𝕏

Task 55430464

Name HuVeMOp_20240630122619249330_ORdGradInc_k_25-Pueyo_APDR-conf_430_0
Workunit 26321632
Created 30 Jun 2024, 10:26:38 UTC
Sent 30 Jun 2024, 12:05:17 UTC
Report deadline 3 Jul 2024, 21:41:17 UTC
Received 30 Jun 2024, 14:36:14 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241023
Run time 2 hours 30 min 40 sec
CPU time 2 hours 28 min 31 sec
Validate state Valid
Credit 60.41
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.25 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-Pueyo_APDR-conf_430.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-Pueyo_APDR-conf_430_0_r52408796_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-Pueyo_APDR-conf_430_0_r52408796_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 97.587882
     * GNaL_b in INaL: 0.004914
     * Gto_b in Ito: 0.085280
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031740
     * GKs_b in IKs: 0.002045
     * GK1_b in IK1: 0.152583
     * Gncx_b in INaCa_i: 0.000975
     * Pnak_b in INaK: 66.335638
     * GKb_b in IKb: 0.003694
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.022920
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14401077, states[0] = -94.874918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28053224, states[0] = 9.347959, states[40]= 0.004893
Saving checkpoint... 
Iteration: 41884007, states[0] = -94.833455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55864622, states[0] = -94.817660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70173549, states[0] = -94.389199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84763103, states[0] = -94.728527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99601296, states[0] = -22.501928, states[40]= 0.000830
Saving checkpoint... 
Iteration: 114134321, states[0] = -54.824058, states[40]= 0.000013
Saving checkpoint... 
Iteration: 127958913, states[0] = -94.834161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141700816, states[0] = -94.614516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155464017, states[0] = -94.834142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169552545, states[0] = 10.132528, states[40]= 0.004906
Saving checkpoint... 
Iteration: 183822483, states[0] = -94.779450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197511913, states[0] = 22.294206, states[40]= 0.032865
Saving checkpoint... 
Iteration: 211304250, states[0] = -94.765243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224960627, states[0] = -94.832784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238599917, states[0] = -20.999830, states[40]= 0.000912
Saving checkpoint... 
Iteration: 252395793, states[0] = -94.815874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266311135, states[0] = -94.770662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281085226, states[0] = -7.568633, states[40]= 0.002873
Saving checkpoint... 
Iteration: 295761953, states[0] = -94.720730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311080938, states[0] = -4.309371, states[40]= 0.003559
Saving checkpoint... 
Iteration: 326207846, states[0] = -94.628641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340995354, states[0] = -94.838165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355720546, states[0] = -94.654520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370141097, states[0] = -61.877565, states[40]= 0.000004
Saving checkpoint... 
Iteration: 385198063, states[0] = -94.606861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400040357, states[0] = 14.834861, states[40]= 0.005135
Saving checkpoint... 
Iteration: 414890713, states[0] = -94.813903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429954437, states[0] = -94.831327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445223682, states[0] = -94.660433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460364611, states[0] = -94.803102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475693186, states[0] = -94.595122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490896705, states[0] = -94.815965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506134308, states[0] = -54.648086, states[40]= 0.000013
Saving checkpoint... 
Iteration: 521332881, states[0] = -94.785777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536500024, states[0] = -91.868501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551554051, states[0] = 9.528218, states[40]= 0.004891
Saving checkpoint... 
Iteration: 566597138, states[0] = -18.353402, states[40]= 0.001103
Saving checkpoint... 
Iteration: 581893316, states[0] = -94.814715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597082478, states[0] = -5.428593, states[40]= 0.003331
Saving checkpoint... 
Iteration: 611517909, states[0] = 21.301502, states[40]= 0.011369
Saving checkpoint... 
Iteration: 625835580, states[0] = -94.787385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640309067, states[0] = -94.768716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654455675, states[0] = -94.831407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668819251, states[0] = -94.776444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683037430, states[0] = 15.887092, states[40]= 0.005260
Saving checkpoint... 
Iteration: 697776752, states[0] = -94.738128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712280160, states[0] = -94.741830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726323392, states[0] = -94.779336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739833969, states[0] = -94.786301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753467088, states[0] = -94.833470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767186628, states[0] = -94.575727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780730806, states[0] = -94.673155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794318792, states[0] = -94.776019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807995984, states[0] = -94.837902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822063319, states[0] = 5.529252, states[40]= 0.004755
Saving checkpoint... 
Iteration: 836856193, states[0] = -94.798742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851309087, states[0] = -94.768577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865825581, states[0] = -94.780736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880341312, states[0] = -94.790633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894951760, states[0] = -94.830442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910212849, states[0] = -94.638720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925363206, states[0] = -94.802101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939738685, states[0] = -94.686395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954142556, states[0] = -63.501368, states[40]= 0.000003
Saving checkpoint... 
Iteration: 968729325, states[0] = -94.670390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983032217, states[0] = 17.647947, states[40]= 0.005620
Saving checkpoint... 
Iteration: 997251371, states[0] = -94.705788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011953690, states[0] = -94.830748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026594393, states[0] = -15.749372, states[40]= 0.001380
Saving checkpoint... 
Iteration: 1041307925, states[0] = -94.767501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055560697, states[0] = 6.708178, states[40]= 0.004807
Saving checkpoint... 
Iteration: 1070167029, states[0] = -93.257586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084241594, states[0] = -94.690965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098425443, states[0] = -94.824174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112447279, states[0] = -94.829344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126491048, states[0] = -94.836990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140315069, states[0] = -94.773008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154156079, states[0] = -81.836314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167802541, states[0] = -94.762932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181645207, states[0] = -66.568904, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1195477908, states[0] = -94.834966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209747414, states[0] = -94.699832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224403883, states[0] = -94.817810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238715895, states[0] = -94.644682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252603507, states[0] = -24.401328, states[40]= 0.000739
Saving checkpoint... 
Iteration: 1267399025, states[0] = -94.816182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282160077, states[0] = -87.778514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296814811, states[0] = -94.772698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311308061, states[0] = -94.767412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325807129, states[0] = -94.766645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340439695, states[0] = -94.827496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354761237, states[0] = -94.719006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369109558, states[0] = -30.135803, states[40]= 0.000467
Saving checkpoint... 
Iteration: 1383303470, states[0] = -94.763563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397604577, states[0] = -25.414902, states[40]= 0.000692
Saving checkpoint... 
Iteration: 1412300868, states[0] = -94.761311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426848933, states[0] = -94.794511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441316967, states[0] = -94.774203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455783339, states[0] = -94.744629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470171879, states[0] = -94.216495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484516042, states[0] = 21.619412, states[40]= 0.014747
Saving checkpoint... 
Iteration: 1498981431, states[0] = -94.835297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1513381655, states[0] = -94.922085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1527746984, states[0] = -94.045014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1542212592, states[0] = -95.015430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1555884616, states[0] = -21.876055, states[40]= 0.000906
Saving checkpoint... 
Iteration: 1569999285, states[0] = -38.178893, states[40]= 0.000172
Saving checkpoint... 
Iteration: 1584024380, states[0] = 19.120194, states[40]= 0.008101
Saving checkpoint... 
Iteration: 1598087583, states[0] = -95.127372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1612461453, states[0] = -95.104281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1626829587, states[0] = -95.064169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1642142869, states[0] = -95.083563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1657371124, states[0] = -94.940554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1672170494, states[0] = -95.115443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686925060, states[0] = 18.818362, states[40]= 0.007876
Saving checkpoint... 
Iteration: 1701985421, states[0] = -23.391414, states[40]= 0.000808
Saving checkpoint... 
Iteration: 1717216113, states[0] = 21.678571, states[40]= 0.016153
Saving checkpoint... 
Iteration: 1732524391, states[0] = 19.062960, states[40]= 0.008086
Saving checkpoint... 
Iteration: 1747283882, states[0] = -21.697032, states[40]= 0.000920
Saving checkpoint... 
Iteration: 1762051686, states[0] = -94.769553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1777197995, states[0] = -95.138839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1792454745, states[0] = -95.098962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807516565, states[0] = 21.150160, states[40]= 0.012863
Saving checkpoint... 
Iteration: 1822694026, states[0] = -94.634263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1837592638, states[0] = -15.321181, states[40]= 0.001444
Saving checkpoint... 
Iteration: 1852328589, states[0] = -94.798852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1867350772, states[0] = -94.805996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1881916428, states[0] = -94.828169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1896522243, states[0] = 20.381779, states[40]= 0.007733
Saving checkpoint... 
Iteration: 1911424545, states[0] = -94.826291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1925891062, states[0] = -94.814837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1940020393, states[0] = 20.812784, states[40]= 0.008832
Saving checkpoint... 
Iteration: 1953959107, states[0] = -94.831933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1967773524, states[0] = -94.734084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1981662614, states[0] = -90.620140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1995558289, states[0] = 7.750480, states[40]= 0.004843
Saving checkpoint... 
Iteration: 2009722530, states[0] = -94.657207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2024600565, states[0] = -21.616230, states[40]= 0.000877
Saving checkpoint... 
Iteration: 2039665390, states[0] = -92.556219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2054064633, states[0] = 4.920159, states[40]= 0.004722
Saving checkpoint... 
Iteration: 2068299147, states[0] = -94.759285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2082293717, states[0] = -94.754333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2096531840, states[0] = 17.768631, states[40]= 0.005655
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.713303
 - CaMKt in component CaMK (millimolar): 0.007211
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.728629
 - nass in component intracellular_ions (millimolar): 6.728689
 - ki in component intracellular_ions (millimolar): 145.243901
 - kss in component intracellular_ions (millimolar): 145.243883
 - cansr in component intracellular_ions (millimolar): 1.330852
 - cajsr in component intracellular_ions (millimolar): 1.292844
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003688
 - hf in component INa (dimensionless): 0.876691
 - hs in component INa (dimensionless): 0.876685
 - j in component INa (dimensionless): 0.876652
 - hsp in component INa (dimensionless): 0.719619
 - jp in component INa (dimensionless): 0.876630
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.704802
 - hLp in component INaL (dimensionless): 0.446031
 - a in component Ito (dimensionless): 0.000631
 - iF in component Ito (dimensionless): 0.999865
 - iS in component Ito (dimensionless): 0.620849
 - ap in component Ito (dimensionless): 0.000322
 - iFp in component Ito (dimensionless): 0.999865
 - iSp in component Ito (dimensionless): 0.695583
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937191
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999892
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001677
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.326413
 - xs1 in component IKs (dimensionless): 0.237607
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997386
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:36:01 (595797): called boinc_finish(0)

</stderr_txt>
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