𝕏

Task 55429059

Name HuVeMOp_20240630012025727263_ORdGradInc_k_25-Pueyo_APDR-conf_252_2
Workunit 26292650
Created 30 Jun 2024, 10:23:05 UTC
Sent 30 Jun 2024, 11:51:51 UTC
Report deadline 3 Jul 2024, 21:27:51 UTC
Received 2 Jul 2024, 20:14:59 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 234951
Run time 2 hours 31 min 4 sec
CPU time 2 hours 30 min 44 sec
Validate state Valid
Credit 63.66
Device peak FLOPS 4.40 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630012025727263_ORdGradInc_k_25-Pueyo_APDR-conf_252.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630012025727263_ORdGradInc_k_25-Pueyo_APDR-conf_252_2_r1956638442_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630012025727263_ORdGradInc_k_25-Pueyo_APDR-conf_252_2_r1956638442_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 92.547788
     * GNaL_b in INaL: 0.006565
     * Gto_b in Ito: 0.070887
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033353
     * GKs_b in IKs: 0.002061
     * GK1_b in IK1: 0.168940
     * Gncx_b in INaCa_i: 0.000978
     * Pnak_b in INaK: 68.324917
     * GKb_b in IKb: 0.003768
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029508
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14044240, states[0] = 13.200267, states[40]= 0.005290
Saving checkpoint... 
Iteration: 28435402, states[0] = -95.108396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42690479, states[0] = -94.896907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56687458, states[0] = -94.881455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70741819, states[0] = -94.967388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84743371, states[0] = -94.965591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99410655, states[0] = -95.067310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114935794, states[0] = -95.071229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128989332, states[0] = -95.078650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143853327, states[0] = -95.044729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158427223, states[0] = -95.067248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172638321, states[0] = -61.117746, states[40]= 0.000004
Saving checkpoint... 
Iteration: 187594362, states[0] = -14.976469, states[40]= 0.001481
Saving checkpoint... 
Iteration: 201745180, states[0] = -94.960633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216076807, states[0] = -0.909351, states[40]= 0.004177
Saving checkpoint... 
Iteration: 230838869, states[0] = -95.036793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245458628, states[0] = -95.072312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259917185, states[0] = -95.064100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274719842, states[0] = -94.924088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288790822, states[0] = -95.006355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303960413, states[0] = -95.072510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318157269, states[0] = -90.302968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333118319, states[0] = -38.499033, states[40]= 0.000156
Saving checkpoint... 
Iteration: 347561193, states[0] = 7.143538, states[40]= 0.004929
Saving checkpoint... 
Iteration: 363860734, states[0] = -95.046378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378320566, states[0] = -95.026701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393578591, states[0] = -2.023688, states[40]= 0.003998
Saving checkpoint... 
Iteration: 408683634, states[0] = -94.855815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422809792, states[0] = -95.019963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439962276, states[0] = -95.072716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456935847, states[0] = -95.068017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472856264, states[0] = -95.044481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489182783, states[0] = -94.853721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505208601, states[0] = -94.904861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519508222, states[0] = 25.846953, states[40]= 0.075378
Saving checkpoint... 
Iteration: 534674508, states[0] = -94.818345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549084294, states[0] = -6.063479, states[40]= 0.003208
Saving checkpoint... 
Iteration: 564154387, states[0] = -86.164019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583282178, states[0] = -94.999011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600085711, states[0] = -7.188589, states[40]= 0.002963
Saving checkpoint... 
Iteration: 614325570, states[0] = -95.029452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628448539, states[0] = -95.070316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643579257, states[0] = -2.457638, states[40]= 0.003923
Saving checkpoint... 
Iteration: 657770512, states[0] = -94.988260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673797915, states[0] = -95.011548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688073341, states[0] = 1.117206, states[40]= 0.004450
Saving checkpoint... 
Iteration: 702018155, states[0] = 22.856728, states[40]= 0.012210
Saving checkpoint... 
Iteration: 716224459, states[0] = -94.931101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730717177, states[0] = -94.919449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747503946, states[0] = 33.499453, states[40]= 0.142058
Saving checkpoint... 
Iteration: 761595816, states[0] = -16.353836, states[40]= 0.001303
Saving checkpoint... 
Iteration: 776326629, states[0] = -95.029954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790538203, states[0] = 16.599014, states[40]= 0.005577
Saving checkpoint... 
Iteration: 804567439, states[0] = 4.203402, states[40]= 0.004747
Saving checkpoint... 
Iteration: 819406142, states[0] = -95.060981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833544023, states[0] = 14.346450, states[40]= 0.005297
Saving checkpoint... 
Iteration: 847717763, states[0] = -94.920349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861930422, states[0] = -95.066678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876081658, states[0] = -4.101958, states[40]= 0.003615
Saving checkpoint... 
Iteration: 890585726, states[0] = -7.200647, states[40]= 0.002961
Saving checkpoint... 
Iteration: 905874851, states[0] = -95.051384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920144907, states[0] = -69.936105, states[40]= 0.000001
Saving checkpoint... 
Iteration: 934556311, states[0] = 9.290469, states[40]= 0.005024
Saving checkpoint... 
Iteration: 951141960, states[0] = -65.770793, states[40]= 0.000002
Saving checkpoint... 
Iteration: 965487681, states[0] = -95.075965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981397585, states[0] = -95.058549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995441544, states[0] = -95.068826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012422543, states[0] = -95.064876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026755442, states[0] = -94.972198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041796723, states[0] = -95.010457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056254379, states[0] = -94.970968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070717296, states[0] = -94.919455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084724749, states[0] = -94.931342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099554799, states[0] = 9.935725, states[40]= 0.005050
Saving checkpoint... 
Iteration: 1114822732, states[0] = -95.027554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129617533, states[0] = -37.695994, states[40]= 0.000175
Saving checkpoint... 
Iteration: 1145003464, states[0] = 35.565353, states[40]= 0.137668
Saving checkpoint... 
Iteration: 1159576987, states[0] = -1.013814, states[40]= 0.004161
Saving checkpoint... 
Iteration: 1175913241, states[0] = -95.062589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190761574, states[0] = -94.978852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205108025, states[0] = -28.250458, states[40]= 0.000536
Saving checkpoint... 
Iteration: 1220692740, states[0] = -94.874561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235307821, states[0] = -95.018202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249417946, states[0] = -95.063682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263572462, states[0] = 1.602075, states[40]= 0.004506
Saving checkpoint... 
Iteration: 1278035879, states[0] = 17.462353, states[40]= 0.005745
Saving checkpoint... 
Iteration: 1292405371, states[0] = -95.060514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306594905, states[0] = -15.475129, states[40]= 0.001413
Saving checkpoint... 
Iteration: 1321078710, states[0] = -2.100260, states[40]= 0.003985
Saving checkpoint... 
Iteration: 1336011682, states[0] = 24.358256, states[40]= 0.035149
Saving checkpoint... 
Iteration: 1350503741, states[0] = 34.327951, states[40]= 0.140880
Saving checkpoint... 
Iteration: 1364730853, states[0] = -94.940322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379600090, states[0] = -20.508149, states[40]= 0.000930
Saving checkpoint... 
Iteration: 1395034574, states[0] = 17.935830, states[40]= 0.005858
Saving checkpoint... 
Iteration: 1409603156, states[0] = -23.495820, states[40]= 0.000763
Saving checkpoint... 
Iteration: 1424966543, states[0] = -95.072821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439575187, states[0] = 0.064440, states[40]= 0.004316
Saving checkpoint... 
Iteration: 1454207461, states[0] = -94.902291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469644567, states[0] = -69.433719, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1484496896, states[0] = -95.076765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498451828, states[0] = -95.070407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1512421075, states[0] = -62.233110, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1526681265, states[0] = -95.301923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1541073509, states[0] = -95.306285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1555227507, states[0] = 18.981485, states[40]= 0.007907
Saving checkpoint... 
Iteration: 1571024808, states[0] = -95.267099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1585368661, states[0] = -95.166246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600323797, states[0] = -70.087646, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1616229967, states[0] = -81.363768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1630483332, states[0] = -95.331242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1644666388, states[0] = -3.047138, states[40]= 0.004288
Saving checkpoint... 
Iteration: 1659809507, states[0] = -95.251595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1674592626, states[0] = -95.338321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1690571841, states[0] = -7.903385, states[40]= 0.003163
Saving checkpoint... 
Iteration: 1705104961, states[0] = -95.244488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1720673005, states[0] = -95.181064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1736112743, states[0] = 24.266114, states[40]= 0.029676
Saving checkpoint... 
Iteration: 1751225772, states[0] = -73.697409, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1767325921, states[0] = 19.497459, states[40]= 0.008318
Saving checkpoint... 
Iteration: 1781394801, states[0] = -95.339882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1795640480, states[0] = -94.156243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1810948657, states[0] = -95.113916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1825467590, states[0] = -95.103108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1839531348, states[0] = 18.793937, states[40]= 0.006201
Saving checkpoint... 
Iteration: 1854277723, states[0] = -95.007645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1868425268, states[0] = -95.073692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1884684361, states[0] = -94.862144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1899114841, states[0] = -35.223629, states[40]= 0.000245
Saving checkpoint... 
Iteration: 1915514278, states[0] = 23.702307, states[40]= 0.021224
Saving checkpoint... 
Iteration: 1929491221, states[0] = -95.077286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1943868677, states[0] = -95.049494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1957996998, states[0] = -95.077111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1972087608, states[0] = -8.792126, states[40]= 0.002615
Saving checkpoint... 
Iteration: 1986020610, states[0] = 22.263246, states[40]= 0.009699
Saving checkpoint... 
Iteration: 2000027008, states[0] = 20.472285, states[40]= 0.006976
Saving checkpoint... 
Iteration: 2015039904, states[0] = 15.951073, states[40]= 0.005477
Saving checkpoint... 
Iteration: 2028987710, states[0] = -95.075409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2043669584, states[0] = -94.727723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2057842896, states[0] = -95.037607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2072796669, states[0] = -95.009813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2086911171, states[0] = -95.061532, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.952605
 - CaMKt in component CaMK (millimolar): 0.006669
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.620421
 - nass in component intracellular_ions (millimolar): 6.620480
 - ki in component intracellular_ions (millimolar): 145.361371
 - kss in component intracellular_ions (millimolar): 145.361351
 - cansr in component intracellular_ions (millimolar): 1.295972
 - cajsr in component intracellular_ions (millimolar): 1.258542
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003600
 - hf in component INa (dimensionless): 0.880879
 - hs in component INa (dimensionless): 0.880874
 - j in component INa (dimensionless): 0.880847
 - hsp in component INa (dimensionless): 0.727488
 - jp in component INa (dimensionless): 0.880829
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.712068
 - hLp in component INaL (dimensionless): 0.456002
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.624104
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.699159
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933869
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999884
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001549
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.331801
 - xs1 in component IKs (dimensionless): 0.240937
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997324
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:14:48 (367908): called boinc_finish(0)

</stderr_txt>
]]>