𝕏

Task 55431240

Name HuVeMOp_20240630124543266104_ORdGradInc_k_25-Pueyo_APDR-conf_813_0
Workunit 26321985
Created 30 Jun 2024, 10:45:48 UTC
Sent 30 Jun 2024, 12:05:51 UTC
Report deadline 3 Jul 2024, 21:41:51 UTC
Received 30 Jun 2024, 20:58:38 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 219692
Run time 2 hours 52 min 9 sec
CPU time 2 hours 52 min 9 sec
Validate state Valid
Credit 60.99
Device peak FLOPS 2.80 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.68 MB
Peak swap size 6.20 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630124543266104_ORdGradInc_k_25-Pueyo_APDR-conf_813.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630124543266104_ORdGradInc_k_25-Pueyo_APDR-conf_813_0_r1295079830_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630124543266104_ORdGradInc_k_25-Pueyo_APDR-conf_813_0_r1295079830_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.409839
     * GNaL_b in INaL: 0.004957
     * Gto_b in Ito: 0.096056
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.029759
     * GKs_b in IKs: 0.001962
     * GK1_b in IK1: 0.159468
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 71.576220
     * GKb_b in IKb: 0.003783
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.021100
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11766525, states[0] = -94.878621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23680992, states[0] = -94.648723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35525993, states[0] = 18.886143, states[40]= 0.006099
Saving checkpoint... 
Iteration: 47568268, states[0] = 3.834965, states[40]= 0.004572
Saving checkpoint... 
Iteration: 59556058, states[0] = 9.150430, states[40]= 0.004751
Saving checkpoint... 
Iteration: 71448465, states[0] = -94.894873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83460693, states[0] = -94.893465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95245178, states[0] = -94.754700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106979718, states[0] = -94.892291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118971610, states[0] = -94.889637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130902068, states[0] = -94.871933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142919472, states[0] = -94.876555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154521256, states[0] = 20.218917, states[40]= 0.007822
Saving checkpoint... 
Iteration: 166535783, states[0] = 16.562583, states[40]= 0.005095
Saving checkpoint... 
Iteration: 178559383, states[0] = 8.149684, states[40]= 0.004729
Saving checkpoint... 
Iteration: 190523816, states[0] = 19.737247, states[40]= 0.006713
Saving checkpoint... 
Iteration: 202335329, states[0] = -94.839422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214374757, states[0] = -94.859686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226434264, states[0] = -94.878980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238443482, states[0] = -94.881079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250423726, states[0] = -94.876206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262426539, states[0] = -94.876923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274463656, states[0] = -94.885091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286177743, states[0] = -94.294717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298154015, states[0] = -69.373924, states[40]= 0.000001
Saving checkpoint... 
Iteration: 310174818, states[0] = -93.852124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322041456, states[0] = 14.722277, states[40]= 0.004886
Saving checkpoint... 
Iteration: 333972303, states[0] = -94.886551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345991187, states[0] = -94.889478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357911866, states[0] = -94.872698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369678186, states[0] = -94.334840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381333520, states[0] = -94.837891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393312659, states[0] = -94.823251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405460829, states[0] = -94.884428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417212431, states[0] = -94.689144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429362306, states[0] = -94.853720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441325855, states[0] = -94.832812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453535155, states[0] = 16.765968, states[40]= 0.005129
Saving checkpoint... 
Iteration: 465681809, states[0] = -94.527625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477636194, states[0] = -50.292714, states[40]= 0.000029
Saving checkpoint... 
Iteration: 489686445, states[0] = -94.608811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501856807, states[0] = -94.850960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513769734, states[0] = -94.781468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525773431, states[0] = -94.785806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537879811, states[0] = -94.861345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550114384, states[0] = -30.010006, states[40]= 0.000507
Saving checkpoint... 
Iteration: 562226209, states[0] = -94.715962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575215265, states[0] = -94.694803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588847970, states[0] = -94.846239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602591005, states[0] = -9.382882, states[40]= 0.002438
Saving checkpoint... 
Iteration: 616158735, states[0] = -75.934800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629749105, states[0] = -94.753856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642856304, states[0] = -94.850592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656088412, states[0] = -7.332794, states[40]= 0.002871
Saving checkpoint... 
Iteration: 669293355, states[0] = -94.806498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682938553, states[0] = -94.879511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696527491, states[0] = 18.907304, states[40]= 0.005874
Saving checkpoint... 
Iteration: 710155896, states[0] = -71.849009, states[40]= 0.000001
Saving checkpoint... 
Iteration: 721926503, states[0] = -94.876501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733916691, states[0] = -94.873806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745860008, states[0] = -94.852353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757997768, states[0] = -94.890049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769927099, states[0] = -94.876618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781987514, states[0] = -94.888593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794024902, states[0] = 19.510029, states[40]= 0.006401
Saving checkpoint... 
Iteration: 806079466, states[0] = -1.322594, states[40]= 0.004012
Saving checkpoint... 
Iteration: 818193053, states[0] = -94.643510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820409229, states[0] = -94.871523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832397853, states[0] = -94.867827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844305065, states[0] = -94.816763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856212749, states[0] = -94.689443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868154001, states[0] = -69.353773, states[40]= 0.000001
Saving checkpoint... 
Iteration: 879984129, states[0] = -94.888008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891685330, states[0] = -94.596671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903762742, states[0] = -94.772466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915748175, states[0] = -94.752243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927748101, states[0] = -94.752123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939812622, states[0] = -94.822781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951755808, states[0] = -94.763177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963233650, states[0] = -94.728894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975195115, states[0] = -94.649481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987337613, states[0] = -94.839937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999168133, states[0] = -90.037827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011184904, states[0] = -94.591150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022962124, states[0] = -94.884175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034883755, states[0] = -94.862513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046978470, states[0] = -94.886991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059039592, states[0] = 15.346839, states[40]= 0.004938
Saving checkpoint... 
Iteration: 1071076027, states[0] = 0.598376, states[40]= 0.004267
Saving checkpoint... 
Iteration: 1083158601, states[0] = -75.730963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095247448, states[0] = -94.751009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107071708, states[0] = 2.790141, states[40]= 0.004481
Saving checkpoint... 
Iteration: 1118907150, states[0] = -94.870638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130846230, states[0] = -94.844839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142736675, states[0] = -94.733880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154850668, states[0] = -94.847245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167047419, states[0] = 12.646978, states[40]= 0.004793
Saving checkpoint... 
Iteration: 1179056587, states[0] = 9.254755, states[40]= 0.004746
Saving checkpoint... 
Iteration: 1191059562, states[0] = 8.087921, states[40]= 0.004728
Saving checkpoint... 
Iteration: 1203264527, states[0] = -94.774501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215287183, states[0] = -94.800056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227491229, states[0] = -94.888772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239593654, states[0] = -11.596830, states[40]= 0.002002
Saving checkpoint... 
Iteration: 1251761461, states[0] = -94.770524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263911441, states[0] = -94.871839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275995186, states[0] = -94.889284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288009172, states[0] = 21.928284, states[40]= 0.064821
Saving checkpoint... 
Iteration: 1299679272, states[0] = -94.413694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311843965, states[0] = -94.843415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323979971, states[0] = -94.887007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335921065, states[0] = -94.874550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347855284, states[0] = -94.849505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359626456, states[0] = -40.948139, states[40]= 0.000123
Saving checkpoint... 
Iteration: 1371725752, states[0] = -94.714461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383737359, states[0] = -94.734824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395187115, states[0] = -94.613825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406902634, states[0] = -94.868962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418885614, states[0] = -94.862923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430661135, states[0] = -79.711890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442398552, states[0] = -94.867574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454208440, states[0] = -94.679939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466084355, states[0] = -4.403536, states[40]= 0.003477
Saving checkpoint... 
Iteration: 1477906553, states[0] = -94.870162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489774979, states[0] = -94.786800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1501665474, states[0] = -94.882487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1513477274, states[0] = -95.112143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1525457459, states[0] = -95.105112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537167125, states[0] = -95.125483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1549200015, states[0] = -93.301625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1561240261, states[0] = 12.666622, states[40]= 0.005804
Saving checkpoint... 
Iteration: 1573170398, states[0] = -95.144801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1585273986, states[0] = -8.206967, states[40]= 0.003050
Saving checkpoint... 
Iteration: 1596963065, states[0] = 0.327609, states[40]= 0.004805
Saving checkpoint... 
Iteration: 1608454693, states[0] = -94.770353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1620074828, states[0] = -9.128814, states[40]= 0.002833
Saving checkpoint... 
Iteration: 1631929459, states[0] = -95.100705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1643556626, states[0] = -94.851221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1655185514, states[0] = -20.128921, states[40]= 0.001050
Saving checkpoint... 
Iteration: 1666824053, states[0] = 19.034511, states[40]= 0.007812
Saving checkpoint... 
Iteration: 1678540048, states[0] = 12.621965, states[40]= 0.005811
Saving checkpoint... 
Iteration: 1690087293, states[0] = -95.019427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1701998325, states[0] = -33.484448, states[40]= 0.000334
Saving checkpoint... 
Iteration: 1713597961, states[0] = -95.175096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1725556070, states[0] = -95.136853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1737366151, states[0] = -1.889658, states[40]= 0.004451
Saving checkpoint... 
Iteration: 1749414417, states[0] = -50.817030, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1761489713, states[0] = -95.025275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1773306801, states[0] = 24.634334, states[40]= 0.109863
Saving checkpoint... 
Iteration: 1785318028, states[0] = 20.728535, states[40]= 0.012193
Saving checkpoint... 
Iteration: 1797342463, states[0] = 11.493619, states[40]= 0.005711
Saving checkpoint... 
Iteration: 1809468695, states[0] = -94.935790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1821131980, states[0] = -48.660750, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1832775364, states[0] = -94.814679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1844336406, states[0] = -94.858108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856464843, states[0] = -94.897552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1868457226, states[0] = -94.891984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880471287, states[0] = -94.891680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1892286377, states[0] = -94.803340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1904272986, states[0] = -94.787410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1916310022, states[0] = -94.822164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1928329661, states[0] = -94.835680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1940256830, states[0] = -94.764843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1952258947, states[0] = -94.767355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1964223208, states[0] = -94.709704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1976095530, states[0] = -13.237952, states[40]= 0.001719
Saving checkpoint... 
Iteration: 1988044984, states[0] = 13.502971, states[40]= 0.004820
Saving checkpoint... 
Iteration: 1999814181, states[0] = -94.823243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2011657135, states[0] = -73.588812, states[40]= 0.000001
Saving checkpoint... 
Iteration: 2023615342, states[0] = -30.869116, states[40]= 0.000464
Saving checkpoint... 
Iteration: 2035684040, states[0] = -94.577379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047656570, states[0] = -72.781101, states[40]= 0.000001
Saving checkpoint... 
Iteration: 2059503039, states[0] = 35.054295, states[40]= 0.162367
Saving checkpoint... 
Iteration: 2071609243, states[0] = -25.433389, states[40]= 0.000733
Saving checkpoint... 
Iteration: 2083681673, states[0] = -94.521935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2095721578, states[0] = -94.705942, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.765075
 - CaMKt in component CaMK (millimolar): 0.007500
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.588683
 - nass in component intracellular_ions (millimolar): 6.588743
 - ki in component intracellular_ions (millimolar): 145.380757
 - kss in component intracellular_ions (millimolar): 145.380738
 - cansr in component intracellular_ions (millimolar): 1.342019
 - cajsr in component intracellular_ions (millimolar): 1.303155
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003669
 - hf in component INa (dimensionless): 0.877607
 - hs in component INa (dimensionless): 0.877602
 - j in component INa (dimensionless): 0.877569
 - hsp in component INa (dimensionless): 0.721332
 - jp in component INa (dimensionless): 0.877546
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.704637
 - hLp in component INaL (dimensionless): 0.443105
 - a in component Ito (dimensionless): 0.000629
 - iF in component Ito (dimensionless): 0.999866
 - iS in component Ito (dimensionless): 0.614825
 - ap in component Ito (dimensionless): 0.000321
 - iFp in component Ito (dimensionless): 0.999866
 - iSp in component Ito (dimensionless): 0.688712
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935098
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999881
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001712
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330047
 - xs1 in component IKs (dimensionless): 0.245377
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997373
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:57:55 (10584): called boinc_finish(0)

</stderr_txt>
]]>


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