𝕏

Task 55431010

Name HuVeMOp_20240630122619249330_ORdGradInc_k_25-Pueyo_APDR-conf_398_0
Workunit 26321904
Created 30 Jun 2024, 10:26:54 UTC
Sent 30 Jun 2024, 12:05:17 UTC
Report deadline 3 Jul 2024, 21:41:17 UTC
Received 30 Jun 2024, 14:31:41 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241023
Run time 2 hours 25 min 57 sec
CPU time 2 hours 23 min 48 sec
Validate state Valid
Credit 59.89
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.25 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-Pueyo_APDR-conf_398.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-Pueyo_APDR-conf_398_0_r1688730668_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-Pueyo_APDR-conf_398_0_r1688730668_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.525799
     * GNaL_b in INaL: 0.007197
     * Gto_b in Ito: 0.100556
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032064
     * GKs_b in IKs: 0.001757
     * GK1_b in IK1: 0.166926
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 72.278946
     * GKb_b in IKb: 0.003868
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032510
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15113669, states[0] = -30.295109, states[40]= 0.000463
Saving checkpoint... 
Iteration: 30663024, states[0] = -88.852132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46041341, states[0] = 15.336806, states[40]= 0.004771
Saving checkpoint... 
Iteration: 61228265, states[0] = -95.015835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76462063, states[0] = -95.161323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91371434, states[0] = -95.132488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106265376, states[0] = -95.054409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121089484, states[0] = -5.529594, states[40]= 0.003192
Saving checkpoint... 
Iteration: 136702430, states[0] = -94.950510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152184351, states[0] = -94.886257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167756100, states[0] = -95.039164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183063262, states[0] = 8.021648, states[40]= 0.004642
Saving checkpoint... 
Iteration: 198290765, states[0] = -95.075917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213708882, states[0] = -94.961921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229018893, states[0] = 20.966148, states[40]= 0.009660
Saving checkpoint... 
Iteration: 244610641, states[0] = -23.321405, states[40]= 0.000823
Saving checkpoint... 
Iteration: 259891426, states[0] = -95.132618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275380595, states[0] = -95.128761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290728809, states[0] = -94.998235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305672457, states[0] = -93.717389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320226656, states[0] = -94.994555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334928346, states[0] = -95.143004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349681882, states[0] = -94.847360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364728120, states[0] = -94.997002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379576226, states[0] = 2.357874, states[40]= 0.004363
Saving checkpoint... 
Iteration: 394429912, states[0] = -95.143324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409158570, states[0] = -75.283670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423933619, states[0] = -95.144156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438754879, states[0] = -95.036647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453376493, states[0] = -95.127041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467764779, states[0] = -95.048791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482221658, states[0] = -94.985676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496601599, states[0] = -15.257839, states[40]= 0.001400
Saving checkpoint... 
Iteration: 511032000, states[0] = 18.481504, states[40]= 0.005235
Saving checkpoint... 
Iteration: 525533747, states[0] = 18.015835, states[40]= 0.005101
Saving checkpoint... 
Iteration: 540137777, states[0] = -49.204758, states[40]= 0.000035
Saving checkpoint... 
Iteration: 554567067, states[0] = 6.488426, states[40]= 0.004602
Saving checkpoint... 
Iteration: 568997415, states[0] = -95.154950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583580431, states[0] = 0.188726, states[40]= 0.004140
Saving checkpoint... 
Iteration: 598067035, states[0] = 6.501772, states[40]= 0.004603
Saving checkpoint... 
Iteration: 612466739, states[0] = -95.150475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627418027, states[0] = -95.140198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642488993, states[0] = -95.153800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657395222, states[0] = -95.133520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672338935, states[0] = -95.109422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687448410, states[0] = -95.147088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702353228, states[0] = -95.116791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717221481, states[0] = -94.985178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732097192, states[0] = -11.429115, states[40]= 0.001994
Saving checkpoint... 
Iteration: 747079247, states[0] = 0.821665, states[40]= 0.004213
Saving checkpoint... 
Iteration: 762732257, states[0] = -95.003539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778125333, states[0] = -36.664326, states[40]= 0.000228
Saving checkpoint... 
Iteration: 793537876, states[0] = 16.831318, states[40]= 0.004881
Saving checkpoint... 
Iteration: 808756219, states[0] = -95.038084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824354485, states[0] = -95.117300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839518100, states[0] = 21.045070, states[40]= 0.010612
Saving checkpoint... 
Iteration: 854811738, states[0] = -95.092021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869595378, states[0] = -9.916267, states[40]= 0.002283
Saving checkpoint... 
Iteration: 884638123, states[0] = -49.577779, states[40]= 0.000033
Saving checkpoint... 
Iteration: 899510537, states[0] = 21.537145, states[40]= 0.046057
Saving checkpoint... 
Iteration: 914420330, states[0] = -95.140576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929345839, states[0] = -95.112924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943782153, states[0] = -95.067000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958229253, states[0] = -94.998446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973228288, states[0] = -94.996816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988252710, states[0] = -95.033391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003228220, states[0] = -94.996679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018271283, states[0] = -95.055714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033466516, states[0] = -95.150118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048224417, states[0] = -94.990119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063199519, states[0] = -94.941743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078007936, states[0] = 22.231593, states[40]= 0.088251
Saving checkpoint... 
Iteration: 1093203553, states[0] = -94.950243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108338592, states[0] = -95.108899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123490210, states[0] = -95.153597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138751672, states[0] = -95.031897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154062611, states[0] = 8.287584, states[40]= 0.004646
Saving checkpoint... 
Iteration: 1169175885, states[0] = -94.494104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184661240, states[0] = -79.903599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199476055, states[0] = -95.151515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214817830, states[0] = -95.096025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230165553, states[0] = -87.425655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245653012, states[0] = -67.019566, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1260764311, states[0] = -95.047637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275738247, states[0] = -95.012583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291148668, states[0] = -61.516967, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1306395752, states[0] = -95.133197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321311842, states[0] = -95.091740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336239687, states[0] = -95.014723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351174023, states[0] = -94.169822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366138102, states[0] = -49.554736, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1381136336, states[0] = -47.662050, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1396002561, states[0] = 38.275705, states[40]= 0.134184
Saving checkpoint... 
Iteration: 1410936126, states[0] = -95.143966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426010789, states[0] = 21.509154, states[40]= 0.043287
Saving checkpoint... 
Iteration: 1441023131, states[0] = 20.396406, states[40]= 0.006873
Saving checkpoint... 
Iteration: 1456147727, states[0] = -60.391420, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1471146429, states[0] = -58.866220, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1486123975, states[0] = -35.391980, states[40]= 0.000270
Saving checkpoint... 
Iteration: 1501174710, states[0] = -95.336656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1516209041, states[0] = 22.959764, states[40]= 0.065998
Saving checkpoint... 
Iteration: 1531180502, states[0] = -95.385601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1546077542, states[0] = -95.241223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1560980551, states[0] = -12.157382, states[40]= 0.002132
Saving checkpoint... 
Iteration: 1575681159, states[0] = -12.962196, states[40]= 0.001978
Saving checkpoint... 
Iteration: 1590472800, states[0] = -95.242609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1605438711, states[0] = -84.925054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1620680636, states[0] = -12.678478, states[40]= 0.002034
Saving checkpoint... 
Iteration: 1635717087, states[0] = -52.100566, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1650796932, states[0] = -95.302490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1666087897, states[0] = -95.283311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1680985287, states[0] = -17.512540, states[40]= 0.001292
Saving checkpoint... 
Iteration: 1695556290, states[0] = -95.391351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1709957808, states[0] = -95.392962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1724475437, states[0] = -7.747234, states[40]= 0.003123
Saving checkpoint... 
Iteration: 1739310144, states[0] = -95.328018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1753886360, states[0] = -18.635952, states[40]= 0.001173
Saving checkpoint... 
Iteration: 1768311615, states[0] = -45.568539, states[40]= 0.000064
Saving checkpoint... 
Iteration: 1782700907, states[0] = -33.762398, states[40]= 0.000324
Saving checkpoint... 
Iteration: 1797171107, states[0] = -95.241928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1811902034, states[0] = -95.183456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1826592578, states[0] = -9.274156, states[40]= 0.002440
Saving checkpoint... 
Iteration: 1841121982, states[0] = -34.860067, states[40]= 0.000290
Saving checkpoint... 
Iteration: 1855663871, states[0] = -86.416191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1870408510, states[0] = -95.145406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1885001871, states[0] = 44.376602, states[40]= 0.093146
Saving checkpoint... 
Iteration: 1899387492, states[0] = -95.133604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1913970883, states[0] = -95.152477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1928435921, states[0] = -95.145003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1943300326, states[0] = -95.083366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1957972006, states[0] = -95.150875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1972721223, states[0] = -94.984100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1987511106, states[0] = 21.477006, states[40]= 0.040064
Saving checkpoint... 
Iteration: 2002596389, states[0] = -10.761529, states[40]= 0.002118
Saving checkpoint... 
Iteration: 2017735775, states[0] = -95.008222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2032877446, states[0] = -95.126199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2048090520, states[0] = -6.150043, states[40]= 0.003063
Saving checkpoint... 
Iteration: 2063361687, states[0] = -95.119625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2078236366, states[0] = -95.009007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2092625973, states[0] = -37.268611, states[40]= 0.000209
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.029914
 - CaMKt in component CaMK (millimolar): 0.007426
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.520157
 - nass in component intracellular_ions (millimolar): 6.520220
 - ki in component intracellular_ions (millimolar): 145.451965
 - kss in component intracellular_ions (millimolar): 145.451944
 - cansr in component intracellular_ions (millimolar): 1.330946
 - cajsr in component intracellular_ions (millimolar): 1.291637
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003572
 - hf in component INa (dimensionless): 0.882205
 - hs in component INa (dimensionless): 0.882200
 - j in component INa (dimensionless): 0.882171
 - hsp in component INa (dimensionless): 0.729996
 - jp in component INa (dimensionless): 0.882151
 - mL in component INaL (dimensionless): 0.000048
 - hL in component INaL (dimensionless): 0.711514
 - hLp in component INaL (dimensionless): 0.450656
 - a in component Ito (dimensionless): 0.000618
 - iF in component Ito (dimensionless): 0.999873
 - iS in component Ito (dimensionless): 0.614364
 - ap in component Ito (dimensionless): 0.000315
 - iFp in component Ito (dimensionless): 0.999873
 - iSp in component Ito (dimensionless): 0.688328
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.931056
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999869
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001666
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329329
 - xs1 in component IKs (dimensionless): 0.254280
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997303
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:31:24 (595807): called boinc_finish(0)

</stderr_txt>
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