𝕏

Task 55430892

Name HuVeMOp_20240630122619249330_ORdGradInc_k_25-Pueyo_APDR-conf_982_0
Workunit 26321845
Created 30 Jun 2024, 10:26:54 UTC
Sent 30 Jun 2024, 12:04:27 UTC
Report deadline 3 Jul 2024, 21:40:27 UTC
Received 1 Jul 2024, 16:01:39 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 240844
Run time 1 hours 7 min 45 sec
CPU time 59 min 23 sec
Validate state Valid
Credit 61.40
Device peak FLOPS 5.36 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.25 MB
Peak swap size 5.32 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-Pueyo_APDR-conf_982.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-Pueyo_APDR-conf_982_0_r264103365_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-Pueyo_APDR-conf_982_0_r264103365_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 113.896738
     * GNaL_b in INaL: 0.005529
     * Gto_b in Ito: 0.080630
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032395
     * GKs_b in IKs: 0.002121
     * GK1_b in IK1: 0.146977
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 73.398620
     * GKb_b in IKb: 0.003859
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.020081
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11839651, states[0] = -94.910771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29101294, states[0] = -27.322567, states[40]= 0.000570
Saving checkpoint... 
Iteration: 46715474, states[0] = -94.682939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62440003, states[0] = -94.848619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79734964, states[0] = -94.694564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97233807, states[0] = -94.687150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115079798, states[0] = -4.896074, states[40]= 0.003484
Saving checkpoint... 
Iteration: 132716056, states[0] = -94.649570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150338040, states[0] = -94.789463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167585282, states[0] = -9.196764, states[40]= 0.002551
Saving checkpoint... 
Iteration: 185790741, states[0] = -94.752739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203956150, states[0] = -94.830187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221977823, states[0] = -94.833829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240011464, states[0] = 23.089719, states[40]= 0.038970
Saving checkpoint... 
Iteration: 257699206, states[0] = -94.611387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275605929, states[0] = -28.918361, states[40]= 0.000504
Saving checkpoint... 
Iteration: 292416417, states[0] = -94.820531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308442162, states[0] = -94.826941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326517212, states[0] = 21.756347, states[40]= 0.013922
Saving checkpoint... 
Iteration: 344875467, states[0] = -94.806429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362262506, states[0] = -94.721161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379234208, states[0] = -94.679852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391079059, states[0] = -4.217307, states[40]= 0.003619
Saving checkpoint... 
Iteration: 408209273, states[0] = -94.632961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424993403, states[0] = -94.835797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443034652, states[0] = 16.691168, states[40]= 0.005830
Saving checkpoint... 
Iteration: 461290609, states[0] = -94.751912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479475013, states[0] = -94.833049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498801728, states[0] = -94.761859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517942409, states[0] = -94.826856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536949580, states[0] = -94.828370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556355214, states[0] = -94.797052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575205564, states[0] = -94.625030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594442008, states[0] = -94.826722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613862971, states[0] = -94.800771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633041258, states[0] = 14.221253, states[40]= 0.005389
Saving checkpoint... 
Iteration: 651399439, states[0] = -94.815117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670253209, states[0] = -94.708679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689564441, states[0] = 4.293997, states[40]= 0.004773


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-Pueyo_APDR-conf_982.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-Pueyo_APDR-conf_982_0_r264103365_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-Pueyo_APDR-conf_982_0_r264103365_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 113.896738
     * GNaL_b in INaL: 0.005529
     * Gto_b in Ito: 0.080630
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032395
     * GKs_b in IKs: 0.002121
     * GK1_b in IK1: 0.146977
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 73.398620
     * GKb_b in IKb: 0.003859
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.020081
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 689564441
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 4.293997 (After loading)
 - states[40]: 0.004773 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 708023630, states[0] = 20.196545, states[40]= 0.008002
Saving checkpoint... 
Iteration: 726814411, states[0] = -94.771819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745754115, states[0] = -94.709883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765620861, states[0] = -43.697911, states[40]= 0.000072
Saving checkpoint... 
Iteration: 785404221, states[0] = -94.816579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804700570, states[0] = -94.614026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823830948, states[0] = -94.783162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843089458, states[0] = -12.954776, states[40]= 0.001814
Saving checkpoint... 
Iteration: 862214655, states[0] = -94.643665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881249000, states[0] = -94.702594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900293204, states[0] = -94.754075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919256323, states[0] = -94.712776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938143993, states[0] = -69.058923, states[40]= 0.000001
Saving checkpoint... 
Iteration: 957230975, states[0] = -94.674003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976372221, states[0] = -94.804681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995428889, states[0] = -94.823395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014577434, states[0] = -3.083170, states[40]= 0.003838
Saving checkpoint... 
Iteration: 1033396039, states[0] = -94.813747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052144491, states[0] = -69.688189, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1071236520, states[0] = -94.683259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090341436, states[0] = -94.789333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109263969, states[0] = -94.722538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128666603, states[0] = -93.851988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142404385, states[0] = -94.816416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161796921, states[0] = -94.757285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181005387, states[0] = 28.501418, states[40]= 0.137864
Saving checkpoint... 
Iteration: 1200233262, states[0] = -94.677762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219607716, states[0] = -30.653445, states[40]= 0.000423
Saving checkpoint... 
Iteration: 1238875863, states[0] = -94.806051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258176228, states[0] = -94.510775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277383950, states[0] = -94.809237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292772351, states[0] = -94.732406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311931356, states[0] = -94.823815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331256584, states[0] = -94.712877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344527592, states[0] = 19.048019, states[40]= 0.006821
Saving checkpoint... 
Iteration: 1363472735, states[0] = -94.832146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382818364, states[0] = -94.774320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402453681, states[0] = -94.828677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421786733, states[0] = -94.747587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441140819, states[0] = -65.220494, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1460278838, states[0] = -94.739464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473323369, states[0] = -94.777775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492696661, states[0] = -94.604827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1512020071, states[0] = 21.162157, states[40]= 0.011889
Saving checkpoint... 
Iteration: 1531212306, states[0] = 23.569166, states[40]= 0.034134
Saving checkpoint... 
Iteration: 1550896384, states[0] = -95.005076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1570406023, states[0] = -95.032921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1589780801, states[0] = -19.735244, states[40]= 0.001076
Saving checkpoint... 
Iteration: 1608829788, states[0] = -95.080121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628426657, states[0] = 18.204453, states[40]= 0.008132
Saving checkpoint... 
Iteration: 1647715668, states[0] = -60.158756, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1666743821, states[0] = -95.101717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1685704185, states[0] = 33.570416, states[40]= 0.122908
Saving checkpoint... 
Iteration: 1704605983, states[0] = 28.513299, states[40]= 0.113798
Saving checkpoint... 
Iteration: 1723544294, states[0] = 9.704234, states[40]= 0.005956
Saving checkpoint... 
Iteration: 1736458367, states[0] = 1.343028, states[40]= 0.005064
Saving checkpoint... 
Iteration: 1755568878, states[0] = -95.130178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1774706768, states[0] = -95.043209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1793952341, states[0] = -95.112434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1812622037, states[0] = -48.142386, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1831028439, states[0] = 18.477358, states[40]= 0.006613
Saving checkpoint... 
Iteration: 1849775595, states[0] = -94.754714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1868478483, states[0] = -94.843410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1886940358, states[0] = -94.831649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1905439264, states[0] = -94.828774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1918924894, states[0] = -94.824108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1937350650, states[0] = -94.795174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1955441676, states[0] = -94.826560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1973362226, states[0] = -94.800011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1991519840, states[0] = 21.158567, states[40]= 0.010412
Saving checkpoint... 
Iteration: 2009954432, states[0] = -94.828562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028106934, states[0] = -29.896710, states[40]= 0.000458
Saving checkpoint... 
Iteration: 2047136724, states[0] = -60.585148, states[40]= 0.000004
Saving checkpoint... 
Iteration: 2066179835, states[0] = -94.548821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2085499613, states[0] = -94.835577, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.711487
 - CaMKt in component CaMK (millimolar): 0.006823
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.540265
 - nass in component intracellular_ions (millimolar): 6.540324
 - ki in component intracellular_ions (millimolar): 145.438484
 - kss in component intracellular_ions (millimolar): 145.438465
 - cansr in component intracellular_ions (millimolar): 1.308649
 - cajsr in component intracellular_ions (millimolar): 1.271324
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003689
 - hf in component INa (dimensionless): 0.876658
 - hs in component INa (dimensionless): 0.876653
 - j in component INa (dimensionless): 0.876621
 - hsp in component INa (dimensionless): 0.719559
 - jp in component INa (dimensionless): 0.876599
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.705463
 - hLp in component INaL (dimensionless): 0.448069
 - a in component Ito (dimensionless): 0.000632
 - iF in component Ito (dimensionless): 0.999865
 - iS in component Ito (dimensionless): 0.623900
 - ap in component Ito (dimensionless): 0.000322
 - iFp in component Ito (dimensionless): 0.999865
 - iSp in component Ito (dimensionless): 0.698994
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.938242
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999896
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001595
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.336479
 - xs1 in component IKs (dimensionless): 0.233543
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997387
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:36:44 (27448): called boinc_finish(0)

</stderr_txt>
]]>