𝕏

Task 55430884

Name HuVeMOp_20240630122619249330_ORdGradInc_k_25-Pueyo_APDR-conf_581_0
Workunit 26321841
Created 30 Jun 2024, 10:26:54 UTC
Sent 30 Jun 2024, 12:05:25 UTC
Report deadline 3 Jul 2024, 21:41:25 UTC
Received 30 Jun 2024, 18:05:38 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241136
Run time 1 hours 36 min 28 sec
CPU time 1 hours 35 min 21 sec
Validate state Valid
Credit 62.02
Device peak FLOPS 6.42 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-Pueyo_APDR-conf_581.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-Pueyo_APDR-conf_581_0_r340815376_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-Pueyo_APDR-conf_581_0_r340815376_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 113.646992
     * GNaL_b in INaL: 0.004825
     * Gto_b in Ito: 0.081128
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032896
     * GKs_b in IKs: 0.001796
     * GK1_b in IK1: 0.158346
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 66.332817
     * GKb_b in IKb: 0.003740
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.048964
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8790882, states[0] = -95.096452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22045419, states[0] = 11.162145, states[40]= 0.005203
Saving checkpoint... 
Iteration: 35197764, states[0] = -94.925692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49020173, states[0] = 20.448267, states[40]= 0.010353
Saving checkpoint... 
Iteration: 58035063, states[0] = 15.790346, states[40]= 0.005833
Saving checkpoint... 
Iteration: 71403844, states[0] = -95.073457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84649232, states[0] = -85.855727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97849769, states[0] = -95.048833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110957297, states[0] = -95.076278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124150455, states[0] = -87.121832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137625501, states[0] = -52.520952, states[40]= 0.000016
Saving checkpoint... 
Iteration: 150804668, states[0] = -95.019966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164371143, states[0] = -95.052388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177796973, states[0] = -95.013904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191161023, states[0] = -94.329977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204437103, states[0] = -95.069139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217784961, states[0] = -95.004215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230765051, states[0] = -94.986053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244257205, states[0] = -94.977791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257305253, states[0] = -95.019105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270655375, states[0] = -92.292687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284029905, states[0] = 17.830470, states[40]= 0.006499
Saving checkpoint... 
Iteration: 293254303, states[0] = -94.974486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306592470, states[0] = -17.783989, states[40]= 0.001140
Saving checkpoint... 
Iteration: 320041852, states[0] = 13.426404, states[40]= 0.005359
Saving checkpoint... 
Iteration: 333197657, states[0] = -94.888991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346912949, states[0] = -95.063638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360269029, states[0] = -94.989772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373621707, states[0] = -48.146478, states[40]= 0.000033
Saving checkpoint... 
Iteration: 387295770, states[0] = -95.012328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400006219, states[0] = 26.591504, states[40]= 0.117043
Saving checkpoint... 
Iteration: 413267218, states[0] = -94.987977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426784189, states[0] = -95.003279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440113582, states[0] = -39.377741, states[40]= 0.000126
Saving checkpoint... 
Iteration: 453747458, states[0] = -94.966415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467072996, states[0] = -1.221357, states[40]= 0.004116
Saving checkpoint... 
Iteration: 480297952, states[0] = -95.013863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493429444, states[0] = -95.067201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506993583, states[0] = -95.077057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520257432, states[0] = -94.977800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529024213, states[0] = 19.588396, states[40]= 0.007973
Saving checkpoint... 
Iteration: 542221253, states[0] = -94.930173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555486041, states[0] = -95.076157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568254160, states[0] = -94.974157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581217834, states[0] = -94.924696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594735577, states[0] = -94.951112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608042083, states[0] = 13.335022, states[40]= 0.005347
Saving checkpoint... 
Iteration: 621845300, states[0] = -95.040959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635387911, states[0] = -95.056757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647827865, states[0] = -95.032373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661412720, states[0] = -95.063412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674958362, states[0] = -95.072288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688567571, states[0] = 1.912302, states[40]= 0.004520
Saving checkpoint... 
Iteration: 702014750, states[0] = 21.911891, states[40]= 0.020772
Saving checkpoint... 
Iteration: 715366778, states[0] = -95.049672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728336365, states[0] = -95.036690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741809275, states[0] = -95.021420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755433746, states[0] = -95.067925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768280351, states[0] = -94.999864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781922469, states[0] = -95.065575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795137044, states[0] = -66.023591, states[40]= 0.000002
Saving checkpoint... 
Iteration: 808466499, states[0] = -95.073441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821404885, states[0] = -95.061386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834873518, states[0] = -95.052009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848137917, states[0] = -67.162841, states[40]= 0.000001
Saving checkpoint... 
Iteration: 861679969, states[0] = -94.851469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875060430, states[0] = 5.485245, states[40]= 0.004812
Saving checkpoint... 
Iteration: 887926193, states[0] = -95.066318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901314475, states[0] = -95.024589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914508215, states[0] = 24.312450, states[40]= 0.079831
Saving checkpoint... 
Iteration: 928153285, states[0] = -90.495024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937903639, states[0] = -95.061002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951329013, states[0] = -95.032822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964387692, states[0] = -95.056517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977454757, states[0] = -95.071556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991112137, states[0] = -37.865746, states[40]= 0.000156
Saving checkpoint... 
Iteration: 1004654190, states[0] = -91.366631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018286089, states[0] = -95.004519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031440802, states[0] = -95.069120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045272325, states[0] = -94.992531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058626010, states[0] = -52.956536, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1071793636, states[0] = -95.010379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085088637, states[0] = -13.952534, states[40]= 0.001635
Saving checkpoint... 
Iteration: 1098653619, states[0] = -90.833981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107499160, states[0] = -95.077348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115504577, states[0] = 30.581076, states[40]= 0.137443
Saving checkpoint... 
Iteration: 1128615256, states[0] = -41.144954, states[40]= 0.000097
Saving checkpoint... 
Iteration: 1141888692, states[0] = -95.056723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155243964, states[0] = -94.961754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169013410, states[0] = 22.224394, states[40]= 0.026474
Saving checkpoint... 
Iteration: 1182115058, states[0] = -40.934836, states[40]= 0.000100
Saving checkpoint... 
Iteration: 1195235341, states[0] = -94.950471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209001647, states[0] = 48.871882, states[40]= 0.055792
Saving checkpoint... 
Iteration: 1221852027, states[0] = -95.043582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235557034, states[0] = 7.045468, states[40]= 0.004903
Saving checkpoint... 
Iteration: 1248694499, states[0] = -94.882340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262057861, states[0] = 6.671758, states[40]= 0.004883
Saving checkpoint... 
Iteration: 1275502819, states[0] = 39.649876, states[40]= 0.107101
Saving checkpoint... 
Iteration: 1288861706, states[0] = -95.047458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302256233, states[0] = -94.976073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315488146, states[0] = -95.076006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328966330, states[0] = -95.073142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342246435, states[0] = -94.964703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355844894, states[0] = -95.040387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369312165, states[0] = -95.022917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382755009, states[0] = -94.974675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396192686, states[0] = -94.878664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409538610, states[0] = 14.693202, states[40]= 0.005548
Saving checkpoint... 
Iteration: 1423064188, states[0] = 3.664909, states[40]= 0.004682
Saving checkpoint... 
Iteration: 1436353601, states[0] = -95.044129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449690812, states[0] = -94.874867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463358069, states[0] = -95.045938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476746479, states[0] = -94.964685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490234490, states[0] = -94.949148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1503588267, states[0] = -95.301325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1516900219, states[0] = -42.132260, states[40]= 0.000086
Saving checkpoint... 
Iteration: 1530088328, states[0] = -29.131989, states[40]= 0.000463
Saving checkpoint... 
Iteration: 1543448955, states[0] = -95.309091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1556460464, states[0] = -0.702464, states[40]= 0.004689
Saving checkpoint... 
Iteration: 1569642866, states[0] = 10.019225, states[40]= 0.005982
Saving checkpoint... 
Iteration: 1578142087, states[0] = -94.899911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1591292955, states[0] = -35.995778, states[40]= 0.000207
Saving checkpoint... 
Iteration: 1604478124, states[0] = -18.755187, states[40]= 0.001158
Saving checkpoint... 
Iteration: 1617368866, states[0] = -8.447447, states[40]= 0.003019
Saving checkpoint... 
Iteration: 1630879105, states[0] = -19.990404, states[40]= 0.001035
Saving checkpoint... 
Iteration: 1644417407, states[0] = -67.278163, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1657026693, states[0] = -82.942929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1670107192, states[0] = 26.371065, states[40]= 0.091512
Saving checkpoint... 
Iteration: 1678883547, states[0] = -25.241969, states[40]= 0.000662
Saving checkpoint... 
Iteration: 1687700285, states[0] = -95.264554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1701214125, states[0] = -95.286667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1714415483, states[0] = -95.288693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1727581606, states[0] = -95.229102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1740577574, states[0] = -95.353918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1753904512, states[0] = -50.294223, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1767235616, states[0] = -95.314902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1780777722, states[0] = -95.354029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1793750820, states[0] = 5.351448, states[40]= 0.005481
Saving checkpoint... 
Iteration: 1802690003, states[0] = -94.927665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1816097172, states[0] = -25.415406, states[40]= 0.000637
Saving checkpoint... 
Iteration: 1828204999, states[0] = -94.934938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1841673849, states[0] = -94.855996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1854706473, states[0] = -94.920365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1868041744, states[0] = 13.309880, states[40]= 0.005365
Saving checkpoint... 
Iteration: 1876703620, states[0] = -94.907793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1890270320, states[0] = -94.995788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1903796815, states[0] = -95.016060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1916530014, states[0] = 17.763066, states[40]= 0.006479
Saving checkpoint... 
Iteration: 1929931615, states[0] = -95.068638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1943429971, states[0] = -95.067727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1956932648, states[0] = -95.067867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1970190654, states[0] = -94.874818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1983444361, states[0] = -95.069613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1996682607, states[0] = -94.857413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2009377194, states[0] = -95.052780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022558939, states[0] = 6.176225, states[40]= 0.004854
Saving checkpoint... 
Iteration: 2035822133, states[0] = -95.028532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2049243922, states[0] = -94.961245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2062594291, states[0] = -19.628298, states[40]= 0.000974
Saving checkpoint... 
Iteration: 2071590385, states[0] = -15.687605, states[40]= 0.001384
Saving checkpoint... 
Iteration: 2085118106, states[0] = -44.201867, states[40]= 0.000061
Saving checkpoint... 
Iteration: 2098154610, states[0] = -91.720323, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.952758
 - CaMKt in component CaMK (millimolar): 0.006472
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.636523
 - nass in component intracellular_ions (millimolar): 6.636582
 - ki in component intracellular_ions (millimolar): 145.348051
 - kss in component intracellular_ions (millimolar): 145.348032
 - cansr in component intracellular_ions (millimolar): 1.284399
 - cajsr in component intracellular_ions (millimolar): 1.247699
 - cai in component intracellular_ions (millimolar): 0.000073
 - m in component INa (dimensionless): 0.003600
 - hf in component INa (dimensionless): 0.880881
 - hs in component INa (dimensionless): 0.880877
 - j in component INa (dimensionless): 0.880851
 - hsp in component INa (dimensionless): 0.727494
 - jp in component INa (dimensionless): 0.880834
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.713073
 - hLp in component INaL (dimensionless): 0.459043
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.629712
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.706294
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.940565
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999903
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001500
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.326448
 - xs1 in component IKs (dimensionless): 0.228821
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997324
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
14:00:54 (297516): called boinc_finish(0)

</stderr_txt>
]]>


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