𝕏

Task 55430507

Name HuVeMOp_20240630122619249330_ORdGradInc_k_25-Drouin_ENDO_6000-conf_831_1
Workunit 26321653
Created 30 Jun 2024, 10:26:38 UTC
Sent 30 Jun 2024, 12:05:46 UTC
Report deadline 3 Jul 2024, 12:05:46 UTC
Received 1 Jul 2024, 19:22:53 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 215321
Run time 3 hours 0 min 4 sec
CPU time 56 min 19 sec
Validate state Valid
Credit 58.67
Device peak FLOPS 4.81 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.57 MB
Peak swap size 5.25 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.20</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-Drouin_ENDO_6000-conf_831.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-Drouin_ENDO_6000-conf_831_1_r448198937_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-Drouin_ENDO_6000-conf_831_1_r448198937_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.442733
     * GNaL_b in INaL: 0.005289
     * Gto_b in Ito: 0.089998
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032330
     * GKs_b in IKs: 0.001768
     * GK1_b in IK1: 0.146375
     * Gncx_b in INaCa_i: 0.000958
     * Pnak_b in INaK: 66.960368
     * GKb_b in IKb: 0.003722
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025838
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 25346987, states[0] = -93.558756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50690603, states[0] = -93.497022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77042582, states[0] = -93.503950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103193202, states[0] = -93.530693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128871541, states[0] = -93.498253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154792124, states[0] = -93.513063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180755269, states[0] = -93.550615, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-Drouin_ENDO_6000-conf_831.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-Drouin_ENDO_6000-conf_831_1_r448198937_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-Drouin_ENDO_6000-conf_831_1_r448198937_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.442733
     * GNaL_b in INaL: 0.005289
     * Gto_b in Ito: 0.089998
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032330
     * GKs_b in IKs: 0.001768
     * GK1_b in IK1: 0.146375
     * Gncx_b in INaCa_i: 0.000958
     * Pnak_b in INaK: 66.960368
     * GKb_b in IKb: 0.003722
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025838
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 180755269
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.550615 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 187756474, states[0] = -93.514260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207975092, states[0] = -93.543728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227608222, states[0] = -93.501617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240868440, states[0] = -93.548461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262626177, states[0] = -93.517689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271242296, states[0] = -93.531071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281467954, states[0] = -93.502991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301256288, states[0] = -93.530434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319673580, states[0] = -93.516357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333289316, states[0] = -93.132047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359725952, states[0] = -93.500452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373065056, states[0] = -93.539184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391524219, states[0] = -93.520467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406128619, states[0] = -93.536039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426173336, states[0] = -49.396320, states[40]= 0.000263
Saving checkpoint... 
Iteration: 447551903, states[0] = -93.526626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460791541, states[0] = -93.513270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471536423, states[0] = -93.521221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491735979, states[0] = -93.500133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507970651, states[0] = -93.543576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517421539, states[0] = -93.523636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529647846, states[0] = -93.516660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538293667, states[0] = -93.528458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557472987, states[0] = -93.502460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567163088, states[0] = -41.640029, states[40]= 0.000740
Saving checkpoint... 
Iteration: 582370873, states[0] = -93.366790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598063075, states[0] = -93.538876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619819847, states[0] = -93.512357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626550197, states[0] = -93.501549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626758573, states[0] = -93.499705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627766667, states[0] = -93.550169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628029186, states[0] = -93.540494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628273749, states[0] = -93.529119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628532225, states[0] = -93.519791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628791358, states[0] = -93.512969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629053868, states[0] = -93.507902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629314451, states[0] = -93.504151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629579754, states[0] = -93.501258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629838424, states[0] = -93.499086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630651301, states[0] = -93.545589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635520952, states[0] = -93.501823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635773955, states[0] = -93.499567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636008136, states[0] = 29.520264, states[40]= 0.117385
Saving checkpoint... 
Iteration: 636267242, states[0] = -93.029853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636495630, states[0] = -93.502091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640220000, states[0] = -93.531408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640597530, states[0] = -93.517841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640855248, states[0] = -93.511568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641282921, states[0] = -93.504529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646140079, states[0] = -93.535060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650939067, states[0] = -93.498336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655819280, states[0] = -93.512304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660664526, states[0] = -93.546733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665485579, states[0] = -93.502131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670550992, states[0] = -93.519145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675549159, states[0] = -93.525324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675937555, states[0] = -93.544832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676196543, states[0] = -93.532391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676463786, states[0] = -93.521898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676719159, states[0] = -93.514572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676966830, states[0] = -93.509328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677216561, states[0] = -93.505350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677468207, states[0] = -93.502292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677726411, states[0] = -93.499873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678299358, states[0] = -93.171520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678546656, states[0] = -93.524485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680677714, states[0] = -93.500278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682630402, states[0] = -93.516852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682860198, states[0] = -93.511389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683103495, states[0] = -93.507004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683365836, states[0] = -93.503429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684559737, states[0] = -93.528602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687137800, states[0] = -22.790098, states[40]= 0.002045
Saving checkpoint... 
Iteration: 688425158, states[0] = -93.523199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688688598, states[0] = -93.515311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688947813, states[0] = -93.509657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689194676, states[0] = -93.505635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689436800, states[0] = -93.502610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690575409, states[0] = -93.532848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690801169, states[0] = -93.549661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691037937, states[0] = -93.539948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691299030, states[0] = -93.527962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691565111, states[0] = -93.518686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692037552, states[0] = -93.508060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696950748, states[0] = -93.544180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697631007, states[0] = -93.516808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702069616, states[0] = 17.530309, states[40]= 0.000770
Saving checkpoint... 
Iteration: 705978166, states[0] = -93.542855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706236314, states[0] = -93.530573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706482183, states[0] = -93.521236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706725288, states[0] = -93.514368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706980601, states[0] = -93.509024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707231066, states[0] = -93.505096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710565946, states[0] = -93.501243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715619691, states[0] = -93.517085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720101705, states[0] = 3.345339, states[40]= 0.002991
Saving checkpoint... 
Iteration: 721671952, states[0] = -93.515678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726636423, states[0] = -93.543773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736648309, states[0] = -93.516271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747004028, states[0] = 32.931968, states[40]= 0.484453
Saving checkpoint... 
Iteration: 756091263, states[0] = 8.457013, states[40]= 0.002159
Saving checkpoint... 
Iteration: 762339183, states[0] = -93.296765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768634533, states[0] = -93.543464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781394448, states[0] = -93.524126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807433962, states[0] = -93.454572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835247572, states[0] = -93.529853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863107502, states[0] = -93.506615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891043604, states[0] = 26.661582, states[40]= 0.000164
Saving checkpoint... 
Iteration: 918966590, states[0] = -93.543026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946930385, states[0] = -93.509517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974763431, states[0] = -93.499033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003209395, states[0] = -93.531221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031770070, states[0] = -93.498877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060414549, states[0] = -93.522898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088907604, states[0] = -93.497755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117530070, states[0] = -93.518970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118134776, states[0] = -93.505732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118416755, states[0] = -93.502052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118679206, states[0] = -93.499468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118931902, states[0] = -93.497534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119198271, states[0] = -68.229857, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1119432803, states[0] = -93.452822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119643732, states[0] = -93.543911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119888243, states[0] = -93.546174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120140752, states[0] = -93.534169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120387585, states[0] = -93.523762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130472714, states[0] = -93.501421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161739856, states[0] = -93.549092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190313281, states[0] = -93.503146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219691818, states[0] = -93.514265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248848459, states[0] = -93.547409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249099229, states[0] = -93.535927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249357221, states[0] = -93.524661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249620522, states[0] = -93.516093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249859113, states[0] = -93.510381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250130596, states[0] = -93.505556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250373493, states[0] = -93.502308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250719418, states[0] = -93.498888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271311788, states[0] = -93.503017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296358771, states[0] = -93.341418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323266616, states[0] = -93.025421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349720096, states[0] = -93.498703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376307107, states[0] = -93.502885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402543659, states[0] = -93.518037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428853031, states[0] = -93.546931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455586709, states[0] = -93.534117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482369905, states[0] = -93.363322, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.372372
 - CaMKt in component CaMK (millimolar): 0.001367
 - cass in component intracellular_ions (millimolar): 0.000104
 - nai in component intracellular_ions (millimolar): 6.850948
 - nass in component intracellular_ions (millimolar): 6.851075
 - ki in component intracellular_ions (millimolar): 145.005579
 - kss in component intracellular_ions (millimolar): 145.005569
 - cansr in component intracellular_ions (millimolar): 1.865644
 - cajsr in component intracellular_ions (millimolar): 1.865553
 - cai in component intracellular_ions (millimolar): 0.000108
 - m in component INa (dimensionless): 0.004222
 - hf in component INa (dimensionless): 0.850828
 - hs in component INa (dimensionless): 0.850828
 - j in component INa (dimensionless): 0.850830
 - hsp in component INa (dimensionless): 0.673132
 - jp in component INa (dimensionless): 0.850831
 - mL in component INaL (dimensionless): 0.000066
 - hL in component INaL (dimensionless): 0.687016
 - hLp in component INaL (dimensionless): 0.489597
 - a in component Ito (dimensionless): 0.000691
 - iF in component Ito (dimensionless): 0.999830
 - iS in component Ito (dimensionless): 0.999183
 - ap in component Ito (dimensionless): 0.000352
 - iFp in component Ito (dimensionless): 0.999830
 - iSp in component Ito (dimensionless): 0.999674
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999530
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005853
 - xrf in component IKr (dimensionless): 0.000004
 - xrs in component IKr (dimensionless): 0.000658
 - xs1 in component IKs (dimensionless): 0.014589
 - xs2 in component IKs (dimensionless): 0.000104
 - xk1 in component IK1 (dimensionless): 0.997711
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
14:22:42 (10448): called boinc_finish(0)

</stderr_txt>
]]>


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