𝕏

Task 55430482

Name HuVeMOp_20240630122619249330_ORdGradInc_k_25-CLVPET_Block_Kr_15-conf_731_0
Workunit 26321641
Created 30 Jun 2024, 10:26:38 UTC
Sent 30 Jun 2024, 12:03:47 UTC
Report deadline 3 Jul 2024, 14:56:35 UTC
Received 3 Jul 2024, 10:04:54 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232308
Run time 2 hours 54 min 16 sec
CPU time 2 hours 47 min 7 sec
Validate state Valid
Credit 51.17
Device peak FLOPS 4.92 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.07 MB

Stderr output

<core_client_version>7.14.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-CLVPET_Block_Kr_15-conf_731.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-CLVPET_Block_Kr_15-conf_731_0_r1883870247_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-CLVPET_Block_Kr_15-conf_731_0_r1883870247_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 91.390016
     * GNaL_b in INaL: 0.005507
     * Gto_b in Ito: 0.087932
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.026629
     * GKs_b in IKs: 0.002141
     * GK1_b in IK1: 0.156641
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 70.732919
     * GKb_b in IKb: 0.003870
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.024501
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9953444, states[0] = -94.787647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20004018, states[0] = 32.454708, states[40]= 0.350159
Saving checkpoint... 
Iteration: 30195315, states[0] = -93.797998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40273438, states[0] = -94.522970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50075946, states[0] = 8.115001, states[40]= 0.003957
Saving checkpoint... 
Iteration: 59955460, states[0] = -94.710668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69971405, states[0] = -94.714470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79575260, states[0] = 8.507944, states[40]= 0.003917
Saving checkpoint... 
Iteration: 88968730, states[0] = -94.711903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98706373, states[0] = -94.250970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108562685, states[0] = 13.930140, states[40]= 0.002938
Saving checkpoint... 
Iteration: 118104516, states[0] = -9.698293, states[40]= 0.002681
Saving checkpoint... 
Iteration: 127692004, states[0] = -92.548334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137067532, states[0] = 11.953862, states[40]= 0.003343
Saving checkpoint... 
Iteration: 146933949, states[0] = -94.696774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157072212, states[0] = 9.934725, states[40]= 0.003710
Saving checkpoint... 
Iteration: 167030971, states[0] = 25.148334, states[40]= 0.001012
Saving checkpoint... 
Iteration: 177038242, states[0] = 22.876926, states[40]= 0.001267
Saving checkpoint... 
Iteration: 187002805, states[0] = 37.939124, states[40]= 0.511329
Saving checkpoint... 
Iteration: 196538543, states[0] = 22.777518, states[40]= 0.001281
Saving checkpoint... 
Iteration: 206525184, states[0] = 26.645345, states[40]= 0.001075
Saving checkpoint... 
Iteration: 216407553, states[0] = -94.682490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226263382, states[0] = -94.484081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235967658, states[0] = -94.708785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245351960, states[0] = -94.638179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254740012, states[0] = -94.412043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264466435, states[0] = -94.708240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274533944, states[0] = 24.260764, states[40]= 0.001096
Saving checkpoint... 
Iteration: 284296429, states[0] = -94.558981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293763923, states[0] = -94.485179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303266792, states[0] = -94.492744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312982847, states[0] = -94.712830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322818760, states[0] = -94.596265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332891175, states[0] = -94.671377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342370030, states[0] = -94.654886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352049284, states[0] = 19.026333, states[40]= 0.001897
Saving checkpoint... 
Iteration: 362066970, states[0] = 12.197234, states[40]= 0.003299
Saving checkpoint... 
Iteration: 371996337, states[0] = -94.715925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382086384, states[0] = 2.916338, states[40]= 0.004410
Saving checkpoint... 
Iteration: 392100658, states[0] = -6.532492, states[40]= 0.003372
Saving checkpoint... 
Iteration: 402290400, states[0] = -94.546618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412103877, states[0] = -9.132814, states[40]= 0.002804
Saving checkpoint... 
Iteration: 421910105, states[0] = -94.682922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431686666, states[0] = -88.305319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441593085, states[0] = -1.111104, states[40]= 0.004259
Saving checkpoint... 
Iteration: 451240300, states[0] = -94.412049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461062756, states[0] = 13.918951, states[40]= 0.002950
Saving checkpoint... 
Iteration: 471230677, states[0] = -94.377163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480995620, states[0] = -94.715225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490541162, states[0] = 21.893477, states[40]= 0.001409
Saving checkpoint... 
Iteration: 500025457, states[0] = 26.584706, states[40]= 0.001059
Saving checkpoint... 
Iteration: 509604838, states[0] = -9.935090, states[40]= 0.002631
Saving checkpoint... 
Iteration: 519152731, states[0] = -50.002950, states[40]= 0.000120
Saving checkpoint... 
Iteration: 528375291, states[0] = -94.658407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537935231, states[0] = -94.695064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547624614, states[0] = -26.562820, states[40]= 0.001510
Saving checkpoint... 
Iteration: 557249973, states[0] = -94.443321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566987022, states[0] = -94.712689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576706518, states[0] = -94.247887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586681182, states[0] = -80.561777, states[40]= 0.000001
Saving checkpoint... 
Iteration: 596601543, states[0] = -7.231276, states[40]= 0.003221
Saving checkpoint... 
Iteration: 606497308, states[0] = -94.715006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616335796, states[0] = -94.617943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626157647, states[0] = -54.389444, states[40]= 0.000061
Saving checkpoint... 
Iteration: 635684718, states[0] = -85.788868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645610601, states[0] = -14.877683, states[40]= 0.001770
Saving checkpoint... 
Iteration: 655454061, states[0] = -94.702081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665277161, states[0] = -94.516569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674933315, states[0] = -94.693537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684810154, states[0] = -94.581103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694424354, states[0] = -94.689196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703873402, states[0] = -94.655984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713659608, states[0] = -56.164457, states[40]= 0.000046
Saving checkpoint... 
Iteration: 723587950, states[0] = 2.028735, states[40]= 0.004417
Saving checkpoint... 
Iteration: 733323551, states[0] = -94.601180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742975446, states[0] = -94.708652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752649385, states[0] = -47.059521, states[40]= 0.000185
Saving checkpoint... 
Iteration: 762446456, states[0] = -94.698669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772566425, states[0] = 12.424858, states[40]= 0.003255
Saving checkpoint... 
Iteration: 782745645, states[0] = -94.428364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792923382, states[0] = -94.688230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802770615, states[0] = -94.500059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812744102, states[0] = -94.423131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822669924, states[0] = -66.143860, states[40]= 0.000009
Saving checkpoint... 
Iteration: 832737560, states[0] = -94.400579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842356357, states[0] = -94.639723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852446797, states[0] = -94.698364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862132409, states[0] = -32.850951, states[40]= 0.001060
Saving checkpoint... 
Iteration: 871579669, states[0] = 6.443660, states[40]= 0.004189
Saving checkpoint... 
Iteration: 881406693, states[0] = -94.678684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891064898, states[0] = 13.053763, states[40]= 0.003128
Saving checkpoint... 
Iteration: 900624177, states[0] = -26.208661, states[40]= 0.001518
Saving checkpoint... 
Iteration: 910023037, states[0] = 27.092773, states[40]= 0.001318
Saving checkpoint... 
Iteration: 919981241, states[0] = -94.709428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929768371, states[0] = -94.493739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939653889, states[0] = -51.027106, states[40]= 0.000103
Saving checkpoint... 
Iteration: 949652376, states[0] = -49.686610, states[40]= 0.000126
Saving checkpoint... 
Iteration: 959481589, states[0] = -94.709331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969144790, states[0] = -43.091081, states[40]= 0.000321
Saving checkpoint... 
Iteration: 979140639, states[0] = -39.593269, states[40]= 0.000505
Saving checkpoint... 
Iteration: 988867005, states[0] = -94.649061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998581069, states[0] = 5.742297, states[40]= 0.004256
Saving checkpoint... 
Iteration: 1008166631, states[0] = -62.776752, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1018063335, states[0] = 13.687584, states[40]= 0.002998
Saving checkpoint... 
Iteration: 1027776837, states[0] = -94.514026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037422763, states[0] = -94.686725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047215323, states[0] = -94.310352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056822687, states[0] = -94.598369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066470304, states[0] = -94.705531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076327617, states[0] = -94.605109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086279966, states[0] = -94.520941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095929342, states[0] = -94.689646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105370202, states[0] = -94.651300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115225353, states[0] = -94.353304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124853917, states[0] = -94.635874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134437357, states[0] = -94.693083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144339831, states[0] = -94.620245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154184599, states[0] = -85.612623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163932094, states[0] = -94.690592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173544227, states[0] = 20.831269, states[40]= 0.001577
Saving checkpoint... 
Iteration: 1183418721, states[0] = -94.683932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192979247, states[0] = -94.707543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202957515, states[0] = -94.700647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212731813, states[0] = -94.377760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222438372, states[0] = -94.693092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232244799, states[0] = -94.423362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241657851, states[0] = -54.569415, states[40]= 0.000059
Saving checkpoint... 
Iteration: 1251381329, states[0] = -94.659669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261049600, states[0] = 18.913227, states[40]= 0.001920
Saving checkpoint... 
Iteration: 1270459948, states[0] = -94.701164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279900982, states[0] = -94.673242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289338311, states[0] = -94.617716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299271484, states[0] = -94.499779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309128916, states[0] = -30.027509, states[40]= 0.001315
Saving checkpoint... 
Iteration: 1319040063, states[0] = 22.269180, states[40]= 0.001354
Saving checkpoint... 
Iteration: 1328697645, states[0] = -93.870249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338520483, states[0] = 27.520502, states[40]= 0.002052
Saving checkpoint... 
Iteration: 1348006612, states[0] = 28.278692, states[40]= 0.157074
Saving checkpoint... 
Iteration: 1357677125, states[0] = -74.717845, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1367509543, states[0] = 27.680819, states[40]= 0.058156
Saving checkpoint... 
Iteration: 1377218342, states[0] = -94.322728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387022666, states[0] = 27.163008, states[40]= 0.001386
Saving checkpoint... 
Iteration: 1396921230, states[0] = -94.684190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406882157, states[0] = -94.659544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416452541, states[0] = -94.697806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425990893, states[0] = -94.709475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434914226, states[0] = -94.680286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444581364, states[0] = 5.593347, states[40]= 0.004269
Saving checkpoint... 
Iteration: 1454003589, states[0] = 34.149587, states[40]= 0.421321
Saving checkpoint... 
Iteration: 1463584743, states[0] = 3.820523, states[40]= 0.004383
Saving checkpoint... 
Iteration: 1473413865, states[0] = -94.679899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483588739, states[0] = 1.571848, states[40]= 0.004412
Saving checkpoint... 
Iteration: 1493538385, states[0] = 22.832926, states[40]= 0.001274
Saving checkpoint... 
Iteration: 1503667533, states[0] = -8.270299, states[40]= 0.004684
Saving checkpoint... 
Iteration: 1513386524, states[0] = -61.088329, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1523414914, states[0] = 28.324793, states[40]= 0.010364
Saving checkpoint... 
Iteration: 1533260124, states[0] = 27.433779, states[40]= 0.052115
Saving checkpoint... 
Iteration: 1543040444, states[0] = 22.385228, states[40]= 0.000840
Saving checkpoint... 
Iteration: 1552675652, states[0] = -94.583396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1562418915, states[0] = -94.421794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1572282131, states[0] = -94.211382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581823327, states[0] = -94.196950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1591260539, states[0] = -94.374819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1601220909, states[0] = -92.610223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1611005754, states[0] = -94.353786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1620323357, states[0] = -94.081140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1630143085, states[0] = -23.964590, states[40]= 0.002149
Saving checkpoint... 
Iteration: 1639967360, states[0] = -94.249002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649470268, states[0] = -94.247629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1659175493, states[0] = -94.246940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1668662852, states[0] = -94.253213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1678128818, states[0] = -94.248569, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.109658
 - CaMKt in component CaMK (millimolar): 0.001202
 - cass in component intracellular_ions (millimolar): 0.000089
 - nai in component intracellular_ions (millimolar): 6.414293
 - nass in component intracellular_ions (millimolar): 6.414382
 - ki in component intracellular_ions (millimolar): 145.465892
 - kss in component intracellular_ions (millimolar): 145.465881
 - cansr in component intracellular_ions (millimolar): 1.608462
 - cajsr in component intracellular_ions (millimolar): 1.608478
 - cai in component intracellular_ions (millimolar): 0.000092
 - m in component INa (dimensionless): 0.003920
 - hf in component INa (dimensionless): 0.865560
 - hs in component INa (dimensionless): 0.865560
 - j in component INa (dimensionless): 0.865561
 - hsp in component INa (dimensionless): 0.699208
 - jp in component INa (dimensionless): 0.865562
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707786
 - hLp in component INaL (dimensionless): 0.514083
 - a in component Ito (dimensionless): 0.000658
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.997589
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.999183
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998767
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003318
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001984
 - xs1 in component IKs (dimensionless): 0.024344
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997538
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
06:56:10 (7606): called boinc_finish(0)

</stderr_txt>
]]>


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