.867901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649601004, states[0] = -24.755551, states[40]= 0.000687
Saving checkpoint... 
Iteration: 661973278, states[0] = -94.888693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674182801, states[0] = -94.650807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686101641, states[0] = -25.389105, states[40]= 0.000656
Saving checkpoint... 
Iteration: 696100349, states[0] = -24.104070, states[40]= 0.000719
Saving checkpoint... 
Iteration: 708142432, states[0] = -69.853545, states[40]= 0.000001
Saving checkpoint... 
Iteration: 720333724, states[0] = -94.845683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732315982, states[0] = -94.834859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743795778, states[0] = -94.819977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755756772, states[0] = -94.781031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768040041, states[0] = 14.835612, states[40]= 0.005472
Saving checkpoint... 
Iteration: 780568043, states[0] = 2.432369, states[40]= 0.004611
Saving checkpoint... 
Iteration: 792574515, states[0] = -1.299076, states[40]= 0.004138
Saving checkpoint... 
Iteration: 804307758, states[0] = -94.829123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816530631, states[0] = 18.284595, states[40]= 0.006338
Saving checkpoint... 
Iteration: 828521002, states[0] = 21.158167, states[40]= 0.009523
Saving checkpoint... 
Iteration: 840505468, states[0] = 28.542103, states[40]= 0.131538
Saving checkpoint... 
Iteration: 852791958, states[0] = -94.816748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864414597, states[0] = -94.876971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877221294, states[0] = -94.729350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889484905, states[0] = -94.890187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901046113, states[0] = 12.406851, states[40]= 0.005221
Saving checkpoint... 
Iteration: 912283739, states[0] = -94.809468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923892530, states[0] = -94.870613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934853109, states[0] = -94.855422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946259914, states[0] = -94.784665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957113656, states[0] = -37.421468, states[40]= 0.000175
Saving checkpoint... 
Iteration: 968346706, states[0] = -94.852348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979486639, states[0] = -94.890362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990896339, states[0] = -94.871763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001180398, states[0] = -94.643023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012521690, states[0] = 20.980302, states[40]= 0.009064
Saving checkpoint... 
Iteration: 1024308690, states[0] = -94.829667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035140725, states[0] = -67.609658, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1046013465, states[0] = 22.914312, states[40]= 0.025421
Saving checkpoint... 
Iteration: 1057397033, states[0] = -94.871937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069028305, states[0] = 19.050671, states[40]= 0.006733
Saving checkpoint... 
Iteration: 1080480677, states[0] = -94.889509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091450084, states[0] = -94.884614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102285075, states[0] = -94.810579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113968383, states[0] = -94.887696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128662858, states[0] = -93.816038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139579783, states[0] = -4.923616, states[40]= 0.003470
Saving checkpoint... 
Iteration: 1150027423, states[0] = 19.330038, states[40]= 0.006917
Saving checkpoint... 
Iteration: 1160910157, states[0] = -94.875634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172175164, states[0] = -94.614190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183614736, states[0] = -38.524290, states[40]= 0.000150
Saving checkpoint... 
Iteration: 1194767847, states[0] = -94.793455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205822734, states[0] = -94.838930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217140670, states[0] = -67.538847, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1228335314, states[0] = -94.846274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239661073, states[0] = -93.300722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250695324, states[0] = -94.679393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262194859, states[0] = -94.678408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273330040, states[0] = -94.843274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284609858, states[0] = -33.585998, states[40]= 0.000292
Saving checkpoint... 
Iteration: 1296651461, states[0] = -83.627197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307485605, states[0] = -94.890041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318451404, states[0] = -94.884727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329883901, states[0] = -94.867527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340826893, states[0] = -94.841387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352280502, states[0] = -94.806193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363637039, states[0] = -63.061575, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1375152389, states[0] = -85.084702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386678744, states[0] = -94.636245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398016425, states[0] = 22.244182, states[40]= 0.015505
Saving checkpoint... 
Iteration: 1409736823, states[0] = -94.753880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420930048, states[0] = -94.880361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431632799, states[0] = -58.140728, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1447190069, states[0] = -94.668002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459027208, states[0] = 19.397216, states[40]= 0.006966
Saving checkpoint... 
Iteration: 1471927509, states[0] = -94.879759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483924534, states[0] = -94.879064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494589628, states[0] = -13.493445, states[40]= 0.001720
Saving checkpoint... 
Iteration: 1506511493, states[0] = -95.046464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1517168555, states[0] = -5.404965, states[40]= 0.003734
Saving checkpoint... 
Iteration: 1528568861, states[0] = -6.158729, states[40]= 0.003574
Saving checkpoint... 
Iteration: 1540702298, states[0] = -95.064079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1553571013, states[0] = -95.003438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1568239611, states[0] = -93.632216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1580292140, states[0] = -95.060439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1592154314, states[0] = 4.000665, states[40]= 0.005369
Saving checkpoint... 
Iteration: 1604357239, states[0] = -95.159959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1616818749, states[0] = -65.939297, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1629277834, states[0] = -95.180215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1641557394, states[0] = -95.162132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1653450949, states[0] = -94.926121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1665319271, states[0] = 21.208362, states[40]= 0.012459
Saving checkpoint... 
Iteration: 1677567380, states[0] = -95.172254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1690418742, states[0] = -95.114238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1701942835, states[0] = 10.524021, states[40]= 0.006043
Saving checkpoint... 
Iteration: 1713648742, states[0] = 7.253702, states[40]= 0.005696
Saving checkpoint... 
Iteration: 1725641605, states[0] = 11.176268, states[40]= 0.006126
Saving checkpoint... 
Iteration: 1737440142, states[0] = -93.972561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1749630791, states[0] = 16.521495, states[40]= 0.007274
Saving checkpoint... 
Iteration: 1761812488, states[0] = -95.104358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1777433451, states[0] = -95.135294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1793830982, states[0] = -85.696189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1810080213, states[0] = -7.520660, states[40]= 0.002978
Saving checkpoint... 
Iteration: 1820917130, states[0] = -94.918280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1834764248, states[0] = -94.817186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1851604237, states[0] = -28.875558, states[40]= 0.000490
Saving checkpoint... 
Iteration: 1864056633, states[0] = 7.723936, states[40]= 0.004981
Saving checkpoint... 
Iteration: 1874115301, states[0] = -39.606436, states[40]= 0.000128
Saving checkpoint... 
Iteration: 1884002222, states[0] = 43.686889, states[40]= 0.093976
Saving checkpoint... 
Iteration: 1895158410, states[0] = -92.159031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1906307813, states[0] = -94.831926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1916143567, states[0] = -71.631835, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1926956602, states[0] = -94.887126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1938262416, states[0] = -94.788310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1949584757, states[0] = -9.022963, states[40]= 0.002586
Saving checkpoint... 
Iteration: 1961029100, states[0] = 18.786415, states[40]= 0.006584
Saving checkpoint... 
Iteration: 1971731879, states[0] = -94.746521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1982507012, states[0] = 26.062820, states[40]= 0.101329
Saving checkpoint... 
Iteration: 1993543831, states[0] = 13.328899, states[40]= 0.005299
Saving checkpoint... 
Iteration: 2004678590, states[0] = -94.635370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2016432903, states[0] = -94.880739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2027146110, states[0] = -75.105192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2038540267, states[0] = 14.746679, states[40]= 0.005460
Saving checkpoint... 
Iteration: 2049998933, states[0] = -94.891259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2060750335, states[0] = -94.772220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2071971068, states[0] = -94.887541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2083292059, states[0] = -94.816102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2094276727, states[0] = -94.802081, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.767188
 - CaMKt in component CaMK (millimolar): 0.006661
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.670522
 - nass in component intracellular_ions (millimolar): 6.670581
 - ki in component intracellular_ions (millimolar): 145.310712
 - kss in component intracellular_ions (millimolar): 145.310693
 - cansr in component intracellular_ions (millimolar): 1.298355
 - cajsr in component intracellular_ions (millimolar): 1.261302
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003668
 - hf in component INa (dimensionless): 0.877644
 - hs in component INa (dimensionless): 0.877640
 - j in component INa (dimensionless): 0.877611
 - hsp in component INa (dimensionless): 0.721405
 - jp in component INa (dimensionless): 0.877591
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.707575
 - hLp in component INaL (dimensionless): 0.451644
 - a in component Ito (dimensionless): 0.000629
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.626038
 - ap in component Ito (dimensionless): 0.000321
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.701518
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.938076
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999897
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001557
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.331632
 - xs1 in component IKs (dimensionless): 0.232985
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997372
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:01:48 (94104): called boinc_finish(0)

</stderr_txt>
]]>


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