𝕏

Task 55427724

Name HuVeMOp_20240630120543010578_ORdGradInc_k_25-Pueyo_APDR-conf_974_1
Workunit 26320322
Created 30 Jun 2024, 10:06:16 UTC
Sent 30 Jun 2024, 11:36:03 UTC
Report deadline 3 Jul 2024, 21:12:03 UTC
Received 30 Jun 2024, 14:03:44 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241023
Run time 2 hours 27 min 25 sec
CPU time 2 hours 25 min
Validate state Valid
Credit 62.12
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.25 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630120543010578_ORdGradInc_k_25-Pueyo_APDR-conf_974.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630120543010578_ORdGradInc_k_25-Pueyo_APDR-conf_974_1_r556095988_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630120543010578_ORdGradInc_k_25-Pueyo_APDR-conf_974_1_r556095988_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.689408
     * GNaL_b in INaL: 0.007271
     * Gto_b in Ito: 0.081637
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033357
     * GKs_b in IKs: 0.001755
     * GK1_b in IK1: 0.157088
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 67.203149
     * GKb_b in IKb: 0.003746
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.027317
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14793450, states[0] = -94.897093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29331905, states[0] = -94.901053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43810970, states[0] = -94.875104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58283104, states[0] = -94.844104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72974992, states[0] = -94.924802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87675236, states[0] = -94.543682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102607891, states[0] = -25.661489, states[40]= 0.000697
Saving checkpoint... 
Iteration: 117298866, states[0] = -94.847989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131642129, states[0] = -61.042437, states[40]= 0.000005
Saving checkpoint... 
Iteration: 146311053, states[0] = -94.856366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161151467, states[0] = -73.168792, states[40]= 0.000001
Saving checkpoint... 
Iteration: 176489606, states[0] = -94.919175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191786139, states[0] = -94.834562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207054531, states[0] = 10.551380, states[40]= 0.004976
Saving checkpoint... 
Iteration: 222109725, states[0] = -27.211424, states[40]= 0.000624
Saving checkpoint... 
Iteration: 237402498, states[0] = -94.900509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252397803, states[0] = -94.898996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267251935, states[0] = -94.795108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282534311, states[0] = 18.027051, states[40]= 0.005638
Saving checkpoint... 
Iteration: 297679341, states[0] = -94.623631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313090977, states[0] = -9.843214, states[40]= 0.002382
Saving checkpoint... 
Iteration: 327836579, states[0] = -94.872122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342171469, states[0] = -94.254384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356229871, states[0] = -94.761549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370065211, states[0] = 6.022571, states[40]= 0.004816
Saving checkpoint... 
Iteration: 384313127, states[0] = -94.856807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399100653, states[0] = -18.686684, states[40]= 0.001079
Saving checkpoint... 
Iteration: 413644701, states[0] = -64.028786, states[40]= 0.000003
Saving checkpoint... 
Iteration: 428151586, states[0] = -73.285286, states[40]= 0.000001
Saving checkpoint... 
Iteration: 442019911, states[0] = 21.917052, states[40]= 0.009764
Saving checkpoint... 
Iteration: 455830204, states[0] = -94.868224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469762155, states[0] = -94.808120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484154815, states[0] = -78.359328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498757928, states[0] = -94.802818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513706560, states[0] = -94.717961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528376152, states[0] = -94.891030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542526755, states[0] = 20.302578, states[40]= 0.006667
Saving checkpoint... 
Iteration: 556430949, states[0] = -94.907931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570369134, states[0] = -94.888130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584399846, states[0] = -94.899389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598864039, states[0] = -94.885903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612654254, states[0] = -77.442789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626440157, states[0] = -94.909966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640291019, states[0] = -94.838579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654166861, states[0] = -93.150820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668081091, states[0] = -2.407915, states[40]= 0.003915
Saving checkpoint... 
Iteration: 681989381, states[0] = -94.918431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696865388, states[0] = -94.886434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711723381, states[0] = -94.750045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726989813, states[0] = -94.918460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742278414, states[0] = -94.826259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757273113, states[0] = -94.820608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772006517, states[0] = 26.240685, states[40]= 0.116348
Saving checkpoint... 
Iteration: 786464884, states[0] = -94.914629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801557928, states[0] = 9.169697, states[40]= 0.004937
Saving checkpoint... 
Iteration: 816662807, states[0] = -90.339411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831398060, states[0] = -94.898658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846634409, states[0] = -52.122631, states[40]= 0.000021
Saving checkpoint... 
Iteration: 861611698, states[0] = -29.065246, states[40]= 0.000533
Saving checkpoint... 
Iteration: 876813882, states[0] = -94.857031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892294858, states[0] = -94.841844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907491122, states[0] = -94.918517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922723750, states[0] = -94.750564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938003344, states[0] = 35.590803, states[40]= 0.148542
Saving checkpoint... 
Iteration: 953232782, states[0] = -94.765992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968438061, states[0] = -94.909284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983119325, states[0] = -36.353672, states[40]= 0.000228
Saving checkpoint... 
Iteration: 998462693, states[0] = -94.914111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013832974, states[0] = -94.869542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028209141, states[0] = -94.722831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042437810, states[0] = -94.909180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056735799, states[0] = -94.770799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070997342, states[0] = -94.919211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085240653, states[0] = -94.778332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099472482, states[0] = -94.915677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114258105, states[0] = -94.802638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128947720, states[0] = -94.911215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143365718, states[0] = -94.886285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157076767, states[0] = 0.207693, states[40]= 0.004311
Saving checkpoint... 
Iteration: 1170695171, states[0] = -94.693395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184534783, states[0] = 17.871922, states[40]= 0.005600
Saving checkpoint... 
Iteration: 1198133147, states[0] = -50.722506, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1211677744, states[0] = -94.596911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225279852, states[0] = -94.827420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239536017, states[0] = 17.459288, states[40]= 0.005509
Saving checkpoint... 
Iteration: 1254434252, states[0] = -94.908241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268968607, states[0] = -94.914938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283596344, states[0] = -14.657930, states[40]= 0.001525
Saving checkpoint... 
Iteration: 1298257210, states[0] = -94.801371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312965683, states[0] = -94.914420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328522655, states[0] = 21.328280, states[40]= 0.007990
Saving checkpoint... 
Iteration: 1343874791, states[0] = -94.889953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358717079, states[0] = -94.738044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373782466, states[0] = -94.829955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388903049, states[0] = -94.899859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403991741, states[0] = -94.918273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419188773, states[0] = -94.677652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434097514, states[0] = -15.745010, states[40]= 0.001380
Saving checkpoint... 
Iteration: 1449204294, states[0] = -94.712695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464271506, states[0] = -94.818371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479548513, states[0] = 12.913116, states[40]= 0.005052
Saving checkpoint... 
Iteration: 1494787849, states[0] = -94.835082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1510190104, states[0] = -95.154027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1525434055, states[0] = -95.113836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1540703471, states[0] = -95.076454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1555829864, states[0] = 17.893944, states[40]= 0.007162
Saving checkpoint... 
Iteration: 1571100007, states[0] = -94.336811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1586543712, states[0] = -93.472258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1601119081, states[0] = 21.690714, states[40]= 0.012007
Saving checkpoint... 
Iteration: 1616526313, states[0] = -69.245951, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1631517192, states[0] = -56.943970, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1646752563, states[0] = 6.691674, states[40]= 0.005559
Saving checkpoint... 
Iteration: 1661734132, states[0] = 15.905572, states[40]= 0.006607
Saving checkpoint... 
Iteration: 1676864627, states[0] = -95.004605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1692256113, states[0] = -95.175616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1707204336, states[0] = -95.100002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1722115904, states[0] = -55.380506, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1737120424, states[0] = -61.196481, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1752019955, states[0] = 21.390997, states[40]= 0.011097
Saving checkpoint... 
Iteration: 1767017264, states[0] = 22.207861, states[40]= 0.014601
Saving checkpoint... 
Iteration: 1781875665, states[0] = -95.036085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1796798182, states[0] = -34.504691, states[40]= 0.000287
Saving checkpoint... 
Iteration: 1811803035, states[0] = -94.897984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1826810591, states[0] = -94.888080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1841914617, states[0] = -94.924924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856863467, states[0] = -94.898957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1871844008, states[0] = -94.884314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1886942021, states[0] = -94.915301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1901898107, states[0] = -94.901658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1916914214, states[0] = -94.905112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931896018, states[0] = -94.898765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1946934101, states[0] = -94.908690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1961701334, states[0] = -94.706776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1976614382, states[0] = -31.629737, states[40]= 0.000410
Saving checkpoint... 
Iteration: 1991517391, states[0] = 22.387794, states[40]= 0.012849
Saving checkpoint... 
Iteration: 2006857015, states[0] = -94.881865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022189163, states[0] = -94.678383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2037467986, states[0] = -94.914343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2052671611, states[0] = -94.269619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067735951, states[0] = -94.770344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2082768663, states[0] = -94.814717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2097298335, states[0] = -94.844000, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.794693
 - CaMKt in component CaMK (millimolar): 0.007110
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.729123
 - nass in component intracellular_ions (millimolar): 6.729184
 - ki in component intracellular_ions (millimolar): 145.246177
 - kss in component intracellular_ions (millimolar): 145.246158
 - cansr in component intracellular_ions (millimolar): 1.321971
 - cajsr in component intracellular_ions (millimolar): 1.283738
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003658
 - hf in component INa (dimensionless): 0.878129
 - hs in component INa (dimensionless): 0.878124
 - j in component INa (dimensionless): 0.878093
 - hsp in component INa (dimensionless): 0.722311
 - jp in component INa (dimensionless): 0.878072
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.706760
 - hLp in component INaL (dimensionless): 0.447860
 - a in component Ito (dimensionless): 0.000628
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.618997
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.693041
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.932696
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999878
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001646
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.338387
 - xs1 in component IKs (dimensionless): 0.245640
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997365
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:03:33 (595514): called boinc_finish(0)

</stderr_txt>
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