𝕏

Task 55429333

Name HuVeMOp_20240630122545046526_ORdGradInc_k_25-Pueyo_APDR-conf_718_1
Workunit 26321067
Created 30 Jun 2024, 10:25:57 UTC
Sent 30 Jun 2024, 11:53:13 UTC
Report deadline 3 Jul 2024, 21:29:13 UTC
Received 30 Jun 2024, 14:24:41 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241023
Run time 2 hours 31 min 9 sec
CPU time 2 hours 29 min
Validate state Valid
Credit 60.63
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.25 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122545046526_ORdGradInc_k_25-Pueyo_APDR-conf_718.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122545046526_ORdGradInc_k_25-Pueyo_APDR-conf_718_1_r1376073763_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122545046526_ORdGradInc_k_25-Pueyo_APDR-conf_718_1_r1376073763_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 107.109700
     * GNaL_b in INaL: 0.007302
     * Gto_b in Ito: 0.074719
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031219
     * GKs_b in IKs: 0.001877
     * GK1_b in IK1: 0.147151
     * Gncx_b in INaCa_i: 0.000958
     * Pnak_b in INaK: 72.987171
     * GKb_b in IKb: 0.003699
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.026444
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15023307, states[0] = 21.072308, states[40]= 0.008203
Saving checkpoint... 
Iteration: 30299044, states[0] = -94.791988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45164441, states[0] = -87.920779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60387307, states[0] = -94.806506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75222706, states[0] = -94.644309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89739670, states[0] = -94.668441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103690731, states[0] = -94.560401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117372641, states[0] = -94.781647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131160519, states[0] = -78.827853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145775266, states[0] = -94.708969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160188153, states[0] = -94.536336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174566596, states[0] = 6.134879, states[40]= 0.004869
Saving checkpoint... 
Iteration: 188490093, states[0] = -94.808463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202203037, states[0] = -94.590497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215816784, states[0] = -94.745714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230188337, states[0] = -94.536487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244262065, states[0] = -94.691261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258931710, states[0] = -94.797003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273591605, states[0] = -8.536622, states[40]= 0.002653
Saving checkpoint... 
Iteration: 287894579, states[0] = -94.786006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301523651, states[0] = 21.841539, states[40]= 0.008051
Saving checkpoint... 
Iteration: 315183393, states[0] = -94.454628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328983561, states[0] = -94.806957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343283916, states[0] = -94.716454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357309397, states[0] = -94.739714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371016127, states[0] = 23.521344, states[40]= 0.016177
Saving checkpoint... 
Iteration: 384651311, states[0] = -66.168602, states[40]= 0.000002
Saving checkpoint... 
Iteration: 398323035, states[0] = -94.749902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412056584, states[0] = 10.376150, states[40]= 0.005053
Saving checkpoint... 
Iteration: 425735301, states[0] = -94.651494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439841428, states[0] = -94.761642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454500501, states[0] = -21.375050, states[40]= 0.000017
Saving checkpoint... 
Iteration: 469683873, states[0] = -94.467458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484881483, states[0] = -94.780987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499875588, states[0] = -94.778574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514447412, states[0] = -94.800380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528787230, states[0] = -94.719717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543514525, states[0] = 23.843358, states[40]= 0.020944
Saving checkpoint... 
Iteration: 558529789, states[0] = 20.119195, states[40]= 0.006456
Saving checkpoint... 
Iteration: 573122898, states[0] = -36.575916, states[40]= 0.000225
Saving checkpoint... 
Iteration: 588100987, states[0] = -16.670707, states[40]= 0.001275
Saving checkpoint... 
Iteration: 603227645, states[0] = -94.638137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618506581, states[0] = 27.634030, states[40]= 0.110671
Saving checkpoint... 
Iteration: 633482014, states[0] = -94.806540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648664137, states[0] = -84.110681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663723681, states[0] = -94.630900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678784378, states[0] = -94.716731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693335452, states[0] = -94.757902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708552338, states[0] = 12.058888, states[40]= 0.005115
Saving checkpoint... 
Iteration: 723591262, states[0] = -8.260601, states[40]= 0.002713
Saving checkpoint... 
Iteration: 738486126, states[0] = -94.807090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753768688, states[0] = -94.699151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768376954, states[0] = -94.778987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782457080, states[0] = -94.802179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796697710, states[0] = -94.577486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811045082, states[0] = 14.835215, states[40]= 0.005272
Saving checkpoint... 
Iteration: 825232139, states[0] = -94.645892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839245695, states[0] = -94.667842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853696490, states[0] = -94.574223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868194971, states[0] = -94.569781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882521864, states[0] = 22.282501, states[40]= 0.008943
Saving checkpoint... 
Iteration: 896216399, states[0] = -94.616964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909647704, states[0] = -62.025078, states[40]= 0.000004
Saving checkpoint... 
Iteration: 923472656, states[0] = -94.804887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936846780, states[0] = -94.764395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950258962, states[0] = -94.686681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963758830, states[0] = -94.686497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977530939, states[0] = 19.764130, states[40]= 0.006283
Saving checkpoint... 
Iteration: 991833114, states[0] = -94.756265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006618061, states[0] = -32.119442, states[40]= 0.000399
Saving checkpoint... 
Iteration: 1021086038, states[0] = -4.381837, states[40]= 0.003544
Saving checkpoint... 
Iteration: 1035524643, states[0] = 21.584832, states[40]= 0.007675
Saving checkpoint... 
Iteration: 1049952298, states[0] = -94.801079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064843150, states[0] = -94.762274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080199630, states[0] = -94.582009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095326058, states[0] = -94.751578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109618101, states[0] = -32.155908, states[40]= 0.000397
Saving checkpoint... 
Iteration: 1124138796, states[0] = -52.424220, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1138434179, states[0] = -94.797031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152545628, states[0] = 14.630482, states[40]= 0.005255
Saving checkpoint... 
Iteration: 1166697262, states[0] = -94.576110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181230020, states[0] = -94.642002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195584800, states[0] = -3.546529, states[40]= 0.003709
Saving checkpoint... 
Iteration: 1210277003, states[0] = -94.708524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224543174, states[0] = 15.544592, states[40]= 0.005336
Saving checkpoint... 
Iteration: 1238819238, states[0] = -94.746705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252871311, states[0] = -94.776304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266964640, states[0] = -94.803304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280969674, states[0] = -94.804177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294883266, states[0] = -94.781216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308484313, states[0] = -94.806492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322143385, states[0] = -57.303681, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1335910643, states[0] = -94.790583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349631129, states[0] = -44.516002, states[40]= 0.000070
Saving checkpoint... 
Iteration: 1363451838, states[0] = -94.800803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378015529, states[0] = 23.641041, states[40]= 0.017724
Saving checkpoint... 
Iteration: 1392597051, states[0] = -13.148060, states[40]= 0.001754
Saving checkpoint... 
Iteration: 1406530720, states[0] = 19.832535, states[40]= 0.006314
Saving checkpoint... 
Iteration: 1420771827, states[0] = -94.702496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435336872, states[0] = -94.758342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450052193, states[0] = 12.115638, states[40]= 0.005117
Saving checkpoint... 
Iteration: 1464673020, states[0] = -92.908946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479052619, states[0] = 11.949147, states[40]= 0.005111
Saving checkpoint... 
Iteration: 1493358953, states[0] = -94.770430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1507692103, states[0] = -94.924254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1521832563, states[0] = -95.013814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1535807121, states[0] = -39.660523, states[40]= 0.000146
Saving checkpoint... 
Iteration: 1549851059, states[0] = 8.526152, states[40]= 0.005738
Saving checkpoint... 
Iteration: 1564024284, states[0] = -60.315515, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1578622101, states[0] = 21.528592, states[40]= 0.010115
Saving checkpoint... 
Iteration: 1592948774, states[0] = -95.071836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1607208113, states[0] = -41.898508, states[40]= 0.000106
Saving checkpoint... 
Iteration: 1621286447, states[0] = -19.220373, states[40]= 0.001138
Saving checkpoint... 
Iteration: 1635628899, states[0] = 18.858104, states[40]= 0.007667
Saving checkpoint... 
Iteration: 1649655072, states[0] = -95.082797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1664032827, states[0] = -95.053876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1678508314, states[0] = 26.838385, states[40]= 0.074481
Saving checkpoint... 
Iteration: 1692784253, states[0] = -94.960327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1706851367, states[0] = -94.067450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1720817125, states[0] = 23.151195, states[40]= 0.015677
Saving checkpoint... 
Iteration: 1734713801, states[0] = -48.456899, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1748706277, states[0] = 29.191599, states[40]= 0.106279
Saving checkpoint... 
Iteration: 1762702372, states[0] = -95.000913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1777031833, states[0] = -70.876304, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1791738325, states[0] = -81.049312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1806956651, states[0] = -94.861158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1821816041, states[0] = -94.784769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1836571881, states[0] = 3.129251, states[40]= 0.004679
Saving checkpoint... 
Iteration: 1851674081, states[0] = -93.639885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1866961327, states[0] = -94.813033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1882050357, states[0] = 12.733043, states[40]= 0.005151
Saving checkpoint... 
Iteration: 1897026408, states[0] = 21.066752, states[40]= 0.007141
Saving checkpoint... 
Iteration: 1911581475, states[0] = -1.526040, states[40]= 0.004071
Saving checkpoint... 
Iteration: 1926598589, states[0] = -14.594030, states[40]= 0.001533
Saving checkpoint... 
Iteration: 1941882506, states[0] = -94.781628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1956969245, states[0] = -94.804384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1972058427, states[0] = 9.621836, states[40]= 0.005027
Saving checkpoint... 
Iteration: 1987162129, states[0] = -81.057967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2002395202, states[0] = -94.785338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2017164007, states[0] = -83.924141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2031770023, states[0] = -94.700036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2046319876, states[0] = -94.746698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2061099132, states[0] = -15.001115, states[40]= 0.001476
Saving checkpoint... 
Iteration: 2075563684, states[0] = 7.425593, states[40]= 0.004936
Saving checkpoint... 
Iteration: 2089820772, states[0] = -94.747280, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.684022
 - CaMKt in component CaMK (millimolar): 0.006962
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.547735
 - nass in component intracellular_ions (millimolar): 6.547794
 - ki in component intracellular_ions (millimolar): 145.430618
 - kss in component intracellular_ions (millimolar): 145.430600
 - cansr in component intracellular_ions (millimolar): 1.311762
 - cajsr in component intracellular_ions (millimolar): 1.273422
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003699
 - hf in component INa (dimensionless): 0.876169
 - hs in component INa (dimensionless): 0.876164
 - j in component INa (dimensionless): 0.876131
 - hsp in component INa (dimensionless): 0.718648
 - jp in component INa (dimensionless): 0.876109
 - mL in component INaL (dimensionless): 0.000052
 - hL in component INaL (dimensionless): 0.702456
 - hLp in component INaL (dimensionless): 0.440591
 - a in component Ito (dimensionless): 0.000633
 - iF in component Ito (dimensionless): 0.999865
 - iS in component Ito (dimensionless): 0.613543
 - ap in component Ito (dimensionless): 0.000322
 - iFp in component Ito (dimensionless): 0.999865
 - iSp in component Ito (dimensionless): 0.686153
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.929352
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999865
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001615
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.352347
 - xs1 in component IKs (dimensionless): 0.251426
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997394
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:24:31 (595694): called boinc_finish(0)

</stderr_txt>
]]>


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