𝕏

Task 55432263

Name HuVeMOp_20240630124611120726_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_529_1
Workunit 26322495
Created 30 Jun 2024, 10:46:24 UTC
Sent 30 Jun 2024, 12:18:03 UTC
Report deadline 3 Jul 2024, 15:10:51 UTC
Received 1 Jul 2024, 3:22:22 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 218427
Run time 2 hours 8 min 6 sec
CPU time 2 hours 3 min 47 sec
Validate state Valid
Credit 48.80
Device peak FLOPS 4.19 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.84 MB
Peak swap size 32.57 GB
Peak disk usage 0.06 MB

Stderr output

<core_client_version>7.16.19</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630124611120726_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_529.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630124611120726_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_529_1_r1935087477_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630124611120726_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_529_1_r1935087477_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 94.820953
     * GNaL_b in INaL: 0.005534
     * Gto_b in Ito: 0.073406
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033818
     * GKs_b in IKs: 0.001884
     * GK1_b in IK1: 0.042827
     * Gncx_b in INaCa_i: 0.000956
     * Pnak_b in INaK: 68.299809
     * GKb_b in IKb: 0.003885
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.041955
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13847794, states[0] = -91.821298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27748534, states[0] = -90.540803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41645064, states[0] = -60.096173, states[40]= 0.000012
Saving checkpoint... 
Iteration: 55562446, states[0] = 11.263461, states[40]= 0.003632
Saving checkpoint... 
Iteration: 69458591, states[0] = -91.659467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83387318, states[0] = -91.522286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97283633, states[0] = -90.938565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111236110, states[0] = -89.566607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125149996, states[0] = -62.805878, states[40]= 0.000007
Saving checkpoint... 
Iteration: 139099561, states[0] = -15.408049, states[40]= 0.001584
Saving checkpoint... 
Iteration: 153022591, states[0] = 26.898806, states[40]= 0.001867
Saving checkpoint... 
Iteration: 167017611, states[0] = 27.967238, states[40]= 0.004455
Saving checkpoint... 
Iteration: 180946878, states[0] = -91.588203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194928278, states[0] = -91.562804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208820856, states[0] = -91.217561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222769855, states[0] = -90.709619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236617062, states[0] = -33.492315, states[40]= 0.000592
Saving checkpoint... 
Iteration: 250537149, states[0] = 22.049875, states[40]= 0.001867
Saving checkpoint... 
Iteration: 263966464, states[0] = -91.604828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277212147, states[0] = -86.841644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290741627, states[0] = -89.846739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304673438, states[0] = -75.278358, states[40]= 0.000001
Saving checkpoint... 
Iteration: 318666447, states[0] = -72.104525, states[40]= 0.000001
Saving checkpoint... 
Iteration: 332524358, states[0] = 26.428178, states[40]= 0.001649
Saving checkpoint... 
Iteration: 346526331, states[0] = 25.846023, states[40]= 0.001553
Saving checkpoint... 
Iteration: 360472581, states[0] = -91.609116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374436605, states[0] = -91.571791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388247688, states[0] = -90.119585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401954464, states[0] = -91.592627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415618116, states[0] = -34.544384, states[40]= 0.000534
Saving checkpoint... 
Iteration: 429306372, states[0] = -91.118405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442901011, states[0] = -91.510880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456556046, states[0] = 14.343251, states[40]= 0.003177
Saving checkpoint... 
Iteration: 470302816, states[0] = -91.090765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483960168, states[0] = -91.597877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497665988, states[0] = -71.880743, states[40]= 0.000001
Saving checkpoint... 
Iteration: 511345447, states[0] = -91.339372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525001051, states[0] = 44.077698, states[40]= 0.203128
Saving checkpoint... 
Iteration: 538686401, states[0] = -80.237674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552396999, states[0] = -91.501623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566093873, states[0] = -9.419097, states[40]= 0.002663
Saving checkpoint... 
Iteration: 579836679, states[0] = -91.299264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593528861, states[0] = 25.037389, states[40]= 0.001548
Saving checkpoint... 
Iteration: 607163949, states[0] = -70.868432, states[40]= 0.000002
Saving checkpoint... 
Iteration: 620844065, states[0] = -91.332893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634512894, states[0] = 28.500356, states[40]= 0.017649
Saving checkpoint... 
Iteration: 648145396, states[0] = -59.473877, states[40]= 0.000014
Saving checkpoint... 
Iteration: 661825507, states[0] = -91.240975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675513303, states[0] = 28.472973, states[40]= 0.015494
Saving checkpoint... 
Iteration: 689175143, states[0] = -75.993050, states[40]= 0.000001
Saving checkpoint... 
Iteration: 702841230, states[0] = -91.319919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716515829, states[0] = 28.230031, states[40]= 0.007198
Saving checkpoint... 
Iteration: 730167924, states[0] = -72.805690, states[40]= 0.000001
Saving checkpoint... 
Iteration: 743852983, states[0] = -91.369095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757238730, states[0] = -89.685663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770876127, states[0] = -91.447153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784527126, states[0] = 25.599360, states[40]= 0.001541
Saving checkpoint... 
Iteration: 798231514, states[0] = -89.193253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811907714, states[0] = -91.522875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825608469, states[0] = -24.740590, states[40]= 0.000984
Saving checkpoint... 
Iteration: 839229981, states[0] = -89.067118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852881443, states[0] = -91.461759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866535781, states[0] = 22.569926, states[40]= 0.001797
Saving checkpoint... 
Iteration: 880228200, states[0] = -88.909822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893886366, states[0] = -91.474582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907595121, states[0] = -10.682545, states[40]= 0.002399
Saving checkpoint... 
Iteration: 921293998, states[0] = -91.012358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934971322, states[0] = -91.605518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948674223, states[0] = -75.607153, states[40]= 0.000001
Saving checkpoint... 
Iteration: 962398671, states[0] = -91.503469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976090697, states[0] = -6.360232, states[40]= 0.003312
Saving checkpoint... 
Iteration: 989830376, states[0] = -91.265783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003404043, states[0] = -91.514667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017068563, states[0] = 8.477964, states[40]= 0.004050
Saving checkpoint... 
Iteration: 1030590650, states[0] = -6.316816, states[40]= 0.003321
Saving checkpoint... 
Iteration: 1044309327, states[0] = -91.137103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057186832, states[0] = -80.380492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070751582, states[0] = -90.258418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084382226, states[0] = -91.462830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098089135, states[0] = -4.957410, states[40]= 0.003588
Saving checkpoint... 
Iteration: 1111762322, states[0] = -90.554901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125471686, states[0] = -91.604948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139121408, states[0] = -37.821621, states[40]= 0.000371
Saving checkpoint... 
Iteration: 1152811069, states[0] = -91.148842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166482856, states[0] = -91.612801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179781913, states[0] = -90.880826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191950541, states[0] = -91.584901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205890893, states[0] = -91.484439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219766829, states[0] = -90.648074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233681354, states[0] = -78.433432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247649482, states[0] = -62.377854, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1261565560, states[0] = 9.977207, states[40]= 0.003869
Saving checkpoint... 
Iteration: 1275487950, states[0] = -91.615493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289453505, states[0] = -91.587624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303388134, states[0] = -91.477202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317340416, states[0] = -91.313390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331298518, states[0] = -91.051112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345296822, states[0] = -91.036193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359276331, states[0] = -90.805433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373216513, states[0] = -87.530743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387226575, states[0] = -88.752494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401185007, states[0] = -79.751334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415156917, states[0] = -67.053546, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1429071230, states[0] = 7.083558, states[40]= 0.004185
Saving checkpoint... 
Iteration: 1442967630, states[0] = -91.600212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456918665, states[0] = -91.539889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470860025, states[0] = -91.392005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484774343, states[0] = -90.775381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498744161, states[0] = -89.962655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1512440988, states[0] = -91.250485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1526129576, states[0] = -91.706990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1539575711, states[0] = -90.556665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1553067427, states[0] = -90.367693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1566672935, states[0] = -90.355365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1580230923, states[0] = -82.659140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1593746245, states[0] = -83.675922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1607239761, states[0] = -82.221482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1620731158, states[0] = -88.806232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1634030498, states[0] = -88.100736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647503875, states[0] = 30.721502, states[40]= 0.334012
Saving checkpoint... 
Iteration: 1660967104, states[0] = -88.215343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1674409422, states[0] = -87.620078, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -87.368973
 - CaMKt in component CaMK (millimolar): 0.001062
 - cass in component intracellular_ions (millimolar): 0.000085
 - nai in component intracellular_ions (millimolar): 6.210391
 - nass in component intracellular_ions (millimolar): 6.210472
 - ki in component intracellular_ions (millimolar): 145.696454
 - kss in component intracellular_ions (millimolar): 145.696442
 - cansr in component intracellular_ions (millimolar): 1.523083
 - cajsr in component intracellular_ions (millimolar): 1.523153
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.007730
 - hf in component INa (dimensionless): 0.680198
 - hs in component INa (dimensionless): 0.680208
 - j in component INa (dimensionless): 0.680255
 - hsp in component INa (dimensionless): 0.434402
 - jp in component INa (dimensionless): 0.680281
 - mL in component INaL (dimensionless): 0.000207
 - hL in component INaL (dimensionless): 0.496504
 - hLp in component INaL (dimensionless): 0.302200
 - a in component Ito (dimensionless): 0.001036
 - iF in component Ito (dimensionless): 0.999513
 - iS in component Ito (dimensionless): 0.995489
 - ap in component Ito (dimensionless): 0.000528
 - iFp in component Ito (dimensionless): 0.999513
 - iSp in component Ito (dimensionless): 0.997679
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998910
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002694
 - xrf in component IKr (dimensionless): 0.000009
 - xrs in component IKr (dimensionless): 0.007434
 - xs1 in component IKs (dimensionless): 0.022829
 - xs2 in component IKs (dimensionless): 0.000204
 - xk1 in component IK1 (dimensionless): 0.998736
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
20:18:04 (66529): called boinc_finish(0)

</stderr_txt>
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