𝕏

Task 55430176

Name HuVeMOp_20240630122619249330_ORdGradInc_k_25-CLVPET_Block_Kr_15-conf_610_0
Workunit 26321488
Created 30 Jun 2024, 10:26:28 UTC
Sent 30 Jun 2024, 11:59:32 UTC
Report deadline 3 Jul 2024, 14:52:20 UTC
Received 3 Jul 2024, 7:54:07 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 199488
Run time 1 hours 29 min 41 sec
CPU time 1 hours 29 min 41 sec
Validate state Valid
Credit 45.91
Device peak FLOPS 4.04 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.14 MB
Peak swap size 6.21 MB
Peak disk usage 0.04 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-CLVPET_Block_Kr_15-conf_610.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-CLVPET_Block_Kr_15-conf_610_0_r2143958920_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122619249330_ORdGradInc_k_25-CLVPET_Block_Kr_15-conf_610_0_r2143958920_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 117.276621
     * GNaL_b in INaL: 0.006630
     * Gto_b in Ito: 0.075542
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.028876
     * GKs_b in IKs: 0.001889
     * GK1_b in IK1: 0.174211
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 70.874494
     * GKb_b in IKb: 0.003851
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033725
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7106337, states[0] = -15.877974, states[40]= 0.001522
Saving checkpoint... 
Iteration: 17855143, states[0] = -94.826091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28257201, states[0] = -94.667813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38813543, states[0] = -94.755853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48503122, states[0] = 40.228758, states[40]= 0.403981
Saving checkpoint... 
Iteration: 57918740, states[0] = -94.831432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68492704, states[0] = -94.852391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78816834, states[0] = -94.751808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89381779, states[0] = -94.809109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99988392, states[0] = -94.849401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110260490, states[0] = -94.654758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120835152, states[0] = -94.770479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128049038, states[0] = 18.842081, states[40]= 0.003649
Saving checkpoint... 
Iteration: 138566837, states[0] = 11.524043, states[40]= 0.004901
Saving checkpoint... 
Iteration: 149137099, states[0] = -40.606577, states[40]= 0.000413
Saving checkpoint... 
Iteration: 159711641, states[0] = -94.509551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170258457, states[0] = -94.649140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181106745, states[0] = -14.383210, states[40]= 0.001955
Saving checkpoint... 
Iteration: 191533438, states[0] = 24.453253, states[40]= 0.002589
Saving checkpoint... 
Iteration: 202184185, states[0] = -93.571932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212098704, states[0] = -7.403172, states[40]= 0.003464
Saving checkpoint... 
Iteration: 222334935, states[0] = -94.769298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232762237, states[0] = -94.657397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243342547, states[0] = -94.776652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253677137, states[0] = -88.461211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264322051, states[0] = -94.755110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274896736, states[0] = -94.815511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284885880, states[0] = -94.809297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295673305, states[0] = -82.376139, states[40]= 0.000001
Saving checkpoint... 
Iteration: 306100997, states[0] = -9.325964, states[40]= 0.002985
Saving checkpoint... 
Iteration: 316425504, states[0] = -94.828807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326857900, states[0] = -94.789684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337457668, states[0] = -94.839773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347709771, states[0] = -94.501734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357917921, states[0] = -94.825499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367798844, states[0] = -94.724093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377616867, states[0] = -23.234254, states[40]= 0.001500
Saving checkpoint... 
Iteration: 387869013, states[0] = -94.797889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398243885, states[0] = -94.611621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408772122, states[0] = -94.677652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419260561, states[0] = -94.652992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429958469, states[0] = -94.839700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439888320, states[0] = -94.810232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450217965, states[0] = -94.531102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460781750, states[0] = -94.695739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471182518, states[0] = -93.008351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481790166, states[0] = -94.710130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492193084, states[0] = -94.388523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502732330, states[0] = -94.577963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512615380, states[0] = -21.962732, states[40]= 0.001491
Saving checkpoint... 
Iteration: 523062172, states[0] = 13.576977, states[40]= 0.004628
Saving checkpoint... 
Iteration: 533709748, states[0] = -94.501027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544318371, states[0] = -94.749810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554763735, states[0] = -94.659618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565501466, states[0] = 50.296182, states[40]= 0.276314
Saving checkpoint... 
Iteration: 575939237, states[0] = -94.833112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586562355, states[0] = 13.498792, states[40]= 0.004640
Saving checkpoint... 
Iteration: 596381288, states[0] = -94.805443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606965366, states[0] = -94.841033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617504590, states[0] = 34.418645, states[40]= 0.279416
Saving checkpoint... 
Iteration: 628327110, states[0] = -94.759640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639014965, states[0] = 28.910926, states[40]= 0.010642
Saving checkpoint... 
Iteration: 649811583, states[0] = -94.740937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660567704, states[0] = 11.139536, states[40]= 0.004947
Saving checkpoint... 
Iteration: 670880119, states[0] = -94.804458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681778731, states[0] = -94.689491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692683891, states[0] = -93.487256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703155013, states[0] = -57.909591, states[40]= 0.000031
Saving checkpoint... 
Iteration: 713089012, states[0] = -0.276548, states[40]= 0.004932
Saving checkpoint... 
Iteration: 723341895, states[0] = -94.774443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733846222, states[0] = -94.778408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743865899, states[0] = -94.794461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753898755, states[0] = -94.815009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764320788, states[0] = -94.751976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774594889, states[0] = -4.390535, states[40]= 0.004191
Saving checkpoint... 
Iteration: 784969006, states[0] = -94.841406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795098826, states[0] = -7.500255, states[40]= 0.003440
Saving checkpoint... 
Iteration: 805365355, states[0] = -94.793856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815773563, states[0] = -94.679165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825468990, states[0] = -94.841269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835748808, states[0] = -94.623188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846191879, states[0] = -94.359423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856636155, states[0] = -39.741349, states[40]= 0.000461
Saving checkpoint... 
Iteration: 866845249, states[0] = -94.777087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877354596, states[0] = -94.785184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887687765, states[0] = -94.145577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897472106, states[0] = -94.841823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907930508, states[0] = -94.828830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917997693, states[0] = -94.847349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928169068, states[0] = -75.271390, states[40]= 0.000002
Saving checkpoint... 
Iteration: 938577227, states[0] = 6.521145, states[40]= 0.005260
Saving checkpoint... 
Iteration: 949089691, states[0] = -0.721020, states[40]= 0.004872
Saving checkpoint... 
Iteration: 959385741, states[0] = -94.806995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969316851, states[0] = -94.746556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979216091, states[0] = -94.522745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989559039, states[0] = 14.894550, states[40]= 0.004415
Saving checkpoint... 
Iteration: 999943762, states[0] = -94.833270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010065669, states[0] = 12.054753, states[40]= 0.004839
Saving checkpoint... 
Iteration: 1020052971, states[0] = 17.333995, states[40]= 0.003960
Saving checkpoint... 
Iteration: 1029790411, states[0] = -94.708726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040037020, states[0] = 23.237506, states[40]= 0.002790
Saving checkpoint... 
Iteration: 1049518553, states[0] = 28.418526, states[40]= 0.004556
Saving checkpoint... 
Iteration: 1060076576, states[0] = 6.857225, states[40]= 0.005251
Saving checkpoint... 
Iteration: 1070335286, states[0] = -94.766835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080827719, states[0] = -94.758823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091180259, states[0] = -91.705635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101192645, states[0] = -94.377258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111711658, states[0] = -94.506246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121638926, states[0] = -42.238140, states[40]= 0.000333
Saving checkpoint... 
Iteration: 1131785815, states[0] = -94.700677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142066672, states[0] = 11.606819, states[40]= 0.004894
Saving checkpoint... 
Iteration: 1152365978, states[0] = -94.793178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162489893, states[0] = -94.845002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172870145, states[0] = -94.796116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183105709, states[0] = -13.452167, states[40]= 0.002106
Saving checkpoint... 
Iteration: 1193237148, states[0] = -94.590046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203045158, states[0] = 20.307666, states[40]= 0.003353
Saving checkpoint... 
Iteration: 1213536293, states[0] = 23.489310, states[40]= 0.002746
Saving checkpoint... 
Iteration: 1223954066, states[0] = -94.835805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234218378, states[0] = -94.529938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244669430, states[0] = -75.839527, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1254896604, states[0] = -94.812219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265554986, states[0] = 16.538885, states[40]= 0.004115
Saving checkpoint... 
Iteration: 1275447023, states[0] = -94.833440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285739949, states[0] = -94.597776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296255072, states[0] = -94.637266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306512543, states[0] = 29.132938, states[40]= 0.021739
Saving checkpoint... 
Iteration: 1316864986, states[0] = -94.791903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327284620, states[0] = -94.697963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337547340, states[0] = 19.493206, states[40]= 0.003520
Saving checkpoint... 
Iteration: 1346880242, states[0] = -94.802319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358497069, states[0] = -94.845788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368876134, states[0] = -94.799575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379034786, states[0] = 24.004091, states[40]= 0.002661
Saving checkpoint... 
Iteration: 1389498525, states[0] = -94.845963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399709129, states[0] = -94.495798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410050074, states[0] = 18.455917, states[40]= 0.003733
Saving checkpoint... 
Iteration: 1420229372, states[0] = -94.565748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429896079, states[0] = -94.811361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440089042, states[0] = -0.294727, states[40]= 0.004930
Saving checkpoint... 
Iteration: 1450356858, states[0] = -94.785154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460695240, states[0] = -94.418079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470895622, states[0] = -94.810979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480952196, states[0] = -94.834395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491234916, states[0] = -94.582487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1501111815, states[0] = -2.746003, states[40]= 0.005948
Saving checkpoint... 
Iteration: 1511625413, states[0] = -53.996531, states[40]= 0.000095
Saving checkpoint... 
Iteration: 1522095026, states[0] = -12.144591, states[40]= 0.002781
Saving checkpoint... 
Iteration: 1532635974, states[0] = -94.823283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1543078637, states[0] = 7.424916, states[40]= 0.004830
Saving checkpoint... 
Iteration: 1553632261, states[0] = -30.659609, states[40]= 0.001303
Saving checkpoint... 
Iteration: 1563744797, states[0] = -94.647624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1574114726, states[0] = -12.753744, states[40]= 0.002110
Saving checkpoint... 
Iteration: 1583844970, states[0] = -94.556478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1594073233, states[0] = -94.533630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1604509829, states[0] = -94.512429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1614669089, states[0] = -50.070701, states[40]= 0.000118
Saving checkpoint... 
Iteration: 1625071745, states[0] = 14.181893, states[40]= 0.004416
Saving checkpoint... 
Iteration: 1635318781, states[0] = -94.286313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1645705176, states[0] = -94.453410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1655124760, states[0] = -13.657055, states[40]= 0.001964
Saving checkpoint... 
Iteration: 1664704627, states[0] = -94.431730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1674156146, states[0] = -94.434101, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.302757
 - CaMKt in component CaMK (millimolar): 0.001133
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.426377
 - nass in component intracellular_ions (millimolar): 6.426464
 - ki in component intracellular_ions (millimolar): 145.475619
 - kss in component intracellular_ions (millimolar): 145.475609
 - cansr in component intracellular_ions (millimolar): 1.568464
 - cajsr in component intracellular_ions (millimolar): 1.568444
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003844
 - hf in component INa (dimensionless): 0.869209
 - hs in component INa (dimensionless): 0.869209
 - j in component INa (dimensionless): 0.869210
 - hsp in component INa (dimensionless): 0.705838
 - jp in component INa (dimensionless): 0.869211
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.713088
 - hLp in component INaL (dimensionless): 0.520518
 - a in component Ito (dimensionless): 0.000649
 - iF in component Ito (dimensionless): 0.999855
 - iS in component Ito (dimensionless): 0.997693
 - ap in component Ito (dimensionless): 0.000331
 - iFp in component Ito (dimensionless): 0.999855
 - iSp in component Ito (dimensionless): 0.999231
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998802
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003017
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001884
 - xs1 in component IKs (dimensionless): 0.023617
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997490
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:53:55 (15748): called boinc_finish(0)

</stderr_txt>
]]>


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