𝕏

Task 55433426

Name HuVeMOp_20240630130042325463_ORdGradInc_k_25-Pueyo_APDR-conf_360_1
Workunit 26323036
Created 30 Jun 2024, 11:01:10 UTC
Sent 30 Jun 2024, 12:37:17 UTC
Report deadline 3 Jul 2024, 22:13:17 UTC
Received 1 Jul 2024, 12:32:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238614
Run time 2 hours 31 min
CPU time 2 hours 30 min 36 sec
Validate state Valid
Credit 59.26
Device peak FLOPS 3.71 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.93 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.14.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630130042325463_ORdGradInc_k_25-Pueyo_APDR-conf_360.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630130042325463_ORdGradInc_k_25-Pueyo_APDR-conf_360_1_r1717236758_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630130042325463_ORdGradInc_k_25-Pueyo_APDR-conf_360_1_r1717236758_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 117.938814
     * GNaL_b in INaL: 0.007281
     * Gto_b in Ito: 0.095836
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031271
     * GKs_b in IKs: 0.001943
     * GK1_b in IK1: 0.177711
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 69.684007
     * GKb_b in IKb: 0.003706
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.022829
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11062996, states[0] = 6.659809, states[40]= 0.004691
Saving checkpoint... 
Iteration: 22545112, states[0] = 13.937338, states[40]= 0.004902
Saving checkpoint... 
Iteration: 35134244, states[0] = -48.476028, states[40]= 0.000042
Saving checkpoint... 
Iteration: 46502042, states[0] = 45.021228, states[40]= 0.099935
Saving checkpoint... 
Iteration: 59048910, states[0] = 13.161855, states[40]= 0.004856
Saving checkpoint... 
Iteration: 70970395, states[0] = -95.183068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85190230, states[0] = -94.959195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96984829, states[0] = -95.179960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109396233, states[0] = -95.159865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122389990, states[0] = -95.156886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134020583, states[0] = 21.203359, states[40]= 0.008626
Saving checkpoint... 
Iteration: 145291564, states[0] = -95.102296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157033868, states[0] = 18.258921, states[40]= 0.005331
Saving checkpoint... 
Iteration: 172457825, states[0] = -95.171756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184017719, states[0] = 21.588666, states[40]= 0.011735
Saving checkpoint... 
Iteration: 196365610, states[0] = -95.145990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207776501, states[0] = -95.087532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219557338, states[0] = 10.369239, states[40]= 0.004815
Saving checkpoint... 
Iteration: 231707375, states[0] = -94.988809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243339286, states[0] = -95.133447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254677033, states[0] = -94.800046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266218859, states[0] = -95.009908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277574672, states[0] = 3.018079, states[40]= 0.004529
Saving checkpoint... 
Iteration: 288732858, states[0] = -95.032938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299867801, states[0] = -95.146580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311590319, states[0] = -6.293634, states[40]= 0.003101
Saving checkpoint... 
Iteration: 323517205, states[0] = 21.648462, states[40]= 0.012593
Saving checkpoint... 
Iteration: 334503982, states[0] = 31.180075, states[40]= 0.171003
Saving checkpoint... 
Iteration: 349396601, states[0] = -95.156724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362472608, states[0] = -95.173560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374346033, states[0] = -95.136753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385670739, states[0] = -93.843038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398574603, states[0] = 3.052343, states[40]= 0.004532
Saving checkpoint... 
Iteration: 409885398, states[0] = -95.153035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422094948, states[0] = -9.913658, states[40]= 0.002333
Saving checkpoint... 
Iteration: 433620535, states[0] = -32.656499, states[40]= 0.000397
Saving checkpoint... 
Iteration: 444662790, states[0] = -85.362526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456060595, states[0] = 9.119785, states[40]= 0.004799
Saving checkpoint... 
Iteration: 467996707, states[0] = -95.176780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478905760, states[0] = -95.159333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490319550, states[0] = -95.121676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502320901, states[0] = -95.122529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514637443, states[0] = -49.447744, states[40]= 0.000036
Saving checkpoint... 
Iteration: 526819830, states[0] = -95.121828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537651093, states[0] = -65.648581, states[40]= 0.000002
Saving checkpoint... 
Iteration: 550386897, states[0] = -95.153440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563495257, states[0] = -95.176531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575275865, states[0] = -95.086454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586528146, states[0] = 19.758292, states[40]= 0.005958
Saving checkpoint... 
Iteration: 597898475, states[0] = -95.157110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609267285, states[0] = -95.077502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622358097, states[0] = -95.142225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634418259, states[0] = -95.162562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645175138, states[0] = -94.679679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656358304, states[0] = -95.142292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668279408, states[0] = -95.089848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679509402, states[0] = 22.649246, states[40]= 0.063339
Saving checkpoint... 
Iteration: 690785708, states[0] = -95.095690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703636957, states[0] = -48.918376, states[40]= 0.000039
Saving checkpoint... 
Iteration: 717491115, states[0] = -95.175894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729529754, states[0] = 19.368596, states[40]= 0.005730
Saving checkpoint... 
Iteration: 741611914, states[0] = -24.868818, states[40]= 0.000782
Saving checkpoint... 
Iteration: 753631876, states[0] = -43.554660, states[40]= 0.000089
Saving checkpoint... 
Iteration: 767634142, states[0] = -45.906738, states[40]= 0.000062
Saving checkpoint... 
Iteration: 780081640, states[0] = -0.649293, states[40]= 0.004129
Saving checkpoint... 
Iteration: 791438203, states[0] = -95.167045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803127156, states[0] = -38.866556, states[40]= 0.000176
Saving checkpoint... 
Iteration: 814212868, states[0] = -94.998668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826321196, states[0] = -95.122474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837469489, states[0] = -95.172721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848640582, states[0] = -52.925779, states[40]= 0.000021
Saving checkpoint... 
Iteration: 859853843, states[0] = -95.140127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874663892, states[0] = -87.293289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885781178, states[0] = -95.091370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896892490, states[0] = -95.155022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908218387, states[0] = -95.008566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920817587, states[0] = -95.120082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932087008, states[0] = -3.967947, states[40]= 0.003574
Saving checkpoint... 
Iteration: 948511948, states[0] = 22.153879, states[40]= 0.034207
Saving checkpoint... 
Iteration: 963420559, states[0] = -95.162892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974847886, states[0] = -95.137217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986286890, states[0] = -95.096528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998204082, states[0] = -94.981711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011460109, states[0] = -95.171049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027390353, states[0] = -95.154233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039282627, states[0] = -95.092612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052291989, states[0] = -95.100901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063921162, states[0] = -95.162966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076480249, states[0] = -95.174155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089113305, states[0] = -26.113533, states[40]= 0.000726
Saving checkpoint... 
Iteration: 1100687840, states[0] = -94.945109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112224069, states[0] = -95.018181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124568231, states[0] = 5.975879, states[40]= 0.004709
Saving checkpoint... 
Iteration: 1140156198, states[0] = -73.253991, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1152935369, states[0] = -95.166173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164129337, states[0] = -40.998634, states[40]= 0.000129
Saving checkpoint... 
Iteration: 1175338459, states[0] = -95.132254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186541896, states[0] = 15.810859, states[40]= 0.004957
Saving checkpoint... 
Iteration: 1197821179, states[0] = -95.122187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210782513, states[0] = -95.092378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223915776, states[0] = -95.161490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237256225, states[0] = -95.064307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253572988, states[0] = 3.825452, states[40]= 0.004589
Saving checkpoint... 
Iteration: 1265367039, states[0] = -95.145542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277163466, states[0] = -86.566036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288814622, states[0] = -95.117838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301762863, states[0] = -95.072069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313572866, states[0] = 3.882890, states[40]= 0.004593
Saving checkpoint... 
Iteration: 1325712120, states[0] = -94.996898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340550913, states[0] = 12.724876, states[40]= 0.004838
Saving checkpoint... 
Iteration: 1357967876, states[0] = -95.172079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369223688, states[0] = -95.017350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380480334, states[0] = -95.173942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394208424, states[0] = -94.989869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410729970, states[0] = -95.027572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422016949, states[0] = 21.675729, states[40]= 0.013067
Saving checkpoint... 
Iteration: 1436935874, states[0] = -95.166071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448642606, states[0] = -55.223549, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1461227728, states[0] = -95.023945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473433009, states[0] = -95.165420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485218379, states[0] = -95.008120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496702571, states[0] = -94.978330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1507994653, states[0] = -95.259929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1519757974, states[0] = -95.359933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1531922006, states[0] = -56.358544, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1546504546, states[0] = 30.502840, states[40]= 0.144339
Saving checkpoint... 
Iteration: 1561061808, states[0] = -95.211973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1572187841, states[0] = -95.283463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1583829037, states[0] = -68.084162, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1595139299, states[0] = 13.929649, states[40]= 0.005974
Saving checkpoint... 
Iteration: 1606641109, states[0] = -90.299837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1617035841, states[0] = 15.401706, states[40]= 0.006185
Saving checkpoint... 
Iteration: 1628551220, states[0] = -95.032343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1641282933, states[0] = -95.415725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1653828662, states[0] = -95.360384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1665457265, states[0] = -95.194748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1677727054, states[0] = -65.525815, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1689822758, states[0] = -95.352354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1702300828, states[0] = -33.632311, states[40]= 0.000342
Saving checkpoint... 
Iteration: 1713310981, states[0] = 22.999617, states[40]= 0.044111
Saving checkpoint... 
Iteration: 1726485578, states[0] = -95.418261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1738024625, states[0] = -62.064605, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1749511964, states[0] = -95.335699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1763342346, states[0] = -95.378027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1774425652, states[0] = -95.356556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1787432781, states[0] = 16.636803, states[40]= 0.006442
Saving checkpoint... 
Iteration: 1799478968, states[0] = -11.048778, states[40]= 0.002410
Saving checkpoint... 
Iteration: 1812522212, states[0] = 20.479353, states[40]= 0.007320
Saving checkpoint... 
Iteration: 1823698566, states[0] = -95.000418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1837746957, states[0] = -95.073127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1849422450, states[0] = -95.177406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1862820475, states[0] = -95.131155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1874604588, states[0] = -18.782083, states[40]= 0.001085
Saving checkpoint... 
Iteration: 1885660850, states[0] = -82.558694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1897296349, states[0] = -95.107410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1909388706, states[0] = -95.155465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1921422388, states[0] = -95.164310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1933521705, states[0] = 21.032264, states[40]= 0.007911
Saving checkpoint... 
Iteration: 1945474897, states[0] = -95.173521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1956488029, states[0] = -95.175125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1968260174, states[0] = -95.068851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1981283048, states[0] = -95.092535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1995189938, states[0] = -94.950581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2010574728, states[0] = 2.988049, states[40]= 0.004527
Saving checkpoint... 
Iteration: 2022729308, states[0] = -95.026084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2034282580, states[0] = -95.091821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2045731087, states[0] = -95.028834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2057565811, states[0] = 7.007888, states[40]= 0.004749
Saving checkpoint... 
Iteration: 2069747519, states[0] = -95.052557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2084017666, states[0] = 21.598353, states[40]= 0.011820
Saving checkpoint... 
Iteration: 2095954996, states[0] = -95.169286, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.051780
 - CaMKt in component CaMK (millimolar): 0.007525
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.607493
 - nass in component intracellular_ions (millimolar): 6.607556
 - ki in component intracellular_ions (millimolar): 145.362312
 - kss in component intracellular_ions (millimolar): 145.362291
 - cansr in component intracellular_ions (millimolar): 1.343018
 - cajsr in component intracellular_ions (millimolar): 1.303785
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003564
 - hf in component INa (dimensionless): 0.882578
 - hs in component INa (dimensionless): 0.882573
 - j in component INa (dimensionless): 0.882545
 - hsp in component INa (dimensionless): 0.730705
 - jp in component INa (dimensionless): 0.882525
 - mL in component INaL (dimensionless): 0.000048
 - hL in component INaL (dimensionless): 0.712456
 - hLp in component INaL (dimensionless): 0.452412
 - a in component Ito (dimensionless): 0.000617
 - iF in component Ito (dimensionless): 0.999873
 - iS in component Ito (dimensionless): 0.615415
 - ap in component Ito (dimensionless): 0.000314
 - iFp in component Ito (dimensionless): 0.999873
 - iSp in component Ito (dimensionless): 0.689462
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.930210
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999867
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001726
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.339119
 - xs1 in component IKs (dimensionless): 0.253975
 - xs2 in component IKs (dimensionless): 0.000086
 - xk1 in component IK1 (dimensionless): 0.997297
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
14:20:29 (94036): called boinc_finish(0)

</stderr_txt>
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