𝕏

Task 55432442

Name HuVeMOp_20240630124611120726_ORdGradInc_k_25-Pueyo_APDR-conf_738_0
Workunit 26322585
Created 30 Jun 2024, 10:46:29 UTC
Sent 30 Jun 2024, 12:20:38 UTC
Report deadline 3 Jul 2024, 21:56:38 UTC
Received 30 Jun 2024, 14:52:40 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241023
Run time 2 hours 28 min 52 sec
CPU time 2 hours 26 min 38 sec
Validate state Valid
Credit 61.21
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.25 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630124611120726_ORdGradInc_k_25-Pueyo_APDR-conf_738.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630124611120726_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r1038649289_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630124611120726_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r1038649289_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.363726
     * GNaL_b in INaL: 0.004556
     * Gto_b in Ito: 0.090859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.001780
     * GK1_b in IK1: 0.170149
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256397
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13907130, states[0] = -95.112624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28474746, states[0] = -95.095561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43334721, states[0] = -95.037398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58454434, states[0] = -95.066118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73727194, states[0] = -94.917436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88684232, states[0] = -94.829818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103415801, states[0] = -95.045774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117729403, states[0] = -94.913118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132744690, states[0] = -94.934149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147784706, states[0] = -94.977239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162548335, states[0] = 10.691808, states[40]= 0.004845
Saving checkpoint... 
Iteration: 177654250, states[0] = -90.575257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192909374, states[0] = -95.040074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208164868, states[0] = -94.618569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223439003, states[0] = -95.046795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238742136, states[0] = -94.928864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254070340, states[0] = 0.554736, states[40]= 0.004305
Saving checkpoint... 
Iteration: 269350547, states[0] = -95.018802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284556312, states[0] = 7.397751, states[40]= 0.004757
Saving checkpoint... 
Iteration: 299808194, states[0] = -94.994494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314983093, states[0] = -95.053958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329797065, states[0] = -94.986230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345123506, states[0] = -48.566196, states[40]= 0.000034
Saving checkpoint... 
Iteration: 360033177, states[0] = 16.318599, states[40]= 0.005388
Saving checkpoint... 
Iteration: 374370847, states[0] = -95.027255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388933397, states[0] = -95.045378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403296043, states[0] = -94.985366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417427138, states[0] = -95.043978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431384543, states[0] = -95.032129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446040497, states[0] = 13.725818, states[40]= 0.005008
Saving checkpoint... 
Iteration: 460670807, states[0] = -94.769265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475106993, states[0] = -31.538259, states[40]= 0.000376
Saving checkpoint... 
Iteration: 488704064, states[0] = -94.865195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502217259, states[0] = -94.889835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516026722, states[0] = 18.293194, states[40]= 0.006174
Saving checkpoint... 
Iteration: 529525030, states[0] = 18.745693, states[40]= 0.006547
Saving checkpoint... 
Iteration: 543101314, states[0] = -25.906104, states[40]= 0.000632
Saving checkpoint... 
Iteration: 556711020, states[0] = -94.878504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570746941, states[0] = -94.934953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585274989, states[0] = -94.966703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600021035, states[0] = 19.685216, states[40]= 0.008150
Saving checkpoint... 
Iteration: 614597819, states[0] = -22.448645, states[40]= 0.000801
Saving checkpoint... 
Iteration: 629240336, states[0] = -94.925998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643809704, states[0] = -94.995270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658929380, states[0] = -95.044298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674408812, states[0] = -95.039256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689318235, states[0] = -95.000876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703650531, states[0] = -85.157014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717979717, states[0] = -95.053184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732526931, states[0] = 18.235275, states[40]= 0.006135
Saving checkpoint... 
Iteration: 747047603, states[0] = 10.995920, states[40]= 0.004854
Saving checkpoint... 
Iteration: 761465677, states[0] = -95.051065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776038955, states[0] = 14.295128, states[40]= 0.005063
Saving checkpoint... 
Iteration: 790564800, states[0] = 3.483932, states[40]= 0.004574
Saving checkpoint... 
Iteration: 805119492, states[0] = -44.267010, states[40]= 0.000066
Saving checkpoint... 
Iteration: 819434618, states[0] = -95.045312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833623511, states[0] = -48.570939, states[40]= 0.000034
Saving checkpoint... 
Iteration: 847735157, states[0] = -94.918411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861812616, states[0] = -94.997084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876058990, states[0] = 6.218520, states[40]= 0.004718
Saving checkpoint... 
Iteration: 890014161, states[0] = 20.861517, states[40]= 0.020137
Saving checkpoint... 
Iteration: 903814367, states[0] = -94.998215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917591724, states[0] = -16.425014, states[40]= 0.001288
Saving checkpoint... 
Iteration: 931466189, states[0] = -95.051018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945265264, states[0] = -94.956438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959354767, states[0] = -95.020167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974003205, states[0] = 33.627520, states[40]= 0.163667
Saving checkpoint... 
Iteration: 988417771, states[0] = -95.041328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002494054, states[0] = -95.054833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017026463, states[0] = 18.364534, states[40]= 0.006224
Saving checkpoint... 
Iteration: 1031872469, states[0] = -95.027373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046479707, states[0] = -95.052935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061244647, states[0] = -94.931554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075720380, states[0] = -94.894800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090200586, states[0] = -94.857754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104675661, states[0] = -94.798309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119271567, states[0] = -94.962895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133680558, states[0] = -94.813251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148005311, states[0] = 25.665748, states[40]= 0.151320
Saving checkpoint... 
Iteration: 1162611812, states[0] = -36.357595, states[40]= 0.000207
Saving checkpoint... 
Iteration: 1177219151, states[0] = -94.892615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191588435, states[0] = -13.230968, states[40]= 0.001744
Saving checkpoint... 
Iteration: 1206212072, states[0] = -94.879959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220469366, states[0] = -95.051294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234561332, states[0] = 5.148759, states[40]= 0.004672
Saving checkpoint... 
Iteration: 1248899370, states[0] = -95.036172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263553864, states[0] = 8.442790, states[40]= 0.004785
Saving checkpoint... 
Iteration: 1278083408, states[0] = -8.633205, states[40]= 0.002634
Saving checkpoint... 
Iteration: 1292545097, states[0] = 11.978119, states[40]= 0.004894
Saving checkpoint... 
Iteration: 1306815075, states[0] = -94.998374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320886108, states[0] = -95.031980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335148068, states[0] = -80.752371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349516706, states[0] = 20.482897, states[40]= 0.013021
Saving checkpoint... 
Iteration: 1363760579, states[0] = -94.950939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378129250, states[0] = -54.891466, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1393437880, states[0] = -95.045559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408686887, states[0] = -94.828129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423928494, states[0] = -95.043523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438736009, states[0] = -94.919210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453365049, states[0] = -95.024158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468036746, states[0] = 15.091711, states[40]= 0.005162
Saving checkpoint... 
Iteration: 1482625875, states[0] = -51.149947, states[40]= 0.000022
Saving checkpoint... 
Iteration: 1497457036, states[0] = -95.049083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1512181709, states[0] = -95.131237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1526911077, states[0] = -95.201147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1541521512, states[0] = -71.230967, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1556290509, states[0] = -95.181588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1570954389, states[0] = -95.094212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1585672434, states[0] = -95.148263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600270942, states[0] = -10.616693, states[40]= 0.002504
Saving checkpoint... 
Iteration: 1614795235, states[0] = -95.201265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1629529650, states[0] = -95.257388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1644371258, states[0] = -11.056448, states[40]= 0.002408
Saving checkpoint... 
Iteration: 1659030916, states[0] = 15.400460, states[40]= 0.006565
Saving checkpoint... 
Iteration: 1673892928, states[0] = -95.198205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1688856847, states[0] = -95.110197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1703952540, states[0] = -95.284991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1719128306, states[0] = -85.645856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1734281504, states[0] = -95.310488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1749564364, states[0] = -95.296385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1764686809, states[0] = -28.854392, states[40]= 0.000489
Saving checkpoint... 
Iteration: 1779470540, states[0] = -95.148003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1793980274, states[0] = -95.309532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1808729565, states[0] = -94.954684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1823652968, states[0] = -91.676905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1838553942, states[0] = 7.990037, states[40]= 0.004781
Saving checkpoint... 
Iteration: 1853489740, states[0] = -95.067415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1868419912, states[0] = -95.049984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1883694810, states[0] = -94.850846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1898838797, states[0] = -95.015310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914039597, states[0] = 14.025007, states[40]= 0.005038
Saving checkpoint... 
Iteration: 1929019428, states[0] = 19.994786, states[40]= 0.009350
Saving checkpoint... 
Iteration: 1944085766, states[0] = -10.779904, states[40]= 0.002192
Saving checkpoint... 
Iteration: 1958682207, states[0] = -94.817326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1973445924, states[0] = -95.047042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1988303709, states[0] = -94.990185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2003045472, states[0] = 11.829940, states[40]= 0.004887
Saving checkpoint... 
Iteration: 2017665326, states[0] = -94.639926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2032403347, states[0] = -95.036728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047091723, states[0] = -16.425790, states[40]= 0.001288
Saving checkpoint... 
Iteration: 2061999806, states[0] = -95.054675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2076741620, states[0] = -94.926631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2091569282, states[0] = 1.146885, states[40]= 0.004370
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.930525
 - CaMKt in component CaMK (millimolar): 0.007119
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.594707
 - nass in component intracellular_ions (millimolar): 6.594768
 - ki in component intracellular_ions (millimolar): 145.378247
 - kss in component intracellular_ions (millimolar): 145.378227
 - cansr in component intracellular_ions (millimolar): 1.327244
 - cajsr in component intracellular_ions (millimolar): 1.289631
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003608
 - hf in component INa (dimensionless): 0.880497
 - hs in component INa (dimensionless): 0.880493
 - j in component INa (dimensionless): 0.880464
 - hsp in component INa (dimensionless): 0.726767
 - jp in component INa (dimensionless): 0.880445
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.712202
 - hLp in component INaL (dimensionless): 0.457572
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.628338
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.705188
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.941730
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999906
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001662
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.306894
 - xs1 in component IKs (dimensionless): 0.229134
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997330
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:52:29 (595997): called boinc_finish(0)

</stderr_txt>
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