𝕏

Task 55430480

Name HuVeMOp_20240630122619249330_ORdGradInc_k_25-CLVPET_Block_Kr_15-conf_531_0
Workunit 26321640
Created 30 Jun 2024, 10:26:38 UTC
Sent 30 Jun 2024, 12:03:40 UTC
Report deadline 3 Jul 2024, 14:56:28 UTC
Received 3 Jul 2024, 10:04:54 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232308
Run time 2 hours 54 min 38 sec
CPU time 2 hours 47 min 6 sec
Validate state Valid
Credit 51.26
Device peak FLOPS 4.92 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.07 MB

Stderr output

<core_client_version>7.14.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-CLVPET_Block_Kr_15-conf_531.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-CLVPET_Block_Kr_15-conf_531_0_r1473012461_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-CLVPET_Block_Kr_15-conf_531_0_r1473012461_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 98.809096
     * GNaL_b in INaL: 0.006896
     * Gto_b in Ito: 0.070817
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.026842
     * GKs_b in IKs: 0.002124
     * GK1_b in IK1: 0.149207
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 66.783369
     * GKb_b in IKb: 0.003814
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038498
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9918766, states[0] = -94.866192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 19647513, states[0] = -46.005479, states[40]= 0.000184
Saving checkpoint... 
Iteration: 29603318, states[0] = -8.607654, states[40]= 0.003075
Saving checkpoint... 
Iteration: 39646712, states[0] = -44.054489, states[40]= 0.000275
Saving checkpoint... 
Iteration: 49279069, states[0] = -94.636323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59406620, states[0] = -94.785633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69530545, states[0] = 26.053803, states[40]= 0.002002
Saving checkpoint... 
Iteration: 79573100, states[0] = 9.858472, states[40]= 0.004833
Saving checkpoint... 
Iteration: 89607579, states[0] = -11.591104, states[40]= 0.002425
Saving checkpoint... 
Iteration: 99115532, states[0] = -18.238730, states[40]= 0.001595
Saving checkpoint... 
Iteration: 108999028, states[0] = -94.814967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118702650, states[0] = -94.235935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128667868, states[0] = -62.912729, states[40]= 0.000014
Saving checkpoint... 
Iteration: 138391926, states[0] = -94.770712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147775190, states[0] = -94.618711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157135222, states[0] = -33.902132, states[40]= 0.000990
Saving checkpoint... 
Iteration: 166572397, states[0] = 10.229458, states[40]= 0.004807
Saving checkpoint... 
Iteration: 176234942, states[0] = -94.503923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185865303, states[0] = -94.749729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195279250, states[0] = -94.627237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204873814, states[0] = -94.756710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214142069, states[0] = -39.461732, states[40]= 0.000517
Saving checkpoint... 
Iteration: 224058241, states[0] = 16.183314, states[40]= 0.003890
Saving checkpoint... 
Iteration: 234220777, states[0] = -94.450667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243800589, states[0] = -94.668514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252957494, states[0] = -94.801524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262886379, states[0] = -94.765859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272733528, states[0] = -94.498451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282568188, states[0] = 12.097826, states[40]= 0.004583
Saving checkpoint... 
Iteration: 292100973, states[0] = -6.197542, states[40]= 0.003686
Saving checkpoint... 
Iteration: 301991111, states[0] = -94.811010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311898568, states[0] = -94.773737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321960692, states[0] = -94.802331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331873659, states[0] = -94.756040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341690259, states[0] = -90.622045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351339144, states[0] = -94.722729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361094445, states[0] = -1.588647, states[40]= 0.004626
Saving checkpoint... 
Iteration: 370443110, states[0] = -94.795796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380351325, states[0] = -94.735737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390425322, states[0] = -94.788016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400066722, states[0] = 12.726581, states[40]= 0.004494
Saving checkpoint... 
Iteration: 410052930, states[0] = 18.222216, states[40]= 0.003470
Saving checkpoint... 
Iteration: 419890366, states[0] = -94.768032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429816219, states[0] = -94.692703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439195798, states[0] = -93.406099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449008577, states[0] = 30.276975, states[40]= 0.075152
Saving checkpoint... 
Iteration: 458397310, states[0] = -94.772425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468305585, states[0] = -94.676095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478454752, states[0] = -94.799751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488421103, states[0] = -94.785625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497925285, states[0] = -94.787616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507818327, states[0] = -94.695472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517571493, states[0] = 10.642670, states[40]= 0.004764
Saving checkpoint... 
Iteration: 527189095, states[0] = -89.556606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536826001, states[0] = -94.705903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546353961, states[0] = -94.737771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556199669, states[0] = -94.031217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566040069, states[0] = 22.904341, states[40]= 0.002512
Saving checkpoint... 
Iteration: 575678517, states[0] = -75.098388, states[40]= 0.000002
Saving checkpoint... 
Iteration: 585389118, states[0] = -94.766596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595490630, states[0] = -94.809847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605598248, states[0] = -4.188120, states[40]= 0.004143
Saving checkpoint... 
Iteration: 615296443, states[0] = -94.659819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625005480, states[0] = 32.632601, states[40]= 0.208427
Saving checkpoint... 
Iteration: 634598699, states[0] = -4.512056, states[40]= 0.004074
Saving checkpoint... 
Iteration: 644297742, states[0] = -94.662050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653161900, states[0] = -57.078187, states[40]= 0.000038
Saving checkpoint... 
Iteration: 663021299, states[0] = 28.582987, states[40]= 0.002609
Saving checkpoint... 
Iteration: 672648675, states[0] = -45.083883, states[40]= 0.000242
Saving checkpoint... 
Iteration: 681958889, states[0] = -94.800450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691651701, states[0] = -47.755493, states[40]= 0.000164
Saving checkpoint... 
Iteration: 701634468, states[0] = -33.279626, states[40]= 0.001053
Saving checkpoint... 
Iteration: 711516961, states[0] = 29.347195, states[40]= 0.005801
Saving checkpoint... 
Iteration: 721433575, states[0] = -94.790591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730848955, states[0] = -94.732067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740544898, states[0] = 21.181784, states[40]= 0.002846
Saving checkpoint... 
Iteration: 750076434, states[0] = 8.355468, states[40]= 0.004971
Saving checkpoint... 
Iteration: 759943700, states[0] = -94.794646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769298543, states[0] = -94.663027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778813870, states[0] = -94.687980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788380308, states[0] = -94.759566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798077071, states[0] = 8.049991, states[40]= 0.004992
Saving checkpoint... 
Iteration: 807969446, states[0] = -94.803367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817780164, states[0] = -94.626868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827488656, states[0] = -94.808544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837075898, states[0] = 8.610711, states[40]= 0.004953
Saving checkpoint... 
Iteration: 846894642, states[0] = -94.769343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856476246, states[0] = -94.805174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866353323, states[0] = -94.736004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875879263, states[0] = -94.758469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885482248, states[0] = -94.806705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895121682, states[0] = -23.150797, states[40]= 0.001625
Saving checkpoint... 
Iteration: 905172044, states[0] = -67.226068, states[40]= 0.000007
Saving checkpoint... 
Iteration: 914982964, states[0] = -94.806788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924836618, states[0] = -94.717751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934466608, states[0] = -94.802050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944376006, states[0] = -94.755719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954001990, states[0] = 45.560966, states[40]= 0.418788
Saving checkpoint... 
Iteration: 964016949, states[0] = 29.349109, states[40]= 0.005819
Saving checkpoint... 
Iteration: 973830315, states[0] = -94.709902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983258734, states[0] = -94.574164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993030740, states[0] = 26.036704, states[40]= 0.002029
Saving checkpoint... 
Iteration: 1002878631, states[0] = -94.757538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012652798, states[0] = -48.735204, states[40]= 0.000142
Saving checkpoint... 
Iteration: 1022373947, states[0] = -94.753814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031739642, states[0] = -94.516528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041345264, states[0] = -94.727069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051223765, states[0] = -94.459662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061168751, states[0] = -63.741412, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1071328289, states[0] = -94.706977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080737789, states[0] = -94.510169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090472718, states[0] = -94.803335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100024099, states[0] = 27.931465, states[40]= 0.002098
Saving checkpoint... 
Iteration: 1109620579, states[0] = -22.268483, states[40]= 0.001604
Saving checkpoint... 
Iteration: 1119250691, states[0] = -94.550828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128892602, states[0] = -94.767008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138581284, states[0] = 5.961475, states[40]= 0.005086
Saving checkpoint... 
Iteration: 1148111722, states[0] = -14.968840, states[40]= 0.001861
Saving checkpoint... 
Iteration: 1158136097, states[0] = -34.583654, states[40]= 0.000922
Saving checkpoint... 
Iteration: 1167925786, states[0] = -94.785476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177883751, states[0] = -94.760716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187679154, states[0] = -75.960804, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1197274548, states[0] = -94.613000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206933885, states[0] = -94.789004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216721148, states[0] = -94.448611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226575038, states[0] = 9.016889, states[40]= 0.004921
Saving checkpoint... 
Iteration: 1236253805, states[0] = -94.559484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245678736, states[0] = -75.388184, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1255534682, states[0] = 24.758087, states[40]= 0.002199
Saving checkpoint... 
Iteration: 1265462659, states[0] = -94.799625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275406506, states[0] = -94.775052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284999162, states[0] = -94.809370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294646057, states[0] = -42.816839, states[40]= 0.000332
Saving checkpoint... 
Iteration: 1304608423, states[0] = -12.194441, states[40]= 0.002305
Saving checkpoint... 
Iteration: 1314340043, states[0] = -94.720326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323871992, states[0] = -94.751164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333189398, states[0] = -89.842937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343190279, states[0] = -90.628086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353178688, states[0] = -75.321882, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1363233641, states[0] = -94.494912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372963834, states[0] = -94.799622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382840940, states[0] = -94.721097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392073886, states[0] = 9.553581, states[40]= 0.004875
Saving checkpoint... 
Iteration: 1401744214, states[0] = -94.529986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411821494, states[0] = -94.696704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421711138, states[0] = -94.394820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431737320, states[0] = -94.507326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441606508, states[0] = -10.600738, states[40]= 0.002635
Saving checkpoint... 
Iteration: 1451106070, states[0] = -10.239759, states[40]= 0.002716
Saving checkpoint... 
Iteration: 1460806476, states[0] = -94.674008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470535443, states[0] = 24.502632, states[40]= 0.002239
Saving checkpoint... 
Iteration: 1480189090, states[0] = -89.540668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489761950, states[0] = -94.580957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499356575, states[0] = -94.736915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1508643617, states[0] = -26.662526, states[40]= 0.001567
Saving checkpoint... 
Iteration: 1518369807, states[0] = -94.688341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1528033805, states[0] = -94.630521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537744022, states[0] = -94.695425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1547363944, states[0] = -94.677066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1557116589, states[0] = -11.590662, states[40]= 0.002311
Saving checkpoint... 
Iteration: 1566773759, states[0] = -94.574714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1576379039, states[0] = -94.464644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1585830082, states[0] = -94.456947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1595605294, states[0] = -94.446033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1605356455, states[0] = -94.434553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1614881606, states[0] = -94.332030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1624748196, states[0] = -94.343419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1634666998, states[0] = -94.335500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1643568704, states[0] = -94.345300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1653433579, states[0] = -94.342700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1663498646, states[0] = -94.337264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1673594551, states[0] = -94.331874, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.188702
 - CaMKt in component CaMK (millimolar): 0.001127
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.398036
 - nass in component intracellular_ions (millimolar): 6.398121
 - ki in component intracellular_ions (millimolar): 145.503431
 - kss in component intracellular_ions (millimolar): 145.503420
 - cansr in component intracellular_ions (millimolar): 1.559815
 - cajsr in component intracellular_ions (millimolar): 1.559802
 - cai in component intracellular_ions (millimolar): 0.000089
 - m in component INa (dimensionless): 0.003889
 - hf in component INa (dimensionless): 0.867064
 - hs in component INa (dimensionless): 0.867064
 - j in component INa (dimensionless): 0.867065
 - hsp in component INa (dimensionless): 0.701932
 - jp in component INa (dimensionless): 0.867066
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.709964
 - hLp in component INaL (dimensionless): 0.516715
 - a in component Ito (dimensionless): 0.000654
 - iF in component Ito (dimensionless): 0.999852
 - iS in component Ito (dimensionless): 0.997599
 - ap in component Ito (dimensionless): 0.000333
 - iFp in component Ito (dimensionless): 0.999852
 - iSp in component Ito (dimensionless): 0.999189
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998721
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002957
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.002008
 - xs1 in component IKs (dimensionless): 0.024732
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997518
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:54:10 (7475): called boinc_finish(0)

</stderr_txt>
]]>


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