𝕏

Task 55431108

Name HuVeMOp_20240630124543266104_ORdGradInc_k_25-Pueyo_APDR-conf_701_0
Workunit 26321919
Created 30 Jun 2024, 10:45:47 UTC
Sent 30 Jun 2024, 12:06:41 UTC
Report deadline 3 Jul 2024, 21:42:41 UTC
Received 30 Jun 2024, 17:44:15 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216773
Run time 1 hours 2 min 56 sec
CPU time 51 min 27 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 5.90 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.25 MB
Peak swap size 5.32 MB
Peak disk usage 0.20 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630124543266104_ORdGradInc_k_25-Pueyo_APDR-conf_701.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630124543266104_ORdGradInc_k_25-Pueyo_APDR-conf_701_0_r99551952_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630124543266104_ORdGradInc_k_25-Pueyo_APDR-conf_701_0_r99551952_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 108.999586
     * GNaL_b in INaL: 0.004800
     * Gto_b in Ito: 0.075638
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.029881
     * GKs_b in IKs: 0.001909
     * GK1_b in IK1: 0.181524
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 70.389390
     * GKb_b in IKb: 0.003725
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038558
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 19955246, states[0] = -95.098142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38796962, states[0] = -95.017343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57858520, states[0] = -95.036051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76549203, states[0] = 11.492155, states[40]= 0.005168
Saving checkpoint... 
Iteration: 97123585, states[0] = -43.607467, states[40]= 0.000073
Saving checkpoint... 
Iteration: 119253022, states[0] = -94.952293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138757643, states[0] = -94.956000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157399267, states[0] = -95.033564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177813942, states[0] = -94.999173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198037760, states[0] = 16.120209, states[40]= 0.005665
Saving checkpoint... 
Iteration: 215633319, states[0] = -53.419988, states[40]= 0.000015
Saving checkpoint... 
Iteration: 234264274, states[0] = -94.961147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252473132, states[0] = -95.046592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270544517, states[0] = 13.540914, states[40]= 0.005308
Saving checkpoint... 
Iteration: 290577341, states[0] = -1.600851, states[40]= 0.004060
Saving checkpoint... 
Iteration: 311021886, states[0] = 21.255378, states[40]= 0.009117
Saving checkpoint... 
Iteration: 329665538, states[0] = -94.288055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348475357, states[0] = -95.046778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367053785, states[0] = 9.814469, states[40]= 0.005064
Saving checkpoint... 
Iteration: 387414706, states[0] = -95.036314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405508075, states[0] = 25.516688, states[40]= 0.081375
Saving checkpoint... 
Iteration: 426110952, states[0] = -30.849320, states[40]= 0.000420
Saving checkpoint... 
Iteration: 445086081, states[0] = -7.784296, states[40]= 0.002827
Saving checkpoint... 
Iteration: 465852836, states[0] = -95.017462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484284396, states[0] = -94.978453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502186253, states[0] = -94.848588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521458386, states[0] = -95.044322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539442277, states[0] = -95.041702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558075543, states[0] = -0.525343, states[40]= 0.004226
Saving checkpoint... 
Iteration: 576824529, states[0] = -95.004356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595088996, states[0] = -10.234777, states[40]= 0.002306
Saving checkpoint... 
Iteration: 613735485, states[0] = -94.928575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633250289, states[0] = -94.946339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658814194, states[0] = -94.998582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686582111, states[0] = -4.758655, states[40]= 0.003474
Saving checkpoint... 
Iteration: 712256243, states[0] = -94.952722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732029242, states[0] = 19.095175, states[40]= 0.006653
Saving checkpoint... 
Iteration: 749215732, states[0] = -94.900348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768371700, states[0] = -95.024223, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630124543266104_ORdGradInc_k_25-Pueyo_APDR-conf_701.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630124543266104_ORdGradInc_k_25-Pueyo_APDR-conf_701_0_r99551952_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630124543266104_ORdGradInc_k_25-Pueyo_APDR-conf_701_0_r99551952_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 108.999586
     * GNaL_b in INaL: 0.004800
     * Gto_b in Ito: 0.075638
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.029881
     * GKs_b in IKs: 0.001909
     * GK1_b in IK1: 0.181524
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 70.389390
     * GKb_b in IKb: 0.003725
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038558
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 768371700
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.024223 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 784078238, states[0] = -2.157967, states[40]= 0.003967
Saving checkpoint... 
Iteration: 802120418, states[0] = -40.003442, states[40]= 0.000126
Saving checkpoint... 
Iteration: 820263517, states[0] = -94.960001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834183684, states[0] = -94.842980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850455914, states[0] = -95.043766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864781246, states[0] = -94.975731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879823791, states[0] = -95.003800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897207927, states[0] = -94.887658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910943408, states[0] = -95.041695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922725364, states[0] = -94.914646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938331012, states[0] = -95.007468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956360290, states[0] = -95.020079, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630124543266104_ORdGradInc_k_25-Pueyo_APDR-conf_701.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630124543266104_ORdGradInc_k_25-Pueyo_APDR-conf_701_0_r99551952_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630124543266104_ORdGradInc_k_25-Pueyo_APDR-conf_701_0_r99551952_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 108.999586
     * GNaL_b in INaL: 0.004800
     * Gto_b in Ito: 0.075638
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.029881
     * GKs_b in IKs: 0.001909
     * GK1_b in IK1: 0.181524
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 70.389390
     * GKb_b in IKb: 0.003725
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038558
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 956360290
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.020079 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 957130997, states[0] = -50.896120, states[40]= 0.000023
Saving checkpoint... 
Iteration: 982826505, states[0] = -95.005165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012381631, states[0] = -95.027270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039406108, states[0] = -95.033944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067287682, states[0] = -94.980672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093527923, states[0] = 19.514417, states[40]= 0.006913
Saving checkpoint... 
Iteration: 1117242754, states[0] = -94.937359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142219710, states[0] = -94.906232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170885894, states[0] = -95.028460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196538633, states[0] = 15.799852, states[40]= 0.005605
Saving checkpoint... 
Iteration: 1230379413, states[0] = -95.026466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256623105, states[0] = -42.686590, states[40]= 0.000084
Saving checkpoint... 
Iteration: 1284034804, states[0] = 17.200533, states[40]= 0.005914
Saving checkpoint... 
Iteration: 1317255201, states[0] = -94.951293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344341242, states[0] = -95.012064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376500411, states[0] = -43.673124, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1414490004, states[0] = -95.047948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453837556, states[0] = -95.010322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484132984, states[0] = -53.038962, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1512551406, states[0] = -95.222093, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630124543266104_ORdGradInc_k_25-Pueyo_APDR-conf_701.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630124543266104_ORdGradInc_k_25-Pueyo_APDR-conf_701_0_r99551952_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630124543266104_ORdGradInc_k_25-Pueyo_APDR-conf_701_0_r99551952_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 108.999586
     * GNaL_b in INaL: 0.004800
     * Gto_b in Ito: 0.075638
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.029881
     * GKs_b in IKs: 0.001909
     * GK1_b in IK1: 0.181524
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 70.389390
     * GKb_b in IKb: 0.003725
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038558
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1512551406
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.222093 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading resultsTime...
Loading resultsAPD90...
Loading resultsAPD75...
Loading resultsAPD50...
Loading resultsAPD25...
Loading resultsAPD10...
Loading resultsTriangulation...
Loading resultsMaxV...
Loading resultsMinV...
Loading resultsMaxDiffV...
Loading resultsMinDiffV...
Copy resultsTime...
Copy resultsAPD90...
Copy resultsAPD75...
Copy resultsAPD50...
Copy resultsAPD25...
Copy resultsAPD10...
Copy resultsTriangulation...
Copy resultsMaxV...
Copy resultsMinV...
Copy resultsMaxDiffV...
Copy resultsMinDiffV...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1536802681, states[0] = -95.179399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1556196052, states[0] = -33.093580, states[40]= 0.000323
Saving checkpoint... 
Iteration: 1581874546, states[0] = -95.271952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1603233763, states[0] = 15.762712, states[40]= 0.006921
Saving checkpoint... 
Iteration: 1626604476, states[0] = 33.126915, states[40]= 0.117193
Saving checkpoint... 
Iteration: 1649981356, states[0] = -95.280437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1676250112, states[0] = -95.042397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1701255297, states[0] = -95.260606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1720913105, states[0] = -53.336659, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1743992107, states[0] = -29.448263, states[40]= 0.000480
Saving checkpoint... 
Iteration: 1767053494, states[0] = 5.499740, states[40]= 0.005502
Saving checkpoint... 
Iteration: 1788206484, states[0] = -95.203190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1810960553, states[0] = -95.080500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1830109446, states[0] = -31.131823, states[40]= 0.000407
Saving checkpoint... 
Iteration: 1856823688, states[0] = -95.013368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1877205924, states[0] = -94.889446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1898256288, states[0] = -94.955134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1917447249, states[0] = -95.043457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1941017797, states[0] = 22.256058, states[40]= 0.013217
Saving checkpoint... 
Iteration: 1961961095, states[0] = -95.044356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1982380160, states[0] = -95.026498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2005452848, states[0] = -95.042743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028499857, states[0] = -95.048687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2053236116, states[0] = -94.928585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2072627686, states[0] = -47.393533, states[40]= 0.000041
Saving checkpoint... 
Iteration: 2096781187, states[0] = -94.974972, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.924481
 - CaMKt in component CaMK (millimolar): 0.006702
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.585435
 - nass in component intracellular_ions (millimolar): 6.585493
 - ki in component intracellular_ions (millimolar): 145.396607
 - kss in component intracellular_ions (millimolar): 145.396589
 - cansr in component intracellular_ions (millimolar): 1.295664
 - cajsr in component intracellular_ions (millimolar): 1.258122
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003610
 - hf in component INa (dimensionless): 0.880393
 - hs in component INa (dimensionless): 0.880389
 - j in component INa (dimensionless): 0.880364
 - hsp in component INa (dimensionless): 0.726573
 - jp in component INa (dimensionless): 0.880347
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711026
 - hLp in component INaL (dimensionless): 0.454241
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.622809
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.697874
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935364
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999885
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001545
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.337113
 - xs1 in component IKs (dimensionless): 0.239460
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997331
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:31:41 (796): called boinc_finish(0)

</stderr_txt>
]]>