𝕏

Task 55429331

Name HuVeMOp_20240630122545046526_ORdGradInc_k_25-Pueyo_APDR-conf_118_1
Workunit 26321066
Created 30 Jun 2024, 10:25:57 UTC
Sent 30 Jun 2024, 11:53:13 UTC
Report deadline 3 Jul 2024, 21:29:13 UTC
Received 30 Jun 2024, 14:29:10 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241023
Run time 2 hours 35 min 39 sec
CPU time 2 hours 33 min 20 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.25 MB
Peak swap size 3.82 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122545046526_ORdGradInc_k_25-Pueyo_APDR-conf_118.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122545046526_ORdGradInc_k_25-Pueyo_APDR-conf_118_1_r1603173609_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630122545046526_ORdGradInc_k_25-Pueyo_APDR-conf_118_1_r1603173609_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 91.690009
     * GNaL_b in INaL: 0.005318
     * Gto_b in Ito: 0.090956
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031116
     * GKs_b in IKs: 0.002132
     * GK1_b in IK1: 0.166565
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 67.482431
     * GKb_b in IKb: 0.003728
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.048802
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13952730, states[0] = -95.181310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27709516, states[0] = -94.985433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41653852, states[0] = -78.807567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55317211, states[0] = -95.082140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69212966, states[0] = -94.958825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83269967, states[0] = -95.033658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97864099, states[0] = -95.092867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112592151, states[0] = -10.775680, states[40]= 0.002141
Saving checkpoint... 
Iteration: 127116875, states[0] = -33.679282, states[40]= 0.000312
Saving checkpoint... 
Iteration: 141092442, states[0] = -10.927364, states[40]= 0.002111
Saving checkpoint... 
Iteration: 155164155, states[0] = -91.511693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169410626, states[0] = -95.103291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183810808, states[0] = -95.060022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198264783, states[0] = -95.020283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212894851, states[0] = -95.098386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227291991, states[0] = -95.045695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241667868, states[0] = -93.695024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255842234, states[0] = -95.077784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270038505, states[0] = 16.068550, states[40]= 0.005011
Saving checkpoint... 
Iteration: 284483488, states[0] = -95.116224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299138494, states[0] = -55.557362, states[40]= 0.000011
Saving checkpoint... 
Iteration: 313930599, states[0] = -95.107228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328472785, states[0] = -95.114699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342810409, states[0] = -95.059189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357029787, states[0] = 18.750246, states[40]= 0.005655
Saving checkpoint... 
Iteration: 371712686, states[0] = -94.945692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386380003, states[0] = -95.093293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400208674, states[0] = -94.938283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414817966, states[0] = -95.064061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429430266, states[0] = -95.107062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443692691, states[0] = -94.906197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457829308, states[0] = -95.070766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471689233, states[0] = -94.898123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485614280, states[0] = -31.080840, states[40]= 0.000423
Saving checkpoint... 
Iteration: 499618834, states[0] = -35.398044, states[40]= 0.000250
Saving checkpoint... 
Iteration: 513829649, states[0] = -95.070916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528182331, states[0] = -94.873258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542241163, states[0] = -94.990847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556157650, states[0] = -81.853373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570271676, states[0] = -95.026892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584149986, states[0] = -69.439300, states[40]= 0.000001
Saving checkpoint... 
Iteration: 597932274, states[0] = -95.107368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611505149, states[0] = 26.326232, states[40]= 0.151990
Saving checkpoint... 
Iteration: 625232663, states[0] = -94.978558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638811467, states[0] = -95.059682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652570437, states[0] = 3.509274, states[40]= 0.004502
Saving checkpoint... 
Iteration: 666386569, states[0] = -95.095282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680195199, states[0] = -94.911421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693788084, states[0] = -95.041974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707475294, states[0] = -95.114777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721462103, states[0] = -95.112781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735064817, states[0] = 6.075454, states[40]= 0.004645
Saving checkpoint... 
Iteration: 749009626, states[0] = 22.322860, states[40]= 0.055822
Saving checkpoint... 
Iteration: 763216974, states[0] = -94.953024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777455589, states[0] = -95.111666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791514639, states[0] = 21.636517, states[40]= 0.018330
Saving checkpoint... 
Iteration: 805679360, states[0] = -94.848350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819919343, states[0] = -95.104305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833986746, states[0] = -95.116221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848041619, states[0] = 15.007994, states[40]= 0.004906
Saving checkpoint... 
Iteration: 862230893, states[0] = -94.975705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876629995, states[0] = -46.478801, states[40]= 0.000049
Saving checkpoint... 
Iteration: 891264663, states[0] = -95.019348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905771694, states[0] = -95.026667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920266726, states[0] = -95.021533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934083842, states[0] = -4.109378, states[40]= 0.003502
Saving checkpoint... 
Iteration: 947962884, states[0] = -95.112742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961652334, states[0] = -72.876221, states[40]= 0.000001
Saving checkpoint... 
Iteration: 975211220, states[0] = -94.942580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988545531, states[0] = 13.623158, states[40]= 0.004824
Saving checkpoint... 
Iteration: 1001940561, states[0] = -95.108761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015414464, states[0] = -95.102975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028700812, states[0] = -94.922640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042009968, states[0] = 22.240805, states[40]= 0.051329
Saving checkpoint... 
Iteration: 1055130451, states[0] = -46.952607, states[40]= 0.000046
Saving checkpoint... 
Iteration: 1068436251, states[0] = -95.107853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081934469, states[0] = -95.107477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095336773, states[0] = -95.074344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108808312, states[0] = -95.057194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122445308, states[0] = -95.109582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135884246, states[0] = -95.094183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149265540, states[0] = -95.020104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162674119, states[0] = -94.705467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176261583, states[0] = -95.015759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189827870, states[0] = -95.069423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203442060, states[0] = -95.108907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217158728, states[0] = -83.771169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230923185, states[0] = -95.104908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244533321, states[0] = 17.725929, states[40]= 0.005311
Saving checkpoint... 
Iteration: 1258336446, states[0] = -95.074056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272388886, states[0] = -95.095586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286355398, states[0] = -95.083093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300079300, states[0] = -1.204524, states[40]= 0.003994
Saving checkpoint... 
Iteration: 1313768423, states[0] = -95.023027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327440644, states[0] = -95.108542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340990645, states[0] = -95.116341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355054004, states[0] = 10.477895, states[40]= 0.004750
Saving checkpoint... 
Iteration: 1369712550, states[0] = -94.944717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383930491, states[0] = -95.106421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398067744, states[0] = 4.770085, states[40]= 0.004582
Saving checkpoint... 
Iteration: 1412223862, states[0] = -94.964187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426401321, states[0] = -95.099192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440637655, states[0] = -54.635584, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1454914541, states[0] = -95.102677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469044345, states[0] = 14.048107, states[40]= 0.004844
Saving checkpoint... 
Iteration: 1483251527, states[0] = -95.003708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497544283, states[0] = 14.070218, states[40]= 0.004845
Saving checkpoint... 
Iteration: 1511816913, states[0] = -52.937976, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1525826259, states[0] = 18.939060, states[40]= 0.007349
Saving checkpoint... 
Iteration: 1539834289, states[0] = -95.309586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1554046509, states[0] = 9.866875, states[40]= 0.005553
Saving checkpoint... 
Iteration: 1568164276, states[0] = -0.436008, states[40]= 0.004649
Saving checkpoint... 
Iteration: 1582373428, states[0] = -95.215491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1596456740, states[0] = -95.157335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1610492077, states[0] = -27.931525, states[40]= 0.000561
Saving checkpoint... 
Iteration: 1624531711, states[0] = 16.484976, states[40]= 0.006413
Saving checkpoint... 
Iteration: 1638558682, states[0] = -95.356384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1652641576, states[0] = -95.338741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1667077859, states[0] = -95.373394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1681325150, states[0] = -67.372743, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1695714425, states[0] = -53.375098, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1710179528, states[0] = -95.235483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1724486218, states[0] = -21.701374, states[40]= 0.000909
Saving checkpoint... 
Iteration: 1738582011, states[0] = -17.130938, states[40]= 0.001337
Saving checkpoint... 
Iteration: 1752253729, states[0] = -95.352322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1765842105, states[0] = 11.800265, states[40]= 0.005713
Saving checkpoint... 
Iteration: 1779786526, states[0] = -95.251080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1793690653, states[0] = -95.382872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807484138, states[0] = -95.165514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1821277249, states[0] = -95.067390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1834939276, states[0] = -95.132637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1848727914, states[0] = -94.987355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1862662218, states[0] = -90.355909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1876582308, states[0] = -3.363874, states[40]= 0.003647
Saving checkpoint... 
Iteration: 1890270420, states[0] = -95.029698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1904211357, states[0] = -94.945542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1918209495, states[0] = -94.940953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932061780, states[0] = 7.338177, states[40]= 0.004690
Saving checkpoint... 
Iteration: 1945854066, states[0] = -95.082988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1959504399, states[0] = 28.371054, states[40]= 0.165496
Saving checkpoint... 
Iteration: 1973371414, states[0] = -95.089459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1987374190, states[0] = -95.090319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2001312579, states[0] = -95.059577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2015340482, states[0] = -95.075649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2029488741, states[0] = -95.115632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2043818526, states[0] = -95.063224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2058291971, states[0] = -95.044191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2072722874, states[0] = -94.962040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2087110325, states[0] = -27.369340, states[40]= 0.000600
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.992706
 - CaMKt in component CaMK (millimolar): 0.007179
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.602711
 - nass in component intracellular_ions (millimolar): 6.602771
 - ki in component intracellular_ions (millimolar): 145.372392
 - kss in component intracellular_ions (millimolar): 145.372372
 - cansr in component intracellular_ions (millimolar): 1.318841
 - cajsr in component intracellular_ions (millimolar): 1.280351
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003585
 - hf in component INa (dimensionless): 0.881568
 - hs in component INa (dimensionless): 0.881564
 - j in component INa (dimensionless): 0.881536
 - hsp in component INa (dimensionless): 0.728792
 - jp in component INa (dimensionless): 0.881518
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711764
 - hLp in component INaL (dimensionless): 0.453077
 - a in component Ito (dimensionless): 0.000620
 - iF in component Ito (dimensionless): 0.999872
 - iS in component Ito (dimensionless): 0.619459
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999872
 - iSp in component Ito (dimensionless): 0.694287
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934512
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999883
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001618
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.320545
 - xs1 in component IKs (dimensionless): 0.245085
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997313
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:29:01 (595695): called boinc_finish(0)

</stderr_txt>
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