𝕏

Task 55430768

Name HuVeMOp_20240630122619249330_ORdGradInc_k_25-Pueyo_APDR-conf_458_1
Workunit 26321783
Created 30 Jun 2024, 10:26:48 UTC
Sent 30 Jun 2024, 12:05:17 UTC
Report deadline 3 Jul 2024, 21:41:17 UTC
Received 30 Jun 2024, 14:31:41 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241023
Run time 2 hours 25 min 55 sec
CPU time 2 hours 23 min 43 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.25 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-Pueyo_APDR-conf_458.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-Pueyo_APDR-conf_458_1_r879203683_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-Pueyo_APDR-conf_458_1_r879203683_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 95.276105
     * GNaL_b in INaL: 0.005031
     * Gto_b in Ito: 0.098638
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030739
     * GKs_b in IKs: 0.001872
     * GK1_b in IK1: 0.166252
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 74.598325
     * GKb_b in IKb: 0.003683
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.026521
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15012882, states[0] = 20.298781, states[40]= 0.026002
Saving checkpoint... 
Iteration: 30613739, states[0] = -32.147263, states[40]= 0.000376
Saving checkpoint... 
Iteration: 46225413, states[0] = -94.894326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61490002, states[0] = -95.043202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76510408, states[0] = 21.131221, states[40]= 0.046697
Saving checkpoint... 
Iteration: 91459261, states[0] = -95.025979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106286020, states[0] = -94.944231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121297977, states[0] = -94.952904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136783831, states[0] = -94.938917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152169014, states[0] = -92.505295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167380547, states[0] = -94.997613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182612441, states[0] = -27.896615, states[40]= 0.000588
Saving checkpoint... 
Iteration: 197729488, states[0] = -94.866988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213259412, states[0] = -94.910168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228461931, states[0] = -95.018255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243968689, states[0] = -95.019345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259301074, states[0] = -94.952027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274758653, states[0] = -94.908996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290002558, states[0] = 37.601060, states[40]= 0.137276
Saving checkpoint... 
Iteration: 304770662, states[0] = -94.923070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319643213, states[0] = -57.784715, states[40]= 0.000008
Saving checkpoint... 
Iteration: 334343637, states[0] = -94.980076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349068775, states[0] = 4.466242, states[40]= 0.004515
Saving checkpoint... 
Iteration: 363918554, states[0] = -95.008625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378819465, states[0] = -94.965507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393774335, states[0] = -94.926970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408521007, states[0] = 20.123794, states[40]= 0.007912
Saving checkpoint... 
Iteration: 423361896, states[0] = -94.988931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438078724, states[0] = -0.483625, states[40]= 0.004060
Saving checkpoint... 
Iteration: 452705909, states[0] = -94.822633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467063463, states[0] = 6.742094, states[40]= 0.004610
Saving checkpoint... 
Iteration: 481445275, states[0] = -95.014760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495879617, states[0] = -94.996175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510261442, states[0] = -94.912216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524773183, states[0] = -94.925636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539169236, states[0] = -92.578996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553562762, states[0] = 7.028890, states[40]= 0.004619
Saving checkpoint... 
Iteration: 568049166, states[0] = 12.153016, states[40]= 0.004687
Saving checkpoint... 
Iteration: 582712190, states[0] = -94.835048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597266296, states[0] = -94.917899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611646468, states[0] = -61.352318, states[40]= 0.000004
Saving checkpoint... 
Iteration: 626557788, states[0] = 8.990111, states[40]= 0.004655
Saving checkpoint... 
Iteration: 641639346, states[0] = -53.705590, states[40]= 0.000015
Saving checkpoint... 
Iteration: 656486014, states[0] = -95.021587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671519172, states[0] = 20.384987, states[40]= 0.009346
Saving checkpoint... 
Iteration: 686533406, states[0] = 17.296450, states[40]= 0.005154
Saving checkpoint... 
Iteration: 701599164, states[0] = -15.850865, states[40]= 0.001327
Saving checkpoint... 
Iteration: 716362349, states[0] = -94.988909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731299370, states[0] = -94.950218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746228919, states[0] = -94.865267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761467550, states[0] = -95.018677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776934011, states[0] = -95.012095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792211757, states[0] = -94.834042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807615145, states[0] = -30.322583, states[40]= 0.000469
Saving checkpoint... 
Iteration: 823115603, states[0] = -30.739810, states[40]= 0.000449
Saving checkpoint... 
Iteration: 838638617, states[0] = -52.949361, states[40]= 0.000018
Saving checkpoint... 
Iteration: 853608738, states[0] = -24.513712, states[40]= 0.000745
Saving checkpoint... 
Iteration: 868367953, states[0] = -94.991224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883365989, states[0] = -94.990375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898344136, states[0] = -94.979903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913089872, states[0] = -7.901147, states[40]= 0.002704
Saving checkpoint... 
Iteration: 928049934, states[0] = 11.881041, states[40]= 0.004683
Saving checkpoint... 
Iteration: 942565972, states[0] = 5.691371, states[40]= 0.004574
Saving checkpoint... 
Iteration: 957085966, states[0] = -5.008174, states[40]= 0.003300
Saving checkpoint... 
Iteration: 972167840, states[0] = -91.555312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987182901, states[0] = -94.742238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002142657, states[0] = -57.188435, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1017135379, states[0] = -49.628293, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1032239272, states[0] = -94.881611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047163383, states[0] = -85.909215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062072398, states[0] = 2.788130, states[40]= 0.004402
Saving checkpoint... 
Iteration: 1076876034, states[0] = -94.994351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092140509, states[0] = -54.918614, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1107230885, states[0] = -94.868263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122521005, states[0] = 20.124272, states[40]= 0.007913
Saving checkpoint... 
Iteration: 1137827678, states[0] = -94.970250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153238859, states[0] = -94.880889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168468105, states[0] = -95.018458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183929984, states[0] = -95.010849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199333486, states[0] = -94.973720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214261387, states[0] = -94.911608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229879326, states[0] = -94.995503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245276582, states[0] = -94.928679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260355415, states[0] = -94.985298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275410375, states[0] = -95.005690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290576791, states[0] = 0.571123, states[40]= 0.004189
Saving checkpoint... 
Iteration: 1305923443, states[0] = -95.009160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320847210, states[0] = -94.981187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335660836, states[0] = -81.563400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350689371, states[0] = -94.782977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365758319, states[0] = -94.907705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380810914, states[0] = -94.958712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395758144, states[0] = -94.907462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410724512, states[0] = -94.857192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425793146, states[0] = -94.944386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440857059, states[0] = -94.985936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455830093, states[0] = -94.971493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470665968, states[0] = -89.619522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485758367, states[0] = -94.907673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1500808823, states[0] = -95.120184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1515804534, states[0] = -95.143403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1530687452, states[0] = -20.666531, states[40]= 0.000982
Saving checkpoint... 
Iteration: 1545600441, states[0] = -39.448874, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1560523517, states[0] = -95.206645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1575248191, states[0] = -95.243555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1590102413, states[0] = -37.705912, states[40]= 0.000186
Saving checkpoint... 
Iteration: 1605098904, states[0] = -34.051357, states[40]= 0.000298
Saving checkpoint... 
Iteration: 1620505942, states[0] = -95.186023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1635614969, states[0] = 21.101923, states[40]= 0.018690
Saving checkpoint... 
Iteration: 1650758857, states[0] = -95.056913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1665968815, states[0] = -3.737629, states[40]= 0.004024
Saving checkpoint... 
Iteration: 1680884577, states[0] = -95.284345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1695569546, states[0] = -95.271718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1710132089, states[0] = -74.817288, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1724637911, states[0] = -95.237167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1739381996, states[0] = -95.282413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1753890436, states[0] = -25.231294, states[40]= 0.000704
Saving checkpoint... 
Iteration: 1768348420, states[0] = -94.501414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1782728006, states[0] = -68.443753, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1797254188, states[0] = -95.256437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1812081620, states[0] = -3.958660, states[40]= 0.003573
Saving checkpoint... 
Iteration: 1826758136, states[0] = -94.938129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1841171750, states[0] = -94.126813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1855786998, states[0] = -94.951545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1870405006, states[0] = -95.011937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1885105720, states[0] = -22.084501, states[40]= 0.000853
Saving checkpoint... 
Iteration: 1899533621, states[0] = 17.191299, states[40]= 0.005136
Saving checkpoint... 
Iteration: 1914095065, states[0] = -12.325465, states[40]= 0.001841
Saving checkpoint... 
Iteration: 1928546869, states[0] = 12.934512, states[40]= 0.004705
Saving checkpoint... 
Iteration: 1943431325, states[0] = -95.011435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1958010292, states[0] = 21.223809, states[40]= 0.048113
Saving checkpoint... 
Iteration: 1972741252, states[0] = -94.884189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1987551655, states[0] = 11.261262, states[40]= 0.004676
Saving checkpoint... 
Iteration: 2002821692, states[0] = -94.965833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2018010013, states[0] = 21.274597, states[40]= 0.051568
Saving checkpoint... 
Iteration: 2033146991, states[0] = -61.946415, states[40]= 0.000004
Saving checkpoint... 
Iteration: 2048364463, states[0] = -94.988790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2063512528, states[0] = 20.986259, states[40]= 0.028270
Saving checkpoint... 
Iteration: 2078403335, states[0] = -95.002956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2092786187, states[0] = -94.937480, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.898136
 - CaMKt in component CaMK (millimolar): 0.007304
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.468633
 - nass in component intracellular_ions (millimolar): 6.468693
 - ki in component intracellular_ions (millimolar): 145.504570
 - kss in component intracellular_ions (millimolar): 145.504551
 - cansr in component intracellular_ions (millimolar): 1.325940
 - cajsr in component intracellular_ions (millimolar): 1.287129
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003620
 - hf in component INa (dimensionless): 0.879936
 - hs in component INa (dimensionless): 0.879931
 - j in component INa (dimensionless): 0.879901
 - hsp in component INa (dimensionless): 0.725707
 - jp in component INa (dimensionless): 0.879880
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708477
 - hLp in component INaL (dimensionless): 0.447963
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.616168
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.690493
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935020
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999881
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001644
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.321196
 - xs1 in component IKs (dimensionless): 0.246668
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997338
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:31:18 (595799): called boinc_finish(0)

</stderr_txt>
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